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Gene : gig D. melanogaster

DB identifier  ? FBgn0005198 Secondary Identifier  ? CG6975
Name  ? gigas Source  FlyBase
  • synonyms:
  • l(3)109,
  • FBan0006975,
  • Tuberous sclerosis complex 2,
  • ME 109,
  • TSC2,
  • CG6975,
  • lethal(3)109,
  • C1,
  • Gigas,
  • gig|Tsc2,
  • dTSC2,
  • gig,
  • Tsc2/gig,
  • 6975,
  • tuberin,
  • FBgn0005198

Sequence Feature Displayer

Publication Counts Displayer

Genomics

Gene Ontology Displayer

Homologue Displayer

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Overlapping Features Displayer

Regulatory Regions Displayer

52 Alleles

DB identifier Symbol Allele Class Organism
FBal0220855 gig[G4010]   Drosophila melanogaster
FBal0245379 gig[HM04083]   Drosophila melanogaster
FBal0257873 gig[HMS01217]   Drosophila melanogaster
FBal0246590 gig[E1.16]   Drosophila melanogaster
FBal0196978 gig[MB02535]   Drosophila melanogaster
FBal0248567 gig[Scer\UAS.cTa]   Drosophila melanogaster
FBal0219460 gig[MB08557]   Drosophila melanogaster
FBal0095398 gig[hs.PI]   Drosophila melanogaster
FBal0175665 gig[R884Q.alphaTub]   Drosophila melanogaster
FBal0175666 gig[R622W.alphaTub]   Drosophila melanogaster
FBal0175667 gig[N1698K.alphaTub]   Drosophila melanogaster
FBal0175668 gig[K1693A.alphaTub]   Drosophila melanogaster
FBal0175670 gig[DE.alphaTub]   Drosophila melanogaster
FBal0175673 gig[AA.alphaTub]   Drosophila melanogaster
FBal0175674 gig[4A.alphaTub]   Drosophila melanogaster
FBal0175675 gig[alphaTub.PD]   Drosophila melanogaster
FBal0095404 gig[273]   Drosophila melanogaster
FBal0125006 gig[unspecified]   Drosophila melanogaster
FBal0095405 gig[25]   Drosophila melanogaster
FBal0141110 gig[cRa]   Drosophila melanogaster
FBal0095407 gig[193]   Drosophila melanogaster
FBal0095403 gig[55]   Drosophila melanogaster
FBal0150478 gig[dsRNA.cGa]   Drosophila melanogaster
FBal0095401 gig[57]   Drosophila melanogaster
FBal0095400 gig[5C8]   Drosophila melanogaster
FBal0095406 gig[201]   Drosophila melanogaster
FBal0095399 gig[62]   Drosophila melanogaster
FBal0141111 gig[a.cRa]   Drosophila melanogaster
FBal0095409 gig[02253]   Drosophila melanogaster
FBal0009630 gig[109]   Drosophila melanogaster

76 Clones

Secondary Identifier DB identifier
AT05037 FBcl0016665
EP19162 FBcl0078439
GH02154 FBcl0109239
EK201941 FBcl0126246
EK254618 FBcl0126344
EK201725 FBcl0126350
EK161216 FBcl0126356
EK063244 FBcl0126362
EK139611 FBcl0126370
LD36178 FBcl0166004
LP02390 FBcl0181899
RE53606 FBcl0200603
RE45520 FBcl0200609
RH50482 FBcl0246966
RH74623 FBcl0246968
CK01.60A.C12 FBcl0451825
30397 FBcl0452590
RP003293072 FBcl0692016
RP003603257 FBcl0692006
RP003579612 FBcl0692007
RP003445855 FBcl0692008
RP003279906 FBcl0692009
RP003302365 FBcl0692010
RP003083115 FBcl0692011
RP003125503 FBcl0692012
RP003349858 FBcl0692013
RP003034238 FBcl0692014
RP003318898 FBcl0692015
RP003168745 FBcl0692017
RP003455178 FBcl0692018

