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Gene : N D. melanogaster

DB identifier  ? FBgn0004647 Secondary Identifier  ? CG3936
Name  ? Notch Source  FlyBase
  • synonyms:
  • Chp,
  • swb,
  • 16-178,
  • shd,
  • clone 1.12,
  • Co,
  • facet,
  • FBgn0017616,
  • notchoid,
  • n[fah],
  • CT13012,
  • Ax,
  • nd,
  • FBgn0024967,
  • Abruptex,
  • NICD,
  • l(1)3Cb,
  • strawberry,
  • FBan0003936,
  • spl,
  • Confluens,
  • FBgn0026804,
  • NECD,
  • CG3936,
  • FBgn0002916,
  • FBgn0000311,
  • NOTCH,
  • EG:140G11.1,
  • 16-55,
  • split,
  • EG:163A10.2,
  • fa,
  • anon-EST:Liang-1.12,
  • l(1)N,
  • FBgn0004647,
  • l(1)Ax,
  • Chopped,
  • N,
  • dNotch,
  • 1.1

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713 Alleles

DB identifier Symbol Allele Class Organism
FBal0257052 N[HMS00001]   Drosophila melanogaster
FBal0267499 N[FU42]   Drosophila melanogaster
FBal0257057 N[HMS00009]   Drosophila melanogaster
FBal0261034 N[AX1682]   Drosophila melanogaster
FBal0268102 N[dsRNA.Scer\UAS.cHa]   Drosophila melanogaster
FBal0243919 N[Scer\UAS.T:SV5\V5,T:Zzzz\His6]   Drosophila melanogaster
FBal0243920 N[NEXT.Scer\UAS.T:Ivir\HA1,T:SV5\V5,T:Zzzz\His6]   Drosophila melanogaster
FBal0197789 N[865.Scer\UAS]   Drosophila melanogaster
FBal0197790 N[EGF12f.Scer\UAS]   Drosophila melanogaster
FBal0197791 N[EGF24f.Scer\UAS]   Drosophila melanogaster
FBal0197792 N[EGF26f.Scer\UAS]   Drosophila melanogaster
FBal0280339 N[jigsaw]   Drosophila melanogaster
FBal0197793 N[EGF31f.Scer\UAS]   Drosophila melanogaster
FBal0197794 N[EGF12f.MtnA]   Drosophila melanogaster
FBal0216236 N[no1]   Drosophila melanogaster
FBal0197795 N[EGF.10-12.MtnA.Bip.T:SV5\V5,T:Zzzz\His6]   Drosophila melanogaster
FBal0197796 N[EGF.10-12f.MtnA.Bip.T:SV5\V5,T:Zzzz\His6]   Drosophila melanogaster
FBal0197797 N[EGF12f.MtnA.T:Hsap\ALPP]   Drosophila melanogaster
FBal0261122 N[dsRNA.Scer\UAS.cUa]   Drosophila melanogaster
FBal0270136 N[VDRC.cUa]   Drosophila melanogaster
FBal0282136 N[nd-1-dse] temperature conditional hypermorphic allele - genetic evidence, temperature conditional hypermorphic allele - molecular evidence, hypomorphic allele - genetic evidence Drosophila melanogaster
FBal0282542 N[5XUAS.JF01356]   Drosophila melanogaster
FBal0240321 N[JF01637]   Drosophila melanogaster
FBal0283126 N[Scer\UAS.T:Avic\GFP]   Drosophila melanogaster
FBal0283127 N[Scer\UAS.T:Disc\RFP-mCherry]   Drosophila melanogaster
FBal0245259 N[DeltaN.S2.Scer\UAS.T:Ecol\lexA,T:Hsim\VP16]   Drosophila melanogaster
FBal0284399 N[hs.cUa]   Drosophila melanogaster
FBal0284400 N[DeltaECD.hs.cUa]   Drosophila melanogaster
FBal0245381 N[JF01053]   Drosophila melanogaster
FBal0245380 N[JF01043]   Drosophila melanogaster

91 Clones

Secondary Identifier DB identifier
ESG0117d.B21_B04 FBcl0003193
CK01709 FBcl0058917
EK304103 FBcl0060056
EK094115 FBcl0060076
EK022506 FBcl0060106
EK250543 FBcl0060116
EK139863 FBcl0060130
EK179431 FBcl0060144
EK095533 FBcl0060160
EK094124 FBcl0060170
EK111517 FBcl0060184
EK184715 FBcl0060208
EK173929 FBcl0060218
EK239818 FBcl0060230
EK030003 FBcl0060240
EK142918 FBcl0060254
EK257406 FBcl0060274
EK162823 FBcl0060298
EK293156 FBcl0060330
EN16316 FBcl0090709
LD34134 FBcl0173433
LD34342 FBcl0173435
LP10228 FBcl0187351
RE01368 FBcl0222511
RH53237 FBcl0262534
RH67406 FBcl0262537
RH27767 FBcl0262554
RH27791 FBcl0262556
RH31644 FBcl0262558
RH57292 FBcl0262561

10 Exons

DB identifier Symbol
FBgn0004647:1 N:1
FBgn0004647:2 N:2
FBgn0004647:3 N:3
FBgn0004647:4 N:4
FBgn0004647:5 N:5
FBgn0004647:6 N:6
FBgn0004647:7 N:7
FBgn0004647:8 N:8
FBgn0004647:10 N:10
FBgn0004647:9 N:9

2 Transcripts

DB identifier Gene
FBtr0070507 N
FBtr0304659 N

4 UTRs

Class DB identifier
Organism . Name
FivePrimeUTR FBtr0070507-5-prime-utr Drosophila melanogaster
FivePrimeUTR FBtr0304659-5-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0070507-3-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0304659-3-prime-utr Drosophila melanogaster

