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Gene : Prosbeta3 D. melanogaster

DB identifier  ? FBgn0026380 Secondary Identifier  ? CG11981
Name  ? Proteasome beta3 subunit Source  FlyBase
  • synonyms:
  • 20S proteasome,
  • 20S proteasome beta3 subunit,
  • beta3,
  • CG11981,
  • FBgn0026380,
  • Beta-3,
  • 11981,
  • FBan0011981,
  • Prosbeta3,
  • Pros beta3

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7 Alleles

DB identifier Symbol Allele Class Organism
FBal0268431 Prosbeta3[NIG.11981R]   Drosophila melanogaster
FBal0263182 Prosbeta3[HMS00187]   Drosophila melanogaster
FBal0286988 Prosbeta3[Scer\UAS.ORF]   Drosophila melanogaster
FBal0286989 Prosbeta3[Scer\UAS.ORF.T:Ivir\HA1]   Drosophila melanogaster
FBal0241390 Prosbeta3[G4206]   Drosophila melanogaster
FBal0208130 Prosbeta3[GD7449]   Drosophila melanogaster
FBal0235329 Prosbeta3[KK108041]   Drosophila melanogaster

43 Clones

Secondary Identifier DB identifier
ESG0115b.B21_D03 FBcl0001887
EK128913 FBcl0027120
bs66a08 FBcl0057911
bs33d06 FBcl0057913
bs65a03 FBcl0057921
EC35122 FBcl0073075
EC40102 FBcl0073077
EC40702 FBcl0073079
EN07463 FBcl0101779
GH08012 FBcl0110025
LD16402 FBcl0153522
LD41659 FBcl0166458
LD35829 FBcl0166469
LD35422 FBcl0166479
LD30164 FBcl0166828
LP04281 FBcl0182256
LP17836 FBcl0182268
LP19041 FBcl0182406
LP11760 FBcl0182455
RE34021 FBcl0202234
RE55792 FBcl0202259
RE45567 FBcl0203058
RE60955 FBcl0203064
RE17209 FBcl0203106
RE23919 FBcl0203118
RE64411 FBcl0203147
RE47935 FBcl0203158
RE23671 FBcl0203164
RE47923 FBcl0203165
RE18523 FBcl0203193

1 Exons

DB identifier Symbol
FBgn0026380:1 Prosbeta3:1

1 Transcripts

DB identifier Gene
FBtr0082010 Prosbeta3

2 UTRs

Class DB identifier
Organism . Name
FivePrimeUTR FBtr0082010-5-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0082010-3-prime-utr Drosophila melanogaster

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74 Pathways

2 Cross References

Identifier
Source . Name

Subject . Primary Identifier
41079 NCBI Entrez Gene identifiers FBgn0026380
66247 BioGRID FBgn0026380

11 Data Sets

Name URL
FlyBase data set for Drosophila melanogaster  
Swiss-Prot data set http://ca.expasy.org/sprot
Drosophila 12 Genomes Consortium homology  
GenomeRNAi data set  
TreeFam data set  
Panther data set  
IntAct interactions data set  
BioGRID interaction data set http://www.thebiogrid.org/downloads.php
GO Annotation from FlyBase  
FlyBase fasta data set for Drosophila melanogaster  
Drosophila Cell Line and Developmental Stage Gene and Exon Scores  

