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Gene : th D. melanogaster

DB identifier  ? FBgn0260635 Secondary Identifier  ? CG12284
Name  ? thread Source  FlyBase
  • synonyms:
  • TH,
  • rosophila inhibitor of apoptosis protein,
  • l(3)S106503,
  • degradation of inhibitors of apoptosis,
  • DIAPI,
  • FBgn0003691,
  • lethal (3) 72CDe,
  • diap1/thread,
  • DIAP1,
  • FBgn0260635,
  • 1065/03,
  • Drosophila thread/inhibitor of apoptosis protein-1,
  • inhibitor of apoptosis-1,
  • IAP1,
  • Drosophila Inhibitor of Apoptosis 1,
  • Drosophila inhibitor-of-apoptosis protein 1,
  • Drosophila Inhibitor of Apoptosis Protein,
  • l(3)S030605,
  • DIAP,
  • D-IAP1,
  • Thread,
  • S048915,
  • E(rpr)3-1,
  • DIAP-1,
  • DIAP I,
  • diap 1,
  • Drosophila Inhibitor of Apoptosis,
  • IAP,
  • FBgn0011383,
  • Drosophila IAP1,
  • FBgn0046835,
  • l(3)72Dc,
  • Diap2,
  • FBgn0016903,
  • FBan0012284,
  • CG12284,
  • Inhibitor of Apoptosis 1,
  • FBgn0015246,
  • l(3)j5C8,
  • Inhibitors of Apoptosis protein,
  • l(3)72CDe,
  • l(3)S030605b,
  • Drosophila Inhibitor of Apoptosis Protein 1,
  • Drosophila Inhibitor of Apoptosis Protein-1,
  • 0736/01,
  • Inhibitor of Apoptosis Protein 1,
  • Diap-1/Th,
  • FBgn0046836,
  • inhibitor of apoptosis

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181 Alleles

DB identifier Symbol Allele Class Organism
FBal0241427 th[Scer\UAS.cYa]   Drosophila melanogaster
FBal0049851 th[I1]   Drosophila melanogaster
FBal0240188 th[miRNA.GMR]   Drosophila melanogaster
FBal0267300 th[MI05080]   Drosophila melanogaster
FBal0212214 th[miRNA.Scer\UAS]   Drosophila melanogaster
FBal0177495 th[DG29603]   Drosophila melanogaster
FBal0246319 th[Apoliner.Scer\UAS]   Drosophila melanogaster
FBal0246320 th[Apoliner.alphaTub84B]   Drosophila melanogaster
FBal0246321 th[Apomut.alphaTub84B]   Drosophila melanogaster
FBal0177486 th[d11655]   Drosophila melanogaster
FBal0177487 th[d11177]   Drosophila melanogaster
FBal0246254 th[Scer\UAS.T:Hsap\MYC.cBa]   Drosophila melanogaster
FBal0177488 th[d07257]   Drosophila melanogaster
FBal0177490 th[c06574]   Drosophila melanogaster
FBal0257435 th[HMS00752]   Drosophila melanogaster
FBal0215799 th[PBac2148]   Drosophila melanogaster
FBal0177489 th[d00070]   Drosophila melanogaster
FBal0177475 th[f01746]   Drosophila melanogaster
FBal0177476 th[e03559]   Drosophila melanogaster
FBal0177477 th[e02749]   Drosophila melanogaster
FBal0276787 th[Scer\UAS.cUa]   Drosophila melanogaster
FBal0177491 th[c06094]   Drosophila melanogaster
FBal0129005 th[EP3451]   Drosophila melanogaster
FBal0158579 th[EY07925]   Drosophila melanogaster
FBal0010971 th[j5C8]   Drosophila melanogaster
FBal0129006 th[EP3279]   Drosophila melanogaster
FBal0154457 th[EP3308]   Drosophila melanogaster
FBal0129003 th[EP3723]   Drosophila melanogaster
FBal0060876 th[228]   Drosophila melanogaster
FBal0060875 th[355]   Drosophila melanogaster

101 Clones

Secondary Identifier DB identifier
ESG0118a.B21_E10 FBcl0002979
ESG0115c.B21_A02 FBcl0007223
ESG014c.E21_C12 FBcl0008561
AT14109 FBcl0011407
AT04572 FBcl0011419
AT22874 FBcl0011451
ESG013c.E21_F01 FBcl0011725
ESG011a.E21_H04 FBcl0013393
bs80h08 FBcl0048625
EK201031 FBcl0049446
EK160515 FBcl0049702
EK288357 FBcl0049714
EK173234 FBcl0049726
EK054344 FBcl0049728
EK059257 FBcl0049732
EK110522 FBcl0049760
EK155559 FBcl0049766
EK203836 FBcl0049768
EK249923 FBcl0049780
EK139264 FBcl0049786
EK059241 FBcl0049800
EK179835 FBcl0050496
EK236046 FBcl0050588
EK144617 FBcl0050638
EK044835 FBcl0050644
EK146539 FBcl0050674
EK235846 FBcl0050688
EK185051 FBcl0050696
EK119935 FBcl0050706
EP09926 FBcl0076809

