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Gene : His3.3B D. melanogaster

DB identifier  ? FBgn0004828 Secondary Identifier  ? CG8989
Name  ? Histone H3.3B Source  FlyBase
  • synonyms:
  • His3.3,
  • CG8989,
  • histone variant H3.3,
  • FBtr0071347,
  • HistoneH3,
  • histone variant 3.3,
  • anon-EST:fe1B6,
  • FBtr0071346,
  • PH3,
  • CG8989-PB,
  • histone H3.3,
  • CG8989-RA,
  • CG8989-PC,
  • FBgn0004828,
  • anon-fast-evolving-1B6,
  • dH3.3B,
  • FBpp0071281,
  • FBtr0071345,
  • FBan0008989,
  • HisH3-3Q,
  • FBgn0025266,
  • FBpp0071282,
  • FBpp0071280,
  • H3.3,
  • CG8989-RC,
  • CG8989-RB,
  • Histone H3-3Q,
  • CG8989-PA,
  • H3.3B

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23 Alleles

DB identifier Symbol Allele Class Organism
FBal0248471 His3.3B[KO]   Drosophila melanogaster
FBal0248472 His3.3B[T:Zzzz\FLAG]   Drosophila melanogaster
FBal0248473 His3.3B[Scer\FRT.K4A.T:Ivir\HA1]   Drosophila melanogaster
FBal0248474 His3.3B[K4A.T:Ivir\HA1]   Drosophila melanogaster
FBal0248475 His3.3B[Scer\FRT.K9A.T:Ivir\HA1]   Drosophila melanogaster
FBal0248476 His3.3B[K9A.T:Ivir\HA1]   Drosophila melanogaster
FBal0248477 His3.3B[Scer\FRT.H3.2.T:Ivir\HA1]   Drosophila melanogaster
FBal0248478 His3.3B[H3.2.T:Ivir\HA1]   Drosophila melanogaster
FBal0248479 His3.3B[Scer\FRT.T:Ivir\HA1]   Drosophila melanogaster
FBal0248480 His3.3B[T:Ivir\HA1]   Drosophila melanogaster
FBal0281067 His3.3B[+tHa]   Drosophila melanogaster
FBal0248481 His3.3B[Scer\FRT.cHa]   Drosophila melanogaster
FBal0281068 His3.3B[K4R]   Drosophila melanogaster
FBal0281069 His3.3B[K4A]   Drosophila melanogaster
FBal0248482 His3.3B[cHa]   Drosophila melanogaster
FBal0183306 His3.3B[d04051]   Drosophila melanogaster
FBal0131005 His3.3B[EP1598]   Drosophila melanogaster
FBal0263145 His3.3B[HMS00148]   Drosophila melanogaster
FBal0207293 His3.3B[GD4749]   Drosophila melanogaster
FBal0242712 His3.3B[0]   Drosophila melanogaster
FBal0226942 His3.3B[NP4000]   Drosophila melanogaster
FBal0226943 His3.3B[GG01697]   Drosophila melanogaster
FBal0276241 His3.3B[NIG.8989R]   Drosophila melanogaster

363 Clones

Secondary Identifier DB identifier
80158 FBcl0411061
RP003653866 FBcl0484078
ESG011a.E7.1_B01 FBcl0013825
bs85e08 FBcl0048433
bs62c07 FBcl0048447
EC38565 FBcl0062823
EC13065 FBcl0062827
EC37656 FBcl0062861
EP05064 FBcl0076277
EP11960 FBcl0076289
EP10859 FBcl0076309
EP05444 FBcl0077121
EP08650 FBcl0077551
EN11521 FBcl0092429
EN06261 FBcl0092435
EK249523 FBcl0115826
EK262055 FBcl0115830
EK302250 FBcl0115834
EK158853 FBcl0115846
EK162126 FBcl0115850
EK210729 FBcl0115854
EK253011 FBcl0115882
EK305205 FBcl0115886
EK250716 FBcl0115890
EK250728 FBcl0115894
EK216211 FBcl0115898
EK109822 FBcl0115902
EK043421 FBcl0115906
EK084618 FBcl0115912
EK295751 FBcl0115918

6 Exons

DB identifier Symbol
FBgn0004828:6 His3.3B:6
FBgn0004828:3 His3.3B:3
FBgn0004828:2 His3.3B:2
FBgn0004828:5 His3.3B:5
FBgn0004828:4 His3.3B:4
FBgn0004828:1 His3.3B:1

4 Transcripts

DB identifier Gene
FBtr0071347 His3.3B
FBtr0071345 His3.3B
FBtr0340343 His3.3B
FBtr0071346 His3.3B

8 UTRs

Class DB identifier
Organism . Name
FivePrimeUTR FBtr0071345-5-prime-utr Drosophila melanogaster
FivePrimeUTR FBtr0071347-5-prime-utr Drosophila melanogaster
FivePrimeUTR FBtr0071346-5-prime-utr Drosophila melanogaster
FivePrimeUTR FBtr0340343-5-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0071345-3-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0071347-3-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0071346-3-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0340343-3-prime-utr Drosophila melanogaster

