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Gene : Rac1 D. melanogaster

DB identifier  ? FBgn0010333 Secondary Identifier  ? CG2248
Name  ? Rac1 Source  FlyBase
  • synonyms:
  • DmRAC,
  • Rac GTPase,
  • Rac-1,
  • Rac,
  • DmRAC1,
  • RAC1,
  • Rac3,
  • DRacA,
  • FBgn0014012,
  • GTPase Rac1,
  • DRac,
  • P40792,
  • DRac1,
  • Drac1a,
  • D-Rac,
  • FBgn0010333,
  • D-Rac1,
  • 2248,
  • RacA,
  • FBan0002248,
  • Dm Rac1,
  • CG2248,
  • D-Rac 1

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49 Alleles

DB identifier Symbol Allele Class Organism
FBal0210963 Rac1[dsRNA.cSb]   Drosophila melanogaster
FBal0176036 Rac1[dsRNA.UTR.cIa]   Drosophila melanogaster
FBal0240325 Rac1[JF02813]   Drosophila melanogaster
FBal0182024 Rac1[e03245]   Drosophila melanogaster
FBal0147582 Rac1[EY05848]   Drosophila melanogaster
FBal0288673 Rac1[T:Avic\GFP]   Drosophila melanogaster
FBal0042719 Rac1[V12.hs]   Drosophila melanogaster
FBal0042718 Rac1[hs.PH]   Drosophila melanogaster
FBal0042717 Rac1[N17.hs]   Drosophila melanogaster
FBal0094009 Rac1[GMR.PN]   Drosophila melanogaster
FBal0105125 Rac1[V12.hs.sev]   Drosophila melanogaster
FBal0117667 Rac1[GMR.PNe]   Drosophila melanogaster
FBal0118385 Rac1[hs.sev]   Drosophila melanogaster
FBal0135839 Rac1[+t3.6]   Drosophila melanogaster
FBal0176035 Rac1[dsRNA.cIa]   Drosophila melanogaster
FBal0135835 Rac1[J11] loss of function allele Drosophila melanogaster
FBal0176038 Rac1[DA.MtnA]   Drosophila melanogaster
FBal0150663 Rac1[dsRNA.cSa]   Drosophila melanogaster
FBal0135838 Rac1[Df]   Drosophila melanogaster
FBal0094625 Rac1[N17.cCa]   Drosophila melanogaster
FBal0135836 Rac1[J10] loss of function allele, hypomorphic allele - genetic evidence Drosophila melanogaster
FBal0147580 Rac1[dsRNA.cCa]   Drosophila melanogaster
FBal0156000 Rac1[dsRNA.cKa]   Drosophila melanogaster
FBal0135834 Rac1[J6] loss of function allele Drosophila melanogaster
FBal0094623 Rac1[wt.cCa]   Drosophila melanogaster
FBal0182023 Rac1[unspecified]   Drosophila melanogaster
FBal0094624 Rac1[V12.cCa]   Drosophila melanogaster
FBal0135837 Rac1[F37A.Scer\UAS.T:Hsap\MYC]   Drosophila melanogaster
FBal0038992 Rac1[L89.Scer\UAS]   Drosophila melanogaster
FBal0176037 Rac1[MtnA.T:Zzzz\FLAG]   Drosophila melanogaster

100 Clones

Secondary Identifier DB identifier
DPiM_LD34217 FBcl0741208
EK058127 FBcl0036128
UUGC0401 FBcl0001069
EK209745 FBcl0033922
EK220556 FBcl0036228
EK126151 FBcl0033942
EK163320 FBcl0033962
EK213061 FBcl0034018
EK186902 FBcl0034036
EK121202 FBcl0034052
EK237326 FBcl0034090
EK237840 FBcl0034110
EK209712 FBcl0034130
EK202238 FBcl0034152
EK108453 FBcl0036362
EK123239 FBcl0034170
EK034942 FBcl0034270
EK171536 FBcl0036436
EK109433 FBcl0034310
EK136018 FBcl0034330
EK252846 FBcl0034354
EK132342 FBcl0034372
EK104733 FBcl0036458
EK054149 FBcl0034558
EK045553 FBcl0035722
EK156035 FBcl0033602
EN11847 FBcl0096871
EN00564 FBcl0096873
EN10625 FBcl0096877
GM04495 FBcl0141836

2 Exons

DB identifier Symbol
FBgn0010333:2 Rac1:2
FBgn0010333:1 Rac1:1

2 Transcripts

DB identifier Gene
FBtr0072730 Rac1
FBtr0331868 Rac1

4 UTRs

Class DB identifier
Organism . Name
FivePrimeUTR FBtr0072730-5-prime-utr Drosophila melanogaster
FivePrimeUTR FBtr0331868-5-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0072730-3-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0331868-3-prime-utr Drosophila melanogaster