7 Exons

DB identifier Symbol
FBgn0260635:6 th:6
FBgn0260635:1 th:1
FBgn0260635:5 th:5
FBgn0260635:3 th:3
FBgn0260635:2 th:2
FBgn0260635:4 th:4
FBgn0260635:7 th:7

6 Transcripts

DB identifier Gene
FBtr0075499 th
FBtr0333619 th
FBtr0333618 th
FBtr0333617 th
FBtr0075501 th
FBtr0075500 th

12 UTRs

Class DB identifier
Organism . Name
FivePrimeUTR FBtr0075499-5-prime-utr Drosophila melanogaster
FivePrimeUTR FBtr0075500-5-prime-utr Drosophila melanogaster
FivePrimeUTR FBtr0075501-5-prime-utr Drosophila melanogaster
FivePrimeUTR FBtr0333617-5-prime-utr Drosophila melanogaster
FivePrimeUTR FBtr0333618-5-prime-utr Drosophila melanogaster
FivePrimeUTR FBtr0333619-5-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0075499-3-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0075500-3-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0075501-3-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0333617-3-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0333618-3-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0333619-3-prime-utr Drosophila melanogaster


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0 Pathways

2 Cross References

Source . Name

Subject . Primary Identifier
39753 NCBI Entrez Gene identifiers FBgn0260635
65064 BioGRID FBgn0260635

10 Data Sets

Name URL
FlyBase data set for Drosophila melanogaster  
Swiss-Prot data set
Drosophila 12 Genomes Consortium homology  
GenomeRNAi data set  
TreeFam data set  
Panther data set  
IntAct interactions data set  
BioGRID interaction data set
GO Annotation from FlyBase  
FlyBase fasta data set for Drosophila melanogaster  

0 Expression Scores

7 Introns

DB identifier
Organism . Name
intron_FBgn0260635:7_FBgn0260635:1 Drosophila melanogaster
intron_FBgn0260635:5_FBgn0260635:1 Drosophila melanogaster
intron_FBgn0260635:6_FBgn0260635:1 Drosophila melanogaster
intron_FBgn0260635:3_FBgn0260635:1 Drosophila melanogaster
intron_FBgn0260635:2_FBgn0260635:1 Drosophila melanogaster
intron_FBgn0260635:5_FBgn0260635:4 Drosophila melanogaster
intron_FBgn0260635:4_FBgn0260635:1 Drosophila melanogaster

36 RNAi Results

Screen Gene Phenotype Score Conditions PubMed ID
Lipid storage th Decreased lipid droplet area -2.891251609   19067489
Lipid storage th Decreased lipid droplet area -4.440245615   19067489
Lipid storage th Decreased lipid droplet area 0.086782514   19067489
Neural outgrowth th Cell loss np   18604272
Chlamydia caviae infection th Decreased Chlamydia caviae infection np   17967059
ERK signaling th ERK activation reduced strong   17086199
Cell morphology th Morphology np   14527345
Intracellular Listeria monocytogenes infection th Decreased GFP protein expression strong   16020693
Hedgehog signaling th Decreased Hedgehog reporter activity -2.29   16311596
Mycobacterial infection (1) - M. fortuitum infection th Decreased M. fortuitum intracellular infection 12 measurement after 3 days 16020694
Mycobacterial infection (2) - E. coli phagocytosis th Decreased E. coli phagocytosis np   16020694
Constitutive protein secretion and Golgi organization (1) th Decreased horseradish peroxidase protein expression sp   16452979
Cell size and cell-cycle regulation (1) th Decreased G2 DNA content, decreased G1 cell size, decreased viability, increased cytokinesis sp   16496002
Cell size and cell-cycle regulation (2) th none 1.333   16496002
Cell size and cell-cycle regulation (3) th none 430   16496002
Embryonic nervous system development th Disorganization and loss of neurons of ventral nerve cord and peripheral nervous system np   15534205
Mitochondrial biogenesis and function th Increased mitochondrial citrate synthase activity, decreased viability 1.181   18042644
Mutant human huntingtin aggregation th Decreased mutant human huntingtin aggregation <= -2   19789644
Muscle morphogenesis and function (1) th Lethal np   20220848
Muscle morphogenesis and function (3) th none np   20220848
Notch pathway regulation (4) th Completely lethal (before pupal) sp   19363474
Hh pathway regulation th none 0.3268897706833   17903264
Hh pathway regulation th Upregulation of Hh pathway 0.739622606753532   17903264
Notch pathway regulation (3) th none np   20493818
Actin organization and cell morphology (1) th none np   19265526
Actin organization and cell morphology (2) th none np   19265526
Actin organization and cell morphology (3) th none np   19265526
Actin organization and cell morphology (4) th none np   19265526
Actin organization and cell morphology (5) th none np   19265526
Actin organization and cell morphology (6) th none np   19265526

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