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Gene : Hsc70Cb D. melanogaster

DB identifier  ? FBgn0026418 Secondary Identifier  ? CG6603
Name  ? Hsc70Cb Source  FlyBase
  • synonyms:
  • FBgn0028258,
  • HSC-70,
  • FBan0006603,
  • CG6603,
  • l(3)148513,
  • FBgn0027982,
  • l(3)00082,
  • l(3)S134802,
  • l(3)07621,
  • 0318/20,
  • FBgn0010924,
  • l(3)134217,
  • l(3)70Cb,
  • FBgn0026418,
  • hsc70Cb,
  • FBgn0026569,
  • 1342/17,
  • HSP110-1,
  • FBgn0010707,
  • l(3)S148513,
  • anon-WO0118547.302,
  • LD32772,
  • 1485/13,
  • 0041/12,
  • l(3)S134217,
  • FBgn0062110,
  • FBgn0028259,
  • dHsp110,
  • HSC70,
  • l(3)70Ca,
  • BEST:LD32772,
  • FBgn0013562,
  • 1348/02

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30 Alleles

DB identifier Symbol Allele Class Organism
FBal0212252 Hsc70Cb[YB0298]   Drosophila melanogaster
FBal0211695 Hsc70Cb[CB02656]   Drosophila melanogaster
FBal0183176 Hsc70Cb[d07917]   Drosophila melanogaster
FBal0183177 Hsc70Cb[d06126]   Drosophila melanogaster
FBal0183178 Hsc70Cb[d03562]   Drosophila melanogaster
FBal0183179 Hsc70Cb[c04771]   Drosophila melanogaster
FBal0009366 Hsc70Cb[00082]   Drosophila melanogaster
FBal0009602 Hsc70Cb[07621]   Drosophila melanogaster
FBal0043619 Hsc70Cb[06704]   Drosophila melanogaster
FBal0257744 Hsc70Cb[HMS01080]   Drosophila melanogaster
FBal0095842 Hsc70Cb[GS3087]   Drosophila melanogaster
FBal0099886 Hsc70Cb[S134802]   Drosophila melanogaster
FBal0100248 Hsc70Cb[S031820]   Drosophila melanogaster
FBal0100249 Hsc70Cb[S004112]   Drosophila melanogaster
FBal0095682 Hsc70Cb[S148513]   Drosophila melanogaster
FBal0095683 Hsc70Cb[S134217]   Drosophila melanogaster
FBal0118449 Hsc70Cb[S064906]   Drosophila melanogaster
FBal0156374 Hsc70Cb[KG03227a]   Drosophila melanogaster
FBal0261963 Hsc70Cb[CPTI002201]   Drosophila melanogaster
FBal0118448 Hsc70Cb[S132307a]   Drosophila melanogaster
FBal0031852 Hsc70Cb[1]   Drosophila melanogaster
FBal0261763 Hsc70Cb[CPTI002804]   Drosophila melanogaster
FBal0207335 Hsc70Cb[GD11973]   Drosophila melanogaster
FBal0227036 Hsc70Cb[UM-8096-3]   Drosophila melanogaster
FBal0227034 Hsc70Cb[EY00671]   Drosophila melanogaster
FBal0227035 Hsc70Cb[CB-5489-3]   Drosophila melanogaster
FBal0227037 Hsc70Cb[5-HA-2768]   Drosophila melanogaster
FBal0227038 Hsc70Cb[5-SZ-3315]   Drosophila melanogaster
FBal0227039 Hsc70Cb[5-SZ-3951]   Drosophila melanogaster
FBal0275205 Hsc70Cb[NIG.6603R]   Drosophila melanogaster

139 Clones

Secondary Identifier DB identifier
EK169946 FBcl0029656
UUGC0562 FBcl0004047
EK062201 FBcl0030048
EK256655 FBcl0030172
EK168853 FBcl0030244
EK071828 FBcl0030394
EK206937 FBcl0036542
EK249460 FBcl0034840
EK223110 FBcl0035574
AT16829 FBcl0018173
AT28763 FBcl0018219
AT04147 FBcl0018261
AT28924 FBcl0018263
AT27136 FBcl0018269
bs22e04 FBcl0050117
bs18c08 FBcl0050119
EP11249 FBcl0079125
EN15859 FBcl0094181
EN03350 FBcl0094191
GH24004 FBcl0134665
GH25571 FBcl0134671
GH26562 FBcl0134677
GH02128 FBcl0134681
GH08741 FBcl0134687
GH12450 FBcl0134715
GH02028 FBcl0134725
GH01807 FBcl0134727
GH11225 FBcl0134813
GH26584 FBcl0134819
GM05215 FBcl0140169

