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Gene : Mhc D. melanogaster

DB identifier  ? FBgn0264695 Secondary Identifier  ? CG17927
Name  ? Myosin heavy chain Source  FlyBase
  • synonyms:
  • l(2)M66,
  • indirect flight muscle (2) RU2,
  • Myosin Heavy Chain-PF,
  • Shrunken thorax,
  • FBgn0002741,
  • Muscle myosin heavy chain,
  • chain,
  • muscle specific myosin II,
  • FBgn0021948,
  • DroMII,
  • Bsh,
  • FBgn0028640,
  • Not-upheld,
  • Myosin rod protein,
  • sarcomeric myosin heavy-chain,
  • myosin heavy-chain,
  • Indirect flight muscle (2) RU1,
  • DROMHC,
  • Muscle Myosin,
  • CG17927,
  • Ifm(2)2,
  • MyHC,
  • muscle Myosin II heavy chain,
  • Nup,
  • DmMHC,
  • Mhc36B,
  • l(2)k10423,
  • sMHC,
  • FBgn0020400,
  • Stp,
  • l(2)36Ae,
  • beta-myosin heavy chain,
  • Shrunken-thorax,
  • Dm II,
  • Myo,
  • Sht,
  • Ifm(2)RU1,
  • mMHC,
  • FBgn0086783,
  • muscle myosin II,
  • FBgn0010142,
  • FBgn0264695,
  • muscle myosin-II,
  • Samba,
  • MRP,
  • myosin heavy-chain protein,
  • myosin heavy,
  • FBan0017927,
  • Stuckup,
  • ifm(2)RU2,
  • MHC,
  • FBgn0028724,
  • Myosin Heavy Chain,
  • Myosin,
  • heavy chain

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135 Alleles

DB identifier Symbol Allele Class Organism
FBal0267917 Mhc[Emb.Act88F.T:Zzzz\His6,T:Zzzz\TEV.CS]   Drosophila melanogaster
FBal0212257 Mhc[YD0783]   Drosophila melanogaster
FBal0217344 Mhc[Ifm(2)RU1-2]   Drosophila melanogaster
FBal0217345 Mhc[Ifm(2)RU1-3]   Drosophila melanogaster
FBal0217346 Mhc[Ifm(2)RU1-4]   Drosophila melanogaster
FBal0269038 Mhc[unspecified]   Drosophila melanogaster
FBal0101377 Mhc[ifm(2)RU2-2]   Drosophila melanogaster
FBal0101376 Mhc[ifm(2)RU2-3]   Drosophila melanogaster
FBal0101375 Mhc[ifm(2)RU2-4]   Drosophila melanogaster
FBal0101374 Mhc[ifm(2)RU2-5]   Drosophila melanogaster
FBal0101373 Mhc[ifm(2)RU2-6]   Drosophila melanogaster
FBal0101372 Mhc[ifm(2)RU2-7]   Drosophila melanogaster
FBal0101371 Mhc[ifm(2)RU2-8]   Drosophila melanogaster
FBal0101370 Mhc[ifm(2)RU2-9]   Drosophila melanogaster
FBal0217347 Mhc[ifm(2)RU2-10]   Drosophila melanogaster
FBal0217348 Mhc[ifm(2)RU2-11]   Drosophila melanogaster
FBal0217349 Mhc[ifm(2)RU2-12]   Drosophila melanogaster
FBal0217350 Mhc[ifm(2)RU2-13]   Drosophila melanogaster
FBal0217351 Mhc[ifm(2)RU2-14]   Drosophila melanogaster
FBal0217352 Mhc[ifm(2)RU2-15]   Drosophila melanogaster
FBal0220560 Mhc[JF02069]   Drosophila melanogaster
FBal0212161 Mhc[PT1]   Drosophila melanogaster
FBal0212162 Mhc[FO]   Drosophila melanogaster
FBal0182725 Mhc[LA00447]   Drosophila melanogaster
FBal0264130 Mhc[MI03941]   Drosophila melanogaster
FBal0156241 Mhc[Wee-P26]   Drosophila melanogaster
FBal0182724 Mhc[d07814]   Drosophila melanogaster
FBal0064206 Mhc[k10423]   Drosophila melanogaster
FBal0260721 Mhc[+t11.7]   Drosophila melanogaster
FBal0260722 Mhc[+t12.4]   Drosophila melanogaster

276 Clones

Secondary Identifier DB identifier
71391 FBcl0431431
CK01.3A.G12 FBcl0431438
CK01.105A.G6 FBcl0431451
CK01.82A.G1 FBcl0431453
CK01.2D.C11 FBcl0431527
61822 FBcl0431544
CK01.130D.E7 FBcl0431566
CK01.57D.E12 FBcl0431599
bs29h10 FBcl0057207
EP09434 FBcl0088235
EP13107 FBcl0088237
EP09612 FBcl0088251
EP10336 FBcl0088261
EP09809 FBcl0088267
EP16362 FBcl0088269
EP10946 FBcl0088329
EP11743 FBcl0088345
EK108330 FBcl0093214
EK025028 FBcl0095088
EK291527 FBcl0095122
EK171638 FBcl0095140
EK302348 FBcl0095158
EK109950 FBcl0095212
EK290206 FBcl0095262
EK057307 FBcl0095654
EK045952 FBcl0095722
EK103158 FBcl0095738
EK184720 FBcl0095758
EK164209 FBcl0095776
EK216158 FBcl0095796

