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Gene : Psn D. melanogaster

DB identifier  ? FBgn0019947 Secondary Identifier  ? CG18803
Name  ? Presenilin Source  FlyBase
  • synonyms:
  • Dpresenilin,
  • DrosPS,
  • FBgn0042202,
  • pres,
  • DPsn,
  • presenilin,
  • DmPS,
  • FBgn0019947,
  • l(3)77CDb,
  • pre-senelin,
  • CG5868,
  • FBan0018803,
  • CG18803,
  • unnamed,
  • PS1,
  • DPS,
  • PS,
  • PSN

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119 Alleles

DB identifier Symbol Allele Class Organism
FBal0220858 Psn[G4133]   Drosophila melanogaster
FBal0281092 Psn[dsRNA.Scer\UAS.cBa]   Drosophila melanogaster
FBal0243921 Psn[Scer\UAS.T:Hsap\MYC]   Drosophila melanogaster
FBal0196088 Psn[PIE-11]   Drosophila melanogaster
FBal0196084 Psn[DIE-2]   Drosophila melanogaster
FBal0196085 Psn[MIE-5]   Drosophila melanogaster
FBal0196086 Psn[MIE-12]   Drosophila melanogaster
FBal0196087 Psn[MIE-15]   Drosophila melanogaster
FBal0196089 Psn[SIE-5]   Drosophila melanogaster
FBal0217495 Psn[miRNA.CDS.Scer\UAS]   Drosophila melanogaster
FBal0217496 Psn[GMR.PG]   Drosophila melanogaster
FBal0217497 Psn[D257A.GMR]   Drosophila melanogaster
FBal0277771 Psn[VDRC.cUa]   Drosophila melanogaster
FBal0244413 Psn[D278A.GMR]   Drosophila melanogaster
FBal0130809 Psn[dsRNA.cLb]   Drosophila melanogaster
FBal0095650 Psn[alphaTub84B.PS]   Drosophila melanogaster
FBal0097194 Psn[Psn.7] loss of function allele Drosophila melanogaster
FBal0097199 Psn[+t9]   Drosophila melanogaster
FBal0097200 Psn[+t6]   Drosophila melanogaster
FBal0097201 Psn[+t3.7]   Drosophila melanogaster
FBal0097202 Psn[+t12]   Drosophila melanogaster
FBal0102919 Psn[t.6]   Drosophila melanogaster
FBal0102920 Psn[hs.PG]   Drosophila melanogaster
FBal0152290 Psn[dsRNA.cIa]   Drosophila melanogaster
FBal0156028 Psn[527.sev]   Drosophila melanogaster
FBal0156030 Psn[527.deltaE9.GMR]   Drosophila melanogaster
FBal0156032 Psn[527.deltaE9.D447A.GMR]   Drosophila melanogaster
FBal0156034 Psn[527.GMR]   Drosophila melanogaster
FBal0156036 Psn[527.D447A.GMR]   Drosophila melanogaster
FBal0156037 Psn[527.D279A.GMR]   Drosophila melanogaster

113 Clones

Secondary Identifier DB identifier
ESG017c.B21_E11 FBcl0004901
AT23312 FBcl0015089
AT24545 FBcl0032971
AT26032 FBcl0032999
AT28676 FBcl0033001
AT20603 FBcl0033009
AT29922 FBcl0033027
AT05081 FBcl0033031
AT29910 FBcl0033047
bs49h11 FBcl0054819
EC26920 FBcl0069951
EN03823 FBcl0099125
GH23656 FBcl0109137
GH10727 FBcl0109141
EK261462 FBcl0135440
EK266162 FBcl0136324
EK299660 FBcl0136522
EK118625 FBcl0136532
EK116101 FBcl0136536
EK298101 FBcl0136616
EK248937 FBcl0136714
EK157656 FBcl0136728
GM08632 FBcl0142600
LD02289 FBcl0153089
LD16349 FBcl0153092
LD05058 FBcl0153098
LD09473 FBcl0153102
LD06652 FBcl0153105
LD05588 FBcl0153141
LD15068 FBcl0153142