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2 Cross References

Identifier
Source . Name

Subject . Primary Identifier
31293 NCBI Entrez Gene identifiers FBgn0004647
57823 BioGRID FBgn0004647

11 Data Sets

Name URL
FlyBase data set for Drosophila melanogaster  
Swiss-Prot data set http://ca.expasy.org/sprot
Drosophila 12 Genomes Consortium homology  
GenomeRNAi data set  
TreeFam data set  
Panther data set  
IntAct interactions data set  
BioGRID interaction data set http://www.thebiogrid.org/downloads.php
GO Annotation from FlyBase  
FlyBase fasta data set for Drosophila melanogaster  
Drosophila Cell Line and Developmental Stage Gene and Exon Scores  

55 Expression Scores


Gene . Primary Identifier

Submission . Title

Cell Line . Name

Developmental Stage . Name
Score
FBgn0004647 Drosophila Cell Line and Developmental Stage Gene and Exon Scores CME L1 1229.0
FBgn0004647 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Sg4 1667.0
FBgn0004647 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD11 733.0
FBgn0004647 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD20-c2 629.0
FBgn0004647 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD20-c5 239.0
FBgn0004647 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Kc167 322.0
FBgn0004647 Drosophila Cell Line and Developmental Stage Gene and Exon Scores GM2 1117.0
FBgn0004647 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S2-DRSC 3233.0
FBgn0004647 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S2R+ 562.0
FBgn0004647 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S1 1466.0
FBgn0004647 Drosophila Cell Line and Developmental Stage Gene and Exon Scores 1182-4H 781.0
FBgn0004647 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD16-c3 314.0
FBgn0004647 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD32 882.0
FBgn0004647 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD17-c3 822.0
FBgn0004647 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD8 1376.0
FBgn0004647 Drosophila Cell Line and Developmental Stage Gene and Exon Scores CME W1 Cl.8+ 1847.0
FBgn0004647 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD9 1917.0
FBgn0004647 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmBG1-c1 547.0
FBgn0004647 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD21 916.0
FBgn0004647 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD4-c1 1937.0
FBgn0004647 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmBG3-c2 3018.0
FBgn0004647 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S3 481.0
FBgn0004647 Drosophila Cell Line and Developmental Stage Gene and Exon Scores CME W2 1060.0
FBgn0004647 Drosophila Cell Line and Developmental Stage Gene and Exon Scores mbn2 85.0
FBgn0004647 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmBG2-c2 679.0
FBgn0004647 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 0-2 h 2946.0
FBgn0004647 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 2-4 h 2883.0
FBgn0004647 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 4-6 h 3996.0
FBgn0004647 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 6-8 h 3202.0
FBgn0004647 Drosophila Cell Line and Developmental Stage Gene and Exon Scores emb 8-10h 3454.0

9 Introns

DB identifier
Organism . Name
intron_FBgn0004647:1_FBgn0004647:2 Drosophila melanogaster
intron_FBgn0004647:2_FBgn0004647:3 Drosophila melanogaster
intron_FBgn0004647:3_FBgn0004647:4 Drosophila melanogaster
intron_FBgn0004647:4_FBgn0004647:5 Drosophila melanogaster
intron_FBgn0004647:5_FBgn0004647:6 Drosophila melanogaster
intron_FBgn0004647:6_FBgn0004647:7 Drosophila melanogaster
intron_FBgn0004647:7_FBgn0004647:8 Drosophila melanogaster
intron_FBgn0004647:8_FBgn0004647:10 Drosophila melanogaster
intron_FBgn0004647:8_FBgn0004647:9 Drosophila melanogaster

57 RNAi Results

Screen Gene Phenotype Score Conditions PubMed ID
Lipid storage N none 0.360984741   19067489
Lipid storage N none 0.818661042   19067489
Neural outgrowth N Excess branching np   18604272
Cell size and cell-cycle regulation (1) N none sp   16496002
Cell size and cell-cycle regulation (1) N none sp   16496002
NFAT signaling N Decreased NFAT translocation 2   16511445
Embryonic nervous system development N Defects in nervous system development np   15534205
Heart development and function N Heart patterning defects np   14684833
Dendrite pattern formation N none np   16547170
Combinatorial effect with methyl methanesulphonate (2) N none sp   19543366
Muscle morphogenesis and function (1) N Flightless np   20220848
Muscle morphogenesis and function (1) N Lethal np   20220848
Muscle morphogenesis and function (1) N Lethal np   20220848
Muscle morphogenesis and function (2) N Wing posture / locomotion / ability to fly defect or lethal / semi-lethal np   20220848
Muscle morphogenesis and function (4) N none np   20220848
Heat nociception (1) N none -1.17   21074052
Heat nociception (1) N none -1.17   21074052
Heart development and function (1) N none 1   20371351
Heart development and function (1) N none 1   20371351
Serratia marcescens infection (1) N none 1.6774193548387   19520911
Notch pathway regulation (1) N Lethal lethal temperature: 18 19363474
Notch pathway regulation (1) N none no phenotype temperature: 18 19363474
Notch pathway regulation (1) N Lethal lethal temperature: 25 19363474
Notch pathway regulation (1) N Lethal, escapers mild gain of bristles lethal temperature: 25 19363474
Notch pathway regulation (1) N Lethal lethal temperature: 29 19363474
Notch pathway regulation (1) N Lethal, escapers no phenotype lethal temperature: 29 19363474
Notch pathway regulation (2) N Gain of bristles, m only medium to strong temperature: 18 19363474
Notch pathway regulation (2) N Lethal lethal temperature: 29 19363474
Notch pathway regulation (2) N Lethal lethal temperature: 25 19363474
Notch pathway regulation (2) N Lethal, escapers mild gain of bristles lethal temperature: 29 19363474

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