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2 Cross References

Identifier
Source . Name

Subject . Primary Identifier
31848 NCBI Entrez Gene identifiers FBgn0004828
58303 BioGRID FBgn0004828

11 Data Sets

Name URL
FlyBase data set for Drosophila melanogaster  
Swiss-Prot data set http://ca.expasy.org/sprot
Drosophila 12 Genomes Consortium homology  
GenomeRNAi data set  
TreeFam data set  
Panther data set  
IntAct interactions data set  
BioGRID interaction data set http://www.thebiogrid.org/downloads.php
GO Annotation from FlyBase  
FlyBase fasta data set for Drosophila melanogaster  
Drosophila Cell Line and Developmental Stage Gene and Exon Scores  

55 Expression Scores


Gene . Primary Identifier

Submission . Title

Cell Line . Name

Developmental Stage . Name
Score
FBgn0004828 Drosophila Cell Line and Developmental Stage Gene and Exon Scores CME L1 10506.0
FBgn0004828 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Sg4 10550.0
FBgn0004828 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD11 8562.0
FBgn0004828 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD20-c2 10057.0
FBgn0004828 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD20-c5 9113.0
FBgn0004828 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Kc167 13361.0
FBgn0004828 Drosophila Cell Line and Developmental Stage Gene and Exon Scores GM2 11561.0
FBgn0004828 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S2-DRSC 8429.0
FBgn0004828 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S2R+ 8345.0
FBgn0004828 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S1 4769.0
FBgn0004828 Drosophila Cell Line and Developmental Stage Gene and Exon Scores 1182-4H 8423.0
FBgn0004828 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD16-c3 9029.0
FBgn0004828 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD32 11265.0
FBgn0004828 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD17-c3 10974.0
FBgn0004828 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD8 17948.0
FBgn0004828 Drosophila Cell Line and Developmental Stage Gene and Exon Scores CME W1 Cl.8+ 8676.0
FBgn0004828 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD9 12302.0
FBgn0004828 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmBG1-c1 8072.0
FBgn0004828 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD21 12431.0
FBgn0004828 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD4-c1 7726.0
FBgn0004828 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmBG3-c2 10364.0
FBgn0004828 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S3 7470.0
FBgn0004828 Drosophila Cell Line and Developmental Stage Gene and Exon Scores CME W2 6069.0
FBgn0004828 Drosophila Cell Line and Developmental Stage Gene and Exon Scores mbn2 5969.0
FBgn0004828 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmBG2-c2 4438.0
FBgn0004828 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 0-2 h 9103.0
FBgn0004828 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 2-4 h 8662.0
FBgn0004828 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 4-6 h 9337.0
FBgn0004828 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 6-8 h 8479.0
FBgn0004828 Drosophila Cell Line and Developmental Stage Gene and Exon Scores emb 8-10h 10790.0

5 Introns

DB identifier
Organism . Name
intron_FBgn0004828:5_FBgn0004828:3 Drosophila melanogaster
intron_FBgn0004828:3_FBgn0004828:2 Drosophila melanogaster
intron_FBgn0004828:6_FBgn0004828:3 Drosophila melanogaster
intron_FBgn0004828:3_FBgn0004828:1 Drosophila melanogaster
intron_FBgn0004828:4_FBgn0004828:3 Drosophila melanogaster

23 RNAi Results

Screen Gene Phenotype Score Conditions PubMed ID
Lipid storage His3.3B none 1.453813273   19067489
Lipid storage His3.3B none 0.68332957   19067489
Lipid storage His3.3B none -0.825102759   19067489
ERK signaling His3.3B ERK activation reduced weak   17086199
Cell size and cell-cycle regulation (1) His3.3B none sp   16496002
Muscle morphogenesis and function (1) His3.3B none np   20220848
Heat nociception (1) His3.3B none -1.17   21074052
Heart development and function (1) His3.3B none 1   20371351
Serratia marcescens infection (1) His3.3B none -0.852941176470588   19520911
Notch pathway regulation (4) His3.3B none 0   19363474
Notch induced transcription His3.3B none 1.6449 without Notch stimulation 20959007
Notch induced transcription His3.3B none -1.9605 N(delta)ecn Notch stimulation 20959007
Notch induced transcription His3.3B Downregulation of Notch pathway after Notch stimulation -4.1139 N(delta)ecn Notch stimulation 20959007
Adiposity regulation (1) His3.3B none 0.016   20074523
Blood cell homeostasis regulation (1) His3.3B none np   20540764
Blood cell homeostasis regulation (2) His3.3B none np   20540764
RTK-Ras-ERK pathway regulation (1) His3.3B none -0.45 10 minutes EGF stimulation 22028469
RTK-Ras-ERK pathway regulation (1) His3.3B none -0.73 0 minutes EGF stimulation 22028469
RTK-Ras-ERK pathway regulation (2) His3.3B none 0.06 30 minutes sSpitz stimulation 22028469
RTK-Ras-ERK pathway regulation (2) His3.3B none 0.15 10 minutes sSpitz stimulation 22028469
Hippo pathway regulation His3.3B none 0.47   23263283
Srp/Lz-induced transcriptional activation His3.3B Increased Srp/Lz-induced transcription 6.03   20368357
Glycosylation regulation (1) His3.3B none sp   21203496

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