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Gene : Rac2 D. melanogaster

DB identifier  ? FBgn0014011 Secondary Identifier  ? CG8556
Name  ? Rac2 Source  FlyBase
  • synonyms:
  • Rac-2,
  • FBgn0014011,
  • CG8556,
  • D-Rac2,
  • P48554,
  • Rac1b,
  • rac2,
  • Rac GTPase,
  • D-Rac 2,
  • DRac2,
  • Rac,
  • DRacB,
  • Drac1b,
  • Rac1,
  • FBan0008556,
  • DmRAC2,
  • RacB

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23 Alleles

DB identifier Symbol Allele Class Organism
FBal0210962 Rac2[dsRNA.cSb]   Drosophila melanogaster
FBal0176034 Rac2[dsRNA.UTR.cIa]   Drosophila melanogaster
FBal0280259 Rac2[Scer\UAS.cEa]   Drosophila melanogaster
FBal0280260 Rac2[Scer\UAS.T:Hsap\MYC]   Drosophila melanogaster
FBal0182022 Rac2[d01612]   Drosophila melanogaster
FBal0152263 Rac2[EP3226]   Drosophila melanogaster
FBal0152262 Rac2[EP3227]   Drosophila melanogaster
FBal0134176 Rac2[EP3118]   Drosophila melanogaster
FBal0137387 Rac2[KG05681b]   Drosophila melanogaster
FBal0288674 Rac2[T:Avic\GFP]   Drosophila melanogaster
FBal0135831 Rac2[Delta] loss of function allele Drosophila melanogaster
FBal0155999 Rac2[314]   Drosophila melanogaster
FBal0094008 Rac2[GMR.PN]   Drosophila melanogaster
FBal0147579 Rac2[dsRNA.cCa]   Drosophila melanogaster
FBal0150662 Rac2[dsRNA.cSa]   Drosophila melanogaster
FBal0155998 Rac2[dsRNA.cKa]   Drosophila melanogaster
FBal0240400 Rac2[unspecified]   Drosophila melanogaster
FBal0194993 Rac2[GS10622]   Drosophila melanogaster
FBal0208221 Rac2[GD13964]   Drosophila melanogaster
FBal0208222 Rac2[GD17536]   Drosophila melanogaster
FBal0219750 Rac2[Scer\UAS.cARa]   Drosophila melanogaster
FBal0219277 Rac2[DG19808]   Drosophila melanogaster
FBal0276054 Rac2[NIG.8556R]   Drosophila melanogaster

47 Clones

Secondary Identifier DB identifier
UUGC0409 FBcl0001231
ESG015d.B21_A12 FBcl0008441
EN10023 FBcl0095233
EN05919 FBcl0095235
EN00511 FBcl0095241
EN08348 FBcl0095247
EN08427 FBcl0095253
EN05410 FBcl0095269
EN12758 FBcl0095273
EN09355 FBcl0095281
EK048146 FBcl0119402
EK064053 FBcl0119412
EK255222 FBcl0120184
EK072957 FBcl0120556
EK050905 FBcl0120646
EK070949 FBcl0121062
GM13874 FBcl0145793
RE49878 FBcl0203078
RE06962 FBcl0203122
RE45441 FBcl0203126
RE57408 FBcl0203130
RE47153 FBcl0203173
SD05313 FBcl0282782
SD25203 FBcl0282786
SD24681 FBcl0282787
Dmel_dig_017604_0659_1811 FBcl0381201
Dmel_neb_010158_0564_2371 FBcl0381202
FGM224G07 FBcl0391006
524778 FBcl0477616
527869 FBcl0477579

2 Exons

DB identifier Symbol
FBgn0014011:2 Rac2:2
FBgn0014011:1 Rac2:1

2 Transcripts

DB identifier Gene
FBtr0076867 Rac2
FBtr0332800 Rac2

4 UTRs

Class DB identifier
Organism . Name
FivePrimeUTR FBtr0076867-5-prime-utr Drosophila melanogaster
FivePrimeUTR FBtr0332800-5-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0076867-3-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0332800-3-prime-utr Drosophila melanogaster

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2 Cross References

Identifier
Source . Name

Subject . Primary Identifier
38831 NCBI Entrez Gene identifiers FBgn0014011
64269 BioGRID FBgn0014011

11 Data Sets

Name URL
FlyBase data set for Drosophila melanogaster  
Swiss-Prot data set http://ca.expasy.org/sprot
Drosophila 12 Genomes Consortium homology  
GenomeRNAi data set  
TreeFam data set  
Panther data set  
IntAct interactions data set  
BioGRID interaction data set http://www.thebiogrid.org/downloads.php
GO Annotation from FlyBase  
FlyBase fasta data set for Drosophila melanogaster  
Drosophila Cell Line and Developmental Stage Gene and Exon Scores  

