modENCODE |  Help |  blog

Gene : Pten D. melanogaster

DB identifier  ? FBgn0026379 Secondary Identifier  ? CG5671
Name  ? Pten Source  FlyBase
  • synonyms:
  • CG5671,
  • PTEN,
  • FBgn0032201,
  • Drosophila phosphatase and tensin homologue deleted on chromosome 10,
  • DPTEN,
  • phosphatase and tensin homolog,
  • PTEN3,
  • phosphatidylinositol (3,4,5)-trisphosphate phosphatase,
  • FBan0005671,
  • PI 3-phosphatase,
  • FBgn0026379,
  • PtdIns(3,4,5)P3 phosphatase,
  • Phosphatase and tensin homologue

Sequence Feature Displayer

Publication Counts Displayer

Genomics

Gene Ontology Displayer

Homologue Displayer

Mod Mine G Browse Displayer

Overlapping Features Displayer

Regulatory Regions Displayer

45 Alleles

DB identifier Symbol Allele Class Organism
FBal0280530 Pten[Scer\UAS.cUa]   Drosophila melanogaster
FBal0257084 Pten[HMS00044]   Drosophila melanogaster
FBal0276877 Pten[MGH6]   Drosophila melanogaster
FBal0286498 Pten[Scer\UAS.ORF]   Drosophila melanogaster
FBal0286499 Pten[Scer\UAS.ORF.T:Ivir\HA1]   Drosophila melanogaster
FBal0117670 Pten[dj189]   Drosophila melanogaster
FBal0286140 Pten[G137E.3.Scer\UAS]   Drosophila melanogaster
FBal0102917 Pten[+t6.2]   Drosophila melanogaster
FBal0104061 Pten[hs.PG]   Drosophila melanogaster
FBal0104065 Pten[+t6.3]   Drosophila melanogaster
FBal0117672 Pten[+t6]   Drosophila melanogaster
FBal0104063 Pten[3]   Drosophila melanogaster
FBal0191764 Pten[3.cvSa]   Drosophila melanogaster
FBal0182124 Pten[dsRNA.cSa]   Drosophila melanogaster
FBal0117669 Pten[dsRNA.cCa]   Drosophila melanogaster
FBal0190016 Pten[2.cvSa]   Drosophila melanogaster
FBal0144651 Pten[2L100] hypomorphic allele - genetic evidence Drosophila melanogaster
FBal0104064 Pten[1]   Drosophila melanogaster
FBal0120657 Pten[MGH1]   Drosophila melanogaster
FBal0122010 Pten[unspecified]   Drosophila melanogaster
FBal0159967 Pten[dsRNA.cPa]   Drosophila melanogaster
FBal0102915 Pten[c494] loss of function allele Drosophila melanogaster
FBal0141580 Pten[cRa]   Drosophila melanogaster
FBal0141581 Pten[a.cRa]   Drosophila melanogaster
FBal0156018 Pten[mgh3]   Drosophila melanogaster
FBal0120658 Pten[117] loss of function allele Drosophila melanogaster
FBal0150687 Pten[dsRNA.cGa]   Drosophila melanogaster
FBal0197152 Pten[Scer\UAS.cKa]   Drosophila melanogaster
FBal0156022 Pten[1.Act5C.T:Avic\GFP]   Drosophila melanogaster
FBal0156021 Pten[2.Act5C.T:Avic\GFP]   Drosophila melanogaster

39 Clones

Secondary Identifier DB identifier
DPiM_IP16020 FBcl0741646
UUGC0282 FBcl0000017
bs64d06 FBcl0055255
EK287932 FBcl0097916
EK117232 FBcl0097942
EK171137 FBcl0098024
EK179719 FBcl0098030
EK170529 FBcl0098038
EK034305 FBcl0098046
EK251309 FBcl0098054
EK138431 FBcl0098066
EK255133 FBcl0098072
EK265318 FBcl0098076
EK141358 FBcl0098094
RE05970 FBcl0238593
RE66028 FBcl0238611
RE07023 FBcl0238613
RE64115 FBcl0238615
RE20136 FBcl0238630
RE48862 FBcl0238633
RE41458 FBcl0238634
RE50762 FBcl0238641
IP16020 FBcl0303761
103607 FBcl0396493
54792 FBcl0396609
56960 FBcl0396568
180184 FBcl0396586
148894 FBcl0396604
31540 FBcl0396612
104644 FBcl0396661