12 Exons

DB identifier Symbol
FBgn0026418:1 Hsc70Cb:1
FBgn0026418:4 Hsc70Cb:4
FBgn0026418:5 Hsc70Cb:5
FBgn0026418:7 Hsc70Cb:7
FBgn0026418:8 Hsc70Cb:8
FBgn0026418:10 Hsc70Cb:10
FBgn0026418:11 Hsc70Cb:11
FBgn0026418:2 Hsc70Cb:2
FBgn0026418:6 Hsc70Cb:6
FBgn0026418:9 Hsc70Cb:9
FBgn0026418:3 Hsc70Cb:3
FBgn0026418:12 Hsc70Cb:12

8 Transcripts

DB identifier Gene
FBtr0075773 Hsc70Cb
FBtr0075772 Hsc70Cb
FBtr0304035 Hsc70Cb
FBtr0304037 Hsc70Cb
FBtr0333051 Hsc70Cb
FBtr0075771 Hsc70Cb
FBtr0304036 Hsc70Cb
FBtr0304034 Hsc70Cb

16 UTRs

Class DB identifier
Organism . Name
FivePrimeUTR FBtr0075771-5-prime-utr Drosophila melanogaster
FivePrimeUTR FBtr0075772-5-prime-utr Drosophila melanogaster
FivePrimeUTR FBtr0075773-5-prime-utr Drosophila melanogaster
FivePrimeUTR FBtr0304034-5-prime-utr Drosophila melanogaster
FivePrimeUTR FBtr0304035-5-prime-utr Drosophila melanogaster
FivePrimeUTR FBtr0304036-5-prime-utr Drosophila melanogaster
FivePrimeUTR FBtr0304037-5-prime-utr Drosophila melanogaster
FivePrimeUTR FBtr0333051-5-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0075771-3-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0075772-3-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0075773-3-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0304034-3-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0304035-3-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0304036-3-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0304037-3-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0333051-3-prime-utr Drosophila melanogaster

Interactions

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Other

0 Pathways

2 Cross References

Identifier
Source . Name

Subject . Primary Identifier
39557 NCBI Entrez Gene identifiers FBgn0026418
64895 BioGRID FBgn0026418

10 Data Sets

Name URL
FlyBase data set for Drosophila melanogaster  
TrEMBL data set http://www.ebi.ac.uk/trembl/
Drosophila 12 Genomes Consortium homology  
GenomeRNAi data set  
TreeFam data set  
IntAct interactions data set  
BioGRID interaction data set http://www.thebiogrid.org/downloads.php
GO Annotation from FlyBase  
FlyBase fasta data set for Drosophila melanogaster  
Drosophila Cell Line and Developmental Stage Gene and Exon Scores  

55 Expression Scores


Gene . Primary Identifier

Submission . Title

Cell Line . Name

Developmental Stage . Name
Score
FBgn0026418 Drosophila Cell Line and Developmental Stage Gene and Exon Scores CME L1 3185.0
FBgn0026418 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Sg4 3694.0
FBgn0026418 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD11 2032.0
FBgn0026418 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD20-c2 4026.0
FBgn0026418 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD20-c5 3169.0
FBgn0026418 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Kc167 1731.0
FBgn0026418 Drosophila Cell Line and Developmental Stage Gene and Exon Scores GM2 2410.0
FBgn0026418 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S2-DRSC 3689.0
FBgn0026418 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S2R+ 1354.0
FBgn0026418 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S1 3669.0
FBgn0026418 Drosophila Cell Line and Developmental Stage Gene and Exon Scores 1182-4H 2538.0
FBgn0026418 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD16-c3 1801.0
FBgn0026418 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD32 1117.0
FBgn0026418 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD17-c3 3338.0
FBgn0026418 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD8 2168.0
FBgn0026418 Drosophila Cell Line and Developmental Stage Gene and Exon Scores CME W1 Cl.8+ 2964.0
FBgn0026418 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD9 2189.0
FBgn0026418 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmBG1-c1 2722.0
FBgn0026418 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD21 2089.0
FBgn0026418 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD4-c1 3475.0
FBgn0026418 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmBG3-c2 2394.0
FBgn0026418 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S3 4408.0
FBgn0026418 Drosophila Cell Line and Developmental Stage Gene and Exon Scores CME W2 2811.0
FBgn0026418 Drosophila Cell Line and Developmental Stage Gene and Exon Scores mbn2 2777.0
FBgn0026418 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmBG2-c2 2295.0
FBgn0026418 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 0-2 h 4028.0
FBgn0026418 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 2-4 h 998.0
FBgn0026418 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 4-6 h 1409.0
FBgn0026418 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 6-8 h 1554.0
FBgn0026418 Drosophila Cell Line and Developmental Stage Gene and Exon Scores emb 8-10h 1598.0

