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Gene : DNApol-alpha50 D. melanogaster

DB identifier  ? FBgn0011762 Secondary Identifier  ? CG7108
Name  ? DNA polymerase alpha 50kD Source  FlyBase
  • synonyms:
  • dnapol alpha 50,
  • FBan0007108,
  • DNApolalpha,
  • DNA polymerase alpha 50 kda primase subunit,
  • DNA polalpha,
  • DNA polymerase alpha 46,000 gamma subunit,
  • Polalpha,
  • anon-WO0140519.257,
  • DNA-polymerase alpha,
  • CG7108,
  • Pol,
  • FBgn0044611,
  • Dpri50,
  • p50 subunit of DNA polymerase alpha,
  • FBgn0011762,
  • Polalpha 50kDa,
  • DNApol-alpha,
  • polalpha50,
  • DNA polymerase 50K,
  • POLA,
  • Dmpol alpha,
  • DNApol-alpha50,
  • PRI1,
  • DNApolalpha50,
  • pol alpha,
  • DNA polymerase alpha,
  • DNA polymerase alpha 50,000 gamma subunit

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8 Alleles

DB identifier Symbol Allele Class Organism
FBal0220908 DNApol-alpha50[G6398]   Drosophila melanogaster
FBal0220851 DNApol-alpha50[G3879]   Drosophila melanogaster
FBal0184213 DNApol-alpha50[f07480]   Drosophila melanogaster
FBal0160641 DNApol-alpha50[f02992]   Drosophila melanogaster
FBal0206808 DNApol-alpha50[GD4566]   Drosophila melanogaster
FBal0268532 DNApol-alpha50[NIG.cUa]   Drosophila melanogaster
FBal0275433 DNApol-alpha50[NIG.7108-1R]   Drosophila melanogaster
FBal0275434 DNApol-alpha50[NIG.7108-2R]   Drosophila melanogaster

82 Clones

Secondary Identifier DB identifier
ESG011b.E21_F02 FBcl0011425
EP09644 FBcl0085051
EK199829 FBcl0103760
EK159830 FBcl0103792
EK182303 FBcl0103808
EK104502 FBcl0105232
GH27162 FBcl0120689
GM05107 FBcl0142430
LD46032 FBcl0164465
RE33137 FBcl0224396
RE72527 FBcl0226357
RE26079 FBcl0226396
RE64823 FBcl0226431
RE69920 FBcl0226439
RE33219 FBcl0226444
Dmel_neb_009574_0564_2701 FBcl0381284
FGH119G07 FBcl0388013
RP003242553 FBcl0655593
RP003189633 FBcl0655594
RP003484556 FBcl0655595
RP003582514 FBcl0655596
RP003528898 FBcl0655597
RP003333976 FBcl0655598
RP003179684 FBcl0655599
RP003149945 FBcl0655600
RP003003383 FBcl0655601
RP003349999 FBcl0655602
RP003613340 FBcl0655603
RP003350713 FBcl0655604
RP003525760 FBcl0655605

3 Exons

DB identifier Symbol
FBgn0011762:1 DNApol-alpha50:1
FBgn0011762:2 DNApol-alpha50:2
FBgn0011762:3 DNApol-alpha50:3

1 Transcripts

DB identifier Gene
FBtr0076603 DNApol-alpha50

2 UTRs

Class DB identifier
Organism . Name
FivePrimeUTR FBtr0076603-5-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0076603-3-prime-utr Drosophila melanogaster

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2 Cross References

Identifier
Source . Name

Subject . Primary Identifier
38942 NCBI Entrez Gene identifiers FBgn0011762
64360 BioGRID FBgn0011762

11 Data Sets

Name URL
FlyBase data set for Drosophila melanogaster  
Swiss-Prot data set http://ca.expasy.org/sprot
Drosophila 12 Genomes Consortium homology  
GenomeRNAi data set  
TreeFam data set  
Panther data set  
IntAct interactions data set  
BioGRID interaction data set http://www.thebiogrid.org/downloads.php
GO Annotation from FlyBase  
FlyBase fasta data set for Drosophila melanogaster  
Drosophila Cell Line and Developmental Stage Gene and Exon Scores  

