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Gene : Dcr-2 D. melanogaster
DB identifier  ? FBgn0034246 Secondary Identifier  ? CG6493
Name  ? Dicer-2 Source  FlyBase
  • synonyms:
  • CG6493,
  • DICER-2,
  • Dicer 2,
  • DICER,
  • FBan0006493,
  • dic2,
  • DCR2,
  • DICER2,
  • Dcr,
  • FBgn0034246,
  • DCR-2
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Genomics

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36 Alleles

DB identifier Symbol Allele Class Organism
FBal0211026 Dcr-2[Scer\UAS.cDa]   Drosophila melanogaster
FBal0257097 Dcr-2[HMS00062]   Drosophila melanogaster
FBal0247733 Dcr-2[MI00978]   Drosophila melanogaster
FBal0264050 Dcr-2[P8S] hypomorphic allele - genetic evidence Drosophila melanogaster
FBal0264051 Dcr-2[A1453T] hypomorphic allele - molecular evidence, hypomorphic allele - genetic evidence Drosophila melanogaster
FBal0264052 Dcr-2[R269W] hypomorphic allele - genetic evidence Drosophila melanogaster
FBal0264053 Dcr-2[P365L] hypomorphic allele - genetic evidence Drosophila melanogaster
FBal0264054 Dcr-2[P1496L] hypomorphic allele - genetic evidence Drosophila melanogaster
FBal0264055 Dcr-2[L188F] hypomorphic allele - genetic evidence Drosophila melanogaster
FBal0256737 Dcr-2[L812bsX]   Drosophila melanogaster
FBal0184188 Dcr-2[c02925]   Drosophila melanogaster
FBal0160620 Dcr-2[f06544]   Drosophila melanogaster
FBal0213133 Dcr-2[dsRNA.cRa]   Drosophila melanogaster
FBal0242225 Dcr-2[JF02636]   Drosophila melanogaster
FBal0191820 Dcr-2[dsRNA.cJa]   Drosophila melanogaster
FBal0156732 Dcr-2[R416X]   Drosophila melanogaster
FBal0156736 Dcr-2[E1617K.t7.2]   Drosophila melanogaster
FBal0156737 Dcr-2[E1371K.t7.2]   Drosophila melanogaster
FBal0156738 Dcr-2[E1371K.E1617K.t7.2]   Drosophila melanogaster
FBal0156739 Dcr-2[E1237A.t7.2]   Drosophila melanogaster
FBal0156740 Dcr-2[E1210V.t7.2]   Drosophila melanogaster
FBal0156734 Dcr-2[G31R]   Drosophila melanogaster
FBal0189865 Dcr-2[dsRNA.cFa]   Drosophila melanogaster
FBal0156733 Dcr-2[L811fsX] loss of function allele Drosophila melanogaster
FBal0156735 Dcr-2[G173E]   Drosophila melanogaster
FBal0156743 Dcr-2[+t7.2]   Drosophila melanogaster
FBal0152648 Dcr-2[dsRNA.4580-5166]   Drosophila melanogaster
FBal0184187 Dcr-2[dsRNA.cLa]   Drosophila melanogaster
FBal0191187 Dcr-2[dsRNA.cSa]   Drosophila melanogaster
FBal0120985 Dcr-2[dsRNA.cBa]   Drosophila melanogaster

24 Clones

Secondary Identifier DB identifier
EK225660 FBcl0028930
EK160436 FBcl0026306
EK246851 FBcl0028722
EK228508 FBcl0028766
CK02494 FBcl0059703
EC31570 FBcl0066697
EN04356 FBcl0095527
EK231840 FBcl0139838
EK198802 FBcl0139872
GM07586 FBcl0141277
GM05742 FBcl0141305
GM14331 FBcl0145954
LD12933 FBcl0157432
LD44626 FBcl0171456
LP12433 FBcl0185942
SD17147 FBcl0283305
SD11113 FBcl0283312
Dmel_neb_013612_0380_2025 FBcl0375648
FGM216G08 FBcl0390343
FGM301E07 FBcl0392175
FGM324E03 FBcl0393846
102636 FBcl0481319
124313 FBcl0481345
FI15132 FBcl0742409

9 Exons

DB identifier Symbol
FBgn0034246:9 Dcr-2:9
FBgn0034246:8 Dcr-2:8
FBgn0034246:7 Dcr-2:7
FBgn0034246:6 Dcr-2:6
FBgn0034246:5 Dcr-2:5
FBgn0034246:4 Dcr-2:4
FBgn0034246:2 Dcr-2:2
FBgn0034246:1 Dcr-2:1
FBgn0034246:3 Dcr-2:3