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2 Cross References

Identifier
Source . Name

Subject . Primary Identifier
38146 NCBI Entrez Gene identifiers FBgn0010333
63689 BioGRID FBgn0010333

11 Data Sets

Name URL
FlyBase data set for Drosophila melanogaster  
Swiss-Prot data set http://ca.expasy.org/sprot
Drosophila 12 Genomes Consortium homology  
GenomeRNAi data set  
TreeFam data set  
Panther data set  
IntAct interactions data set  
BioGRID interaction data set http://www.thebiogrid.org/downloads.php
GO Annotation from FlyBase  
FlyBase fasta data set for Drosophila melanogaster  
Drosophila Cell Line and Developmental Stage Gene and Exon Scores  

55 Expression Scores


Gene . Primary Identifier

Submission . Title

Cell Line . Name

Developmental Stage . Name
Score
FBgn0010333 Drosophila Cell Line and Developmental Stage Gene and Exon Scores CME L1 3043.0
FBgn0010333 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Sg4 3024.0
FBgn0010333 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD11 1471.0
FBgn0010333 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD20-c2 3096.0
FBgn0010333 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD20-c5 3879.0
FBgn0010333 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Kc167 3449.0
FBgn0010333 Drosophila Cell Line and Developmental Stage Gene and Exon Scores GM2 2430.0
FBgn0010333 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S2-DRSC 2226.0
FBgn0010333 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S2R+ 1970.0
FBgn0010333 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S1 2281.0
FBgn0010333 Drosophila Cell Line and Developmental Stage Gene and Exon Scores 1182-4H 2567.0
FBgn0010333 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD16-c3 1699.0
FBgn0010333 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD32 2201.0
FBgn0010333 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD17-c3 2923.0
FBgn0010333 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD8 1913.0
FBgn0010333 Drosophila Cell Line and Developmental Stage Gene and Exon Scores CME W1 Cl.8+ 1710.0
FBgn0010333 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD9 2263.0
FBgn0010333 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmBG1-c1 1216.0
FBgn0010333 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD21 2514.0
FBgn0010333 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD4-c1 2107.0
FBgn0010333 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmBG3-c2 3515.0
FBgn0010333 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S3 2709.0
FBgn0010333 Drosophila Cell Line and Developmental Stage Gene and Exon Scores CME W2 1873.0
FBgn0010333 Drosophila Cell Line and Developmental Stage Gene and Exon Scores mbn2 1868.0
FBgn0010333 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmBG2-c2 1080.0
FBgn0010333 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 0-2 h 2497.0
FBgn0010333 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 2-4 h 2594.0
FBgn0010333 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 4-6 h 1729.0
FBgn0010333 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 6-8 h 1530.0
FBgn0010333 Drosophila Cell Line and Developmental Stage Gene and Exon Scores emb 8-10h 2007.0

0 Introns

22 RNAi Results

Screen Gene Phenotype Score Conditions PubMed ID
Lipid storage Rac1 none -0.051086244   19067489
Lipid storage Rac1 none 1.100789989   19067489
ERK signaling Rac1 ERK activation reduced moderate   17086199
Cell size and cell-cycle regulation (1) Rac1 none sp   16496002
Candida albicans phagocytosis (1) Rac1 Decreased Candida albicans phagocytosis np   16336044
Candida albicans phagocytosis (2) Rac1 Decreased Escherichia coli phagocytosis 28   16336044
Candida albicans phagocytosis (3) Rac1 Decreased latex beads phagocytosis 41   16336044
Brucella melitensis infection Rac1 Decreased Brucella melitensis infection 53.7   18654626
C. trachomatis infection Rac1 C. trachomatis infection down np   18369471
Combinatorial effect with methyl methanesulphonate (2) Rac1 Synthetic lethal with methyl methanesulphonate sp   19543366
Heat nociception (1) Rac1 none 0.81   21074052
Heart development and function (1) Rac1 none 1   20371351
Heart development and function (2) Rac1 Decreased viability 3.14   20371351
Serratia marcescens infection (1) Rac1 none 0.453125   19520911
Adiposity regulation (1) Rac1 none -0.514   20074523
S2 cell spreading Rac1 Stellate morphology on Con A surface sp   21041442
RTK-Ras-ERK pathway regulation (1) Rac1 Decreased ERK phosphorylation after EGF stimulation -1.59 10 minutes EGF stimulation 22028469
RTK-Ras-ERK pathway regulation (1) Rac1 none -0.82 0 minutes EGF stimulation 22028469
RTK-Ras-ERK pathway regulation (2) Rac1 none -0.52 10 minutes sSpitz stimulation 22028469
RTK-Ras-ERK pathway regulation (2) Rac1 none -0.99 30 minutes sSpitz stimulation 22028469
Hippo pathway regulation Rac1 none 0.64   23263283
Glycosylation regulation (1) Rac1 Lethal np   21203496

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