55 Expression Scores


Gene . Primary Identifier

Submission . Title

Cell Line . Name

Developmental Stage . Name
Score
FBgn0011762 Drosophila Cell Line and Developmental Stage Gene and Exon Scores CME L1 237.0
FBgn0011762 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Sg4 126.0
FBgn0011762 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD11 89.0
FBgn0011762 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD20-c2 152.0
FBgn0011762 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD20-c5 165.0
FBgn0011762 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Kc167 364.0
FBgn0011762 Drosophila Cell Line and Developmental Stage Gene and Exon Scores GM2 40.0
FBgn0011762 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S2-DRSC 268.0
FBgn0011762 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S2R+ 140.0
FBgn0011762 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S1 128.0
FBgn0011762 Drosophila Cell Line and Developmental Stage Gene and Exon Scores 1182-4H 155.0
FBgn0011762 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD16-c3 310.0
FBgn0011762 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD32 113.0
FBgn0011762 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD17-c3 301.0
FBgn0011762 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD8 275.0
FBgn0011762 Drosophila Cell Line and Developmental Stage Gene and Exon Scores CME W1 Cl.8+ 77.0
FBgn0011762 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD9 114.0
FBgn0011762 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmBG1-c1 156.0
FBgn0011762 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD21 194.0
FBgn0011762 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD4-c1 70.0
FBgn0011762 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmBG3-c2 145.0
FBgn0011762 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S3 380.0
FBgn0011762 Drosophila Cell Line and Developmental Stage Gene and Exon Scores CME W2 90.0
FBgn0011762 Drosophila Cell Line and Developmental Stage Gene and Exon Scores mbn2 63.0
FBgn0011762 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmBG2-c2 217.0
FBgn0011762 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 0-2 h 1275.0
FBgn0011762 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 2-4 h 658.0
FBgn0011762 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 4-6 h 708.0
FBgn0011762 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 6-8 h 352.0
FBgn0011762 Drosophila Cell Line and Developmental Stage Gene and Exon Scores emb 8-10h 147.0

2 Introns

DB identifier
Organism . Name
intron_FBgn0011762:1_FBgn0011762:2 Drosophila melanogaster
intron_FBgn0011762:2_FBgn0011762:3 Drosophila melanogaster

15 RNAi Results

Screen Gene Phenotype Score Conditions PubMed ID
Lipid storage DNApol-alpha50 none 1.790529064   19067489
Lipid storage DNApol-alpha50 none 0.052971451   19067489
Cell size and cell-cycle regulation (1) DNApol-alpha50 none sp   16496002
Cell size and cell-cycle regulation (1) DNApol-alpha50 none sp   16496002
Combinatorial effect with methyl methanesulphonate (2) DNApol-alpha50 none sp   19543366
Muscle morphogenesis and function (1) DNApol-alpha50 Lethal np   20220848
Heat nociception (1) DNApol-alpha50 Developmentally lethal -0.14   21074052
Heart development and function (1) DNApol-alpha50 Adult lethal 0.5   20371351
Heart development and function (2) DNApol-alpha50 Decreased viability 9.66   20371351
Serratia marcescens infection (1) DNApol-alpha50 none 0.351351351351351   19520911
Notch pathway regulation (4) DNApol-alpha50 Completely lethal (before pupal) sp   19363474
Self-renewal and differentiation in neural stem cells DNApol-alpha50 GFP aggregates number, GFP aggregates size, neuroblast larger cell size, neuroblast cell shape, ganglion mother cell shorter lineages, neuroblast underproliferation, lethal sp   21549331
Adiposity regulation (1) DNApol-alpha50 none 0.033   20074523
Hippo pathway regulation DNApol-alpha50 none -0.64   23263283
Glycosylation regulation (1) DNApol-alpha50 none sp   21203496

0 Submissions