Genomics
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140 Alleles
80 Clones
4 UTRs
| Class | DB identifier |
Organism . Name |
|---|---|---|
| FivePrimeUTR | FBtr0085397-5-prime-utr | Drosophila melanogaster |
| FivePrimeUTR | FBtr0334867-5-prime-utr | Drosophila melanogaster |
| ThreePrimeUTR | FBtr0085397-3-prime-utr | Drosophila melanogaster |
| ThreePrimeUTR | FBtr0334867-3-prime-utr | Drosophila melanogaster |
Other
78 Pathways
- Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase,
- DNA Replication Pre-Initiation,
- p53-Independent DNA Damage Response,
- APC/C:Cdc20 mediated degradation of Cyclin B,
- Homologous recombination repair of replication-independent double-strand breaks,
- Homologous Recombination Repair,
- Cyclin A:Cdk2-associated events at S phase entry,
- G1/S Transition,
- Synthesis of DNA,
- Polo-like kinase mediated events,
- B Cell Activation,
- Mitotic M-M/G1 phases,
- G2/M Checkpoints,
- Mitotic Anaphase,
- Degradation of beta-catenin by the destruction complex,
- p53-Independent G1/S DNA damage checkpoint,
- Beta-catenin phosphorylation cascade,
- Regulation of activated PAK-2p34 by proteasome mediated degradation,
- Cyclin B2 mediated events,
- Adaptive Immune System,
- Orc1 removal from chromatin,
- G0 and Early G1,
- Removal of licensing factors from origins,
- E2F-enabled inhibition of pre-replication complex formation,
- G2/M DNA damage checkpoint,
- Regulation of Apoptosis,
- Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins,
- APC/C-mediated degradation of cell cycle proteins,
- M Phase,
- Regulation of mitotic cell cycle,
- APC/C:Cdc20 mediated degradation of mitotic proteins,
- Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex,
- Activation of ATR in response to replication stress,
- ATM mediated response to DNA double-strand break,
- CDK-mediated phosphorylation and removal of Cdc6,
- Separation of Sister Chromatids,
- DNA Repair,
- Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal,
- Cdc20:Phospho-APC/C mediated degradation of Cyclin A,
- Amplification of signal from the kinetochores,
- Apoptosis,
- Immune System,
- SCF-beta-TrCP mediated degradation of Emi1,
- Ubiquitin Mediated Degradation of Phosphorylated Cdc25A,
- G1/S DNA Damage Checkpoints,
- Mitotic Metaphase and Anaphase,
- Cyclin E associated events during G1/S transition,
- Inactivation of APC/C via direct inhibition of the APC/C complex,
- APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1,
- Cyclin A/B1 associated events during G2/M transition,
- DNA Replication,
- Mitotic G1-G1/S phases,
- Antigen processing: Ubiquitination & Proteasome degradation,
- S Phase,
- Mitotic Spindle Checkpoint,
- G2/M DNA replication checkpoint,
- Cell Cycle Checkpoints,
- G1/S-Specific Transcription,
- Activation of NF-kappaB in B Cells,
- Double-Strand Break Repair,
- Cell Cycle,
- Class I MHC mediated antigen processing & presentation,
- Downstream Signaling Events Of B Cell Receptor (BCR),
- M/G1 Transition,
- Signaling Pathways,
- G2/M Transition,
- Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components,
- ER-Phagosome pathway,
- Antigen processing-Cross presentation,
- Regulation of DNA replication,
- Cross-presentation of soluble exogenous antigens (endosomes),
- APC/C:Cdc20 mediated degradation of Securin,
- E2F mediated regulation of DNA replication,
- Switching of origins to a post-replicative state,
- Cell Cycle, Mitotic,
- Regulation of APC/C activators between G1/S and early anaphase,
