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Gene : Not1 D. melanogaster

DB identifier  ? FBgn0085436 Secondary Identifier  ? CG34407
Name  ? Not1 Source  FlyBase
  • synonyms:
  • FBgn0033424,
  • FBgn0026000,
  • unnamed,
  • FBgn0085436,
  • FBan0001884,
  • FBan0001874,
  • FBgn0033425,
  • FBgn0062162,
  • CG1884,
  • anon-EST:Liang-1.29,
  • CG34407,
  • NOT1,
  • clone 1.29,
  • CG1874,
  • anon-WO0118547.221,
  • NOT

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14 Alleles

DB identifier Symbol Allele Class Organism
FBal0220888 Not1[G5743]   Drosophila melanogaster
FBal0282986 Not1[MI07631]   Drosophila melanogaster
FBal0245442 Not1[JF01135]   Drosophila melanogaster
FBal0257215 Not1[HMS00526]   Drosophila melanogaster
FBal0268931 Not1[dsRNA.Scer\UAS.WIZ]   Drosophila melanogaster
FBal0268932 Not1[Scer\UAS.T:Ivir\HA1]   Drosophila melanogaster
FBal0161968 Not1[dsRNA.cTa]   Drosophila melanogaster
FBal0287546 Not1[Scer\UAS.ORF.T:Ivir\HA1]   Drosophila melanogaster
FBal0239596 Not1[JF03096]   Drosophila melanogaster
FBal0207778 Not1[GD4070]   Drosophila melanogaster
FBal0207779 Not1[GD9640]   Drosophila melanogaster
FBal0230578 Not1[KK100090]   Drosophila melanogaster
FBal0221922 Not1[CB-0865-3]   Drosophila melanogaster
FBal0272958 Not1[NIG.1884R]   Drosophila melanogaster

101 Clones

Secondary Identifier DB identifier
FGH126B11 FBcl0388473
AI124264 FBcl0000761
AM02254 FBcl0000945
ESG0111c.B21.1_E09 FBcl0001104
UUGC0156 FBcl0001269
UUGC0853 FBcl0004751
ESG012c.E21_E10 FBcl0010717
AT01101 FBcl0039919
AT23282 FBcl0039931
EC32341 FBcl0071945
EP04060 FBcl0087819
EP18115 FBcl0087849
EP08821 FBcl0087875
EN06613 FBcl0100937
EN05513 FBcl0100951
GH26494 FBcl0129797
EK248763 FBcl0132034
EK177819 FBcl0132054
EK166062 FBcl0132060
EK253152 FBcl0132172
EK292851 FBcl0132178
EK067510 FBcl0132220
EK270011 FBcl0132244
EK109405 FBcl0132284
EK186062 FBcl0132290
EK146134 FBcl0132296
EK023240 FBcl0132302
EK163664 FBcl0132324
EK134006 FBcl0132420
EK219950 FBcl0132474

16 Exons

DB identifier Symbol
FBgn0085436:7 Not1:7
FBgn0085436:15 Not1:15
FBgn0085436:12 Not1:12
FBgn0085436:1 Not1:1
FBgn0085436:3 Not1:3
FBgn0085436:14 Not1:14
FBgn0085436:16 Not1:16
FBgn0085436:13 Not1:13
FBgn0085436:11 Not1:11
FBgn0085436:10 Not1:10
FBgn0085436:9 Not1:9
FBgn0085436:8 Not1:8
FBgn0085436:6 Not1:6
FBgn0085436:5 Not1:5
FBgn0085436:4 Not1:4
FBgn0085436:2 Not1:2

6 Transcripts

DB identifier Gene
FBtr0112673 Not1
FBtr0112674 Not1
FBtr0339394 Not1
FBtr0304957 Not1
FBtr0302122 Not1
FBtr0112672 Not1

12 UTRs

Class DB identifier
Organism . Name
FivePrimeUTR FBtr0112672-5-prime-utr Drosophila melanogaster
FivePrimeUTR FBtr0112673-5-prime-utr Drosophila melanogaster
FivePrimeUTR FBtr0112674-5-prime-utr Drosophila melanogaster
FivePrimeUTR FBtr0339394-5-prime-utr Drosophila melanogaster
FivePrimeUTR FBtr0304957-5-prime-utr Drosophila melanogaster
FivePrimeUTR FBtr0302122-5-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0112672-3-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0112673-3-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0112674-3-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0339394-3-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0304957-3-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0302122-3-prime-utr Drosophila melanogaster

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0 Pathways

2 Cross References

Identifier
Source . Name

Subject . Primary Identifier
5740252 NCBI Entrez Gene identifiers FBgn0085436
624883 BioGRID FBgn0085436

11 Data Sets

Name URL
FlyBase data set for Drosophila melanogaster  
TrEMBL data set http://www.ebi.ac.uk/trembl/
Drosophila 12 Genomes Consortium homology  
GenomeRNAi data set  
TreeFam data set  
Panther data set  
IntAct interactions data set  
BioGRID interaction data set http://www.thebiogrid.org/downloads.php
GO Annotation from FlyBase  
FlyBase fasta data set for Drosophila melanogaster  
Drosophila Cell Line and Developmental Stage Gene and Exon Scores  

