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Gene : brm D. melanogaster

DB identifier  ? FBgn0000212 Secondary Identifier  ? CG5942
Name  ? brahma Source  FlyBase
  • synonyms:
  • CG18438,
  • Complementation group 3.5,
  • CG5942,
  • l(3)72Aa,
  • Brahma,
  • FBgn0036554,
  • FBgn0000212,
  • BRM,
  • FBan0005942,
  • E(E2F)3A,
  • dSNF2,
  • dBRM

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58 Alleles

DB identifier Symbol Allele Class Organism
FBal0218960 brm[9573]   Drosophila melanogaster
FBal0246317 brm[Scer\UAS.cHa]   Drosophila melanogaster
FBal0280246 brm[Scer\UAS.cBa]   Drosophila melanogaster
FBal0239118 brm[f04692]   Drosophila melanogaster
FBal0245321 brm[HM04019]   Drosophila melanogaster
FBal0180664 brm[e00449]   Drosophila melanogaster
FBal0159441 brm[d00415]   Drosophila melanogaster
FBal0030646 brm[10]   Drosophila melanogaster
FBal0030647 brm[8]   Drosophila melanogaster
FBal0030648 brm[9]   Drosophila melanogaster
FBal0249254 brm[MI01941]   Drosophila melanogaster
FBal0001296 brm[2] amorphic allele - genetic evidence Drosophila melanogaster
FBal0001295 brm[1] hypomorphic allele - genetic evidence Drosophila melanogaster
FBal0039171 brm[12]   Drosophila melanogaster
FBal0039181 brm[R10.8]   Drosophila melanogaster
FBal0039170 brm[+t14.4]   Drosophila melanogaster
FBal0086708 brm[Delta1446-1517]   Drosophila melanogaster
FBal0049360 brm[unspecified]   Drosophila melanogaster
FBal0001300 brm[6]   Drosophila melanogaster
FBal0120537 brm[T362]   Drosophila melanogaster
FBal0191770 brm[3244]   Drosophila melanogaster
FBal0101489 brm[pjc-2]   Drosophila melanogaster
FBal0120536 brm[T808]   Drosophila melanogaster
FBal0189680 brm[3369]   Drosophila melanogaster
FBal0039172 brm[13]   Drosophila melanogaster
FBal0039175 brm[16]   Drosophila melanogaster
FBal0039173 brm[14]   Drosophila melanogaster
FBal0155546 brm[T485]   Drosophila melanogaster
FBal0190073 brm[1630]   Drosophila melanogaster
FBal0147253 brm[25S14]   Drosophila melanogaster

60 Clones

Secondary Identifier DB identifier
EK170527 FBcl0051672
EK178913 FBcl0051764
EK229951 FBcl0051838
EK069741 FBcl0052140
EK009517 FBcl0052180
EK295532 FBcl0052194
EK197027 FBcl0052200
EK166242 FBcl0052204
EK021355 FBcl0052210
EK230933 FBcl0052228
EN12124 FBcl0093203
GH25336 FBcl0106431
GH23970 FBcl0106435
GH23737 FBcl0106529
GM04283 FBcl0139423
LD18622 FBcl0152244
LD15103 FBcl0152245
LD15643 FBcl0152261
LD08257 FBcl0152290
LD31222 FBcl0164806
LD36356 FBcl0164808
LD36901 FBcl0164812
LD25352 FBcl0164825
RE41074 FBcl0197016
RE39907 FBcl0197017
RE35419 FBcl0197020
RE61274 FBcl0197061
RE54055 FBcl0197064
RE73909 FBcl0197067
RE26666 FBcl0197070

10 Exons

DB identifier Symbol
FBgn0000212:10 brm:10
FBgn0000212:8 brm:8
FBgn0000212:6 brm:6
FBgn0000212:3 brm:3
FBgn0000212:2 brm:2
FBgn0000212:1 brm:1
FBgn0000212:5 brm:5
FBgn0000212:7 brm:7
FBgn0000212:9 brm:9
FBgn0000212:4 brm:4