55 Expression Scores


Gene . Primary Identifier

Submission . Title

Cell Line . Name

Developmental Stage . Name
Score
FBgn0026380 Drosophila Cell Line and Developmental Stage Gene and Exon Scores CME L1 1262.0
FBgn0026380 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Sg4 1571.0
FBgn0026380 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD11 1381.0
FBgn0026380 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD20-c2 1785.0
FBgn0026380 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD20-c5 1464.0
FBgn0026380 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Kc167 2064.0
FBgn0026380 Drosophila Cell Line and Developmental Stage Gene and Exon Scores GM2 1861.0
FBgn0026380 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S2-DRSC 1112.0
FBgn0026380 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S2R+ 852.0
FBgn0026380 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S1 2076.0
FBgn0026380 Drosophila Cell Line and Developmental Stage Gene and Exon Scores 1182-4H 1561.0
FBgn0026380 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD16-c3 1155.0
FBgn0026380 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD32 1083.0
FBgn0026380 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD17-c3 1492.0
FBgn0026380 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD8 1786.0
FBgn0026380 Drosophila Cell Line and Developmental Stage Gene and Exon Scores CME W1 Cl.8+ 1505.0
FBgn0026380 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD9 1600.0
FBgn0026380 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmBG1-c1 1712.0
FBgn0026380 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD21 1112.0
FBgn0026380 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD4-c1 1278.0
FBgn0026380 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmBG3-c2 1060.0
FBgn0026380 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S3 1458.0
FBgn0026380 Drosophila Cell Line and Developmental Stage Gene and Exon Scores CME W2 1203.0
FBgn0026380 Drosophila Cell Line and Developmental Stage Gene and Exon Scores mbn2 1348.0
FBgn0026380 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmBG2-c2 2194.0
FBgn0026380 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 0-2 h 3730.0
FBgn0026380 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 2-4 h 3323.0
FBgn0026380 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 4-6 h 1574.0
FBgn0026380 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 6-8 h 822.0
FBgn0026380 Drosophila Cell Line and Developmental Stage Gene and Exon Scores emb 8-10h 934.0

0 Introns

37 RNAi Results

Screen Gene Phenotype Score Conditions PubMed ID
Lipid storage Prosbeta3 none -0.716580408   19067489
Lipid storage Prosbeta3 none 0.631953868   19067489
ERK signaling Prosbeta3 ERK activation reduced weak   17086199
Intracellular Listeria monocytogenes infection Prosbeta3 Decreased GFP protein expression strong   16020693
Hedgehog signaling Prosbeta3 Decreased Hedgehog reporter activity -3.85   16311596
Constitutive protein secretion and Golgi organization (1) Prosbeta3 Decreased horseradish peroxidase protein expression sp   16452979
Cell size and cell-cycle regulation (1) Prosbeta3 Decreased G1 DNA content sp   16496002
Cell size and cell-cycle regulation (2) Prosbeta3 none 1.41   16496002
Cell size and cell-cycle regulation (3) Prosbeta3 none 447   16496002
Cell size and cell-cycle regulation (4) Prosbeta3 none below threshold   16496002
Candida albicans phagocytosis (1) Prosbeta3 none np   16336044
Influenza replication Prosbeta3 Decreased Influenza replication -0.2/-4.15   18615016
Combinatorial effect with methyl methanesulphonate (2) Prosbeta3 Synthetic lethal with methyl methanesulphonate sp   19543366
Mutant human huntingtin aggregation Prosbeta3 Decreased mutant human huntingtin aggregation <= -2   19789644
Muscle morphogenesis and function (1) Prosbeta3 Lethal np   20220848
Heat nociception (1) Prosbeta3 Developmentally lethal 0   21074052
Heart development and function (1) Prosbeta3 Embryonic lethal or no offspring 0   20371351
Serratia marcescens infection (1) Prosbeta3 none -0.2125   19520911
Notch pathway regulation (4) Prosbeta3 Completely lethal (before pupal) sp   19363474
PGN-induced dJNK phosphorylation Prosbeta3 Increased P-JNK protein expression with PGN 3.12 60 min PGN induction 19893628
Hh pathway regulation Prosbeta3 Downregulation of Hh pathway -0.423160002087999   17903264
Hh pathway regulation Prosbeta3 Downregulation of Hh pathway -0.51146180192205   17903264
Self-renewal and differentiation in neural stem cells Prosbeta3 Neuroblast smaller cell size, ganglion mother cell shorter lineages, neuroblasts smaller, neuroblast underproliferation, lethal sp   21549331
Adiposity regulation (1) Prosbeta3 Decreased triglyceride expression -0.697   20074523
Adiposity regulation (2) Prosbeta3 Lethal or developmental delay d/l   20074523
Adiposity regulation (3) Prosbeta3 Lethal or developmental delay d/l   20074523
Adiposity regulation (4) Prosbeta3 Lethal or developmental delay d/l   20074523
Adiposity regulation (5) Prosbeta3 Lethal or developmental delay d/l   20074523
Blood cell homeostasis regulation (1) Prosbeta3 none np   20540764
Blood cell homeostasis regulation (2) Prosbeta3 none np   20540764

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