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Gene : Pka-R1 D. melanogaster

DB identifier  ? FBgn0259243 Secondary Identifier  ? CG42341
Name  ? cAMP-dependent protein kinase R1 Source  FlyBase
  • synonyms:
  • FBgn0037029,
  • CdkR,
  • CG42341,
  • FBgn0000275,
  • PKAi,
  • FBgn0259243,
  • type I regulatory subunit of cAMP-dependent protein kinase,
  • regulatory subunit of protein kinase A,
  • PKA-RI,
  • CG12452,
  • dPKA-RI,
  • FBgn0040635,
  • CG18677,
  • regulatory subunit of PKA,
  • DRI,
  • FBan0012452,
  • RI,
  • PKAR,
  • 18304,
  • cAMP-dependent protein kinase,
  • PKA-R1,
  • protein kinase A,
  • dr[[1]],
  • CG3263,
  • PKA,
  • FBan0003263

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27 Alleles

DB identifier Symbol Allele Class Organism
FBal0281022 Pka-R1[MI06935]   Drosophila melanogaster
FBal0198208 Pka-R1[MB04145]   Drosophila melanogaster
FBal0182253 Pka-R1[f03635]   Drosophila melanogaster
FBal0160012 Pka-R1[c06969]   Drosophila melanogaster
FBal0083277 Pka-R1[7I5]   Drosophila melanogaster
FBal0083278 Pka-R1[11D4]   Drosophila melanogaster
FBal0192723 Pka-R1[EY23145]   Drosophila melanogaster
FBal0160014 Pka-R1[E1] loss of function allele Drosophila melanogaster
FBal0160016 Pka-R1[alphaTub67C.PY]   Drosophila melanogaster
FBal0160015 Pka-R1[18304]   Drosophila melanogaster
FBal0160011 Pka-R1[unspecified]   Drosophila melanogaster
FBal0126506 Pka-R1[Delta.Scer\UAS.T:Ivir\HA1]   Drosophila melanogaster
FBal0126505 Pka-R1[BDK.Scer\UAS.T:Ivir\HA1]   Drosophila melanogaster
FBal0086779 Pka-R1[BDK.Scer\UAS]   Drosophila melanogaster
FBal0086778 Pka-R1[BGD.Scer\UAS]   Drosophila melanogaster
FBal0126504 Pka-R1[GG.Scer\UAS.T:Ivir\HA1]   Drosophila melanogaster
FBal0160013 Pka-R1[Scer\UAS.P\T.cYa]   Drosophila melanogaster
FBal0239305 Pka-R1[JF02605]   Drosophila melanogaster
FBal0195135 Pka-R1[FB-NOF]   Drosophila melanogaster
FBal0208084 Pka-R1[GD11157]   Drosophila melanogaster
FBal0213414 Pka-R1[GD7733]   Drosophila melanogaster
FBal0242370 Pka-R1[JF02788]   Drosophila melanogaster
FBal0242878 Pka-R1[MI00323]   Drosophila melanogaster
FBal0222991 Pka-R1[c07041]   Drosophila melanogaster
FBal0231103 Pka-R1[KK101172]   Drosophila melanogaster
FBal0238424 Pka-R1[KK112823]   Drosophila melanogaster
FBal0273751 Pka-R1[NIG.3263R]   Drosophila melanogaster

76 Clones

Secondary Identifier DB identifier
bs76c12 FBcl0055335
EP03145 FBcl0086195
GH28635 FBcl0124751
GH24529 FBcl0125967
EK197656 FBcl0129448
EK217351 FBcl0129490
EK183322 FBcl0129556
EK241418 FBcl0133430
EK255257 FBcl0134084
EK050207 FBcl0134562
EK291411 FBcl0134848
EK051607 FBcl0134926
EK229935 FBcl0134980
EK086823 FBcl0135012
EK103504 FBcl0135088
EK177433 FBcl0135100
EK228242 FBcl0135114
EK126220 FBcl0135120
EK175160 FBcl0135126
EK172805 FBcl0135156
EK172818 FBcl0135162
EK161954 FBcl0135176
EK061610 FBcl0135182
EK100420 FBcl0135192
EK292214 FBcl0135198
EK158650 FBcl0135204
EK120914 FBcl0135216
EK034729 FBcl0135222
EK193935 FBcl0135238
EK103904 FBcl0135274

19 Exons

DB identifier Symbol
FBgn0259243:8 Pka-R1:8
FBgn0259243:10 Pka-R1:10
FBgn0259243:11 Pka-R1:11
FBgn0259243:12 Pka-R1:12
FBgn0259243:13 Pka-R1:13
FBgn0259243:14 Pka-R1:14
FBgn0259243:18 Pka-R1:18
FBgn0259243:9 Pka-R1:9
FBgn0259243:19 Pka-R1:19
FBgn0259243:7 Pka-R1:7
FBgn0259243:3 Pka-R1:3
FBgn0259243:2 Pka-R1:2
FBgn0259243:4 Pka-R1:4
FBgn0259243:5 Pka-R1:5
FBgn0259243:6 Pka-R1:6
FBgn0259243:16 Pka-R1:16
FBgn0259243:15 Pka-R1:15
FBgn0259243:17 Pka-R1:17
FBgn0259243:1 Pka-R1:1

