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Gene : ial D. melanogaster

DB identifier  ? FBgn0024227 Secondary Identifier  ? CG6620
Name  ? IplI-aurora-like kinase Source  FlyBase
  • synonyms:
  • DmAuroraB,
  • AuroraB,
  • Aur B,
  • ial/AurB,
  • Aurora-B,
  • ABK,
  • dAurora B,
  • DmAIRK2,
  • Aurora,
  • AurB,
  • DmAurB,
  • IAL1,
  • AURORA-like,
  • CG6620,
  • Aurora B kinase,
  • FBan0006620,
  • FBgn0024227,
  • IAL,
  • Aurora B

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13 Alleles

DB identifier Symbol Allele Class Organism
FBal0286514 ial[Scer\UAS.ORF]   Drosophila melanogaster
FBal0286515 ial[Scer\UAS.ORF.T:Ivir\HA1]   Drosophila melanogaster
FBal0277757 ial[T:Avic\GFP-EGFP]   Drosophila melanogaster
FBal0144232 ial[dsRNA.cLa]   Drosophila melanogaster
FBal0121724 ial[a.cGa]   Drosophila melanogaster
FBal0121723 ial[cGa]   Drosophila melanogaster
FBal0123814 ial[dsRNA.cAa]   Drosophila melanogaster
FBal0262675 ial[GL00202]   Drosophila melanogaster
FBal0288007 ial[Scer\UAS.P\T.T:Avic\GFP]   Drosophila melanogaster
FBal0239607 ial[JF03107]   Drosophila melanogaster
FBal0209718 ial[GD11982]   Drosophila melanogaster
FBal0238240 ial[KK112558]   Drosophila melanogaster
FBal0275213 ial[NIG.6620R]   Drosophila melanogaster

107 Clones

Secondary Identifier DB identifier
EK295419 FBcl0095966
EK173903 FBcl0096014
EK153946 FBcl0097046
GM07406 FBcl0142628
GM23320 FBcl0147297
LD07127 FBcl0162648
LD05274 FBcl0162649
LD39409 FBcl0178588
LP16341 FBcl0191599
RE41638 FBcl0238331
RE68313 FBcl0238332
SD15987 FBcl0288032
EC056310 FBcl0301158
EC054537 FBcl0301159
EC053988 FBcl0301160
EC051022 FBcl0301161
EC052508 FBcl0301162
EC053553 FBcl0301163
EC054534 FBcl0301164
192541 FBcl0400746
GM26516 FBcl0332238
GM26558 FBcl0332239
FGM306F12 FBcl0392556
194191 FBcl0400757
40222 FBcl0400762
84372 FBcl0400769
RP003492480 FBcl0600985
RP003124811 FBcl0600942
RP003368085 FBcl0600943
RP003575085 FBcl0600949

3 Exons

DB identifier Symbol
FBgn0024227:3 ial:3
FBgn0024227:2 ial:2
FBgn0024227:1 ial:1

1 Transcripts

DB identifier Gene
FBtr0080180 ial

2 UTRs

Class DB identifier
Organism . Name
FivePrimeUTR FBtr0080180-5-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0080180-3-prime-utr Drosophila melanogaster

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0 Pathways

2 Cross References

Identifier
Source . Name

Subject . Primary Identifier
34504 NCBI Entrez Gene identifiers FBgn0024227
60576 BioGRID FBgn0024227

11 Data Sets

Name URL
FlyBase data set for Drosophila melanogaster  
Swiss-Prot data set http://ca.expasy.org/sprot
Drosophila 12 Genomes Consortium homology  
GenomeRNAi data set  
TreeFam data set  
Panther data set  
IntAct interactions data set  
BioGRID interaction data set http://www.thebiogrid.org/downloads.php
GO Annotation from FlyBase  
FlyBase fasta data set for Drosophila melanogaster  
Drosophila Cell Line and Developmental Stage Gene and Exon Scores  

