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Gene : sktl D. melanogaster

DB identifier  ? FBgn0016984 Secondary Identifier  ? CG9985
Name  ? skittles Source  FlyBase
  • synonyms:
  • FBgn0016984,
  • ski,
  • fata morgana,
  • FBan0009985,
  • PIP5-kinase,
  • fam,
  • FBgn0015387,
  • 25/17,
  • PIP5K,
  • l(2)05475,
  • type I phosphatidylinositol 4-phosphate 5-kinase,
  • FBgn0010601,
  • Skittles,
  • Sktl,
  • CG9985,
  • l(2)k12405,
  • PIP5K 57B6

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35 Alleles

DB identifier Symbol Allele Class Organism
FBal0230436 sktl[2.3] loss of function allele Drosophila melanogaster
FBal0230437 sktl[M5]   Drosophila melanogaster
FBal0230438 sktl[Scer\UAS.P\T.cGa]   Drosophila melanogaster
FBal0230440 sktl[Scer\UAS.P\T.T:Disc\RFP]   Drosophila melanogaster
FBal0230439 sktl[Scer\UAS.P\T.T:Avic\GFP]   Drosophila melanogaster
FBal0230441 sktl[tub.PG]   Drosophila melanogaster
FBal0177898 sktl[DG24311]   Drosophila melanogaster
FBal0245268 sktl[betaTub85D.T:Avic\GFP-YFP]   Drosophila melanogaster
FBal0241095 sktl[Scer\UAS.cRa]   Drosophila melanogaster
FBal0241096 sktl[KD.Scer\UAS]   Drosophila melanogaster
FBal0094335 sktl[k02608]   Drosophila melanogaster
FBal0094333 sktl[k07701]   Drosophila melanogaster
FBal0094331 sktl[k12405]   Drosophila melanogaster
FBal0094330 sktl[k13706]   Drosophila melanogaster
FBal0094332 sktl[k10907]   Drosophila melanogaster
FBal0094336 sktl[k02517]   Drosophila melanogaster
FBal0094338 sktl[05475]   Drosophila melanogaster
FBal0094339 sktl[03679]   Drosophila melanogaster
FBal0094334 sktl[k07505]   Drosophila melanogaster
FBal0094340 sktl[Delta9]   Drosophila melanogaster
FBal0094341 sktl[Delta5] loss of function allele Drosophila melanogaster
FBal0094346 sktl[Delta13]   Drosophila melanogaster
FBal0158668 sktl[unspecified]   Drosophila melanogaster
FBal0094344 sktl[Delta20] loss of function allele Drosophila melanogaster
FBal0094343 sktl[Delta24]   Drosophila melanogaster
FBal0094342 sktl[Delta31]   Drosophila melanogaster
FBal0094345 sktl[Delta15] loss of function allele Drosophila melanogaster
FBal0262559 sktl[GL00072]   Drosophila melanogaster
FBal0197220 sktl[Delta1-1] hypomorphic allele - genetic evidence Drosophila melanogaster
FBal0094337 sktl[Scer\UAS.cHa]   Drosophila melanogaster

34 Clones

Secondary Identifier DB identifier
DPiM_LP03320 FBcl0741338
EK136224 FBcl0048028
EK258210 FBcl0048030
CK01121 FBcl0060303
LD19550 FBcl0155265
LP15593 FBcl0183712
LP03320 FBcl0183717
LP06742 FBcl0183726
RE56619 FBcl0208207
RE54387 FBcl0208754
RE12328 FBcl0208859
RE58714 FBcl0208907
RE56295 FBcl0208927
RE42868 FBcl0208940
RE50517 FBcl0208942
RE36729 FBcl0208944
RE30268 FBcl0208982
RH24103 FBcl0252311
SD26614 FBcl0289006
SD20447 FBcl0289008
SD27937 FBcl0289011
SD21217 FBcl0289012
SD14322 FBcl0289013
SD04331 FBcl0289029
FGH129F01 FBcl0388709
RP01733 FBcl0643639
RP001045011 FBcl0643640
RP001044884 FBcl0643644
RP001034720 FBcl0643648
RP001040813 FBcl0643650

4 Exons

DB identifier Symbol
FBgn0016984:3 sktl:3
FBgn0016984:2 sktl:2
FBgn0016984:1 sktl:1
FBgn0016984:4 sktl:4

3 Transcripts

DB identifier Gene
FBtr0071563 sktl
FBtr0342801 sktl
FBtr0344196 sktl

6 UTRs

Class DB identifier
Organism . Name
FivePrimeUTR FBtr0071563-5-prime-utr Drosophila melanogaster
FivePrimeUTR FBtr0342801-5-prime-utr Drosophila melanogaster
FivePrimeUTR FBtr0344196-5-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0071563-3-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0342801-3-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0344196-3-prime-utr Drosophila melanogaster

