modENCODE |  Help |  blog

Protein : FBpp0074487 D. melanogaster

Primary Accession  ? Q0KHQ6 Organism . Name  Drosophila melanogaster
MD5 Checksum  cee8104552d505971c263885e23dc36a UniProt Accession  Q0KHQ6
UniProt Name  Q0KHQ6_DROME GenBank Identifier  AAN09491
Is UniProt Canonical  true Is Fragment  false
Length  536 Molecular Weight  60804
Name  6-phosphofructo-2-kinase, isoform M Secondary Identifier  FBpp0074487

Publication Counts Displayer

Uni Prot Comments Displayer

Protein Sequence Displayer


1 Genes

DB identifier Secondary Identifier Symbol Name Source Organism
FBgn0027621 CG3400 Pfrx 6-phosphofructo-2-kinase FlyBase D. melanogaster


Protein --> Gene + chromosomal location and length of the gene.


Cytoscape Network Displayer



0 Components

10 Cross References

Source . Name

Subject . Primary Identifier
NP_001245752.1 RefSeq FBpp0074487
NP_728253.1 RefSeq FBpp0074487
NP_728252.1 RefSeq FBpp0074487
Dm.7752 UniGene FBpp0074487
NP_728249.1 RefSeq FBpp0074487
NP_728254.1 RefSeq FBpp0074487
NP_001245750.1 RefSeq FBpp0074487
NP_728250.1 RefSeq FBpp0074487
NP_728251.1 RefSeq FBpp0074487
NP_001245751.1 RefSeq FBpp0074487

3 Data Sets

Name URL
FlyBase data set for Drosophila melanogaster  
TrEMBL data set
Reactome data set  

2 Ec Numbers

Identifier Description  

10 Locations

Located On . Primary Identifier
Start End Strand
X 19400950 19402557 1
X 19400950 19402557 1
X 19400950 19402557 1
X 19400950 19402557 1
X 19400950 19402557 1
X 19400950 19402557 1
X 19400950 19402557 1
X 19400950 19402557 1
X 19400950 19402557 1
X 19400950 19402557 1

56 Pathways

Identifier Name
89538 Integration of energy metabolism
105036 PP2A-mediated dephosphorylation of key metabolic factors
106873 Insulin effects increased synthesis of Xylulose-5-Phosphate
133721 PKA-mediated phosphorylation of key metabolic factors
80338 PKA activation in glucagon signalling
97918 Glucagon signaling in metabolic regulation
106046 Carbohydrate metabolism
112201 Metabolism
85514 GPCR downstream signaling
81642 G alpha (s) signalling events
96239 DARPP-32 events
32504 Opioid Signalling
84461 Ca-dependent events
99045 G-protein mediated events
30626 PLC beta mediated events
81368 Signaling by GPCR
154100 Inositol phosphate metabolism
34103 Fructose catabolism
77782 Gluconeogenesis
104018 Glycolysis
30754 Glucose metabolism
90926 Pentose phosphate pathway (hexose monophosphate shunt)
105951 Immune System
88681 Innate Immune System
113552 Developmental Biology
93479 Regulation of beta-cell development
97083 Regulation of gene expression in beta cells
149356 DAP12 interactions
150048 DAP12 signaling
118381 Disease

7 Protein Domains

DB identifier Name Short Name Type
IPR029033 Histidine phosphatase superfamily His_PPase_superfam Family
IPR027417 P-loop containing nucleoside triphosphate hydrolase P-loop_NTPase Domain
IPR013078 Histidine phosphatase superfamily, clade-1 His_Pase_superF_clade-1 Family
IPR003094 Fructose-2,6-bisphosphatase 6Pfruct_kin Family
IPR013079 6-phosphofructo-2-kinase 6Phosfructo_kin Domain
IPR016260 Bifunctional 6-phosphofructo-2-kinase/fructose-2, 6-bisphosphate 2-phosphatase Bifunct_6PFK/fruc_bisP_Ptase Family
IPR001345 Phosphoglycerate/bisphosphoglycerate mutase, active site PG/BPGM_mutase_AS Active_site

10 Transcripts

DB identifier Gene
FBtr0074715 Pfrx
FBtr0074713 Pfrx
FBtr0074718 Pfrx
FBtr0339439 Pfrx
FBtr0074719 Pfrx
FBtr0307193 Pfrx
FBtr0307192 Pfrx
FBtr0074714 Pfrx
FBtr0074720 Pfrx
FBtr0307194 Pfrx