14 Exons

DB identifier Symbol
FBgn0019947:1 Psn:1
FBgn0019947:4 Psn:4
FBgn0019947:6 Psn:6
FBgn0019947:7 Psn:7
FBgn0019947:8 Psn:8
FBgn0019947:9 Psn:9
FBgn0019947:12 Psn:12
FBgn0019947:13 Psn:13
FBgn0019947:14 Psn:14
FBgn0019947:2 Psn:2
FBgn0019947:5 Psn:5
FBgn0019947:11 Psn:11
FBgn0019947:3 Psn:3
FBgn0019947:10 Psn:10

5 Transcripts

DB identifier Gene
FBtr0078192 Psn
FBtr0114517 Psn
FBtr0333478 Psn
FBtr0333479 Psn
FBtr0078193 Psn

10 UTRs

Class DB identifier
Organism . Name
FivePrimeUTR FBtr0078192-5-prime-utr Drosophila melanogaster
FivePrimeUTR FBtr0078193-5-prime-utr Drosophila melanogaster
FivePrimeUTR FBtr0114517-5-prime-utr Drosophila melanogaster
FivePrimeUTR FBtr0333478-5-prime-utr Drosophila melanogaster
FivePrimeUTR FBtr0333479-5-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0078192-3-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0078193-3-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0114517-3-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0333478-3-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0333479-3-prime-utr Drosophila melanogaster

Interactions

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2 Cross References

Identifier
Source . Name

Subject . Primary Identifier
40260 NCBI Entrez Gene identifiers FBgn0019947
65518 BioGRID FBgn0019947

11 Data Sets

Name URL
FlyBase data set for Drosophila melanogaster  
Swiss-Prot data set http://ca.expasy.org/sprot
Drosophila 12 Genomes Consortium homology  
GenomeRNAi data set  
TreeFam data set  
Panther data set  
IntAct interactions data set  
BioGRID interaction data set http://www.thebiogrid.org/downloads.php
GO Annotation from FlyBase  
FlyBase fasta data set for Drosophila melanogaster  
Drosophila Cell Line and Developmental Stage Gene and Exon Scores  

55 Expression Scores


Gene . Primary Identifier

Submission . Title

Cell Line . Name

Developmental Stage . Name
Score
FBgn0019947 Drosophila Cell Line and Developmental Stage Gene and Exon Scores CME L1 3750.0
FBgn0019947 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Sg4 3311.0
FBgn0019947 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD11 2388.0
FBgn0019947 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD20-c2 2947.0
FBgn0019947 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD20-c5 3742.0
FBgn0019947 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Kc167 1629.0
FBgn0019947 Drosophila Cell Line and Developmental Stage Gene and Exon Scores GM2 2741.0
FBgn0019947 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S2-DRSC 2776.0
FBgn0019947 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S2R+ 2960.0
FBgn0019947 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S1 2382.0
FBgn0019947 Drosophila Cell Line and Developmental Stage Gene and Exon Scores 1182-4H 2694.0
FBgn0019947 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD16-c3 1970.0
FBgn0019947 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD32 1944.0
FBgn0019947 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD17-c3 2527.0
FBgn0019947 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD8 2344.0
FBgn0019947 Drosophila Cell Line and Developmental Stage Gene and Exon Scores CME W1 Cl.8+ 2497.0
FBgn0019947 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD9 3010.0
FBgn0019947 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmBG1-c1 1636.0
FBgn0019947 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD21 2965.0
FBgn0019947 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD4-c1 2172.0
FBgn0019947 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmBG3-c2 4386.0
FBgn0019947 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S3 3062.0
FBgn0019947 Drosophila Cell Line and Developmental Stage Gene and Exon Scores CME W2 2182.0
FBgn0019947 Drosophila Cell Line and Developmental Stage Gene and Exon Scores mbn2 2264.0
FBgn0019947 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmBG2-c2 1409.0
FBgn0019947 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 0-2 h 3009.0
FBgn0019947 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 2-4 h 3541.0
FBgn0019947 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 4-6 h 3899.0
FBgn0019947 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 6-8 h 2828.0
FBgn0019947 Drosophila Cell Line and Developmental Stage Gene and Exon Scores emb 8-10h 2879.0

