Genomics
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15 Alleles
| DB identifier | Symbol | Allele Class | Organism |
|---|---|---|---|
| FBal0257690 | ida[HMS01024] | Drosophila melanogaster | |
| FBal0264940 | ida[PL17] | amorphic allele - genetic evidence | Drosophila melanogaster |
| FBal0046065 | ida[unspecified] | Drosophila melanogaster | |
| FBal0119239 | ida[t63F.dc] | Drosophila melanogaster | |
| FBal0286740 | ida[Scer\UAS.ORF] | Drosophila melanogaster | |
| FBal0286741 | ida[Scer\UAS.ORF.T:Ivir\HA1] | Drosophila melanogaster | |
| FBal0096779 | ida[B4] | amorphic allele - genetic evidence | Drosophila melanogaster |
| FBal0151835 | ida[t63F.K1] | Drosophila melanogaster | |
| FBal0151838 | ida[Delta107] | Drosophila melanogaster | |
| FBal0151836 | ida[dsRNA.cBa] | Drosophila melanogaster | |
| FBal0096778 | ida[D14] | amorphic allele - molecular evidence, amorphic allele - genetic evidence | Drosophila melanogaster |
| FBal0270632 | ida[NIG.10850R] | Drosophila melanogaster | |
| FBal0209723 | ida[GD5998] | Drosophila melanogaster | |
| FBal0265177 | ida[T:Avic\GFP] | Drosophila melanogaster | |
| FBal0231697 | ida[KK102266] | Drosophila melanogaster |
14 Clones
2 UTRs
| Class | DB identifier |
Organism . Name |
|---|---|---|
| FivePrimeUTR | FBtr0073160-5-prime-utr | Drosophila melanogaster |
| ThreePrimeUTR | FBtr0073160-3-prime-utr | Drosophila melanogaster |
Other
53 Pathways
- Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase,
- Senescence-Associated Secretory Phenotype (SASP),
- G2/M DNA damage checkpoint,
- Cellular responses to stress,
- Phosphorylation of the APC/C,
- Cell Cycle,
- Mitotic G1-G1/S phases,
- SCF(Skp2)-mediated degradation of p27/p21,
- S Phase,
- Mitotic G2-G2/M phases,
- Mitotic Anaphase,
- Cyclin E associated events during G1/S transition,
- DNA Replication,
- Autodegradation of Cdh1 by Cdh1:APC/C,
- Separation of Sister Chromatids,
- Cell Cycle, Mitotic,
- Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins,
- DNA Repair,
- APC/C:Cdc20 mediated degradation of Securin,
- Mitotic M-M/G1 phases,
- ATM mediated response to DNA double-strand break,
- Cdc20:Phospho-APC/C mediated degradation of Cyclin A,
- M Phase,
- Homologous recombination repair of replication-independent double-strand breaks,
- APC/C:Cdc20 mediated degradation of Cyclin B,
- G1/S DNA Damage Checkpoints,
- Amplification of signal from the kinetochores,
- APC-Cdc20 mediated degradation of Nek2A,
- Cyclin A/B1 associated events during G2/M transition,
- Regulation of APC/C activators between G1/S and early anaphase,
- Cyclin A:Cdk2-associated events at S phase entry,
- G2/M Checkpoints,
- p53-Independent DNA Damage Response,
- Mitotic Metaphase and Anaphase,
- Polo-like kinase mediated events,
- Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal,
- G2/M DNA replication checkpoint,
- Inactivation of APC/C via direct inhibition of the APC/C complex,
- G2/M Transition,
- Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex,
- Mitotic Spindle Checkpoint,
- p53-Independent G1/S DNA damage checkpoint,
- APC/C:Cdc20 mediated degradation of mitotic proteins,
- Regulation of mitotic cell cycle,
- Double-Strand Break Repair,
- Homologous Recombination Repair,
- APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1,
- Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components,
- G1/S Transition,
- Ubiquitin Mediated Degradation of Phosphorylated Cdc25A,
- Cell Cycle Checkpoints,
- Cellular Senescence,
- APC/C-mediated degradation of cell cycle proteins
1 Cross References
| Identifier |
Source . Name |
Subject . Primary Identifier |
|---|---|---|
| 45574 | NCBI Entrez Gene identifiers | FBgn0041147 |
9 Data Sets
| Name | URL |
|---|---|
| FlyBase data set for Drosophila melanogaster | |
| TrEMBL data set | http://www.ebi.ac.uk/trembl/ |
| Drosophila 12 Genomes Consortium homology | |
| GenomeRNAi data set | |
| TreeFam data set | |
| Panther data set | |
| GO Annotation from FlyBase | |
| FlyBase fasta data set for Drosophila melanogaster | |
| Drosophila Cell Line and Developmental Stage Gene and Exon Scores |
55 Expression Scores
21 RNAi Results
| Screen | Gene | Phenotype | Score | Conditions | PubMed ID |
|---|---|---|---|---|---|
| Lipid storage | ida | none | 0.034862719 | 19067489 | |
| Lipid storage | ida | none | 0.477381406 | 19067489 | |
| ERK signaling | ida | ERK activation increased | weak | 17086199 | |
| Cell size and cell-cycle regulation (1) | ida | none | sp | 16496002 | |
| Muscle morphogenesis and function (1) | ida | none | np | 20220848 | |
| Muscle morphogenesis and function (1) | ida | none | np | 20220848 | |
| Heat nociception (1) | ida | Developmentally lethal | 0 | 21074052 | |
| Heat nociception (1) | ida | none | -1.17 | 21074052 | |
| Heart development and function (1) | ida | none | 1 | 20371351 | |
| Serratia marcescens infection (1) | ida | none | 0.344262295081967 | 19520911 | |
| Notch pathway regulation (4) | ida | Notum malformation death | 7 | 19363474 | |
| Notch pathway regulation (4) | ida | Loss of bristles, bristle morphology defects, notum malformation death | sp | 19363474 | |
| Self-renewal and differentiation in neural stem cells | ida | GFP aggregates number, GFP aggregates size, neuroblast less large cells, neuroblast cell shape, ganglion mother cell shorter lineages, ganglion mother cell shape, neuroblast loss, neuroblast loss with unchanged neuroblast cell size, neuroblast underprolif | sp | 21549331 | |
| Self-renewal and differentiation in neural stem cells | ida | GFP aggregates number, GFP aggregates size, neuroblast smaller cell size, neuroblast less large cells, ganglion mother cell shorter lineages, neuroblast loss, neuroblast loss with smaller neuroblast cell size, neuroblasts smaller, neuroblast underprolifer | sp | 21549331 | |
| Adiposity regulation (1) | ida | none | -0.35 | 20074523 | |
| RTK-Ras-ERK pathway regulation (1) | ida | Increased ERK phosphorylation after EGF stimulation | 2.06 | 0 minutes EGF stimulation | 22028469 |
| RTK-Ras-ERK pathway regulation (1) | ida | none | -0.19 | 10 minutes EGF stimulation | 22028469 |
| RTK-Ras-ERK pathway regulation (2) | ida | none | -0.69 | 10 minutes sSpitz stimulation | 22028469 |
| RTK-Ras-ERK pathway regulation (2) | ida | none | -0.48 | 30 minutes sSpitz stimulation | 22028469 |
| Hippo pathway regulation | ida | none | -1.07 | 23263283 | |
| Glycosylation regulation (1) | ida | none | sp | 21203496 |