6 Transcripts

DB identifier Gene
FBtr0075526 brm
FBtr0075523 brm
FBtr0075525 brm
FBtr0330160 brm
FBtr0333580 brm
FBtr0075524 brm

12 UTRs

Class DB identifier
Organism . Name
FivePrimeUTR FBtr0075523-5-prime-utr Drosophila melanogaster
FivePrimeUTR FBtr0075524-5-prime-utr Drosophila melanogaster
FivePrimeUTR FBtr0075525-5-prime-utr Drosophila melanogaster
FivePrimeUTR FBtr0075526-5-prime-utr Drosophila melanogaster
FivePrimeUTR FBtr0330160-5-prime-utr Drosophila melanogaster
FivePrimeUTR FBtr0333580-5-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0075523-3-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0075524-3-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0075525-3-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0075526-3-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0330160-3-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0333580-3-prime-utr Drosophila melanogaster

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Other

0 Pathways

2 Cross References

Identifier
Source . Name

Subject . Primary Identifier
39744 NCBI Entrez Gene identifiers FBgn0000212
65055 BioGRID FBgn0000212

12 Data Sets

Name URL
FlyBase data set for Drosophila melanogaster  
Swiss-Prot data set http://ca.expasy.org/sprot
Drosophila 12 Genomes Consortium homology  
GenomeRNAi data set  
TreeFam data set  
Panther data set  
IntAct interactions data set  
BioGRID interaction data set http://www.thebiogrid.org/downloads.php
GO Annotation from FlyBase  
FlyBase fasta data set for Drosophila melanogaster  
Drosophila Cell Line and Developmental Stage Gene and Exon Scores  
Fly Transcription Factor/microRNA Regulatory Network  

55 Expression Scores


Gene . Primary Identifier

Submission . Title

Cell Line . Name

Developmental Stage . Name
Score
FBgn0000212 Drosophila Cell Line and Developmental Stage Gene and Exon Scores CME L1 2007.0
FBgn0000212 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Sg4 1399.0
FBgn0000212 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD11 1210.0
FBgn0000212 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD20-c2 1063.0
FBgn0000212 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD20-c5 1045.0
FBgn0000212 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Kc167 1364.0
FBgn0000212 Drosophila Cell Line and Developmental Stage Gene and Exon Scores GM2 1238.0
FBgn0000212 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S2-DRSC 1730.0
FBgn0000212 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S2R+ 1115.0
FBgn0000212 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S1 1365.0
FBgn0000212 Drosophila Cell Line and Developmental Stage Gene and Exon Scores 1182-4H 1029.0
FBgn0000212 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD16-c3 1088.0
FBgn0000212 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD32 944.0
FBgn0000212 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD17-c3 2019.0
FBgn0000212 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD8 1475.0
FBgn0000212 Drosophila Cell Line and Developmental Stage Gene and Exon Scores CME W1 Cl.8+ 1189.0
FBgn0000212 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD9 1589.0
FBgn0000212 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmBG1-c1 1333.0
FBgn0000212 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD21 1028.0
FBgn0000212 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD4-c1 968.0
FBgn0000212 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmBG3-c2 1249.0
FBgn0000212 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S3 1345.0
FBgn0000212 Drosophila Cell Line and Developmental Stage Gene and Exon Scores CME W2 1166.0
FBgn0000212 Drosophila Cell Line and Developmental Stage Gene and Exon Scores mbn2 1200.0
FBgn0000212 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmBG2-c2 1080.0
FBgn0000212 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 0-2 h 2632.0
FBgn0000212 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 2-4 h 2695.0
FBgn0000212 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 4-6 h 2517.0
FBgn0000212 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 6-8 h 2340.0
FBgn0000212 Drosophila Cell Line and Developmental Stage Gene and Exon Scores emb 8-10h 2182.0