55 Expression Scores


Gene . Primary Identifier

Submission . Title

Cell Line . Name

Developmental Stage . Name
Score
FBgn0085436 Drosophila Cell Line and Developmental Stage Gene and Exon Scores CME L1 2031.0
FBgn0085436 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Sg4 1966.0
FBgn0085436 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD11 2030.0
FBgn0085436 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD20-c2 1875.0
FBgn0085436 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD20-c5 2532.0
FBgn0085436 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Kc167 1388.0
FBgn0085436 Drosophila Cell Line and Developmental Stage Gene and Exon Scores GM2 3023.0
FBgn0085436 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S2-DRSC 2259.0
FBgn0085436 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S2R+ 1935.0
FBgn0085436 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S1 2494.0
FBgn0085436 Drosophila Cell Line and Developmental Stage Gene and Exon Scores 1182-4H 2850.0
FBgn0085436 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD16-c3 1882.0
FBgn0085436 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD32 1778.0
FBgn0085436 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD17-c3 2261.0
FBgn0085436 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD8 2827.0
FBgn0085436 Drosophila Cell Line and Developmental Stage Gene and Exon Scores CME W1 Cl.8+ 2037.0
FBgn0085436 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD9 2861.0
FBgn0085436 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmBG1-c1 2240.0
FBgn0085436 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD21 945.0
FBgn0085436 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD4-c1 1927.0
FBgn0085436 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmBG3-c2 1730.0
FBgn0085436 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S3 2869.0
FBgn0085436 Drosophila Cell Line and Developmental Stage Gene and Exon Scores CME W2 2360.0
FBgn0085436 Drosophila Cell Line and Developmental Stage Gene and Exon Scores mbn2 2652.0
FBgn0085436 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmBG2-c2 2802.0
FBgn0085436 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 0-2 h 3923.0
FBgn0085436 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 2-4 h 3716.0
FBgn0085436 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 4-6 h 2455.0
FBgn0085436 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 6-8 h 1987.0
FBgn0085436 Drosophila Cell Line and Developmental Stage Gene and Exon Scores emb 8-10h 1385.0

17 Introns

DB identifier
Organism . Name
intron_FBgn0085436:14_FBgn0085436:12 Drosophila melanogaster
intron_FBgn0085436:12_FBgn0085436:10 Drosophila melanogaster
intron_FBgn0085436:10_FBgn0085436:9 Drosophila melanogaster
intron_FBgn0085436:9_FBgn0085436:8 Drosophila melanogaster
intron_FBgn0085436:8_FBgn0085436:6 Drosophila melanogaster
intron_FBgn0085436:6_FBgn0085436:5 Drosophila melanogaster
intron_FBgn0085436:5_FBgn0085436:4 Drosophila melanogaster
intron_FBgn0085436:4_FBgn0085436:2 Drosophila melanogaster
intron_FBgn0085436:16_FBgn0085436:13 Drosophila melanogaster
intron_FBgn0085436:13_FBgn0085436:11 Drosophila melanogaster
intron_FBgn0085436:11_FBgn0085436:10 Drosophila melanogaster
intron_FBgn0085436:8_FBgn0085436:7 Drosophila melanogaster
intron_FBgn0085436:7_FBgn0085436:5 Drosophila melanogaster
intron_FBgn0085436:15_FBgn0085436:13 Drosophila melanogaster
intron_FBgn0085436:13_FBgn0085436:12 Drosophila melanogaster
intron_FBgn0085436:4_FBgn0085436:1 Drosophila melanogaster
intron_FBgn0085436:4_FBgn0085436:3 Drosophila melanogaster

62 RNAi Results

Screen Gene Phenotype Score Conditions PubMed ID
Lipid storage Not1 Increased lipid droplet area 7.144386683   19067489
Lipid storage Not1 Increased lipid droplet area 3.032983779   19067489
Lipid storage Not1 Increased lipid droplet area 2.855446768   19067489
Lipid storage Not1 Increased lipid droplet area 2.018026181   19067489
ERK signaling Not1 ERK activation reduced strong   17086199
ERK signaling Not1 ERK activation reduced weak   17086199
Hedgehog signaling Not1 Decreased Hedgehog reporter activity -2.3   16311596
Constitutive protein secretion and Golgi organization (1) Not1 Decreased horseradish peroxidase protein expression sp   16452979
Constitutive protein secretion and Golgi organization (1) Not1 Decreased horseradish peroxidase protein expression sp   16452979
Cell size and cell-cycle regulation (1) Not1 Increased G1 cell size sp   16496002
Cell size and cell-cycle regulation (1) Not1 none sp   16496002
Cell size and cell-cycle regulation (2) Not1 none 1.049   16496002
Cell size and cell-cycle regulation (3) Not1 none 461   16496002
Dendrite pattern formation Not1 Increased 1st branch extension, decreased lateral branching np   16547170
Microtubule assembly and organization Not1 none np   18463163
Muscle morphogenesis and function (1) Not1 Lethal np   20220848
Muscle morphogenesis and function (1) Not1 Lethal np   20220848
Muscle morphogenesis and function (1) Not1 Lethal np   20220848
Muscle morphogenesis and function (1) Not1 Lethal np   20220848
Muscle morphogenesis and function (1) Not1 Lethal np   20220848
Muscle morphogenesis and function (2) Not1 Wing posture / locomotion / ability to fly defect or lethal / semi-lethal np   20220848
Muscle morphogenesis and function (3) Not1 Split myofibril, fading Z-line np   20220848
Heat nociception (1) Not1 Developmentally lethal -1.17   21074052
Heat nociception (1) Not1 Lethal -1.17   21074052
Heat nociception (1) Not1 Developmentally lethal 0   21074052
Heart development and function (1) Not1 Adult lethal 0.42   20371351
Heart development and function (2) Not1 Decreased viability 3.37   20371351
Serratia marcescens infection (1) Not1 Decreased viability after Serratia marcescens infection -1.68181818181818   19520911
Serratia marcescens infection (1) Not1 none -0.852941176470588   19520911
Notch pathway regulation (4) Not1 Completely lethal (before pupal) sp   19363474

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