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Gene : pav D. melanogaster

DB identifier  ? FBgn0011692 Secondary Identifier  ? CG1258
Name  ? pavarotti Source  FlyBase
  • synonyms:
  • Mitotic kinesin-like protein 1,
  • anon-fast-evolving-2A12,
  • PAV-MKLP,
  • KIF 23,
  • KIF23,
  • DmPAV,
  • group D,
  • Mklp1,
  • 2A12MEL,
  • PavKLP,
  • PAV-KLP,
  • Kinesin-6,
  • Pav KLP,
  • 2A12,
  • 0973/08,
  • DmMKLP1,
  • 0934/13,
  • Pavarotti KLP,
  • anon2A12,
  • Pavarroti,
  • anon-EST:fe2A12,
  • Pavarotti-KLP,
  • DmKLP1/pav,
  • PAV/KLP,
  • PAV,
  • Pavarotti,
  • CG1258,
  • FBgn0022345,
  • FBan0001258,
  • FBgn0011692

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48 Alleles

DB identifier Symbol Allele Class Organism
FBal0220926 pav[G7076]   Drosophila melanogaster
FBal0281416 pav[HMJ02232]   Drosophila melanogaster
FBal0212229 pav[MtnA.NES.T:Avic\GFP]   Drosophila melanogaster
FBal0212230 pav[T7A.MtnA.T:Avic\GFP]   Drosophila melanogaster
FBal0212231 pav[T15A.MtnA.T:Avic\GFP]   Drosophila melanogaster
FBal0212232 pav[T7A.T15A.MtnA.T:Avic\GFP]   Drosophila melanogaster
FBal0212233 pav[T458A.MtnA.T:Avic\GFP]   Drosophila melanogaster
FBal0212234 pav[T467A.MtnA.T:Avic\GFP]   Drosophila melanogaster
FBal0212235 pav[T458A.T467A.MtnA.T:Avic\GFP]   Drosophila melanogaster
FBal0212236 pav[S836A.MtnA.T:Avic\GFP]   Drosophila melanogaster
FBal0212237 pav[S840A.MtnA.T:Avic\GFP]   Drosophila melanogaster
FBal0212238 pav[S836A.S840A.MtnA.T:Avic\GFP]   Drosophila melanogaster
FBal0212239 pav[T7A.T15A.T458A.T467A.MtnA.T:Avic\GFP]   Drosophila melanogaster
FBal0258799 pav[KK100707]   Drosophila melanogaster
FBal0082375 pav[S097308]   Drosophila melanogaster
FBal0082376 pav[S093413]   Drosophila melanogaster
FBal0122937 pav[Scim]   Drosophila melanogaster
FBal0090201 pav[+t10.5]   Drosophila melanogaster
FBal0090200 pav[RC2]   Drosophila melanogaster
FBal0286730 pav[Scer\UAS.ORF]   Drosophila melanogaster
FBal0286731 pav[Scer\UAS.ORF.T:Ivir\HA1]   Drosophila melanogaster
FBal0178482 pav[dsRNA.cGa]   Drosophila melanogaster
FBal0096728 pav[unspecified]   Drosophila melanogaster
FBal0050243 pav[D295] loss of function allele Drosophila melanogaster
FBal0050246 pav[M547] loss of function allele Drosophila melanogaster
FBal0063824 pav[P59]   Drosophila melanogaster
FBal0146926 pav[dsRNA.1151-2081]   Drosophila melanogaster
FBal0178490 pav[2046]   Drosophila melanogaster
FBal0050242 pav[B200] loss of function allele Drosophila melanogaster
FBal0050244 pav[L157] loss of function allele Drosophila melanogaster

75 Clones

Secondary Identifier DB identifier
AA433236 FBcl0000401
EK264456 FBcl0081756
EK039422 FBcl0083126
EK167053 FBcl0083142
EK116506 FBcl0083190
EK040214 FBcl0083204
EK026824 FBcl0083220
EK263118 FBcl0083232
EK224161 FBcl0083248
EK292940 FBcl0083260
EK259729 FBcl0083276
EK192458 FBcl0083296
EK123354 FBcl0083312
EK255025 FBcl0083324
EN11321 FBcl0091473
GH14862 FBcl0106699
GM31142 FBcl0144191
LD06979 FBcl0152226
LD05511 FBcl0152293
LD05510 FBcl0152298
LD08574 FBcl0152300
LD18976 FBcl0152309
LD13095 FBcl0152312
LD15576 FBcl0152313
LD31080 FBcl0164735
LD38918 FBcl0164842
LD42622 FBcl0164847
LD33456 FBcl0164849
LD45619 FBcl0164850
LD41854 FBcl0164853

6 Exons

DB identifier Symbol
FBgn0011692:1 pav:1
FBgn0011692:2 pav:2
FBgn0011692:3 pav:3
FBgn0011692:4 pav:4
FBgn0011692:5 pav:5
FBgn0011692:6 pav:6

1 Transcripts

DB identifier Gene
FBtr0073227 pav

2 UTRs

Class DB identifier
Organism . Name
FivePrimeUTR FBtr0073227-5-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0073227-3-prime-utr Drosophila melanogaster

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2 Cross References

Identifier
Source . Name

Subject . Primary Identifier
38515 NCBI Entrez Gene identifiers FBgn0011692
63993 BioGRID FBgn0011692