55 Expression Scores


Gene . Primary Identifier

Submission . Title

Cell Line . Name

Developmental Stage . Name
Score
FBgn0014011 Drosophila Cell Line and Developmental Stage Gene and Exon Scores CME L1 932.0
FBgn0014011 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Sg4 626.0
FBgn0014011 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD11 574.0
FBgn0014011 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD20-c2 728.0
FBgn0014011 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD20-c5 905.0
FBgn0014011 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Kc167 435.0
FBgn0014011 Drosophila Cell Line and Developmental Stage Gene and Exon Scores GM2 1526.0
FBgn0014011 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S2-DRSC 622.0
FBgn0014011 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S2R+ 556.0
FBgn0014011 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S1 826.0
FBgn0014011 Drosophila Cell Line and Developmental Stage Gene and Exon Scores 1182-4H 1384.0
FBgn0014011 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD16-c3 577.0
FBgn0014011 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD32 1076.0
FBgn0014011 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD17-c3 1203.0
FBgn0014011 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD8 826.0
FBgn0014011 Drosophila Cell Line and Developmental Stage Gene and Exon Scores CME W1 Cl.8+ 552.0
FBgn0014011 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD9 983.0
FBgn0014011 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmBG1-c1 1217.0
FBgn0014011 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD21 1239.0
FBgn0014011 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD4-c1 1291.0
FBgn0014011 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmBG3-c2 839.0
FBgn0014011 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S3 547.0
FBgn0014011 Drosophila Cell Line and Developmental Stage Gene and Exon Scores CME W2 845.0
FBgn0014011 Drosophila Cell Line and Developmental Stage Gene and Exon Scores mbn2 866.0
FBgn0014011 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmBG2-c2 362.0
FBgn0014011 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 0-2 h 508.0
FBgn0014011 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 2-4 h 603.0
FBgn0014011 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 4-6 h 901.0
FBgn0014011 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 6-8 h 690.0
FBgn0014011 Drosophila Cell Line and Developmental Stage Gene and Exon Scores emb 8-10h 888.0

0 Introns

40 RNAi Results

Screen Gene Phenotype Score Conditions PubMed ID
Lipid storage Rac2 none 0.966856115   19067489
Lipid storage Rac2 none -1.036268422   19067489
Neural outgrowth Rac2 Lamellar structures np   18604272
ERK signaling Rac2 ERK activation reduced strong   17086199
Cell morphology Rac2 Morphology np   14527345
Actin morphology Rac2 Perturbed formation of actin-based protrusions np   14588242
Imd pathway regulation Rac2 Increased Dipt::lacZ protein expression after lipopolysaccharide stimulation 20   15221030
Mycobacterial infection (1) - M. fortuitum infection Rac2 Decreased M. fortuitum intracellular infection 7.4 measurement after 3 days 16020694
Mycobacterial infection (2) - E. coli phagocytosis Rac2 Decreased E. coli phagocytosis np   16020694
Cell size and cell-cycle regulation (1) Rac2 none sp   16496002
Candida albicans phagocytosis (1) Rac2 Decreased Candida albicans phagocytosis np   16336044
Candida albicans phagocytosis (2) Rac2 Decreased Escherichia coli phagocytosis 32   16336044
Candida albicans phagocytosis (3) Rac2 Decreased latex beads phagocytosis 42   16336044
Brucella melitensis infection Rac2 Decreased Brucella melitensis infection 49.52   18654626
Combinatorial effect with methyl methanesulphonate (2) Rac2 none sp   19543366
Muscle morphogenesis and function (1) Rac2 Lethal np   20220848
Heat nociception (1) Rac2 none 1.56   21074052
Heat nociception (1) Rac2 none -0.79   21074052
Heat nociception (1) Rac2 none 1.26   21074052
Heart development and function (1) Rac2 none 1   20371351
Heart development and function (1) Rac2 none 1   20371351
Heart development and function (2) Rac2 none 2.36   20371351
Serratia marcescens infection (1) Rac2 none -0.466666666666666   19520911
Serratia marcescens infection (1) Rac2 none 0.774509803921568   19520911
Notch pathway regulation (4) Rac2 Loss of bristles, notum malformation death, lateral inhibition sp   19363474
Notch pathway regulation (4) Rac2 Completely lethal (pupal) sp   19363474
Notch pathway regulation (5) Rac2 none np   19363474
Notch pathway regulation (7) Rac2 Lethal np   19363474
PGN-induced dJNK phosphorylation Rac2 Increased P-JNK protein expression with PGN 3.93 15 min PGN induction 19893628
Adiposity regulation (1) Rac2 none -0.806   20074523

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