36 Exons

DB identifier Symbol
FBgn0264695:1 Mhc:1
FBgn0264695:7 Mhc:7
FBgn0264695:9 Mhc:9
FBgn0264695:11 Mhc:11
FBgn0264695:12 Mhc:12
FBgn0264695:13 Mhc:13
FBgn0264695:15 Mhc:15
FBgn0264695:17 Mhc:17
FBgn0264695:19 Mhc:19
FBgn0264695:21 Mhc:21
FBgn0264695:24 Mhc:24
FBgn0264695:27 Mhc:27
FBgn0264695:28 Mhc:28
FBgn0264695:29 Mhc:29
FBgn0264695:31 Mhc:31
FBgn0264695:32 Mhc:32
FBgn0264695:33 Mhc:33
FBgn0264695:36 Mhc:36
FBgn0264695:2 Mhc:2
FBgn0264695:14 Mhc:14
FBgn0264695:25 Mhc:25
FBgn0264695:10 Mhc:10
FBgn0264695:16 Mhc:16
FBgn0264695:18 Mhc:18
FBgn0264695:22 Mhc:22
FBgn0264695:30 Mhc:30
FBgn0264695:34 Mhc:34
FBgn0264695:35 Mhc:35
FBgn0264695:26 Mhc:26
FBgn0264695:20 Mhc:20

20 Transcripts

DB identifier Gene
FBtr0307494 Mhc
FBtr0307496 Mhc
FBtr0301829 Mhc
FBtr0080895 Mhc
FBtr0080896 Mhc
FBtr0080903 Mhc
FBtr0080897 Mhc
FBtr0080898 Mhc
FBtr0080899 Mhc
FBtr0080900 Mhc
FBtr0080901 Mhc
FBtr0080902 Mhc
FBtr0307492 Mhc
FBtr0301827 Mhc
FBtr0080905 Mhc
FBtr0307493 Mhc
FBtr0080906 Mhc
FBtr0301828 Mhc
FBtr0080907 Mhc
FBtr0307495 Mhc

40 UTRs

Class DB identifier
Organism . Name
FivePrimeUTR FBtr0307493-5-prime-utr Drosophila melanogaster
FivePrimeUTR FBtr0080898-5-prime-utr Drosophila melanogaster
FivePrimeUTR FBtr0080900-5-prime-utr Drosophila melanogaster
FivePrimeUTR FBtr0080906-5-prime-utr Drosophila melanogaster
FivePrimeUTR FBtr0301829-5-prime-utr Drosophila melanogaster
FivePrimeUTR FBtr0080907-5-prime-utr Drosophila melanogaster
FivePrimeUTR FBtr0080896-5-prime-utr Drosophila melanogaster
FivePrimeUTR FBtr0301827-5-prime-utr Drosophila melanogaster
FivePrimeUTR FBtr0080895-5-prime-utr Drosophila melanogaster
FivePrimeUTR FBtr0080905-5-prime-utr Drosophila melanogaster
FivePrimeUTR FBtr0080903-5-prime-utr Drosophila melanogaster
FivePrimeUTR FBtr0080897-5-prime-utr Drosophila melanogaster
FivePrimeUTR FBtr0307492-5-prime-utr Drosophila melanogaster
FivePrimeUTR FBtr0080901-5-prime-utr Drosophila melanogaster
FivePrimeUTR FBtr0307496-5-prime-utr Drosophila melanogaster
FivePrimeUTR FBtr0301828-5-prime-utr Drosophila melanogaster
FivePrimeUTR FBtr0307495-5-prime-utr Drosophila melanogaster
FivePrimeUTR FBtr0080902-5-prime-utr Drosophila melanogaster
FivePrimeUTR FBtr0307494-5-prime-utr Drosophila melanogaster
FivePrimeUTR FBtr0080899-5-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0307493-3-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0080898-3-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0080900-3-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0080906-3-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0301829-3-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0080907-3-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0080896-3-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0301827-3-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0080895-3-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0080905-3-prime-utr Drosophila melanogaster

Interactions

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Other

0 Pathways

2 Cross References

Identifier
Source . Name

Subject . Primary Identifier
35007 NCBI Entrez Gene identifiers FBgn0264695
61014 BioGRID FBgn0264695

10 Data Sets

Name URL
FlyBase data set for Drosophila melanogaster  
Swiss-Prot data set http://ca.expasy.org/sprot
Drosophila 12 Genomes Consortium homology  
GenomeRNAi data set  
TreeFam data set  
Panther data set  
IntAct interactions data set  
BioGRID interaction data set http://www.thebiogrid.org/downloads.php
GO Annotation from FlyBase  
FlyBase fasta data set for Drosophila melanogaster  

