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Gene : chico D. melanogaster

DB identifier  ? FBgn0024248 Secondary Identifier  ? CG5686
Name  ? chico Source  FlyBase
  • synonyms:
  • FBgn0024248,
  • chic,
  • fs(2)4,
  • FBgn0014169,
  • flipper,
  • BcDNA:GH11263,
  • CHICO,
  • CG5686,
  • anon-WO0078940.4,
  • insulin-like receptor substrate,
  • FBgn0043508,
  • unnamed,
  • FBgn0043507,
  • IRS,
  • FBan0005686,
  • Insulin receptor substrate,
  • dIRS,
  • BcDNA.GH11263,
  • fs(2)ry4,
  • FBgn0013449,
  • IRS/chico,
  • anon-WO0078940.1,
  • FBgn0028483

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20 Alleles

DB identifier Symbol Allele Class Organism
FBal0266225 chico[GL00525]   Drosophila melanogaster
FBal0031303 chico[1] amorphic allele - molecular evidence, loss of function allele Drosophila melanogaster
FBal0137289 chico[KG00032]   Drosophila melanogaster
FBal0266460 chico[HMS01553]   Drosophila melanogaster
FBal0057437 chico[flp147E] amorphic allele - molecular evidence Drosophila melanogaster
FBal0057438 chico[+t10]   Drosophila melanogaster
FBal0098252 chico[+t8]   Drosophila melanogaster
FBal0103827 chico[41C]   Drosophila melanogaster
FBal0144393 chico[PTBmut]   Drosophila melanogaster
FBal0144394 chico[PI3Kmut]   Drosophila melanogaster
FBal0144395 chico[PHmut]   Drosophila melanogaster
FBal0144396 chico[Drkmut]   Drosophila melanogaster
FBal0103828 chico[170B]   Drosophila melanogaster
FBal0098251 chico[unspecified]   Drosophila melanogaster
FBal0268941 chico[Scer\UAS.cNa]   Drosophila melanogaster
FBal0117524 chico[dsRNA.cCa]   Drosophila melanogaster
FBal0239466 chico[JF02964]   Drosophila melanogaster
FBal0209248 chico[GD1402]   Drosophila melanogaster
FBal0222062 chico[5-SZ-3358]   Drosophila melanogaster
FBal0235030 chico[KK107581]   Drosophila melanogaster

50 Clones

Secondary Identifier DB identifier
EP07502 FBcl0086209
EK128530 FBcl0097842
EK185058 FBcl0097858
EK249103 FBcl0099806
EK185033 FBcl0099816
EK193041 FBcl0099932
GH02661 FBcl0135793
GH26846 FBcl0136319
GH07388 FBcl0136329
GH11263 FBcl0136335
GH20651 FBcl0136339
GH17407 FBcl0136341
GH21933 FBcl0136347
GM13655 FBcl0147409
GM20134 FBcl0147416
LD16868 FBcl0162712
LD36602 FBcl0178685
RE05565 FBcl0238204
RE05832 FBcl0238601
SD14654 FBcl0288477
SD07841 FBcl0288479
SD01062 FBcl0288486
EC053509 FBcl0301120
EC053534 FBcl0301121
CK01.1C.F8 FBcl0396292
CK01.8C.H8 FBcl0396325
64789 FBcl0396343
61513 FBcl0396352
61605 FBcl0396348
17158 FBcl0396375

11 Exons

DB identifier Symbol
FBgn0024248:10 chico:10
FBgn0024248:8 chico:8
FBgn0024248:7 chico:7
FBgn0024248:6 chico:6
FBgn0024248:5 chico:5
FBgn0024248:4 chico:4
FBgn0024248:3 chico:3
FBgn0024248:2 chico:2
FBgn0024248:1 chico:1
FBgn0024248:11 chico:11
FBgn0024248:9 chico:9

3 Transcripts

DB identifier Gene
FBtr0333412 chico
FBtr0080088 chico
FBtr0303904 chico

6 UTRs

Class DB identifier
Organism . Name
FivePrimeUTR FBtr0080088-5-prime-utr Drosophila melanogaster
FivePrimeUTR FBtr0303904-5-prime-utr Drosophila melanogaster
FivePrimeUTR FBtr0333412-5-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0080088-3-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0303904-3-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0333412-3-prime-utr Drosophila melanogaster

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2 Cross References

Identifier
Source . Name

Subject . Primary Identifier
64880 NCBI Entrez Gene identifiers FBgn0024248
72865 BioGRID FBgn0024248

