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Gene : dco D. melanogaster

DB identifier  ? FBgn0002413 Secondary Identifier  ? CG2048
Name  ? discs overgrown Source  FlyBase
  • synonyms:
  • CK1epsilon,
  • Casein Kinase Iepsilon,
  • l(3)rK215,
  • DOUBLE-TIME,
  • ddbt,
  • CG2048,
  • Dco/CK1,
  • dCKIepsilon,
  • disc overgrown,
  • DBT,
  • DBT/CK1epsilon,
  • l(3)discs overgrown-1,
  • FBgn0011508,
  • FBgn0028129,
  • DCO,
  • dco-1,
  • CK1delta/epsilon,
  • 0915/10,
  • l(3)dco,
  • Discs overgrown,
  • FBgn0002413,
  • CKIepsilon,
  • DCO/CKIe,
  • l(3)S053813,
  • 1447/01,
  • DOUBLETIME,
  • FBan0002048,
  • l(3)dco-1,
  • FBgn0024895,
  • Double time,
  • Casein Kinase I epsilon,
  • FBgn0027967,
  • 0538/13,
  • 1460/09,
  • l(3)discs overgrown,
  • l(3)S144701,
  • l(3)j3B9,
  • 1396/02,
  • FBgn0011349

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106 Alleles

DB identifier Symbol Allele Class Organism
FBal0197555 dco[KD.Scer\UAS]   Drosophila melanogaster
FBal0155408 dco[dsRNA.481-1232]   Drosophila melanogaster
FBal0218903 dco[DG20105]   Drosophila melanogaster
FBal0282778 dco[Scer\UAS.cUa]   Drosophila melanogaster
FBal0180237 dco[d00711]   Drosophila melanogaster
FBal0245372 dco[HM04075]   Drosophila melanogaster
FBal0180236 dco[d06510]   Drosophila melanogaster
FBal0180234 dco[f04615]   Drosophila melanogaster
FBal0180235 dco[e03697]   Drosophila melanogaster
FBal0261059 dco[3.Scer\UAS.T:SV5\V5,T:Zzzz\His6]   Drosophila melanogaster
FBal0180238 dco[c00630]   Drosophila melanogaster
FBal0180239 dco[c00028]   Drosophila melanogaster
FBal0159333 dco[EY02910]   Drosophila melanogaster
FBal0010937 dco[j3B9] loss of function allele Drosophila melanogaster
FBal0011112 dco[rK215]   Drosophila melanogaster
FBal0130430 dco[EP3280]   Drosophila melanogaster
FBal0260858 dco[t.L39Q]   Drosophila melanogaster
FBal0260859 dco[t.S101R]   Drosophila melanogaster
FBal0264169 dco[kinase.Scer\UAS]   Drosophila melanogaster
FBal0099868 dco[S144701] hypomorphic allele - genetic evidence Drosophila melanogaster
FBal0100077 dco[S139602] hypomorphic allele - genetic evidence Drosophila melanogaster
FBal0100078 dco[S091510] hypomorphic allele - genetic evidence Drosophila melanogaster
FBal0100079 dco[S053813] loss of function allele Drosophila melanogaster
FBal0102767 dco[P103] hypomorphic allele - genetic evidence Drosophila melanogaster
FBal0264170 dco[hs.PS]   Drosophila melanogaster
FBal0248558 dco[s139602-REV]   Drosophila melanogaster
FBal0285928 dco[Tau.Scer\UAS.T:Hsap\MYC]   Drosophila melanogaster
FBal0285852 dco[S.Scer\UAS.T:Hsap\MYC]   Drosophila melanogaster
FBal0285853 dco[L.Scer\UAS.T:Hsap\MYC]   Drosophila melanogaster
FBal0285854 dco[K38R.Scer\UAS.T:Hsap\MYC]   Drosophila melanogaster

59 Clones

Secondary Identifier DB identifier
AT02885 FBcl0038683
AT10612 FBcl0038695
CK00445 FBcl0060385
EP16839 FBcl0087367
EN10617 FBcl0100591
EN03728 FBcl0100623
EK173535 FBcl0138724
EK211555 FBcl0138788
EK107508 FBcl0138796
EK042554 FBcl0138800
EK163111 FBcl0138816
EK205362 FBcl0138854
EK085902 FBcl0138882
EK189653 FBcl0139052
EK190506 FBcl0139472
EK113957 FBcl0140796
GM32617 FBcl0147864
HL01564 FBcl0148998
LD04938 FBcl0152773
LD05767 FBcl0152775
LD07908 FBcl0152777
LD01207 FBcl0152793
LD20845 FBcl0152797
LD11131 FBcl0152799
LD06839 FBcl0152800
LD16647 FBcl0152801
LD10150 FBcl0152803
LD02617 FBcl0152805
LD19404 FBcl0152811
LD27173 FBcl0165457

8 Exons

DB identifier Symbol
FBgn0002413:3 dco:3
FBgn0002413:8 dco:8
FBgn0002413:4 dco:4
FBgn0002413:2 dco:2
FBgn0002413:7 dco:7
FBgn0002413:5 dco:5
FBgn0002413:6 dco:6
FBgn0002413:1 dco:1

4 Transcripts

DB identifier Gene
FBtr0085743 dco
FBtr0334548 dco
FBtr0085744 dco
FBtr0085742 dco

8 UTRs

Class DB identifier
Organism . Name
FivePrimeUTR FBtr0085742-5-prime-utr Drosophila melanogaster
FivePrimeUTR FBtr0085743-5-prime-utr Drosophila melanogaster
FivePrimeUTR FBtr0085744-5-prime-utr Drosophila melanogaster
FivePrimeUTR FBtr0334548-5-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0085742-3-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0085743-3-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0085744-3-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0334548-3-prime-utr Drosophila melanogaster

