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Gene : Rbf D. melanogaster

DB identifier  ? FBgn0015799 Secondary Identifier  ? CG7413
Name  ? Retinoblastoma-family protein Source  FlyBase
  • synonyms:
  • FBan0007413,
  • retinoblastoma-family protein,
  • retinoblastoma factor,
  • RBF,
  • RB,
  • retinoblastoma family protein 1,
  • pRb,
  • retinoblastoma-family homolog,
  • CG7413,
  • FBF,
  • retinoblastoma factor-1,
  • dRBF,
  • FBgn0015799,
  • RBF1,
  • Retinoblastoma,
  • EG:34F3.3,
  • Rb1

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63 Alleles

DB identifier Symbol Allele Class Organism
FBal0246607 Rbf[N.Scer\UAS.P\T.T:Disc\RFP-mCherry,T:SV5\V5]   Drosophila melanogaster
FBal0268194 Rbf[Scer\UAS.T:Zzzz\FLAG,T:Ivir\HA1]   Drosophila melanogaster
FBal0159929 Rbf[EY07209]   Drosophila melanogaster
FBal0095617 Rbf[38a]   Drosophila melanogaster
FBal0095619 Rbf[15a]   Drosophila melanogaster
FBal0095621 Rbf[120a]   Drosophila melanogaster
FBal0243347 Rbf[15aDelta]   Drosophila melanogaster
FBal0266576 Rbf[HMS03004]   Drosophila melanogaster
FBal0278745 Rbf[GL01293]   Drosophila melanogaster
FBal0181999 Rbf[dsRNA.cKa]   Drosophila melanogaster
FBal0048929 Rbf[GMR.PD]   Drosophila melanogaster
FBal0048928 Rbf[Act5C.PD]   Drosophila melanogaster
FBal0095616 Rbf[hs.PD]   Drosophila melanogaster
FBal0182001 Rbf[SLS-15]   Drosophila melanogaster
FBal0144640 Rbf[10.hs]   Drosophila melanogaster
FBal0144627 Rbf[596W.hs]   Drosophila melanogaster
FBal0144629 Rbf[555L.hs]   Drosophila melanogaster
FBal0144631 Rbf[30.hs]   Drosophila melanogaster
FBal0144634 Rbf[280.hs]   Drosophila melanogaster
FBal0144636 Rbf[280.GMR]   Drosophila melanogaster
FBal0155985 Rbf[t.Exel]   Drosophila melanogaster
FBal0144626 Rbf[M4.cXa]   Drosophila melanogaster
FBal0095620 Rbf[14] amorphic allele - genetic evidence Drosophila melanogaster
FBal0150655 Rbf[cFa]   Drosophila melanogaster
FBal0144635 Rbf[280.cXa]   Drosophila melanogaster
FBal0095622 Rbf[11]   Drosophila melanogaster
FBal0144632 Rbf[30.cXa]   Drosophila melanogaster
FBal0182002 Rbf[CAS-21]   Drosophila melanogaster
FBal0155986 Rbf[sls-15]   Drosophila melanogaster
FBal0144637 Rbf[223.cXa]   Drosophila melanogaster

219 Clones

Secondary Identifier DB identifier
DPiM_LD02906 FBcl0741647
AT28564 FBcl0013759
EK221322 FBcl0066016
EK093132 FBcl0066128
EK094463 FBcl0066136
EK205901 FBcl0066202
GH05946 FBcl0126593
GM24583 FBcl0144830
LD03488 FBcl0159542
LD02906 FBcl0159547
LD25209 FBcl0174460
LD45859 FBcl0174462
RE51195 FBcl0225412
RE21857 FBcl0225440
RE07437 FBcl0225444
RE20040 FBcl0225455
RE49295 FBcl0225461
RE48083 FBcl0225467
RE06540 FBcl0225488
SD10719 FBcl0279175
SD07569 FBcl0279176
CK01.122A.H11 FBcl0394706
RP003081530 FBcl0486435
RP003048962 FBcl0486353
RP003171340 FBcl0486354
RP003083877 FBcl0486355
RP003460266 FBcl0486356
RP003663232 FBcl0486357
RP003491234 FBcl0486358
RP003262329 FBcl0486359

8 Exons

DB identifier Symbol
FBgn0015799:4 Rbf:4
FBgn0015799:8 Rbf:8
FBgn0015799:7 Rbf:7
FBgn0015799:3 Rbf:3
FBgn0015799:2 Rbf:2
FBgn0015799:1 Rbf:1
FBgn0015799:6 Rbf:6
FBgn0015799:5 Rbf:5

1 Transcripts

DB identifier Gene
FBtr0070146 Rbf

2 UTRs

Class DB identifier
Organism . Name
FivePrimeUTR FBtr0070146-5-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0070146-3-prime-utr Drosophila melanogaster

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2 Cross References

Identifier
Source . Name

Subject . Primary Identifier
31027 NCBI Entrez Gene identifiers FBgn0015799
57595 BioGRID FBgn0015799