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2 Cross References

Identifier
Source . Name

Subject . Primary Identifier
37356 NCBI Entrez Gene identifiers FBgn0016984
63002 BioGRID FBgn0016984

11 Data Sets

Name URL
FlyBase data set for Drosophila melanogaster  
TrEMBL data set http://www.ebi.ac.uk/trembl/
Drosophila 12 Genomes Consortium homology  
GenomeRNAi data set  
TreeFam data set  
Panther data set  
IntAct interactions data set  
BioGRID interaction data set http://www.thebiogrid.org/downloads.php
GO Annotation from FlyBase  
FlyBase fasta data set for Drosophila melanogaster  
Drosophila Cell Line and Developmental Stage Gene and Exon Scores  

55 Expression Scores


Gene . Primary Identifier

Submission . Title

Cell Line . Name

Developmental Stage . Name
Score
FBgn0016984 Drosophila Cell Line and Developmental Stage Gene and Exon Scores CME L1 1001.0
FBgn0016984 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Sg4 1088.0
FBgn0016984 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD11 495.0
FBgn0016984 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD20-c2 1470.0
FBgn0016984 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD20-c5 1277.0
FBgn0016984 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Kc167 476.0
FBgn0016984 Drosophila Cell Line and Developmental Stage Gene and Exon Scores GM2 968.0
FBgn0016984 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S2-DRSC 1350.0
FBgn0016984 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S2R+ 675.0
FBgn0016984 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S1 858.0
FBgn0016984 Drosophila Cell Line and Developmental Stage Gene and Exon Scores 1182-4H 518.0
FBgn0016984 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD16-c3 743.0
FBgn0016984 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD32 1063.0
FBgn0016984 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD17-c3 760.0
FBgn0016984 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD8 925.0
FBgn0016984 Drosophila Cell Line and Developmental Stage Gene and Exon Scores CME W1 Cl.8+ 991.0
FBgn0016984 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD9 1018.0
FBgn0016984 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmBG1-c1 632.0
FBgn0016984 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD21 854.0
FBgn0016984 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD4-c1 1183.0
FBgn0016984 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmBG3-c2 1240.0
FBgn0016984 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S3 1354.0
FBgn0016984 Drosophila Cell Line and Developmental Stage Gene and Exon Scores CME W2 863.0
FBgn0016984 Drosophila Cell Line and Developmental Stage Gene and Exon Scores mbn2 906.0
FBgn0016984 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmBG2-c2 583.0
FBgn0016984 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 0-2 h 1903.0
FBgn0016984 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 2-4 h 592.0
FBgn0016984 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 4-6 h 807.0
FBgn0016984 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 6-8 h 744.0
FBgn0016984 Drosophila Cell Line and Developmental Stage Gene and Exon Scores emb 8-10h 787.0

3 Introns

DB identifier
Organism . Name
intron_FBgn0016984:3_FBgn0016984:1 Drosophila melanogaster
intron_FBgn0016984:3_FBgn0016984:2 Drosophila melanogaster
intron_FBgn0016984:4_FBgn0016984:2 Drosophila melanogaster

25 RNAi Results

Screen Gene Phenotype Score Conditions PubMed ID
Lipid storage sktl none -1.058239007   19067489
Lipid storage sktl none -1.428390252   19067489
Neural outgrowth sktl Cell cluster defect np   18604272
Mitochondrial morphology sktl Perinuclear Mitochondria np   18353969
Cell size and cell-cycle regulation (1) sktl none sp   16496002
DFoxO signaling sktl Decreased dFoxO reporter activity 0.2   18815370
Mutant human huntingtin aggregation sktl Increased mutant human huntingtin aggregation 1.5 - 2   19789644
Muscle morphogenesis and function (1) sktl Lethal np   20220848
Muscle morphogenesis and function (1) sktl none np   20220848
Muscle morphogenesis and function (2) sktl Wing posture / locomotion / ability to fly defect or lethal / semi-lethal np   20220848
Heat nociception (1) sktl none 1.11   21074052
Heart development and function (1) sktl none 1   20371351
Serratia marcescens infection (1) sktl none -0.972727272727272   19520911
Notch pathway regulation (4) sktl Completely lethal (pupal) sp   19363474
Notch pathway regulation (4) sktl Completely lethal (pupal) sp   19363474
Akt-TOR pathway negative feedback regulation sktl none -2.3 10 min insulin stimulation 20585550
Adiposity regulation (1) sktl none -0.093   20074523
Actin organization and cell morphology (1) sktl none np   19265526
Actin organization and cell morphology (2) sktl none np   19265526
Actin organization and cell morphology (3) sktl none np   19265526
Actin organization and cell morphology (4) sktl none np   19265526
Actin organization and cell morphology (5) sktl none np   19265526
Actin organization and cell morphology (6) sktl none np   19265526
Vaccinia virus infection sktl none sp   20585561
Hippo pathway regulation sktl none -0.79   23263283

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