2 Transcripts

DB identifier Gene
FBtr0086904 Dcr-2
FBtr0340217 Dcr-2

4 UTRs

Class DB identifier
Organism . Name
FivePrimeUTR FBtr0086904-5-prime-utr Drosophila melanogaster
FivePrimeUTR FBtr0340217-5-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0086904-3-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0340217-3-prime-utr Drosophila melanogaster

Interactions

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Other

4 Pathways

1 Cross References

Identifier
Source . Name
Subject . Primary Identifier
36993 NCBI Entrez Gene identifiers FBgn0034246

10 Data Sets

Name URL
FlyBase data set for Drosophila melanogaster  
TrEMBL data set http://www.ebi.ac.uk/trembl/
Drosophila 12 Genomes Consortium homology  
GenomeRNAi data set  
TreeFam data set  
Panther data set  
IntAct interactions data set  
GO Annotation from FlyBase  
FlyBase fasta data set for Drosophila melanogaster  
Drosophila Cell Line and Developmental Stage Gene and Exon Scores  

55 Expression Scores


Gene . Primary Identifier
Submission . Title
Cell Line . Name
Developmental Stage . Name 		Score
FBgn0034246 Drosophila Cell Line and Developmental Stage Gene and Exon Scores CME L1 761.0
FBgn0034246 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Sg4 716.0
FBgn0034246 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD11 927.0
FBgn0034246 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD20-c2 573.0
FBgn0034246 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD20-c5 1161.0
FBgn0034246 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Kc167 400.0
FBgn0034246 Drosophila Cell Line and Developmental Stage Gene and Exon Scores GM2 1601.0
FBgn0034246 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S2-DRSC 749.0
FBgn0034246 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S2R+ 568.0
FBgn0034246 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S1 984.0
FBgn0034246 Drosophila Cell Line and Developmental Stage Gene and Exon Scores 1182-4H 836.0
FBgn0034246 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD16-c3 411.0
FBgn0034246 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD32 419.0
FBgn0034246 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD17-c3 739.0
FBgn0034246 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD8 1224.0
FBgn0034246 Drosophila Cell Line and Developmental Stage Gene and Exon Scores CME W1 Cl.8+ 938.0
FBgn0034246 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD9 1283.0
FBgn0034246 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmBG1-c1 1046.0
FBgn0034246 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD21 469.0
FBgn0034246 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD4-c1 838.0
FBgn0034246 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmBG3-c2 771.0
FBgn0034246 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S3 876.0
FBgn0034246 Drosophila Cell Line and Developmental Stage Gene and Exon Scores CME W2 1160.0
FBgn0034246 Drosophila Cell Line and Developmental Stage Gene and Exon Scores mbn2 1716.0
FBgn0034246 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmBG2-c2 1257.0
FBgn0034246 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 0-2 h 1129.0
FBgn0034246 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 2-4 h 884.0
FBgn0034246 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 4-6 h 468.0
FBgn0034246 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 6-8 h 545.0
FBgn0034246 Drosophila Cell Line and Developmental Stage Gene and Exon Scores emb 8-10h 367.0

9 Introns

DB identifier
Organism . Name
intron_FBgn0034246:9_FBgn0034246:8 Drosophila melanogaster
intron_FBgn0034246:8_FBgn0034246:7 Drosophila melanogaster
intron_FBgn0034246:7_FBgn0034246:6 Drosophila melanogaster
intron_FBgn0034246:6_FBgn0034246:5 Drosophila melanogaster
intron_FBgn0034246:5_FBgn0034246:4 Drosophila melanogaster
intron_FBgn0034246:4_FBgn0034246:3 Drosophila melanogaster
intron_FBgn0034246:3_FBgn0034246:1 Drosophila melanogaster
intron_FBgn0034246:4_FBgn0034246:2 Drosophila melanogaster
intron_FBgn0034246:2_FBgn0034246:1 Drosophila melanogaster

14 RNAi Results

Screen Gene Phenotype Score Conditions PubMed ID
Lipid storage Dcr-2 none 0.257492864   19067489
Lipid storage Dcr-2 none -0.753302504   19067489
Alternative splicing Dcr-2 none sp   15492211
Cell size and cell-cycle regulation (1) Dcr-2 none sp   16496002
RNAi pathway Dcr-2 Decreased RNAi silencing np   16862146
Muscle morphogenesis and function (1) Dcr-2 none np   20220848
Heat nociception (1) Dcr-2 none -1.17   21074052
Regulated secretory pathway biogenesis (1) Dcr-2 none 9.6   21149569
Heart development and function (1) Dcr-2 none 1   20371351
Serratia marcescens infection (1) Dcr-2 none 0.557692307692307   19520911
Notch pathway regulation (4) Dcr-2 none 0   19363474
Notch pathway regulation (1) Dcr-2 Upregulation of Notch pathway np   20493818
Adiposity regulation (1) Dcr-2 none -0.291   20074523
Hippo pathway regulation Dcr-2 none -0.02   23263283

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