18 Transcripts

DB identifier Gene
FBtr0302638 Pka-R1
FBtr0300533 Pka-R1
FBtr0300531 Pka-R1
FBtr0302640 Pka-R1
FBtr0302641 Pka-R1
FBtr0300534 Pka-R1
FBtr0302639 Pka-R1
FBtr0300530 Pka-R1
FBtr0299893 Pka-R1
FBtr0299891 Pka-R1
FBtr0300532 Pka-R1
FBtr0302637 Pka-R1
FBtr0302642 Pka-R1
FBtr0300528 Pka-R1
FBtr0302643 Pka-R1
FBtr0300529 Pka-R1
FBtr0299892 Pka-R1
FBtr0300535 Pka-R1

36 UTRs

Class DB identifier
Organism . Name
FivePrimeUTR FBtr0302638-5-prime-utr Drosophila melanogaster
FivePrimeUTR FBtr0302639-5-prime-utr Drosophila melanogaster
FivePrimeUTR FBtr0302640-5-prime-utr Drosophila melanogaster
FivePrimeUTR FBtr0302641-5-prime-utr Drosophila melanogaster
FivePrimeUTR FBtr0302642-5-prime-utr Drosophila melanogaster
FivePrimeUTR FBtr0302643-5-prime-utr Drosophila melanogaster
FivePrimeUTR FBtr0302637-5-prime-utr Drosophila melanogaster
FivePrimeUTR FBtr0299891-5-prime-utr Drosophila melanogaster
FivePrimeUTR FBtr0299892-5-prime-utr Drosophila melanogaster
FivePrimeUTR FBtr0299893-5-prime-utr Drosophila melanogaster
FivePrimeUTR FBtr0300528-5-prime-utr Drosophila melanogaster
FivePrimeUTR FBtr0300529-5-prime-utr Drosophila melanogaster
FivePrimeUTR FBtr0300530-5-prime-utr Drosophila melanogaster
FivePrimeUTR FBtr0300531-5-prime-utr Drosophila melanogaster
FivePrimeUTR FBtr0300532-5-prime-utr Drosophila melanogaster
FivePrimeUTR FBtr0300533-5-prime-utr Drosophila melanogaster
FivePrimeUTR FBtr0300534-5-prime-utr Drosophila melanogaster
FivePrimeUTR FBtr0300535-5-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0302638-3-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0302639-3-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0302640-3-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0302641-3-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0302642-3-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0302643-3-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0302637-3-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0299891-3-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0299892-3-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0299893-3-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0300528-3-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0300529-3-prime-utr Drosophila melanogaster

Interactions

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2 Cross References

Identifier
Source . Name

Subject . Primary Identifier
40305 NCBI Entrez Gene identifiers FBgn0259243
65562 BioGRID FBgn0259243

11 Data Sets

Name URL
FlyBase data set for Drosophila melanogaster  
Swiss-Prot data set http://ca.expasy.org/sprot
Drosophila 12 Genomes Consortium homology  
GenomeRNAi data set  
TreeFam data set  
Panther data set  
IntAct interactions data set  
BioGRID interaction data set http://www.thebiogrid.org/downloads.php
GO Annotation from FlyBase  
FlyBase fasta data set for Drosophila melanogaster  
Drosophila Cell Line and Developmental Stage Gene and Exon Scores  

55 Expression Scores


Gene . Primary Identifier

Submission . Title

Cell Line . Name

Developmental Stage . Name
Score
FBgn0259243 Drosophila Cell Line and Developmental Stage Gene and Exon Scores CME L1 1693.0
FBgn0259243 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Sg4 1125.0
FBgn0259243 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD11 796.0
FBgn0259243 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD20-c2 1253.0
FBgn0259243 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD20-c5 1137.0
FBgn0259243 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Kc167 797.0
FBgn0259243 Drosophila Cell Line and Developmental Stage Gene and Exon Scores GM2 881.0
FBgn0259243 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S2-DRSC 547.0
FBgn0259243 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S2R+ 467.0
FBgn0259243 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S1 907.0
FBgn0259243 Drosophila Cell Line and Developmental Stage Gene and Exon Scores 1182-4H 1227.0
FBgn0259243 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD16-c3 794.0
FBgn0259243 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD32 872.0
FBgn0259243 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD17-c3 876.0
FBgn0259243 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD8 824.0
FBgn0259243 Drosophila Cell Line and Developmental Stage Gene and Exon Scores CME W1 Cl.8+ 1179.0
FBgn0259243 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD9 826.0
FBgn0259243 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmBG1-c1 864.0
FBgn0259243 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD21 1354.0
FBgn0259243 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD4-c1 854.0
FBgn0259243 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmBG3-c2 1369.0
FBgn0259243 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S3 1124.0
FBgn0259243 Drosophila Cell Line and Developmental Stage Gene and Exon Scores CME W2 456.0
FBgn0259243 Drosophila Cell Line and Developmental Stage Gene and Exon Scores mbn2 835.0
FBgn0259243 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmBG2-c2 745.0
FBgn0259243 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 0-2 h 3541.0
FBgn0259243 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 2-4 h 1635.0
FBgn0259243 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 4-6 h 742.0
FBgn0259243 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 6-8 h 771.0
FBgn0259243 Drosophila Cell Line and Developmental Stage Gene and Exon Scores emb 8-10h 1107.0