16 Exons

DB identifier Symbol
FBgn0005198:1 gig:1
FBgn0005198:2 gig:2
FBgn0005198:3 gig:3
FBgn0005198:4 gig:4
FBgn0005198:5 gig:5
FBgn0005198:6 gig:6
FBgn0005198:7 gig:7
FBgn0005198:8 gig:8
FBgn0005198:9 gig:9
FBgn0005198:10 gig:10
FBgn0005198:12 gig:12
FBgn0005198:13 gig:13
FBgn0005198:14 gig:14
FBgn0005198:15 gig:15
FBgn0005198:16 gig:16
FBgn0005198:11 gig:11

2 Transcripts

DB identifier Gene
FBtr0074819 gig
FBtr0332690 gig

4 UTRs

Class DB identifier
Organism . Name
FivePrimeUTR FBtr0074819-5-prime-utr Drosophila melanogaster
FivePrimeUTR FBtr0332690-5-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0074819-3-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0332690-3-prime-utr Drosophila melanogaster

Interactions

Cytoscape Network Displayer

 

Other

57 Pathways

2 Cross References

Identifier
Source . Name

Subject . Primary Identifier
40201 NCBI Entrez Gene identifiers FBgn0005198
65467 BioGRID FBgn0005198

11 Data Sets

Name URL
FlyBase data set for Drosophila melanogaster  
TrEMBL data set http://www.ebi.ac.uk/trembl/
Drosophila 12 Genomes Consortium homology  
GenomeRNAi data set  
TreeFam data set  
Panther data set  
IntAct interactions data set  
BioGRID interaction data set http://www.thebiogrid.org/downloads.php
GO Annotation from FlyBase  
FlyBase fasta data set for Drosophila melanogaster  
Drosophila Cell Line and Developmental Stage Gene and Exon Scores  

55 Expression Scores


Gene . Primary Identifier

Submission . Title

Cell Line . Name

Developmental Stage . Name
Score
FBgn0005198 Drosophila Cell Line and Developmental Stage Gene and Exon Scores CME L1 1139.0
FBgn0005198 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Sg4 1367.0
FBgn0005198 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD11 795.0
FBgn0005198 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD20-c2 866.0
FBgn0005198 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD20-c5 1244.0
FBgn0005198 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Kc167 897.0
FBgn0005198 Drosophila Cell Line and Developmental Stage Gene and Exon Scores GM2 2386.0
FBgn0005198 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S2-DRSC 927.0
FBgn0005198 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S2R+ 296.0
FBgn0005198 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S1 1129.0
FBgn0005198 Drosophila Cell Line and Developmental Stage Gene and Exon Scores 1182-4H 1123.0
FBgn0005198 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD16-c3 530.0
FBgn0005198 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD32 601.0
FBgn0005198 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD17-c3 418.0
FBgn0005198 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD8 879.0
FBgn0005198 Drosophila Cell Line and Developmental Stage Gene and Exon Scores CME W1 Cl.8+ 894.0
FBgn0005198 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD9 1063.0
FBgn0005198 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmBG1-c1 1031.0
FBgn0005198 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD21 729.0
FBgn0005198 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD4-c1 923.0
FBgn0005198 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmBG3-c2 1184.0
FBgn0005198 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S3 1609.0
FBgn0005198 Drosophila Cell Line and Developmental Stage Gene and Exon Scores CME W2 891.0
FBgn0005198 Drosophila Cell Line and Developmental Stage Gene and Exon Scores mbn2 756.0
FBgn0005198 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmBG2-c2 569.0
FBgn0005198 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 0-2 h 1459.0
FBgn0005198 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 2-4 h 1385.0
FBgn0005198 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 4-6 h 709.0
FBgn0005198 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 6-8 h 712.0
FBgn0005198 Drosophila Cell Line and Developmental Stage Gene and Exon Scores emb 8-10h 629.0

