Genomics
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Regulatory Regions Displayer
34 Alleles
82 Clones
7 Exons
| DB identifier | Symbol |
|---|---|
| FBgn0041191:2 | Rheb:2 |
| FBgn0041191:4 | Rheb:4 |
| FBgn0041191:5 | Rheb:5 |
| FBgn0041191:6 | Rheb:6 |
| FBgn0041191:7 | Rheb:7 |
| FBgn0041191:1 | Rheb:1 |
| FBgn0041191:3 | Rheb:3 |
4 UTRs
| Class | DB identifier |
Organism . Name |
|---|---|---|
| FivePrimeUTR | FBtr0078693-5-prime-utr | Drosophila melanogaster |
| FivePrimeUTR | FBtr0078694-5-prime-utr | Drosophila melanogaster |
| ThreePrimeUTR | FBtr0078693-3-prime-utr | Drosophila melanogaster |
| ThreePrimeUTR | FBtr0078694-3-prime-utr | Drosophila melanogaster |
Other
21 Pathways
- Insulin receptor recycling,
- IRS-mediated signalling,
- Release of eIF4E,
- Regulation of AMPK activity via LKB1,
- TOR signaling pathway,
- Signaling Pathways,
- PI3K Cascade,
- Insulin receptor signalling cascade,
- mTOR signalling,
- DINR-mediated activation,
- mTORC1-mediated signalling,
- IRS-related events triggered by IGF1R,
- Regulation of Rheb GTPase activity by AMPK,
- Insulin signaling pathway,
- Energy dependent regulation of mTOR by LKB1-AMPK,
- IRS-related events,
- Insulin receptor mediated signaling,
- Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R),
- IGF1R signaling cascade,
- IRS activation,
- PKB-mediated events
1 Cross References
| Identifier |
Source . Name |
Subject . Primary Identifier |
|---|---|---|
| 117332 | NCBI Entrez Gene identifiers | FBgn0041191 |
10 Data Sets
| Name | URL |
|---|---|
| FlyBase data set for Drosophila melanogaster | |
| Swiss-Prot data set | http://ca.expasy.org/sprot |
| Drosophila 12 Genomes Consortium homology | |
| GenomeRNAi data set | |
| TreeFam data set | |
| Panther data set | |
| IntAct interactions data set | |
| GO Annotation from FlyBase | |
| FlyBase fasta data set for Drosophila melanogaster | |
| Drosophila Cell Line and Developmental Stage Gene and Exon Scores |
55 Expression Scores
6 Introns
20 RNAi Results
| Screen | Gene | Phenotype | Score | Conditions | PubMed ID |
|---|---|---|---|---|---|
| Cell size regulation | Rheb | Decreased cell size | -2.52 | 19216764 | |
| Lipid storage | Rheb | none | 1.777877965 | 19067489 | |
| Lipid storage | Rheb | none | 3.660486112 | 19067489 | |
| Neural outgrowth | Rheb | Defasciculation | np | 18604272 | |
| ERK signaling | Rheb | ERK activation increased | strong | 17086199 | |
| Constitutive protein secretion and Golgi organization (1) | Rheb | Decreased horseradish peroxidase protein expression | sp | 16452979 | |
| Cell size and cell-cycle regulation (1) | Rheb | none | sp | 16496002 | |
| Mitosis | Rheb | Chromosome misalignment | np | 17412918 | |
| Combinatorial effect with methyl methanesulphonate (2) | Rheb | none | sp | 19543366 | |
| Mutant human huntingtin aggregation | Rheb | Decreased mutant human huntingtin aggregation | <= -2 | 19789644 | |
| Akt-TOR pathway negative feedback regulation | Rheb | Increased dAkt phosphorylation | 3.2 | without insulin stimulation | 20585550 |
| Akt-TOR pathway negative feedback regulation | Rheb | none | 2.1 | 10 min insulin stimulation | 20585550 |
| S2 cell spreading | Rheb | none | np | 21041442 | |
| RTK-Ras-ERK pathway regulation (1) | Rheb | none | -1.34 | 0 minutes EGF stimulation | 22028469 |
| RTK-Ras-ERK pathway regulation (1) | Rheb | none | 0.37 | 10 minutes EGF stimulation | 22028469 |
| RTK-Ras-ERK pathway regulation (2) | Rheb | none | 0.55 | 30 minutes sSpitz stimulation | 22028469 |
| RTK-Ras-ERK pathway regulation (2) | Rheb | none | 0.98 | 10 minutes sSpitz stimulation | 22028469 |
| Wg pathway regulation (1) | Rheb | Decreased WgRluc and not changed sFluc protein expression | medium | 21886182 | |
| Hippo pathway regulation | Rheb | none | 0.62 | 23263283 | |
| Glycosylation regulation (1) | Rheb | none | sp | 21203496 |