0 Expression Scores

47 Introns

DB identifier
Organism . Name
intron_FBgn0264695:5_FBgn0264695:7 Drosophila melanogaster
intron_FBgn0264695:7_FBgn0264695:9 Drosophila melanogaster
intron_FBgn0264695:9_FBgn0264695:11 Drosophila melanogaster
intron_FBgn0264695:11_FBgn0264695:12 Drosophila melanogaster
intron_FBgn0264695:12_FBgn0264695:13 Drosophila melanogaster
intron_FBgn0264695:13_FBgn0264695:15 Drosophila melanogaster
intron_FBgn0264695:15_FBgn0264695:17 Drosophila melanogaster
intron_FBgn0264695:17_FBgn0264695:19 Drosophila melanogaster
intron_FBgn0264695:19_FBgn0264695:21 Drosophila melanogaster
intron_FBgn0264695:21_FBgn0264695:26 Drosophila melanogaster
intron_FBgn0264695:26_FBgn0264695:27 Drosophila melanogaster
intron_FBgn0264695:27_FBgn0264695:28 Drosophila melanogaster
intron_FBgn0264695:28_FBgn0264695:29 Drosophila melanogaster
intron_FBgn0264695:29_FBgn0264695:30 Drosophila melanogaster
intron_FBgn0264695:30_FBgn0264695:32 Drosophila melanogaster
intron_FBgn0264695:32_FBgn0264695:33 Drosophila melanogaster
intron_FBgn0264695:33_FBgn0264695:36 Drosophila melanogaster
intron_FBgn0264695:6_FBgn0264695:7 Drosophila melanogaster
intron_FBgn0264695:7_FBgn0264695:10 Drosophila melanogaster
intron_FBgn0264695:10_FBgn0264695:11 Drosophila melanogaster
intron_FBgn0264695:13_FBgn0264695:14 Drosophila melanogaster
intron_FBgn0264695:14_FBgn0264695:17 Drosophila melanogaster
intron_FBgn0264695:21_FBgn0264695:25 Drosophila melanogaster
intron_FBgn0264695:25_FBgn0264695:27 Drosophila melanogaster
intron_FBgn0264695:29_FBgn0264695:31 Drosophila melanogaster
intron_FBgn0264695:31_FBgn0264695:32 Drosophila melanogaster
intron_FBgn0264695:33_FBgn0264695:35 Drosophila melanogaster
intron_FBgn0264695:35_FBgn0264695:36 Drosophila melanogaster
intron_FBgn0264695:2_FBgn0264695:7 Drosophila melanogaster
intron_FBgn0264695:13_FBgn0264695:16 Drosophila melanogaster

24 RNAi Results

Screen Gene Phenotype Score Conditions PubMed ID
Lipid storage Mhc Increased lipid droplet area 5.122224603   19067489
Lipid storage Mhc Increased lipid droplet area 4.81915369   19067489
Cell size and cell-cycle regulation (1) Mhc none sp   16496002
Cell size and cell-cycle regulation (1) Mhc none sp   16496002
Muscle morphogenesis and function (1) Mhc Lethal np   20220848
Muscle morphogenesis and function (2) Mhc Wing posture / locomotion / ability to fly defect or lethal / semi-lethal np   20220848
Muscle morphogenesis and function (3) Mhc Spotty (discontinuous) Z-line np   20220848
Heat nociception (1) Mhc Developmentally lethal -1.17   21074052
Heart development and function (1) Mhc none 0.8   20371351
Heart development and function (2) Mhc Decreased viability 4.86   20371351
Serratia marcescens infection (1) Mhc none 0.106060606060606   19520911
Notch pathway regulation (4) Mhc none 0   19363474
Muscle assembly and maintenance Mhc Muscles spread, actin and myosin filaments lack striation np   18359903
Adiposity regulation (1) Mhc none -0.141   20074523
RTK-Ras-ERK pathway regulation (1) Mhc Increased ERK phosphorylation after EGF stimulation 1.78 0 minutes EGF stimulation 22028469
RTK-Ras-ERK pathway regulation (1) Mhc Decreased ERK phosphorylation after EGF stimulation -2.49 10 minutes EGF stimulation 22028469
RTK-Ras-ERK pathway regulation (2) Mhc none -0.73 10 minutes sSpitz stimulation 22028469
RTK-Ras-ERK pathway regulation (2) Mhc none 1.07 30 minutes sSpitz stimulation 22028469
Hippo pathway regulation Mhc none 1.07   23263283
Muscle development and maintenance Mhc Embryo lethal sp  
Muscle development and maintenance Mhc Embryo lethal sp  
Muscle maintenance Mhc Climbing defect sp  
Muscle maintenance Mhc Climbing defect sp  
Glycosylation regulation (1) Mhc none sp   21203496

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