11 Data Sets

Name URL
FlyBase data set for Drosophila melanogaster  
Swiss-Prot data set http://ca.expasy.org/sprot
Drosophila 12 Genomes Consortium homology  
GenomeRNAi data set  
TreeFam data set  
Panther data set  
IntAct interactions data set  
BioGRID interaction data set http://www.thebiogrid.org/downloads.php
GO Annotation from FlyBase  
FlyBase fasta data set for Drosophila melanogaster  
Drosophila Cell Line and Developmental Stage Gene and Exon Scores  

55 Expression Scores


Gene . Primary Identifier

Submission . Title

Cell Line . Name

Developmental Stage . Name
Score
FBgn0024248 Drosophila Cell Line and Developmental Stage Gene and Exon Scores CME L1 651.0
FBgn0024248 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Sg4 861.0
FBgn0024248 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD11 602.0
FBgn0024248 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD20-c2 550.0
FBgn0024248 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD20-c5 627.0
FBgn0024248 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Kc167 357.0
FBgn0024248 Drosophila Cell Line and Developmental Stage Gene and Exon Scores GM2 882.0
FBgn0024248 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S2-DRSC 626.0
FBgn0024248 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S2R+ 418.0
FBgn0024248 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S1 1074.0
FBgn0024248 Drosophila Cell Line and Developmental Stage Gene and Exon Scores 1182-4H 858.0
FBgn0024248 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD16-c3 604.0
FBgn0024248 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD32 902.0
FBgn0024248 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD17-c3 265.0
FBgn0024248 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD8 549.0
FBgn0024248 Drosophila Cell Line and Developmental Stage Gene and Exon Scores CME W1 Cl.8+ 647.0
FBgn0024248 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD9 833.0
FBgn0024248 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmBG1-c1 784.0
FBgn0024248 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD21 494.0
FBgn0024248 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD4-c1 528.0
FBgn0024248 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmBG3-c2 319.0
FBgn0024248 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S3 698.0
FBgn0024248 Drosophila Cell Line and Developmental Stage Gene and Exon Scores CME W2 806.0
FBgn0024248 Drosophila Cell Line and Developmental Stage Gene and Exon Scores mbn2 912.0
FBgn0024248 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmBG2-c2 960.0
FBgn0024248 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 0-2 h 947.0
FBgn0024248 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 2-4 h 772.0
FBgn0024248 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 4-6 h 836.0
FBgn0024248 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 6-8 h 630.0
FBgn0024248 Drosophila Cell Line and Developmental Stage Gene and Exon Scores emb 8-10h 696.0

11 Introns

DB identifier
Organism . Name
intron_FBgn0024248:10_FBgn0024248:8 Drosophila melanogaster
intron_FBgn0024248:8_FBgn0024248:7 Drosophila melanogaster
intron_FBgn0024248:7_FBgn0024248:6 Drosophila melanogaster
intron_FBgn0024248:6_FBgn0024248:5 Drosophila melanogaster
intron_FBgn0024248:5_FBgn0024248:4 Drosophila melanogaster
intron_FBgn0024248:4_FBgn0024248:3 Drosophila melanogaster
intron_FBgn0024248:3_FBgn0024248:2 Drosophila melanogaster
intron_FBgn0024248:2_FBgn0024248:1 Drosophila melanogaster
intron_FBgn0024248:11_FBgn0024248:8 Drosophila melanogaster
intron_FBgn0024248:10_FBgn0024248:9 Drosophila melanogaster
intron_FBgn0024248:9_FBgn0024248:8 Drosophila melanogaster

20 RNAi Results

Screen Gene Phenotype Score Conditions PubMed ID
Cell size regulation chico none -0.53   19216764
Lipid storage chico none -1.020325315   19067489
Lipid storage chico none -0.37886942   19067489
ERK signaling chico ERK activation increased strong   17086199
Cell size and cell-cycle regulation (1) chico none sp   16496002
Combinatorial effect with methyl methanesulphonate (2) chico none sp   19543366
Muscle morphogenesis and function (1) chico none np   20220848
Muscle morphogenesis and function (1) chico none np   20220848
Heat nociception (1) chico Lethal -0.88   21074052
Heat nociception (1) chico none 1.27   21074052
Heart development and function (1) chico none 1   20371351
Serratia marcescens infection (1) chico none 0.45679012345679   19520911
Notch pathway regulation (4) chico none 0   19363474
Notch pathway regulation (4) chico none 0   19363474
Adiposity regulation (1) chico none -0.035   20074523
RTK-Ras-ERK pathway regulation (1) chico none -0.69 10 minutes EGF stimulation 22028469
RTK-Ras-ERK pathway regulation (1) chico none -1.15 0 minutes EGF stimulation 22028469
RTK-Ras-ERK pathway regulation (2) chico none 0.01 10 minutes sSpitz stimulation 22028469
RTK-Ras-ERK pathway regulation (2) chico none 0.86 30 minutes sSpitz stimulation 22028469
Hippo pathway regulation chico none -0.76   23263283

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