Genomics
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35 Alleles
176 Clones
10 Exons
| DB identifier | Symbol |
|---|---|
| FBgn0011274:8 | Dif:8 |
| FBgn0011274:7 | Dif:7 |
| FBgn0011274:6 | Dif:6 |
| FBgn0011274:5 | Dif:5 |
| FBgn0011274:4 | Dif:4 |
| FBgn0011274:3 | Dif:3 |
| FBgn0011274:1 | Dif:1 |
| FBgn0011274:9 | Dif:9 |
| FBgn0011274:2 | Dif:2 |
| FBgn0011274:10 | Dif:10 |
8 UTRs
| Class | DB identifier |
Organism . Name |
|---|---|---|
| FivePrimeUTR | FBtr0081008-5-prime-utr | Drosophila melanogaster |
| FivePrimeUTR | FBtr0081009-5-prime-utr | Drosophila melanogaster |
| FivePrimeUTR | FBtr0301577-5-prime-utr | Drosophila melanogaster |
| FivePrimeUTR | FBtr0301578-5-prime-utr | Drosophila melanogaster |
| ThreePrimeUTR | FBtr0081008-3-prime-utr | Drosophila melanogaster |
| ThreePrimeUTR | FBtr0081009-3-prime-utr | Drosophila melanogaster |
| ThreePrimeUTR | FBtr0301577-3-prime-utr | Drosophila melanogaster |
| ThreePrimeUTR | FBtr0301578-3-prime-utr | Drosophila melanogaster |
Other
46 Pathways
- MyD88 cascade initiated on plasma membrane,
- Toll Like Receptor 3 (TLR3) Cascade,
- Signaling by Interleukins,
- Innate Immune System,
- MyD88:Mal cascade initiated on plasma membrane,
- TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation,
- Interleukin-1 signaling,
- ZBP1(DAI) mediated induction of type I IFNs,
- Toll Like Receptor 2 (TLR2) Cascade,
- Toll Like Receptor 9 (TLR9) Cascade,
- TRAF6 Mediated Induction of proinflammatory cytokines,
- p75NTR signals via NF-kB,
- Fc epsilon receptor (FCERI) signaling,
- Toll Like Receptor 10 (TLR10) Cascade,
- Adaptive Immune System,
- Toll Like Receptor TLR6:TLR2 Cascade,
- Immune System,
- TCR signaling,
- IRAK2 mediated activation of TAK1 complex,
- Activated TLR4 signalling,
- p75 NTR receptor-mediated signalling,
- MyD88 dependent cascade initiated on endosome,
- NOD1/2 Signaling Pathway,
- Toll-Like Receptors Cascades,
- Toll Like Receptor 7/8 (TLR7/8) Cascade,
- Activation of NF-kappaB in B Cells,
- Signaling by NGF,
- RIG-I/MDA5 mediated induction of IFN-alpha/beta pathways,
- B Cell Activation,
- NF-kB is activated and signals survival,
- Cytosolic sensors of pathogen-associated DNA,
- Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways,
- DEx/H-box helicases activate type I IFN and inflammatory cytokines production,
- Signaling Pathways,
- Toll Like Receptor 4 (TLR4) Cascade,
- FCERI mediated NF-kB activation,
- Downstream Signaling Events Of B Cell Receptor (BCR),
- Toll Like Receptor TLR1:TLR2 Cascade,
- TAK1 activates NFkB by phosphorylation and activation of IKKs complex,
- MyD88-independent cascade,
- Downstream TCR signaling,
- Toll Like Receptor 5 (TLR5) Cascade,
- TRIF-mediated TLR3/TLR4 signaling,
- Cytokine Signaling in Immune system,
- RIP-mediated NFkB activation via ZBP1,
- TRAF6 mediated NF-kB activation
3 Cross References
| Identifier |
Source . Name |
Subject . Primary Identifier |
|---|---|---|
| 35045 | NCBI Entrez Gene identifiers | FBgn0011274 |
| 35044 | NCBI Entrez Gene identifiers | FBgn0011274 |
| 61041 | BioGRID | FBgn0011274 |
11 Data Sets
| Name | URL |
|---|---|
| FlyBase data set for Drosophila melanogaster | |
| Swiss-Prot data set | http://ca.expasy.org/sprot |
| Drosophila 12 Genomes Consortium homology | |
| GenomeRNAi data set | |
| TreeFam data set | |
| Panther data set | |
| IntAct interactions data set | |
| BioGRID interaction data set | http://www.thebiogrid.org/downloads.php |
| GO Annotation from FlyBase | |
| FlyBase fasta data set for Drosophila melanogaster | |
| Drosophila Cell Line and Developmental Stage Gene and Exon Scores |
55 Expression Scores
9 Introns
21 RNAi Results
| Screen | Gene | Phenotype | Score | Conditions | PubMed ID |
|---|---|---|---|---|---|
| Lipid storage | Dif | none | -0.780387626 | 19067489 | |
| Lipid storage | Dif | none | 0.605783442 | 19067489 | |
| Cell size and cell-cycle regulation (1) | Dif | none | sp | 16496002 | |
| Cell size and cell-cycle regulation (1) | Dif | none | sp | 16496002 | |
| Dendrite pattern formation | Dif | none | np | 16547170 | |
| Combinatorial effect with methyl methanesulphonate (1) | Dif | Synthetic lethal with methyl methanesulphonate | sp | 19543366 | |
| Muscle morphogenesis and function (1) | Dif | none | np | 20220848 | |
| Muscle morphogenesis and function (1) | Dif | none | np | 20220848 | |
| Heat nociception (1) | Dif | none | -1.17 | 21074052 | |
| Heat nociception (1) | Dif | none | -0.4 | 21074052 | |
| Serratia marcescens infection (1) | Dif | none | 0.494117647058823 | 19520911 | |
| Notch pathway regulation (4) | Dif | none | 0 | 19363474 | |
| Notch pathway regulation (4) | Dif | none | 0 | 19363474 | |
| Notch induced transcription | Dif | none | 0.6791 | without Notch stimulation | 20959007 |
| Notch induced transcription | Dif | Upregulation of Notch pathway after Notch stimulation | 2.0021 | N(delta)ecn Notch stimulation | 20959007 |
| Notch induced transcription | Dif | none | 0.737 | N(delta)ecn Notch stimulation | 20959007 |
| Adiposity regulation (1) | Dif | none | -0.724 | 20074523 | |
| Blood cell homeostasis regulation (1) | Dif | none | np | 20540764 | |
| Blood cell homeostasis regulation (2) | Dif | none | np | 20540764 | |
| Hippo pathway regulation | Dif | none | 0.11 | 23263283 | |
| Glycosylation regulation (1) | Dif | none | sp | 21203496 |