11 Data Sets

Name URL
FlyBase data set for Drosophila melanogaster  
TrEMBL data set http://www.ebi.ac.uk/trembl/
Drosophila 12 Genomes Consortium homology  
GenomeRNAi data set  
TreeFam data set  
Panther data set  
IntAct interactions data set  
BioGRID interaction data set http://www.thebiogrid.org/downloads.php
GO Annotation from FlyBase  
FlyBase fasta data set for Drosophila melanogaster  
Drosophila Cell Line and Developmental Stage Gene and Exon Scores  

55 Expression Scores


Gene . Primary Identifier

Submission . Title

Cell Line . Name

Developmental Stage . Name
Score
FBgn0011692 Drosophila Cell Line and Developmental Stage Gene and Exon Scores CME L1 1170.0
FBgn0011692 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Sg4 1227.0
FBgn0011692 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD11 1395.0
FBgn0011692 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD20-c2 1415.0
FBgn0011692 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD20-c5 1732.0
FBgn0011692 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Kc167 577.0
FBgn0011692 Drosophila Cell Line and Developmental Stage Gene and Exon Scores GM2 449.0
FBgn0011692 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S2-DRSC 1350.0
FBgn0011692 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S2R+ 854.0
FBgn0011692 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S1 1478.0
FBgn0011692 Drosophila Cell Line and Developmental Stage Gene and Exon Scores 1182-4H 1737.0
FBgn0011692 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD16-c3 1402.0
FBgn0011692 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD32 1126.0
FBgn0011692 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD17-c3 1126.0
FBgn0011692 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD8 1548.0
FBgn0011692 Drosophila Cell Line and Developmental Stage Gene and Exon Scores CME W1 Cl.8+ 1078.0
FBgn0011692 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD9 1142.0
FBgn0011692 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmBG1-c1 1170.0
FBgn0011692 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD21 1186.0
FBgn0011692 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD4-c1 1213.0
FBgn0011692 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmBG3-c2 1103.0
FBgn0011692 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S3 1408.0
FBgn0011692 Drosophila Cell Line and Developmental Stage Gene and Exon Scores CME W2 1546.0
FBgn0011692 Drosophila Cell Line and Developmental Stage Gene and Exon Scores mbn2 1015.0
FBgn0011692 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmBG2-c2 937.0
FBgn0011692 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 0-2 h 3458.0
FBgn0011692 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 2-4 h 2234.0
FBgn0011692 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 4-6 h 3174.0
FBgn0011692 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 6-8 h 2064.0
FBgn0011692 Drosophila Cell Line and Developmental Stage Gene and Exon Scores emb 8-10h 1484.0

5 Introns

DB identifier
Organism . Name
intron_FBgn0011692:1_FBgn0011692:2 Drosophila melanogaster
intron_FBgn0011692:2_FBgn0011692:3 Drosophila melanogaster
intron_FBgn0011692:3_FBgn0011692:4 Drosophila melanogaster
intron_FBgn0011692:4_FBgn0011692:5 Drosophila melanogaster
intron_FBgn0011692:5_FBgn0011692:6 Drosophila melanogaster

27 RNAi Results

Screen Gene Phenotype Score Conditions PubMed ID
Lipid storage pav none 1.17016525   19067489
Lipid storage pav none -0.838311366   19067489
Chlamydia caviae infection pav Decreased Chlamydia caviae infection np   17967059
Ca2+ signaling pav Decreased NFAT translocation np   17293345
ERK signaling pav ERK activation reduced weak   17086199
Mitosis pav Cytokinesis defect np   12975346
Cell morphology pav Morphology np   14527345
Cytokinesis pav Multi-nucleate cells np   15380073
Cytokinesis regulation pav Binucleate cells strong   15547975
Intracellular Listeria monocytogenes infection pav Increased GFP protein expression moderate   16020693
Cell size and cell-cycle regulation (1) pav Increased cytokinesis sp   16496002
Mitosis pav Multipolar spindle np   17412918
Lipid storage pav Smaller sized lipid droplets, more dispersed moderate   18408709
Muscle morphogenesis and function (1) pav Locomotion defect np   20220848
Heat nociception (1) pav Developmentally lethal 0   21074052
Heat nociception (1) pav Developmentally lethal 0   21074052
Heart development and function (1) pav none 1   20371351
Notch pathway regulation (4) pav Notum malformation death 7   19363474
Self-renewal and differentiation in neural stem cells pav GFP aggregates number, GFP aggregates size, neuroblast abnormally large cell size, neuroblast larger cell size, neuroblast cell shape, ganglion mother cell shorter lineages, extremely increased neuroblast cell size without neuroblast loss, neuroblast unde sp   21549331
RTK-Ras-ERK pathway regulation (1) pav none 0.77 0 minutes EGF stimulation 22028469
RTK-Ras-ERK pathway regulation (1) pav none -0.75 10 minutes EGF stimulation 22028469
RTK-Ras-ERK pathway regulation (2) pav none -0.36 10 minutes sSpitz stimulation 22028469
RTK-Ras-ERK pathway regulation (2) pav none 0.99 30 minutes sSpitz stimulation 22028469
Wnt proteins secretion pav none -0.7   22094269
Hippo pathway regulation pav none 0.1   23263283
Muscle development and maintenance pav none sp  
Glycosylation regulation (1) pav none sp   21203496

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