Genomics
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15 Alleles
| DB identifier | Symbol | Allele Class | Organism |
|---|---|---|---|
| FBal0257690 | ida[HMS01024] | Drosophila melanogaster | |
| FBal0264940 | ida[PL17] | amorphic allele - genetic evidence | Drosophila melanogaster |
| FBal0046065 | ida[unspecified] | Drosophila melanogaster | |
| FBal0119239 | ida[t63F.dc] | Drosophila melanogaster | |
| FBal0286740 | ida[Scer\UAS.ORF] | Drosophila melanogaster | |
| FBal0286741 | ida[Scer\UAS.ORF.T:Ivir\HA1] | Drosophila melanogaster | |
| FBal0096779 | ida[B4] | amorphic allele - genetic evidence | Drosophila melanogaster |
| FBal0151835 | ida[t63F.K1] | Drosophila melanogaster | |
| FBal0151838 | ida[Delta107] | Drosophila melanogaster | |
| FBal0151836 | ida[dsRNA.cBa] | Drosophila melanogaster | |
| FBal0096778 | ida[D14] | amorphic allele - molecular evidence, amorphic allele - genetic evidence | Drosophila melanogaster |
| FBal0270632 | ida[NIG.10850R] | Drosophila melanogaster | |
| FBal0209723 | ida[GD5998] | Drosophila melanogaster | |
| FBal0265177 | ida[T:Avic\GFP] | Drosophila melanogaster | |
| FBal0231697 | ida[KK102266] | Drosophila melanogaster |
14 Clones
2 UTRs
| Class | DB identifier |
Organism . Name |
|---|---|---|
| FivePrimeUTR | FBtr0073160-5-prime-utr | Drosophila melanogaster |
| ThreePrimeUTR | FBtr0073160-3-prime-utr | Drosophila melanogaster |
Other
53 Pathways
- APC/C:Cdc20 mediated degradation of Securin,
- SCF(Skp2)-mediated degradation of p27/p21,
- Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins,
- Ubiquitin Mediated Degradation of Phosphorylated Cdc25A,
- Cellular responses to stress,
- Mitotic Anaphase,
- G2/M DNA damage checkpoint,
- Mitotic Spindle Checkpoint,
- Senescence-Associated Secretory Phenotype (SASP),
- p53-Independent G1/S DNA damage checkpoint,
- Mitotic G1-G1/S phases,
- M Phase,
- S Phase,
- Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components,
- Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal,
- G2/M Transition,
- APC/C:Cdc20 mediated degradation of mitotic proteins,
- Cellular Senescence,
- Cyclin A:Cdk2-associated events at S phase entry,
- APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1,
- Inactivation of APC/C via direct inhibition of the APC/C complex,
- DNA Repair,
- Cdc20:Phospho-APC/C mediated degradation of Cyclin A,
- Phosphorylation of the APC/C,
- Cell Cycle,
- Polo-like kinase mediated events,
- Mitotic M-M/G1 phases,
- Regulation of APC/C activators between G1/S and early anaphase,
- Mitotic G2-G2/M phases,
- Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase,
- Homologous recombination repair of replication-independent double-strand breaks,
- G1/S DNA Damage Checkpoints,
- G2/M DNA replication checkpoint,
- Regulation of mitotic cell cycle,
- Cell Cycle, Mitotic,
- Amplification of signal from the kinetochores,
- Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex,
- APC-Cdc20 mediated degradation of Nek2A,
- ATM mediated response to DNA double-strand break,
- Mitotic Metaphase and Anaphase,
- G1/S Transition,
- Homologous Recombination Repair,
- Separation of Sister Chromatids,
- APC/C:Cdc20 mediated degradation of Cyclin B,
- Cyclin A/B1 associated events during G2/M transition,
- APC/C-mediated degradation of cell cycle proteins,
- Cyclin E associated events during G1/S transition,
- Autodegradation of Cdh1 by Cdh1:APC/C,
- G2/M Checkpoints,
- p53-Independent DNA Damage Response,
- DNA Replication,
- Cell Cycle Checkpoints,
- Double-Strand Break Repair
1 Cross References
| Identifier |
Source . Name |
Subject . Primary Identifier |
|---|---|---|
| 45574 | NCBI Entrez Gene identifiers | FBgn0041147 |
9 Data Sets
| Name | URL |
|---|---|
| FlyBase data set for Drosophila melanogaster | |
| TrEMBL data set | http://www.ebi.ac.uk/trembl/ |
| Drosophila 12 Genomes Consortium homology | |
| GenomeRNAi data set | |
| TreeFam data set | |
| Panther data set | |
| GO Annotation from FlyBase | |
| FlyBase fasta data set for Drosophila melanogaster | |
| Drosophila Cell Line and Developmental Stage Gene and Exon Scores |
55 Expression Scores
21 RNAi Results
| Screen | Gene | Phenotype | Score | Conditions | PubMed ID |
|---|---|---|---|---|---|
| Lipid storage | ida | none | 0.034862719 | 19067489 | |
| Lipid storage | ida | none | 0.477381406 | 19067489 | |
| ERK signaling | ida | ERK activation increased | weak | 17086199 | |
| Cell size and cell-cycle regulation (1) | ida | none | sp | 16496002 | |
| Muscle morphogenesis and function (1) | ida | none | np | 20220848 | |
| Muscle morphogenesis and function (1) | ida | none | np | 20220848 | |
| Heat nociception (1) | ida | Developmentally lethal | 0 | 21074052 | |
| Heat nociception (1) | ida | none | -1.17 | 21074052 | |
| Heart development and function (1) | ida | none | 1 | 20371351 | |
| Serratia marcescens infection (1) | ida | none | 0.344262295081967 | 19520911 | |
| Notch pathway regulation (4) | ida | Notum malformation death | 7 | 19363474 | |
| Notch pathway regulation (4) | ida | Loss of bristles, bristle morphology defects, notum malformation death | sp | 19363474 | |
| Self-renewal and differentiation in neural stem cells | ida | GFP aggregates number, GFP aggregates size, neuroblast less large cells, neuroblast cell shape, ganglion mother cell shorter lineages, ganglion mother cell shape, neuroblast loss, neuroblast loss with unchanged neuroblast cell size, neuroblast underprolif | sp | 21549331 | |
| Self-renewal and differentiation in neural stem cells | ida | GFP aggregates number, GFP aggregates size, neuroblast smaller cell size, neuroblast less large cells, ganglion mother cell shorter lineages, neuroblast loss, neuroblast loss with smaller neuroblast cell size, neuroblasts smaller, neuroblast underprolifer | sp | 21549331 | |
| Adiposity regulation (1) | ida | none | -0.35 | 20074523 | |
| RTK-Ras-ERK pathway regulation (1) | ida | Increased ERK phosphorylation after EGF stimulation | 2.06 | 0 minutes EGF stimulation | 22028469 |
| RTK-Ras-ERK pathway regulation (1) | ida | none | -0.19 | 10 minutes EGF stimulation | 22028469 |
| RTK-Ras-ERK pathway regulation (2) | ida | none | -0.69 | 10 minutes sSpitz stimulation | 22028469 |
| RTK-Ras-ERK pathway regulation (2) | ida | none | -0.48 | 30 minutes sSpitz stimulation | 22028469 |
| Hippo pathway regulation | ida | none | -1.07 | 23263283 | |
| Glycosylation regulation (1) | ida | none | sp | 21203496 |