17 Exons

DB identifier Symbol
FBgn0026379:13 Pten:13
FBgn0026379:11 Pten:11
FBgn0026379:10 Pten:10
FBgn0026379:9 Pten:9
FBgn0026379:8 Pten:8
FBgn0026379:7 Pten:7
FBgn0026379:6 Pten:6
FBgn0026379:5 Pten:5
FBgn0026379:4 Pten:4
FBgn0026379:1 Pten:1
FBgn0026379:3 Pten:3
FBgn0026379:17 Pten:17
FBgn0026379:14 Pten:14
FBgn0026379:12 Pten:12
FBgn0026379:15 Pten:15
FBgn0026379:2 Pten:2
FBgn0026379:16 Pten:16

7 Transcripts

DB identifier Gene
FBtr0089901 Pten
FBtr0089902 Pten
FBtr0089900 Pten
FBtr0089904 Pten
FBtr0089905 Pten
FBtr0300562 Pten
FBtr0301521 Pten

14 UTRs

Class DB identifier
Organism . Name
FivePrimeUTR FBtr0089900-5-prime-utr Drosophila melanogaster
FivePrimeUTR FBtr0089901-5-prime-utr Drosophila melanogaster
FivePrimeUTR FBtr0089904-5-prime-utr Drosophila melanogaster
FivePrimeUTR FBtr0089905-5-prime-utr Drosophila melanogaster
FivePrimeUTR FBtr0089902-5-prime-utr Drosophila melanogaster
FivePrimeUTR FBtr0300562-5-prime-utr Drosophila melanogaster
FivePrimeUTR FBtr0301521-5-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0089900-3-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0089901-3-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0089904-3-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0089905-3-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0089902-3-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0300562-3-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0301521-3-prime-utr Drosophila melanogaster

Interactions

Cytoscape Network Displayer

 

Other

2 Cross References

Identifier
Source . Name

Subject . Primary Identifier
43991 NCBI Entrez Gene identifiers FBgn0026379
68762 BioGRID FBgn0026379

11 Data Sets

Name URL
FlyBase data set for Drosophila melanogaster  
TrEMBL data set http://www.ebi.ac.uk/trembl/
Drosophila 12 Genomes Consortium homology  
GenomeRNAi data set  
TreeFam data set  
Panther data set  
IntAct interactions data set  
BioGRID interaction data set http://www.thebiogrid.org/downloads.php
GO Annotation from FlyBase  
FlyBase fasta data set for Drosophila melanogaster  
Drosophila Cell Line and Developmental Stage Gene and Exon Scores  

55 Expression Scores


Gene . Primary Identifier

Submission . Title

Cell Line . Name

Developmental Stage . Name
Score
FBgn0026379 Drosophila Cell Line and Developmental Stage Gene and Exon Scores CME L1 396.0
FBgn0026379 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Sg4 518.0
FBgn0026379 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD11 498.0
FBgn0026379 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD20-c2 252.0
FBgn0026379 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD20-c5 418.0
FBgn0026379 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Kc167 330.0
FBgn0026379 Drosophila Cell Line and Developmental Stage Gene and Exon Scores GM2 662.0
FBgn0026379 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S2-DRSC 291.0
FBgn0026379 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S2R+ 419.0
FBgn0026379 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S1 696.0
FBgn0026379 Drosophila Cell Line and Developmental Stage Gene and Exon Scores 1182-4H 622.0
FBgn0026379 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD16-c3 470.0
FBgn0026379 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD32 530.0
FBgn0026379 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD17-c3 514.0
FBgn0026379 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD8 480.0
FBgn0026379 Drosophila Cell Line and Developmental Stage Gene and Exon Scores CME W1 Cl.8+ 447.0
FBgn0026379 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD9 639.0
FBgn0026379 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmBG1-c1 453.0
FBgn0026379 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD21 673.0
FBgn0026379 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD4-c1 534.0
FBgn0026379 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmBG3-c2 310.0
FBgn0026379 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S3 491.0
FBgn0026379 Drosophila Cell Line and Developmental Stage Gene and Exon Scores CME W2 509.0
FBgn0026379 Drosophila Cell Line and Developmental Stage Gene and Exon Scores mbn2 591.0
FBgn0026379 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmBG2-c2 842.0
FBgn0026379 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 0-2 h 2480.0
FBgn0026379 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 2-4 h 1566.0
FBgn0026379 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 4-6 h 1055.0
FBgn0026379 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 6-8 h 1184.0
FBgn0026379 Drosophila Cell Line and Developmental Stage Gene and Exon Scores emb 8-10h 971.0