55 Expression Scores


Gene . Primary Identifier

Submission . Title

Cell Line . Name

Developmental Stage . Name
Score
FBgn0024227 Drosophila Cell Line and Developmental Stage Gene and Exon Scores CME L1 797.0
FBgn0024227 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Sg4 898.0
FBgn0024227 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD11 391.0
FBgn0024227 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD20-c2 493.0
FBgn0024227 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD20-c5 569.0
FBgn0024227 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Kc167 407.0
FBgn0024227 Drosophila Cell Line and Developmental Stage Gene and Exon Scores GM2 361.0
FBgn0024227 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S2-DRSC 607.0
FBgn0024227 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S2R+ 474.0
FBgn0024227 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S1 954.0
FBgn0024227 Drosophila Cell Line and Developmental Stage Gene and Exon Scores 1182-4H 656.0
FBgn0024227 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD16-c3 590.0
FBgn0024227 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD32 337.0
FBgn0024227 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD17-c3 690.0
FBgn0024227 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD8 463.0
FBgn0024227 Drosophila Cell Line and Developmental Stage Gene and Exon Scores CME W1 Cl.8+ 536.0
FBgn0024227 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD9 446.0
FBgn0024227 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmBG1-c1 344.0
FBgn0024227 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD21 572.0
FBgn0024227 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD4-c1 522.0
FBgn0024227 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmBG3-c2 315.0
FBgn0024227 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S3 647.0
FBgn0024227 Drosophila Cell Line and Developmental Stage Gene and Exon Scores CME W2 370.0
FBgn0024227 Drosophila Cell Line and Developmental Stage Gene and Exon Scores mbn2 354.0
FBgn0024227 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmBG2-c2 311.0
FBgn0024227 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 0-2 h 1030.0
FBgn0024227 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 2-4 h 1147.0
FBgn0024227 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 4-6 h 1482.0
FBgn0024227 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 6-8 h 1279.0
FBgn0024227 Drosophila Cell Line and Developmental Stage Gene and Exon Scores emb 8-10h 1006.0

2 Introns

DB identifier
Organism . Name
intron_FBgn0024227:3_FBgn0024227:2 Drosophila melanogaster
intron_FBgn0024227:2_FBgn0024227:1 Drosophila melanogaster

35 RNAi Results

Screen Gene Phenotype Score Conditions PubMed ID
Lipid storage ial none 0.638987493   19067489
Lipid storage ial none 0   19067489
Lipid storage ial none 0   19067489
Lipid storage ial none 0.037640898   19067489
Cell morphology ial Morphology np   14527345
Cell cycle regulation (1) ial Decreased cytokinetic index, centrosome defects, all mitotic defects, chromosome defects, polyploid cells sp   15616552
Cell cycle regulation (2) ial Increased number of polyploid cells np   15616552
Cytokinesis ial Multi-nucleate cells np   15380073
Cytokinesis regulation ial Binucleate cells with large, diffuse DNA strong   15547975
Imd pathway regulation ial Increased Dipt::lacZ protein expression after lipopolysaccharide stimulation 23   15221030
Cell size and cell-cycle regulation (1) ial Decreased G1 DNA content, increased G2 DNA content sp   16496002
Cell size and cell-cycle regulation (1) ial none sp   16496002
Cell size and cell-cycle regulation (1) ial none sp   16496002
Cell size and cell-cycle regulation (2) ial none 1.433   16496002
Cell size and cell-cycle regulation (3) ial none 462   16496002
Dendrite pattern formation ial none np   16547170
Mitosis ial Multipolar spindle np   17412918
Heat nociception (1) ial Increased noxious heat avoidance 1.67   21074052
Heat nociception (2) ial none 33.66666667   21074052
Heart development and function (1) ial none 1   20371351
Serratia marcescens infection (1) ial none -0.125   19520911
Notch pathway regulation (4) ial Notum malformation migration 8   19363474
Notch induced transcription ial none -1.2704 without Notch stimulation 20959007
Notch induced transcription ial Downregulation of Notch pathway after Notch stimulation -4.2904 N(delta)ecn Notch stimulation 20959007
Notch induced transcription ial Downregulation of Notch pathway after Notch stimulation -2.2659 N(delta)ecn Notch stimulation 20959007
Self-renewal and differentiation in neural stem cells ial GFP aggregates number, GFP aggregates size, neuroblast abnormally large cell size, neuroblast larger cell size, neuroblast cell shape, ganglion mother cell shorter lineages, extremely increased neuroblast cell size without neuroblast loss, neuroblast unde sp   21549331
Adiposity regulation (1) ial none 1.498   20074523
Actin organization and cell morphology (1) ial Altered cell morphology np   19265526
Actin organization and cell morphology (2) ial Altered cell morphology np   19265526
Actin organization and cell morphology (3) ial Altered cell morphology np   19265526

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