- Mitotic G2-G2/M phases,
- Signaling by Wnt
2 Cross References
| Identifier |
Source . Name |
Subject . Primary Identifier |
|---|---|---|
| 43466 | NCBI Entrez Gene identifiers | FBgn0003525 |
| 68333 | BioGRID | FBgn0003525 |
11 Data Sets
| Name | URL |
|---|---|
| FlyBase data set for Drosophila melanogaster | |
| Swiss-Prot data set | http://ca.expasy.org/sprot |
| Drosophila 12 Genomes Consortium homology | |
| GenomeRNAi data set | |
| TreeFam data set | |
| Panther data set | |
| IntAct interactions data set | |
| BioGRID interaction data set | http://www.thebiogrid.org/downloads.php |
| GO Annotation from FlyBase | |
| FlyBase fasta data set for Drosophila melanogaster | |
| Drosophila Cell Line and Developmental Stage Gene and Exon Scores |
55 Expression Scores
2 Introns
| DB identifier |
Organism . Name |
|---|---|
| intron_FBgn0003525:3_FBgn0003525:1 | Drosophila melanogaster |
| intron_FBgn0003525:3_FBgn0003525:2 | Drosophila melanogaster |
28 RNAi Results
| Screen | Gene | Phenotype | Score | Conditions | PubMed ID |
|---|---|---|---|---|---|
| Lipid storage | stg | none | 2.351984079 | 19067489 | |
| Lipid storage | stg | none | 0.674490759 | 19067489 | |
| Cell morphology | stg | Morphology | np | 14527345 | |
| Cytokinesis regulation | stg | Binucleate cells | weak | 15547975 | |
| L. monocytogenes infection | stg | More bacteria per cell | *** | 16157870 | |
| Wnt signaling | stg | Decreased Wnt reporter activity | -0.68 | 15817814 | |
| Cell size and cell-cycle regulation (1) | stg | none | sp | 16496002 | |
| Cell size and cell-cycle regulation (1) | stg | Decreased G1 DNA content | sp | 16496002 | |
| Cell size and cell-cycle regulation (2) | stg | none | 1.156 | 16496002 | |
| Cell size and cell-cycle regulation (3) | stg | none | 457 | 16496002 | |
| Cell size and cell-cycle regulation (4) | stg | none | below threshold | 16496002 | |
| Heart development and function | stg | Heart patterning defects | np | 14684833 | |
| Lipid storage | stg | Fewer lipid droplets | strong | 18408709 | |
| Combinatorial effect with methyl methanesulphonate (2) | stg | none | sp | 19543366 | |
| Muscle morphogenesis and function (1) | stg | none | np | 20220848 | |
| Heart development and function (1) | stg | none | 1 | 20371351 | |
| Serratia marcescens infection (1) | stg | none | 0.878378378378378 | 19520911 | |
| Notch pathway regulation (4) | stg | Loss of bristles, bristle morphology defects, lateral inhibition | sp | 19363474 | |
| Adiposity regulation (1) | stg | none | -0.344 | 20074523 | |
| Blood cell homeostasis regulation (1) | stg | none | np | 20540764 | |
| Blood cell homeostasis regulation (2) | stg | none | np | 20540764 | |
| Vaccinia virus infection | stg | none | sp | 20585561 | |
| RTK-Ras-ERK pathway regulation (1) | stg | Decreased ERK phosphorylation after EGF stimulation | -3.72 | 10 minutes EGF stimulation | 22028469 |
| RTK-Ras-ERK pathway regulation (1) | stg | none | -0.84 | 0 minutes EGF stimulation | 22028469 |
| RTK-Ras-ERK pathway regulation (2) | stg | Increased ERK phosphorylation after sSpitz and EGF stimulation | 8.76 | 10 minutes sSpitz stimulation | 22028469 |
| RTK-Ras-ERK pathway regulation (2) | stg | Increased ERK phosphorylation after sSpitz and EGF stimulation | 12.05 | 30 minutes sSpitz stimulation | 22028469 |
| Hippo pathway regulation | stg | none | -2.15 | 23263283 | |
| Glycosylation regulation (1) | stg | none | sp | 21203496 |