11 Data Sets

Name URL
FlyBase data set for Drosophila melanogaster  
Swiss-Prot data set http://ca.expasy.org/sprot
Drosophila 12 Genomes Consortium homology  
GenomeRNAi data set  
TreeFam data set  
Panther data set  
IntAct interactions data set  
BioGRID interaction data set http://www.thebiogrid.org/downloads.php
GO Annotation from FlyBase  
FlyBase fasta data set for Drosophila melanogaster  
Drosophila Cell Line and Developmental Stage Gene and Exon Scores  

55 Expression Scores


Gene . Primary Identifier

Submission . Title

Cell Line . Name

Developmental Stage . Name
Score
FBgn0015799 Drosophila Cell Line and Developmental Stage Gene and Exon Scores CME L1 1204.0
FBgn0015799 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Sg4 1000.0
FBgn0015799 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD11 836.0
FBgn0015799 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD20-c2 1089.0
FBgn0015799 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD20-c5 1254.0
FBgn0015799 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Kc167 270.0
FBgn0015799 Drosophila Cell Line and Developmental Stage Gene and Exon Scores GM2 733.0
FBgn0015799 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S2-DRSC 588.0
FBgn0015799 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S2R+ 506.0
FBgn0015799 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S1 1163.0
FBgn0015799 Drosophila Cell Line and Developmental Stage Gene and Exon Scores 1182-4H 1243.0
FBgn0015799 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD16-c3 404.0
FBgn0015799 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD32 1061.0
FBgn0015799 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD17-c3 558.0
FBgn0015799 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD8 1353.0
FBgn0015799 Drosophila Cell Line and Developmental Stage Gene and Exon Scores CME W1 Cl.8+ 867.0
FBgn0015799 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD9 1232.0
FBgn0015799 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmBG1-c1 653.0
FBgn0015799 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD21 1109.0
FBgn0015799 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD4-c1 1294.0
FBgn0015799 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmBG3-c2 1130.0
FBgn0015799 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S3 1104.0
FBgn0015799 Drosophila Cell Line and Developmental Stage Gene and Exon Scores CME W2 1267.0
FBgn0015799 Drosophila Cell Line and Developmental Stage Gene and Exon Scores mbn2 893.0
FBgn0015799 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmBG2-c2 1079.0
FBgn0015799 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 0-2 h 3512.0
FBgn0015799 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 2-4 h 779.0
FBgn0015799 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 4-6 h 1229.0
FBgn0015799 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 6-8 h 792.0
FBgn0015799 Drosophila Cell Line and Developmental Stage Gene and Exon Scores emb 8-10h 621.0

7 Introns

DB identifier
Organism . Name
intron_FBgn0015799:8_FBgn0015799:7 Drosophila melanogaster
intron_FBgn0015799:7_FBgn0015799:6 Drosophila melanogaster
intron_FBgn0015799:6_FBgn0015799:5 Drosophila melanogaster
intron_FBgn0015799:5_FBgn0015799:4 Drosophila melanogaster
intron_FBgn0015799:4_FBgn0015799:3 Drosophila melanogaster
intron_FBgn0015799:3_FBgn0015799:2 Drosophila melanogaster
intron_FBgn0015799:2_FBgn0015799:1 Drosophila melanogaster

21 RNAi Results

Screen Gene Phenotype Score Conditions PubMed ID
Lipid storage Rbf none -1.367094876   19067489
E2F signaling Rbf E2F signaling upregulated np   17517653
Cell size and cell-cycle regulation (1) Rbf Decreased G1 cell size sp   16496002
Cell size and cell-cycle regulation (1) Rbf Decreased G1 cell size sp   16496002
Cell size and cell-cycle regulation (2) Rbf none 1.243   16496002
Cell size and cell-cycle regulation (2) Rbf none 1.339   16496002
Cell size and cell-cycle regulation (3) Rbf none 465   16496002
Cell size and cell-cycle regulation (3) Rbf none 522   16496002
Cell size and cell-cycle regulation (4) Rbf Increased number of mitotic cells 0.8   16496002
Cell size and cell-cycle regulation (4) Rbf none below threshold   16496002
Combinatorial effect with methyl methanesulphonate (2) Rbf none sp   19543366
Muscle morphogenesis and function (1) Rbf Lethal np   20220848
Heat nociception (1) Rbf none 0.18   21074052
Heart development and function (1) Rbf none 1   20371351
Notch pathway regulation (4) Rbf Notum malformation death 6   19363474
G2-M DNA damage checkpoint regulation (2) Rbf Increased histone H3 phosphorylation with doxorubicin 29.59 with doxorubicin 21205937
G2-M DNA damage checkpoint regulation (2) Rbf Increased histone H3 phosphorylation with etoposide 30.02 with etoposide 21205937
G2-M DNA damage checkpoint regulation (2) Rbf Increased histone H3 phosphorylation after X-ray exposure 38.05 X-ray exposure 21205937
G2-M DNA damage checkpoint regulation (2) Rbf none 12.16 with bleocin 21205937
Hippo pathway regulation Rbf none 1.12   23263283
Glycosylation regulation (1) Rbf none sp   21203496

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