14 Introns

DB identifier
Organism . Name
intron_FBgn0026418:4_FBgn0026418:7 Drosophila melanogaster
intron_FBgn0026418:7_FBgn0026418:8 Drosophila melanogaster
intron_FBgn0026418:8_FBgn0026418:10 Drosophila melanogaster
intron_FBgn0026418:10_FBgn0026418:11 Drosophila melanogaster
intron_FBgn0026418:2_FBgn0026418:5 Drosophila melanogaster
intron_FBgn0026418:5_FBgn0026418:7 Drosophila melanogaster
intron_FBgn0026418:1_FBgn0026418:5 Drosophila melanogaster
intron_FBgn0026418:2_FBgn0026418:6 Drosophila melanogaster
intron_FBgn0026418:6_FBgn0026418:7 Drosophila melanogaster
intron_FBgn0026418:1_FBgn0026418:6 Drosophila melanogaster
intron_FBgn0026418:8_FBgn0026418:9 Drosophila melanogaster
intron_FBgn0026418:9_FBgn0026418:10 Drosophila melanogaster
intron_FBgn0026418:3_FBgn0026418:5 Drosophila melanogaster
intron_FBgn0026418:10_FBgn0026418:12 Drosophila melanogaster

28 RNAi Results

Screen Gene Phenotype Score Conditions PubMed ID
Lipid storage Hsc70Cb none 1.667628148   19067489
Lipid storage Hsc70Cb none -0.25487237   19067489
Lipid storage Hsc70Cb none 1.994676412   19067489
Cell size and cell-cycle regulation (1) Hsc70Cb none sp   16496002
Combinatorial effect with methyl methanesulphonate (1) Hsc70Cb none sp   19543366
Combinatorial effect with methyl methanesulphonate (2) Hsc70Cb Synthetic lethal with methyl methanesulphonate sp   19543366
Mutant human huntingtin aggregation Hsc70Cb Decreased mutant human huntingtin aggregation <= -2   19789644
Muscle morphogenesis and function (1) Hsc70Cb none np   20220848
Muscle morphogenesis and function (1) Hsc70Cb Flightless np   20220848
Heat nociception (1) Hsc70Cb none -0.62   21074052
Heart development and function (1) Hsc70Cb none 1   20371351
Heart development and function (1) Hsc70Cb none 1   20371351
Serratia marcescens infection (1) Hsc70Cb none -1.45588235294117   19520911
Notch pathway regulation (4) Hsc70Cb Loss of bristles, bristle morphology defects, notum malformation death sp   19363474
Notch pathway regulation (4) Hsc70Cb Loss of bristles 0.8   19363474
Adiposity regulation (1) Hsc70Cb Decreased triglyceride expression -0.593   20074523
Adiposity regulation (2) Hsc70Cb Decreased triglyceride expression -0.396   20074523
Adiposity regulation (3) Hsc70Cb none 0.104   20074523
Adiposity regulation (4) Hsc70Cb Lethal or developmental delay d/l   20074523
Adiposity regulation (5) Hsc70Cb none 0.087   20074523
S2 cell spreading Hsc70Cb none np   21041442
RTK-Ras-ERK pathway regulation (1) Hsc70Cb none -0.37 0 minutes EGF stimulation 22028469
RTK-Ras-ERK pathway regulation (1) Hsc70Cb none 0.31 10 minutes EGF stimulation 22028469
RTK-Ras-ERK pathway regulation (2) Hsc70Cb none 0.19 30 minutes sSpitz stimulation 22028469
RTK-Ras-ERK pathway regulation (2) Hsc70Cb Increased ERK phosphorylation after sSpitz and EGF stimulation 1.83 10 minutes sSpitz stimulation 22028469
Hippo pathway regulation Hsc70Cb none -2.3   23263283
Glycosylation regulation (1) Hsc70Cb none sp   21203496
Huntingtin (Htt) aggregates formation Hsc70Cb Increased formation of mutant Huntingtin (Httex1-Qn) protein aggregates np   20100940

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