Interactions

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Other

0 Pathways

2 Cross References

Identifier
Source . Name

Subject . Primary Identifier
43673 NCBI Entrez Gene identifiers FBgn0002413
68523 BioGRID FBgn0002413

11 Data Sets

Name URL
FlyBase data set for Drosophila melanogaster  
Swiss-Prot data set http://ca.expasy.org/sprot
Drosophila 12 Genomes Consortium homology  
GenomeRNAi data set  
TreeFam data set  
Panther data set  
IntAct interactions data set  
BioGRID interaction data set http://www.thebiogrid.org/downloads.php
GO Annotation from FlyBase  
FlyBase fasta data set for Drosophila melanogaster  
Drosophila Cell Line and Developmental Stage Gene and Exon Scores  

55 Expression Scores


Gene . Primary Identifier

Submission . Title

Cell Line . Name

Developmental Stage . Name
Score
FBgn0002413 Drosophila Cell Line and Developmental Stage Gene and Exon Scores CME L1 1486.0
FBgn0002413 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Sg4 1571.0
FBgn0002413 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD11 1121.0
FBgn0002413 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD20-c2 1611.0
FBgn0002413 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD20-c5 1474.0
FBgn0002413 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Kc167 2265.0
FBgn0002413 Drosophila Cell Line and Developmental Stage Gene and Exon Scores GM2 1600.0
FBgn0002413 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S2-DRSC 2851.0
FBgn0002413 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S2R+ 1896.0
FBgn0002413 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S1 2760.0
FBgn0002413 Drosophila Cell Line and Developmental Stage Gene and Exon Scores 1182-4H 2590.0
FBgn0002413 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD16-c3 1439.0
FBgn0002413 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD32 1988.0
FBgn0002413 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD17-c3 1688.0
FBgn0002413 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD8 3047.0
FBgn0002413 Drosophila Cell Line and Developmental Stage Gene and Exon Scores CME W1 Cl.8+ 1980.0
FBgn0002413 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD9 2950.0
FBgn0002413 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmBG1-c1 1715.0
FBgn0002413 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD21 2402.0
FBgn0002413 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD4-c1 2152.0
FBgn0002413 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmBG3-c2 2794.0
FBgn0002413 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S3 2618.0
FBgn0002413 Drosophila Cell Line and Developmental Stage Gene and Exon Scores CME W2 1293.0
FBgn0002413 Drosophila Cell Line and Developmental Stage Gene and Exon Scores mbn2 2240.0
FBgn0002413 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmBG2-c2 1441.0
FBgn0002413 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 0-2 h 10636.0
FBgn0002413 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 2-4 h 5950.0
FBgn0002413 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 4-6 h 3528.0
FBgn0002413 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 6-8 h 3248.0
FBgn0002413 Drosophila Cell Line and Developmental Stage Gene and Exon Scores emb 8-10h 4343.0

8 Introns

DB identifier
Organism . Name
intron_FBgn0002413:7_FBgn0002413:5 Drosophila melanogaster
intron_FBgn0002413:5_FBgn0002413:3 Drosophila melanogaster
intron_FBgn0002413:3_FBgn0002413:2 Drosophila melanogaster
intron_FBgn0002413:8_FBgn0002413:4 Drosophila melanogaster
intron_FBgn0002413:4_FBgn0002413:2 Drosophila melanogaster
intron_FBgn0002413:6_FBgn0002413:3 Drosophila melanogaster
intron_FBgn0002413:8_FBgn0002413:5 Drosophila melanogaster
intron_FBgn0002413:3_FBgn0002413:1 Drosophila melanogaster

45 RNAi Results

Screen Gene Phenotype Score Conditions PubMed ID
Lipid storage dco none 1.045432191   19067489
Lipid storage dco none 0   19067489
ERK signaling dco ERK activation increased strong   17086199
Cell morphology dco Morphology np   14527345
Cell cycle regulation (1) dco none np   15616552
Cell cycle regulation (2) dco none np   15616552
L. monocytogenes infection dco Escape pff LLO- strain *   16157870
Cell size and cell-cycle regulation (1) dco none sp   16496002
Cell size and cell-cycle regulation (1) dco none sp   16496002
Cell size and cell-cycle regulation (1) dco none sp   16496002
Cell size and cell-cycle regulation (1) dco none sp   16496002
Cell size and cell-cycle regulation (1) dco none sp   16496002
Dendrite pattern formation dco none np   16547170
C. trachomatis infection dco C. trachomatis infection down np   18369471
Microtubule assembly and organization dco none np   18463163
Combinatorial effect with methyl methanesulphonate (2) dco none sp   19543366
Muscle morphogenesis and function (1) dco none np   20220848
Heat nociception (1) dco none 0.46   21074052
Heart development and function (1) dco none 1   20371351
Serratia marcescens infection (1) dco none 0.838235294117647   19520911
Notch pathway regulation (4) dco Bristle morphology defects, notum malformation death sp   19363474
PGN-induced dJNK phosphorylation dco Increased P-JNK protein expression with PGN 2.27 60 min PGN induction 19893628
Adiposity regulation (1) dco none -0.356   20074523
Blood cell homeostasis regulation (1) dco Increased melanotic mass formation np   20540764
Blood cell homeostasis regulation (2) dco none np   20540764
Blood cell homeostasis regulation (3) dco Increased melanotic mass formation 8.9   20540764
Blood cell homeostasis regulation (4) dco none 0   20540764
Blood cell homeostasis regulation (5) dco Increased melanotic mass formation 51.4   20540764
Blood cell homeostasis regulation (6) dco none 0   20540764
Blood cell homeostasis regulation (7) dco none 0   20540764

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