21 Introns

DB identifier
Organism . Name
intron_FBgn0259243:10_FBgn0259243:11 Drosophila melanogaster
intron_FBgn0259243:11_FBgn0259243:12 Drosophila melanogaster
intron_FBgn0259243:12_FBgn0259243:13 Drosophila melanogaster
intron_FBgn0259243:13_FBgn0259243:14 Drosophila melanogaster
intron_FBgn0259243:14_FBgn0259243:18 Drosophila melanogaster
intron_FBgn0259243:13_FBgn0259243:15 Drosophila melanogaster
intron_FBgn0259243:15_FBgn0259243:18 Drosophila melanogaster
intron_FBgn0259243:9_FBgn0259243:12 Drosophila melanogaster
intron_FBgn0259243:15_FBgn0259243:19 Drosophila melanogaster
intron_FBgn0259243:7_FBgn0259243:12 Drosophila melanogaster
intron_FBgn0259243:8_FBgn0259243:12 Drosophila melanogaster
intron_FBgn0259243:6_FBgn0259243:12 Drosophila melanogaster
intron_FBgn0259243:14_FBgn0259243:16 Drosophila melanogaster
intron_FBgn0259243:14_FBgn0259243:19 Drosophila melanogaster
intron_FBgn0259243:3_FBgn0259243:12 Drosophila melanogaster
intron_FBgn0259243:15_FBgn0259243:17 Drosophila melanogaster
intron_FBgn0259243:2_FBgn0259243:4 Drosophila melanogaster
intron_FBgn0259243:4_FBgn0259243:12 Drosophila melanogaster
intron_FBgn0259243:2_FBgn0259243:5 Drosophila melanogaster
intron_FBgn0259243:5_FBgn0259243:12 Drosophila melanogaster
intron_FBgn0259243:1_FBgn0259243:4 Drosophila melanogaster

24 RNAi Results

Screen Gene Phenotype Score Conditions PubMed ID
Lipid storage Pka-R1 Decreased lipid droplet area -1.841696622   19067489
Lipid storage Pka-R1 Decreased lipid droplet area -0.16507255   19067489
Lipid storage Pka-R1 Decreased lipid droplet area -1.789001145   19067489
Lipid storage Pka-R1 none -1.656197953   19067489
Lipid storage Pka-R1 none -1.318198788   19067489
Lipid storage Pka-R1 none -2.796059607   19067489
ERK signaling Pka-R1 ERK activation reduced strong   17086199
Cell size and cell-cycle regulation (1) Pka-R1 none sp   16496002
Cell size and cell-cycle regulation (1) Pka-R1 none sp   16496002
Muscle morphogenesis and function (1) Pka-R1 none np   20220848
Muscle morphogenesis and function (1) Pka-R1 none np   20220848
Heat nociception (1) Pka-R1 none -1.17   21074052
Serratia marcescens infection (1) Pka-R1 Decreased viability after Serratia marcescens infection -1.74468085106382   19520911
Notch pathway regulation (4) Pka-R1 none 0   19363474
Notch pathway regulation (4) Pka-R1 none 0   19363474
PGN-induced dJNK phosphorylation Pka-R1 Increased P-JNK protein expression with PGN 1.98 60 min PGN induction 19893628
Adiposity regulation (1) Pka-R1 none -0.169   20074523
Vaccinia virus infection Pka-R1 none sp   20585561
RTK-Ras-ERK pathway regulation (1) Pka-R1 Decreased ERK phosphorylation after EGF stimulation -3 10 minutes EGF stimulation 22028469
RTK-Ras-ERK pathway regulation (1) Pka-R1 none -1 0 minutes EGF stimulation 22028469
RTK-Ras-ERK pathway regulation (2) Pka-R1 none -0.43 30 minutes sSpitz stimulation 22028469
RTK-Ras-ERK pathway regulation (2) Pka-R1 none -0.38 10 minutes sSpitz stimulation 22028469
Hippo pathway regulation Pka-R1 none -1.71   23263283
Glycosylation regulation (1) Pka-R1 none sp   21203496

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