16 Introns

DB identifier
Organism . Name
intron_FBgn0019947:1_FBgn0019947:4 Drosophila melanogaster
intron_FBgn0019947:4_FBgn0019947:6 Drosophila melanogaster
intron_FBgn0019947:6_FBgn0019947:7 Drosophila melanogaster
intron_FBgn0019947:7_FBgn0019947:8 Drosophila melanogaster
intron_FBgn0019947:8_FBgn0019947:9 Drosophila melanogaster
intron_FBgn0019947:9_FBgn0019947:12 Drosophila melanogaster
intron_FBgn0019947:12_FBgn0019947:13 Drosophila melanogaster
intron_FBgn0019947:13_FBgn0019947:14 Drosophila melanogaster
intron_FBgn0019947:3_FBgn0019947:4 Drosophila melanogaster
intron_FBgn0019947:9_FBgn0019947:10 Drosophila melanogaster
intron_FBgn0019947:10_FBgn0019947:13 Drosophila melanogaster
intron_FBgn0019947:2_FBgn0019947:5 Drosophila melanogaster
intron_FBgn0019947:5_FBgn0019947:6 Drosophila melanogaster
intron_FBgn0019947:9_FBgn0019947:11 Drosophila melanogaster
intron_FBgn0019947:11_FBgn0019947:13 Drosophila melanogaster
intron_FBgn0019947:2_FBgn0019947:4 Drosophila melanogaster

31 RNAi Results

Screen Gene Phenotype Score Conditions PubMed ID
Lipid storage Psn none 0.042284419   19067489
Lipid storage Psn none -0.592661763   19067489
Cell size and cell-cycle regulation (1) Psn none sp   16496002
Store-operated calcium influx regulation Psn none np   15866891
Combinatorial effect with methyl methanesulphonate (2) Psn none sp   19543366
Muscle morphogenesis and function (1) Psn none np   20220848
Muscle morphogenesis and function (1) Psn none np   20220848
Heat nociception (1) Psn none 0.59   21074052
Heart development and function (1) Psn none 1   20371351
Heart development and function (2) Psn none 2.09   20371351
Serratia marcescens infection (1) Psn none -0.682926829268292   19520911
Notch pathway regulation (1) Psn none no phenotype temperature: 18 19363474
Notch pathway regulation (1) Psn none no phenotype temperature: 25 19363474
Notch pathway regulation (1) Psn Adults die in food lethal temperature: 29 19363474
Notch pathway regulation (2) Psn Lethal lethal temperature: 29 19363474
Notch pathway regulation (2) Psn Loss of m rare, weak temperature: 18 19363474
Notch pathway regulation (2) Psn Strong loss of bristles, m only medium to strong temperature: 25 19363474
Notch pathway regulation (3) Psn Stronger loss of bristles, rare duplication of hairs medium to strong temperature: 18 19363474
Notch pathway regulation (3) Psn Strong loss of bristles medium to strong temperature: 25 19363474
Notch pathway regulation (3) Psn Strong loss of bristles medium to strong temperature: 29 19363474
Notch pathway regulation (4) Psn Loss of bristles, empty or multiple sockets, notum malformation death, lateral inhibition sp   19363474
Notch pathway regulation (4) Psn Loss of bristles, notum malformation death sp   19363474
Notch pathway regulation (5) Psn Broad delta-like veins, bent up (spoon-shaped) wing np   19363474
Notch pathway regulation (6) Psn none np   19363474
Notch pathway regulation (7) Psn Too many sensory organ precursor cells np   19363474
Notch pathway regulation (1) Psn Downregulation of Notch pathway np   20493818
Notch pathway regulation (2) Psn Downregulation of Notch pathway; adult wing veins: broader, deltas; adult wing posterior compartment: blister; wing disc NRE:EGFP: down; wing disc myrRFP: reduced; lethal sp en-GAL4 20493818
Notch pathway regulation (2) Psn Lethal strong en-GAL4 20493818
Adiposity regulation (1) Psn none -0.524   20074523
Hippo pathway regulation Psn none 0.33   23263283

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