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Gene : grp D. melanogaster

DB identifier  ? FBgn0261278 Secondary Identifier  ? CG17161
Name  ? grapes Source  FlyBase
  • synonyms:
  • last empress,
  • FBgn0261278,
  • 1C,
  • lemp,
  • Grp/DChk1,
  • Protein kinase-like 36A,
  • FBgn0011598,
  • CHK1/Grapes,
  • lethal (2) k15102,
  • FBgn0040478,
  • Grp,
  • CHK1,
  • FBgn0004632,
  • Grapes,
  • grps,
  • Dchk1,
  • Pk36A,
  • l(2)k15102,
  • FBgn0069054,
  • DmChk1,
  • grp(chk),
  • FBan0017161,
  • Checkpoint kinase 1,
  • FBgn0021840,
  • FBgn0024213,
  • Pk?1,
  • CG17161

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103 Alleles

DB identifier Symbol Allele Class Organism
FBal0195704 grp[t29.8]   Drosophila melanogaster
FBal0284057 grp[GUS.cBa]   Drosophila melanogaster
FBal0179591 grp[DG02808]   Drosophila melanogaster
FBal0179590 grp[DG25208]   Drosophila melanogaster
FBal0211988 grp[CB04894]   Drosophila melanogaster
FBal0283167 grp[C115]   Drosophila melanogaster
FBal0179584 grp[d07543]   Drosophila melanogaster
FBal0179580 grp[f06887]   Drosophila melanogaster
FBal0179581 grp[f03577]   Drosophila melanogaster
FBal0179586 grp[c05746]   Drosophila melanogaster
FBal0179589 grp[c01229]   Drosophila melanogaster
FBal0179588 grp[c01254]   Drosophila melanogaster
FBal0175654 grp[GS2133]   Drosophila melanogaster
FBal0159176 grp[EY11888]   Drosophila melanogaster
FBal0130245 grp[EP2343]   Drosophila melanogaster
FBal0179585 grp[d02837]   Drosophila melanogaster
FBal0179582 grp[f03358]   Drosophila melanogaster
FBal0179583 grp[e02195]   Drosophila melanogaster
FBal0179587 grp[c04899]   Drosophila melanogaster
FBal0159175 grp[e00087]   Drosophila melanogaster
FBal0159177 grp[EY09600]   Drosophila melanogaster
FBal0151879 grp[BG02170]   Drosophila melanogaster
FBal0151878 grp[L36B]   Drosophila melanogaster
FBal0151880 grp[BG01786]   Drosophila melanogaster
FBal0151881 grp[BG00940]   Drosophila melanogaster
FBal0119242 grp[EP587]   Drosophila melanogaster
FBal0130241 grp[EP921]   Drosophila melanogaster
FBal0130248 grp[EP1106]   Drosophila melanogaster
FBal0130244 grp[EP2566]   Drosophila melanogaster
FBal0130246 grp[EP2196]   Drosophila melanogaster

93 Clones

Secondary Identifier DB identifier
DPiM_LD42896 FBcl0740951
AT19361 FBcl0040947
AT16290 FBcl0040957
AT27359 FBcl0040961
AT14317 FBcl0041005
AT13792 FBcl0041053
bs04f04 FBcl0057129
CK00051 FBcl0060487
EK302308 FBcl0094376
EK138203 FBcl0096918
EK175031 FBcl0096950
EK140860 FBcl0096980
EK258954 FBcl0097192
EK009312 FBcl0098322
EK144504 FBcl0098352
EK163310 FBcl0098382
GM13457 FBcl0147214
LD09905 FBcl0156860
LD14845 FBcl0156863
LD20111 FBcl0156881
LD39588 FBcl0170736
LD26974 FBcl0170737
LD27088 FBcl0170745
LD42288 FBcl0170752
LD42896 FBcl0170754
LD26850 FBcl0170759
LP05380 FBcl0185392
RE50325 FBcl0214740
RE47618 FBcl0214742
RE45702 FBcl0214753

10 Exons

DB identifier Symbol
FBgn0261278:1 grp:1
FBgn0261278:2 grp:2
FBgn0261278:4 grp:4
FBgn0261278:5 grp:5
FBgn0261278:7 grp:7
FBgn0261278:8 grp:8
FBgn0261278:9 grp:9
FBgn0261278:10 grp:10
FBgn0261278:3 grp:3
FBgn0261278:6 grp:6

5 Transcripts

DB identifier Gene
FBtr0339514 grp
FBtr0080885 grp
FBtr0080884 grp
FBtr0080886 grp
FBtr0100459 grp

