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Gene : cnk D. melanogaster

DB identifier  ? FBgn0021818 Secondary Identifier  ? CG6556
Name  ? connector enhancer of ksr Source  FlyBase
  • synonyms:
  • FBgn0063794,
  • CNK,
  • anon-WO0140519.129,
  • FBgn0044753,
  • Connector Enhancer of KSR,
  • FBgn0021818,
  • CG6556,
  • FBan0006556,
  • EK2-3,
  • anon-WO0257455.27,
  • enhancer of KDN,
  • l(2)k16314

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107 Alleles

DB identifier Symbol Allele Class Organism
FBal0180442 cnk[T:Zzzz\FLAG]   Drosophila melanogaster
FBal0257141 cnk[HMS00238]   Drosophila melanogaster
FBal0245368 cnk[HM04070]   Drosophila melanogaster
FBal0180418 cnk[e02017]   Drosophila melanogaster
FBal0155449 cnk[k05916]   Drosophila melanogaster
FBal0159393 cnk[EY06675]   Drosophila melanogaster
FBal0196864 cnk[NT549.MtnA.T:Zzzz\FLAG]   Drosophila melanogaster
FBal0196865 cnk[SAM.L71K.NT.MtnA.T:Zzzz\FLAG]   Drosophila melanogaster
FBal0196866 cnk[CRICmut.NT.MtnA.T:Zzzz\FLAG]   Drosophila melanogaster
FBal0196867 cnk[CT.MtnA.T:Zzzz\FLAG]   Drosophila melanogaster
FBal0196868 cnk[SAMmut-CRICmut.NT.MtnA.T:Zzzz\FLAG]   Drosophila melanogaster
FBal0064057 cnk[k16314]   Drosophila melanogaster
FBal0196869 cnk[RIMmut.NT.MtnA.T:Zzzz\FLAG]   Drosophila melanogaster
FBal0196870 cnk[ISmut.T:Zzzz\FLAG]   Drosophila melanogaster
FBal0196871 cnk[RIMmut.T:Zzzz\FLAG]   Drosophila melanogaster
FBal0196872 cnk[RIMmut.ISmut.T:Zzzz\FLAG]   Drosophila melanogaster
FBal0196873 cnk[SAMmut.T:Zzzz\FLAG]   Drosophila melanogaster
FBal0196874 cnk[CRICmut.T:Zzzz\FLAG]   Drosophila melanogaster
FBal0180431 cnk[E-2337]   Drosophila melanogaster
FBal0093980 cnk[E-1756]   Drosophila melanogaster
FBal0093977 cnk[XE-1040]   Drosophila melanogaster
FBal0180434 cnk[E-1955]   Drosophila melanogaster
FBal0180436 cnk[E-1903]   Drosophila melanogaster
FBal0134117 cnk[dsRNA.cAa]   Drosophila melanogaster
FBal0189612 cnk[EP576]   Drosophila melanogaster
FBal0180433 cnk[E-1993]   Drosophila melanogaster
FBal0093976 cnk[XE-726]   Drosophila melanogaster
FBal0180430 cnk[E-3192]   Drosophila melanogaster
FBal0155450 cnk[dsRNA.cDa]   Drosophila melanogaster
FBal0093979 cnk[E-2083]   Drosophila melanogaster

26 Clones

Secondary Identifier DB identifier
EK290326 FBcl0003318
EK244704 FBcl0003328
EK302632 FBcl0003340
CK01717 FBcl0059741
EK113747 FBcl0140186
EK186914 FBcl0140280
EK302354 FBcl0140416
EK129707 FBcl0140618
LP22576 FBcl0189935
SD22701 FBcl0283596
SD05024 FBcl0283602
SD10193 FBcl0283604
SD09985 FBcl0283606
SD11884 FBcl0283608
SD02381 FBcl0283609
EC051273 FBcl0302250
EC053288 FBcl0302251
EC053756 FBcl0302252
EC056495 FBcl0302253
214479.76 FBcl0478592
12629 FBcl0478596
214503.74 FBcl0478643
274699 FBcl0478665
60728 FBcl0478674
275108 FBcl0478679
DPiM_SD09985 FBcl0739284

4 Exons

DB identifier Symbol
FBgn0021818:3 cnk:3
FBgn0021818:2 cnk:2
FBgn0021818:1 cnk:1
FBgn0021818:4 cnk:4

2 Transcripts

DB identifier Gene
FBtr0086962 cnk
FBtr0340214 cnk

4 UTRs

Class DB identifier
Organism . Name
FivePrimeUTR FBtr0086962-5-prime-utr Drosophila melanogaster
FivePrimeUTR FBtr0340214-5-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0086962-3-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0340214-3-prime-utr Drosophila melanogaster

Interactions

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Other

0 Pathways

2 Cross References

Identifier
Source . Name

Subject . Primary Identifier
36952 NCBI Entrez Gene identifiers FBgn0021818
62646 BioGRID FBgn0021818

