Genomics
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109 Alleles
38 Clones
16 Exons
| DB identifier | Symbol |
|---|---|
| FBgn0003256:2 | rl:2 |
| FBgn0003256:5 | rl:5 |
| FBgn0003256:7 | rl:7 |
| FBgn0003256:9 | rl:9 |
| FBgn0003256:11 | rl:11 |
| FBgn0003256:12 | rl:12 |
| FBgn0003256:13 | rl:13 |
| FBgn0003256:14 | rl:14 |
| FBgn0003256:3 | rl:3 |
| FBgn0003256:10 | rl:10 |
| FBgn0003256:1 | rl:1 |
| FBgn0003256:4 | rl:4 |
| FBgn0003256:6 | rl:6 |
| FBgn0003256:15 | rl:15 |
| FBgn0003256:8 | rl:8 |
| FBgn0003256:16 | rl:16 |
6 Transcripts
| DB identifier | Gene |
|---|---|
| FBtr0113703 | rl |
| FBtr0329920 | rl |
| FBtr0329919 | rl |
| FBtr0113700 | rl |
| FBtr0113702 | rl |
| FBtr0113701 | rl |
12 UTRs
| Class | DB identifier |
Organism . Name |
|---|---|---|
| FivePrimeUTR | FBtr0113700-5-prime-utr | Drosophila melanogaster |
| FivePrimeUTR | FBtr0113701-5-prime-utr | Drosophila melanogaster |
| FivePrimeUTR | FBtr0113702-5-prime-utr | Drosophila melanogaster |
| FivePrimeUTR | FBtr0113703-5-prime-utr | Drosophila melanogaster |
| FivePrimeUTR | FBtr0329919-5-prime-utr | Drosophila melanogaster |
| FivePrimeUTR | FBtr0329920-5-prime-utr | Drosophila melanogaster |
| ThreePrimeUTR | FBtr0113700-3-prime-utr | Drosophila melanogaster |
| ThreePrimeUTR | FBtr0113701-3-prime-utr | Drosophila melanogaster |
| ThreePrimeUTR | FBtr0113702-3-prime-utr | Drosophila melanogaster |
| ThreePrimeUTR | FBtr0113703-3-prime-utr | Drosophila melanogaster |
| ThreePrimeUTR | FBtr0329919-3-prime-utr | Drosophila melanogaster |
| ThreePrimeUTR | FBtr0329920-3-prime-utr | Drosophila melanogaster |
Other
115 Pathways
- MyD88 cascade initiated on plasma membrane,
- Activation of NMDA receptor upon glutamate binding and postsynaptic events,
- Signal attenuation,
- Nuclear Events (kinase and transcription factor activation),
- GRB2 events in ERBB2 signaling,
- Signal transduction by L1,
- Mitotic G2-G2/M phases,
- DAP12 signaling,
- Senescence-Associated Secretory Phenotype (SASP),
- Toll Like Receptor 10 (TLR10) Cascade,
- DAP12 interactions,
- SOS-mediated signalling,
- Cytokine Signaling in Immune system,
- DNA Replication,
- Cellular responses to stress,
- Signaling by EGFR,
- Toll Like Receptor TLR1:TLR2 Cascade,
- SHC-related events,
- RAF phosphorylates MEK,
- Frs2-mediated activation,
- SHC1 events in ERBB2 signaling,
- IRS-related events triggered by IGF1R,
- Toll Like Receptor 5 (TLR5) Cascade,
- IRS-mediated signalling,
- Signaling by ERBB2,
- Signaling by PDGF,
- Signaling by Interleukins,
- TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation,
- Oxidative Stress Induced Senescence,
- Activation of the AP-1 family of transcription factors,
- ARMS-mediated activation,
- M Phase,
- FCERI mediated MAPK activation,
- ERK/MAPK targets,
- IGF1R signaling cascade,
- MAPK targets/ Nuclear events mediated by MAP kinases,
- Cell Cycle,
- Toll Like Receptor 3 (TLR3) Cascade,
- Fcgamma receptor (FCGR) dependent phagocytosis,
- Mitotic M-M/G1 phases,
- Insulin receptor recycling,
- MyD88 dependent cascade initiated on endosome,
- Spry regulation of FGF signaling,
- Cellular Senescence,
- IRS-related events,
- Negative regulation of FGFR signaling,
- Innate Immune System,
- Immune System,
- Signaling by Leptin,
- Signaling by FGFR,
- ERK activation,
- NGF signalling via TRKA from the plasma membrane,
- Downstream signaling of activated FGFR,
- Toll Like Receptor 4 (TLR4) Cascade,
- Disease,
- Oncogene Induced Senescence,
- Signaling Pathways,
- Fc epsilon receptor (FCERI) signaling,
- DINR-mediated activation,
- Toll Like Receptor 2 (TLR2) Cascade,
- Toll Like Receptor 9 (TLR9) Cascade,
- MAP kinase activation in TLR cascade,
- Gastrin-CREB signalling pathway via PKC and MAPK,
- Developmental Biology,
- Activated TLR4 signalling,
- MyD88:Mal cascade initiated on plasma membrane,
- Neurotransmitter Receptor Binding And Downstream Transmission In The Postsynaptic Cell,
- Signaling by GPCR,
- Downstream signal transduction,
- MyD88-independent cascade,
- Toll-Like Receptors Cascades,
- L1CAM interactions,
- Toll Like Receptor TLR6:TLR2 Cascade,
- Transmission across Chemical Synapses,
- Signalling to ERKs,
- Interleukin-2 signaling,
- TRAF6 Mediated Induction of proinflammatory cytokines,
- Insulin signaling pathway,