12 Introns

DB identifier
Organism . Name
intron_FBgn0000212:9_FBgn0000212:6 Drosophila melanogaster
intron_FBgn0000212:6_FBgn0000212:3 Drosophila melanogaster
intron_FBgn0000212:3_FBgn0000212:2 Drosophila melanogaster
intron_FBgn0000212:2_FBgn0000212:1 Drosophila melanogaster
intron_FBgn0000212:10_FBgn0000212:8 Drosophila melanogaster
intron_FBgn0000212:8_FBgn0000212:5 Drosophila melanogaster
intron_FBgn0000212:5_FBgn0000212:3 Drosophila melanogaster
intron_FBgn0000212:8_FBgn0000212:6 Drosophila melanogaster
intron_FBgn0000212:5_FBgn0000212:4 Drosophila melanogaster
intron_FBgn0000212:4_FBgn0000212:3 Drosophila melanogaster
intron_FBgn0000212:10_FBgn0000212:7 Drosophila melanogaster
intron_FBgn0000212:7_FBgn0000212:5 Drosophila melanogaster

33 RNAi Results

Screen Gene Phenotype Score Conditions PubMed ID
Lipid storage brm Increased lipid droplet area 6.853479214   19067489
Lipid storage brm Increased lipid droplet area 8.695161858   19067489
Insect dengue virus infection brm Inhibition of dengue virus propagation 3 (0.0027)   19396146
ERK signaling brm ERK activation reduced strong   17086199
Cell size and cell-cycle regulation (1) brm none sp   16496002
Cell size and cell-cycle regulation (1) brm none sp   16496002
Candida albicans phagocytosis (1) brm Decreased Candida albicans phagocytosis np   16336044
Candida albicans phagocytosis (2) brm Decreased Escherichia coli phagocytosis 42   16336044
Candida albicans phagocytosis (3) brm Decreased latex beads phagocytosis 33   16336044
Ca2+ channel regulation brm Decreased Ca2+ influx 4   16645049
Dendrite pattern formation brm Misrouting np   16547170
Mitochondrial biogenesis and function brm Decreased mitochondrial citrate synthase activity 0.638   18042644
Mutant human huntingtin aggregation brm Increased mutant human huntingtin aggregation >= 2   19789644
Muscle morphogenesis and function (1) brm none np   20220848
Muscle morphogenesis and function (1) brm none np   20220848
Heat nociception (1) brm none -1.17   21074052
Heat nociception (1) brm Developmentally lethal 0.02   21074052
Heart development and function (1) brm none 1   20371351
Serratia marcescens infection (1) brm none 0.723076923076923   19520911
Notch pathway regulation (4) brm Completely lethal (pupal) sp   19363474
Notch pathway regulation (4) brm Completely lethal (pupal) sp   19363474
Toll-dependent innate immune pathway regulation brm Upregulation of Toll pathway after hEGF stimulation 4.87   20375635
Self-renewal and differentiation in neural stem cells brm Neuroblast more large cells, ganglion mother cell shorter lineages, neuroblast overproliferation, neuroblast underproliferation, lethal sp   21549331
Self-renewal and differentiation in neural stem cells brm GFP aggregates size, neuroblast more large cells, ganglion mother cell shorter lineages, neuroblast overproliferation, neuroblast underproliferation, lethal sp   21549331
Pol II elongation brm none 91 20 min heat shock 19279664
Adiposity regulation (1) brm none -0.022   20074523
RTK-Ras-ERK pathway regulation (1) brm Decreased ERK phosphorylation after EGF stimulation -2.09 0 minutes EGF stimulation 22028469
RTK-Ras-ERK pathway regulation (1) brm none 0.36 10 minutes EGF stimulation 22028469
RTK-Ras-ERK pathway regulation (2) brm none 0.61 10 minutes sSpitz stimulation 22028469
RTK-Ras-ERK pathway regulation (2) brm Increased ERK phosphorylation after sSpitz and EGF stimulation 2.42 30 minutes sSpitz stimulation 22028469

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