16 Introns

DB identifier
Organism . Name
intron_FBgn0005198:1_FBgn0005198:2 Drosophila melanogaster
intron_FBgn0005198:2_FBgn0005198:3 Drosophila melanogaster
intron_FBgn0005198:3_FBgn0005198:4 Drosophila melanogaster
intron_FBgn0005198:4_FBgn0005198:5 Drosophila melanogaster
intron_FBgn0005198:5_FBgn0005198:6 Drosophila melanogaster
intron_FBgn0005198:6_FBgn0005198:7 Drosophila melanogaster
intron_FBgn0005198:7_FBgn0005198:8 Drosophila melanogaster
intron_FBgn0005198:8_FBgn0005198:9 Drosophila melanogaster
intron_FBgn0005198:9_FBgn0005198:10 Drosophila melanogaster
intron_FBgn0005198:10_FBgn0005198:12 Drosophila melanogaster
intron_FBgn0005198:12_FBgn0005198:13 Drosophila melanogaster
intron_FBgn0005198:13_FBgn0005198:14 Drosophila melanogaster
intron_FBgn0005198:14_FBgn0005198:15 Drosophila melanogaster
intron_FBgn0005198:15_FBgn0005198:16 Drosophila melanogaster
intron_FBgn0005198:9_FBgn0005198:11 Drosophila melanogaster
intron_FBgn0005198:11_FBgn0005198:12 Drosophila melanogaster

32 RNAi Results

Screen Gene Phenotype Score Conditions PubMed ID
Cell size regulation gig none 0.76   19216764
Lipid storage gig none 1.220981313   19067489
Lipid storage gig none 1.951113871   19067489
Lipid storage gig none 0.057444689   19067489
Chlamydia caviae infection gig Decreased Chlamydia caviae infection np   17967059
ERK signaling gig ERK activation reduced strong   17086199
Cell morphology gig Morphology np   14527345
Cell size and cell-cycle regulation (1) gig none sp   16496002
Candida albicans phagocytosis (1) gig Decreased Candida albicans phagocytosis np   16336044
Candida albicans phagocytosis (2) gig Decreased Escherichia coli phagocytosis 34   16336044
Candida albicans phagocytosis (3) gig Decreased latex beads phagocytosis 28   16336044
Hypoxia signaling gig Hypoxia-induced translation inhibition is reduced np   18653470
Combinatorial effect with methyl methanesulphonate (1) gig none sp   19543366
Combinatorial effect with methyl methanesulphonate (2) gig Increased viability with methyl methanesulphonate sp   19543366
Muscle morphogenesis and function (1) gig Weak flyer np   20220848
Heat nociception (1) gig none 0.46   21074052
Heat nociception (1) gig none -0.4   21074052
Heart development and function (1) gig none 1   20371351
Serratia marcescens infection (1) gig none -0.802469135802469   19520911
Serratia marcescens infection (1) gig none -0.755555555555555   19520911
Notch pathway regulation (4) gig Colour defects, bristle morphology defects, notum malformation death, overproliferation sp   19363474
Notch pathway regulation (4) gig Gain of bristles, loss of bristles, bristle morphology defects, notum malformation death, overproliferation, lateral inhibition sp   19363474
Notch pathway regulation (5) gig Bent up (spoon-shaped) wing, wrinkled wings np   19363474
Akt-TOR pathway negative feedback regulation gig Decreased dAkt phosphorylation after insulin stimulation -3.5 10 min insulin stimulation 20585550
Adiposity regulation (1) gig none -0.399   20074523
RTK-Ras-ERK pathway regulation (1) gig none 0.21 0 minutes EGF stimulation 22028469
RTK-Ras-ERK pathway regulation (1) gig none 0.31 10 minutes EGF stimulation 22028469
RTK-Ras-ERK pathway regulation (2) gig none -0.47 30 minutes sSpitz stimulation 22028469
RTK-Ras-ERK pathway regulation (2) gig none -0.8 10 minutes sSpitz stimulation 22028469
Wnt proteins secretion gig none -1.2   22094269

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