- MEK activation,
- Regulation of actin dynamics for phagocytic cup formation,
- Signaling by FGFR in disease,
- Golgi Cisternae Pericentriolar Stack Reorganization,
- Signaling by SCF-KIT,
- Mitotic Prophase,
- Toll Like Receptor 7/8 (TLR7/8) Cascade,
- SHC-related events triggered by IGF1R,
- Axon guidance,
- Signalling to p38 via RIT and RIN,
- RAF/MAP kinase cascade,
- SHC1 events in EGFR signaling,
- Post NMDA receptor activation events,
- Cell Cycle, Mitotic,
- ERK1 activation,
- Insulin receptor mediated signaling,
- Signalling to RAS,
- ERKs are inactivated,
- Recycling pathway of L1,
- Signaling by ERBB4,
- NCAM signaling for neurite out-growth,
- RSK activation,
- RAF activation,
- FRS2-mediated cascade,
- TRIF-mediated TLR3/TLR4 signaling,
- Mitotic G1-G1/S phases,
- Signaling by EGFR in Cancer,
- Signaling by NGF,
- SHC-mediated signalling,
- CREB phosphorylation through the activation of Ras,
- Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R),
- Insulin receptor signalling cascade,
- Prolonged ERK activation events,
- Neuronal System,
- GRB2 events in EGFR signaling,
- ERK2 activation,
- SHC1 events in ERBB4 signaling
2 Cross References
| Identifier |
Source . Name |
Subject . Primary Identifier |
|---|---|---|
| 3354888 | NCBI Entrez Gene identifiers | FBgn0003256 |
| 78013 | BioGRID | FBgn0003256 |
11 Data Sets
| Name | URL |
|---|---|
| FlyBase data set for Drosophila melanogaster | |
| Swiss-Prot data set | http://ca.expasy.org/sprot |
| Drosophila 12 Genomes Consortium homology | |
| GenomeRNAi data set | |
| TreeFam data set | |
| Panther data set | |
| IntAct interactions data set | |
| BioGRID interaction data set | http://www.thebiogrid.org/downloads.php |
| GO Annotation from FlyBase | |
| FlyBase fasta data set for Drosophila melanogaster | |
| Drosophila Cell Line and Developmental Stage Gene and Exon Scores |
55 Expression Scores
18 Introns
39 RNAi Results
| Screen | Gene | Phenotype | Score | Conditions | PubMed ID |
|---|---|---|---|---|---|
| Cell size regulation | rl | Decreased cell size | -2.8 | 19216764 | |
| Lipid storage | rl | none | -0.109576156 | 19067489 | |
| Lipid storage | rl | none | 0.238725039 | 19067489 | |
| Lipid storage | rl | none | 0.11819402 | 19067489 | |
| Lipid storage | rl | none | -1.711016499 | 19067489 | |
| Neural outgrowth | rl | Defasciculation | np | 18604272 | |
| Cell cycle regulation (1) | rl | none | np | 15616552 | |
| Cell cycle regulation (2) | rl | none | np | 15616552 | |
| Cell size and cell-cycle regulation (1) | rl | none | sp | 16496002 | |
| Cell size and cell-cycle regulation (1) | rl | none | sp | 16496002 | |
| Combinatorial effect with methyl methanesulphonate (2) | rl | Synthetic lethal with methyl methanesulphonate | sp | 19543366 | |
| Muscle morphogenesis and function (1) | rl | Lethal | np | 20220848 | |
| Muscle morphogenesis and function (1) | rl | Lethal | np | 20220848 | |
| Muscle morphogenesis and function (1) | rl | Lethal | np | 20220848 | |
| Muscle morphogenesis and function (1) | rl | Lethal | np | 20220848 | |
| Muscle morphogenesis and function (1) | rl | none | np | 20220848 | |
| Heat nociception (1) | rl | Lethal | 0 | 21074052 | |
| Heat nociception (1) | rl | none | 1.31 | 21074052 | |
| Heat nociception (1) | rl | none | 1.65 | 21074052 | |
| Heart development and function (1) | rl | none | 1 | 20371351 | |
| Heart development and function (1) | rl | none | 1 | 20371351 | |
| Notch pathway regulation (4) | rl | Notum malformation death | 7 | 19363474 | |
| Notch pathway regulation (4) | rl | Bristle morphology defects, notum malformation death | sp | 19363474 | |
| Notch pathway regulation (4) | rl | Bristle morphology defects, notum malformation death | sp | 19363474 | |
| Notch pathway regulation (4) | rl | Bristle morphology defects, notum malformation death | sp | 19363474 | |
| PGN-induced dJNK phosphorylation | rl | Increased P-JNK protein expression with PGN | 2.5 | 15 min PGN induction | 19893628 |
| Pol II elongation | rl | none | 75 | 20 min heat shock | 19279664 |
| Actin organization and cell morphology (1) | rl | none | np | 19265526 | |
| Actin organization and cell morphology (2) | rl | none | np | 19265526 | |
| Actin organization and cell morphology (3) | rl | none | np | 19265526 |