11 Data Sets

Name URL
FlyBase data set for Drosophila melanogaster  
TrEMBL data set http://www.ebi.ac.uk/trembl/
Drosophila 12 Genomes Consortium homology  
GenomeRNAi data set  
TreeFam data set  
Panther data set  
IntAct interactions data set  
BioGRID interaction data set http://www.thebiogrid.org/downloads.php
GO Annotation from FlyBase  
FlyBase fasta data set for Drosophila melanogaster  
Drosophila Cell Line and Developmental Stage Gene and Exon Scores  

55 Expression Scores


Gene . Primary Identifier

Submission . Title

Cell Line . Name

Developmental Stage . Name
Score
FBgn0021818 Drosophila Cell Line and Developmental Stage Gene and Exon Scores CME L1 755.0
FBgn0021818 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Sg4 759.0
FBgn0021818 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD11 1104.0
FBgn0021818 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD20-c2 1003.0
FBgn0021818 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD20-c5 820.0
FBgn0021818 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Kc167 588.0
FBgn0021818 Drosophila Cell Line and Developmental Stage Gene and Exon Scores GM2 1095.0
FBgn0021818 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S2-DRSC 1047.0
FBgn0021818 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S2R+ 430.0
FBgn0021818 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S1 1156.0
FBgn0021818 Drosophila Cell Line and Developmental Stage Gene and Exon Scores 1182-4H 1451.0
FBgn0021818 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD16-c3 604.0
FBgn0021818 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD32 1067.0
FBgn0021818 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD17-c3 1081.0
FBgn0021818 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD8 1412.0
FBgn0021818 Drosophila Cell Line and Developmental Stage Gene and Exon Scores CME W1 Cl.8+ 761.0
FBgn0021818 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD9 960.0
FBgn0021818 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmBG1-c1 1366.0
FBgn0021818 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD21 1135.0
FBgn0021818 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD4-c1 842.0
FBgn0021818 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmBG3-c2 1602.0
FBgn0021818 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S3 997.0
FBgn0021818 Drosophila Cell Line and Developmental Stage Gene and Exon Scores CME W2 836.0
FBgn0021818 Drosophila Cell Line and Developmental Stage Gene and Exon Scores mbn2 758.0
FBgn0021818 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmBG2-c2 1578.0
FBgn0021818 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 0-2 h 2094.0
FBgn0021818 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 2-4 h 1973.0
FBgn0021818 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 4-6 h 1955.0
FBgn0021818 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 6-8 h 1717.0
FBgn0021818 Drosophila Cell Line and Developmental Stage Gene and Exon Scores emb 8-10h 1936.0

3 Introns

DB identifier
Organism . Name
intron_FBgn0021818:4_FBgn0021818:2 Drosophila melanogaster
intron_FBgn0021818:2_FBgn0021818:1 Drosophila melanogaster
intron_FBgn0021818:3_FBgn0021818:2 Drosophila melanogaster

18 RNAi Results

Screen Gene Phenotype Score Conditions PubMed ID
Lipid storage cnk none -1.551771333   19067489
Lipid storage cnk none -0.010907443   19067489
ERK signaling cnk ERK activation reduced strong   17086199
Imd pathway regulation cnk Increased Dipt::lacZ protein expression after lipopolysaccharide stimulation 37   15221030
Cell size and cell-cycle regulation (1) cnk none sp   16496002
Muscle morphogenesis and function (1) cnk Flightless np   20220848
PGN-induced dJNK phosphorylation cnk Increased P-JNK protein expression with PGN 5.2 15 min PGN induction 19893628
PGN-induced dJNK phosphorylation cnk Increased P-JNK protein expression with PGN 3.63 60 min PGN induction 19893628
Notch pathway regulation (1) cnk Upregulation of Notch pathway np   20493818
Notch pathway regulation (2) cnk none np C96-GAL4 20493818
Notch pathway regulation (2) cnk Lethal very weak or wing-to-wing variations en-GAL4 20493818
Notch pathway regulation (3) cnk none np   20493818
RTK-Ras-ERK pathway regulation (1) cnk Decreased ERK phosphorylation after EGF stimulation -6.93 10 minutes EGF stimulation 22028469
RTK-Ras-ERK pathway regulation (1) cnk none -0.8 0 minutes EGF stimulation 22028469
RTK-Ras-ERK pathway regulation (2) cnk Decreased ERK phosphorylation after sSpitz and EGF stimulation -7.44 10 minutes sSpitz stimulation 22028469
RTK-Ras-ERK pathway regulation (2) cnk Decreased ERK phosphorylation after sSpitz and EGF stimulation -5.34 30 minutes sSpitz stimulation 22028469
Hippo pathway regulation cnk none -2.24   23263283
Glycosylation regulation (1) cnk none sp   21203496

0 Submissions