10 UTRs

Class DB identifier
Organism . Name
FivePrimeUTR FBtr0080885-5-prime-utr Drosophila melanogaster
FivePrimeUTR FBtr0080884-5-prime-utr Drosophila melanogaster
FivePrimeUTR FBtr0080886-5-prime-utr Drosophila melanogaster
FivePrimeUTR FBtr0100459-5-prime-utr Drosophila melanogaster
FivePrimeUTR FBtr0339514-5-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0080885-3-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0080884-3-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0080886-3-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0100459-3-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0339514-3-prime-utr Drosophila melanogaster

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4 Cross References

Identifier
Source . Name

Subject . Primary Identifier
3355106 NCBI Entrez Gene identifiers FBgn0261278
34993 NCBI Entrez Gene identifiers FBgn0261278
39824 NCBI Entrez Gene identifiers FBgn0261278
61001 BioGRID FBgn0261278

10 Data Sets

Name URL
FlyBase data set for Drosophila melanogaster  
Swiss-Prot data set http://ca.expasy.org/sprot
Drosophila 12 Genomes Consortium homology  
GenomeRNAi data set  
TreeFam data set  
Panther data set  
IntAct interactions data set  
BioGRID interaction data set http://www.thebiogrid.org/downloads.php
GO Annotation from FlyBase  
FlyBase fasta data set for Drosophila melanogaster  

0 Expression Scores

11 Introns

DB identifier
Organism . Name
intron_FBgn0261278:1_FBgn0261278:4 Drosophila melanogaster
intron_FBgn0261278:4_FBgn0261278:7 Drosophila melanogaster
intron_FBgn0261278:7_FBgn0261278:8 Drosophila melanogaster
intron_FBgn0261278:8_FBgn0261278:9 Drosophila melanogaster
intron_FBgn0261278:9_FBgn0261278:10 Drosophila melanogaster
intron_FBgn0261278:1_FBgn0261278:2 Drosophila melanogaster
intron_FBgn0261278:2_FBgn0261278:4 Drosophila melanogaster
intron_FBgn0261278:4_FBgn0261278:5 Drosophila melanogaster
intron_FBgn0261278:5_FBgn0261278:7 Drosophila melanogaster
intron_FBgn0261278:3_FBgn0261278:4 Drosophila melanogaster
intron_FBgn0261278:6_FBgn0261278:7 Drosophila melanogaster

34 RNAi Results

Screen Gene Phenotype Score Conditions PubMed ID
Lipid storage grp none -0.849285196   19067489
Lipid storage grp none -1.857041942   19067489
Cell cycle regulation (1) grp Spindle defects, chromosome alignment defects, lagging chromatids sp   15616552
Cell cycle regulation (2) grp none np   15616552
Cell size and cell-cycle regulation (1) grp none sp   16496002
Cell size and cell-cycle regulation (1) grp Increased G1 DNA content, decreased G2 DNA content sp   16496002
Cell size and cell-cycle regulation (1) grp none sp   16496002
Cell size and cell-cycle regulation (1) grp none sp   16496002
Combinatorial effect with methyl methanesulphonate (2) grp none sp   19543366
Muscle morphogenesis and function (1) grp Locomotion defect np   20220848
Heat nociception (1) grp none -1.17   21074052
Heart development and function (1) grp none 1   20371351
Serratia marcescens infection (1) grp none 1.68817204301075   19520911
Notch pathway regulation (4) grp none 0   19363474
PGN-induced dJNK phosphorylation grp Decreased P-JNK protein expression with PGN -2.19 15 min PGN induction 19893628
G2-M DNA damage checkpoint regulation (2) grp Increased histone H3 phosphorylation with bleocin 72.77 with bleocin 21205937
G2-M DNA damage checkpoint regulation (2) grp Increased histone H3 phosphorylation with doxorubicin 59.72 with doxorubicin 21205937
G2-M DNA damage checkpoint regulation (2) grp Increased histone H3 phosphorylation with etoposide 68.03 with etoposide 21205937
G2-M DNA damage checkpoint regulation (2) grp Increased histone H3 phosphorylation after X-ray exposure 68.96 X-ray exposure 21205937
Adiposity regulation (1) grp none -0.098   20074523
Blood cell homeostasis regulation (1) grp none np   20540764
Blood cell homeostasis regulation (2) grp Increased melanotic mass formation np   20540764
Blood cell homeostasis regulation (3) grp none 0   20540764
Blood cell homeostasis regulation (4) grp none 0   20540764
Blood cell homeostasis regulation (5) grp none 0   20540764
Actin organization and cell morphology (1) grp none np   19265526
Actin organization and cell morphology (2) grp none np   19265526
Actin organization and cell morphology (3) grp none np   19265526
Actin organization and cell morphology (4) grp none np   19265526
Actin organization and cell morphology (5) grp none np   19265526

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