18 Introns

DB identifier
Organism . Name
intron_FBgn0026379:16_FBgn0026379:14 Drosophila melanogaster
intron_FBgn0026379:14_FBgn0026379:12 Drosophila melanogaster
intron_FBgn0026379:12_FBgn0026379:11 Drosophila melanogaster
intron_FBgn0026379:11_FBgn0026379:10 Drosophila melanogaster
intron_FBgn0026379:10_FBgn0026379:9 Drosophila melanogaster
intron_FBgn0026379:9_FBgn0026379:8 Drosophila melanogaster
intron_FBgn0026379:8_FBgn0026379:7 Drosophila melanogaster
intron_FBgn0026379:7_FBgn0026379:6 Drosophila melanogaster
intron_FBgn0026379:6_FBgn0026379:5 Drosophila melanogaster
intron_FBgn0026379:5_FBgn0026379:4 Drosophila melanogaster
intron_FBgn0026379:4_FBgn0026379:1 Drosophila melanogaster
intron_FBgn0026379:13_FBgn0026379:11 Drosophila melanogaster
intron_FBgn0026379:4_FBgn0026379:3 Drosophila melanogaster
intron_FBgn0026379:3_FBgn0026379:1 Drosophila melanogaster
intron_FBgn0026379:17_FBgn0026379:14 Drosophila melanogaster
intron_FBgn0026379:5_FBgn0026379:1 Drosophila melanogaster
intron_FBgn0026379:15_FBgn0026379:12 Drosophila melanogaster
intron_FBgn0026379:4_FBgn0026379:2 Drosophila melanogaster

28 RNAi Results

Screen Gene Phenotype Score Conditions PubMed ID
Cell size regulation Pten none 2.68   19216764
Lipid storage Pten none 1.022021844   19067489
Lipid storage Pten none -0.263647586   19067489
ERK signaling Pten ERK activation reduced strong   17086199
Cell morphology Pten Morphology np   14527345
Cell size and cell-cycle regulation (1) Pten Increased G2 DNA content sp   16496002
Cell size and cell-cycle regulation (1) Pten none sp   16496002
DFoxO signaling Pten Decreased dFoxO reporter activity 0.002   18815370
Combinatorial effect with methyl methanesulphonate (1) Pten none sp   19543366
Combinatorial effect with methyl methanesulphonate (2) Pten none sp   19543366
Mutant human huntingtin aggregation Pten Increased mutant human huntingtin aggregation >= 2   19789644
Muscle morphogenesis and function (1) Pten Semi-lethal np   20220848
Heat nociception (1) Pten none 0.48   21074052
Heart development and function (1) Pten none 1   20371351
Serratia marcescens infection (1) Pten none -0.423529411764705   19520911
Notch pathway regulation (4) Pten Gain of bristles, notum malformation migration, overproliferation sp   19363474
Adiposity regulation (1) Pten none 0.007   20074523
Blood cell homeostasis regulation (1) Pten none np   20540764
Blood cell homeostasis regulation (2) Pten none np   20540764
Vaccinia virus infection Pten none sp   20585561
RTK-Ras-ERK pathway regulation (1) Pten none 0.2 0 minutes EGF stimulation 22028469
RTK-Ras-ERK pathway regulation (1) Pten none 0.2 10 minutes EGF stimulation 22028469
RTK-Ras-ERK pathway regulation (2) Pten none -0.28 30 minutes sSpitz stimulation 22028469
RTK-Ras-ERK pathway regulation (2) Pten none 0.06 10 minutes sSpitz stimulation 22028469
Hippo pathway regulation Pten none -2.25   23263283
Muscle development and maintenance Pten none sp  
Muscle development and maintenance Pten none sp  
Glycosylation regulation (1) Pten none sp   21203496

0 Submissions