Genomics
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713 Alleles
91 Clones
10 Exons
| DB identifier | Symbol |
|---|---|
| FBgn0004647:1 | N:1 |
| FBgn0004647:2 | N:2 |
| FBgn0004647:3 | N:3 |
| FBgn0004647:4 | N:4 |
| FBgn0004647:5 | N:5 |
| FBgn0004647:6 | N:6 |
| FBgn0004647:7 | N:7 |
| FBgn0004647:8 | N:8 |
| FBgn0004647:10 | N:10 |
| FBgn0004647:9 | N:9 |
4 UTRs
| Class | DB identifier |
Organism . Name |
|---|---|---|
| FivePrimeUTR | FBtr0070507-5-prime-utr | Drosophila melanogaster |
| FivePrimeUTR | FBtr0304659-5-prime-utr | Drosophila melanogaster |
| ThreePrimeUTR | FBtr0070507-3-prime-utr | Drosophila melanogaster |
| ThreePrimeUTR | FBtr0304659-3-prime-utr | Drosophila melanogaster |
Other
30 Pathways
- Signaling by NOTCH1 in Cancer,
- Pre-NOTCH Processing in the Endoplasmic Reticulum,
- Signaling by NOTCH2,
- Regulation of beta-cell development,
- Signaling by NOTCH4,
- Activated NOTCH1 Transmits Signal to the Nucleus,
- Loss of Function of FBXW7 in Cancer and NOTCH1 Signaling,
- Constitutive Signaling by NOTCH1 PEST Domain Mutants,
- Signaling by NOTCH1 PEST Domain Mutants in Cancer,
- Signaling by NOTCH1 HD Domain Mutants in Cancer,
- Constitutive Signaling by NOTCH1 HD Domain Mutants,
- Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant,
- A third proteolytic cleavage releases NICD,
- Pre-NOTCH Processing in Golgi,
- Signaling by NOTCH3,
- Developmental Biology,
- Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants,
- Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells,
- Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor,
- NOTCH2 Activation and Transmission of Signal to the Nucleus,
- NICD traffics to nucleus,
- Disease,
- NOTCH1 Intracellular Domain Regulates Transcription,
- Signaling by NOTCH1,
- FBXW7 Mutants and NOTCH1 in Cancer,
- Signaling by NOTCH,
- Signaling Pathways,
- Constitutive Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant,
- Pre-NOTCH Expression and Processing,
- Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer
2 Cross References
| Identifier |
Source . Name |
Subject . Primary Identifier |
|---|---|---|
| 31293 | NCBI Entrez Gene identifiers | FBgn0004647 |
| 57823 | BioGRID | FBgn0004647 |
11 Data Sets
| Name | URL |
|---|---|
| FlyBase data set for Drosophila melanogaster | |
| Swiss-Prot data set | http://ca.expasy.org/sprot |
| Drosophila 12 Genomes Consortium homology | |
| GenomeRNAi data set | |
| TreeFam data set | |
| Panther data set | |
| IntAct interactions data set | |
| BioGRID interaction data set | http://www.thebiogrid.org/downloads.php |
| GO Annotation from FlyBase | |
| FlyBase fasta data set for Drosophila melanogaster | |
| Drosophila Cell Line and Developmental Stage Gene and Exon Scores |
55 Expression Scores
9 Introns
57 RNAi Results
| Screen | Gene | Phenotype | Score | Conditions | PubMed ID |
|---|---|---|---|---|---|
| Lipid storage | N | none | 0.360984741 | 19067489 | |
| Lipid storage | N | none | 0.818661042 | 19067489 | |
| Neural outgrowth | N | Excess branching | np | 18604272 | |
| Cell size and cell-cycle regulation (1) | N | none | sp | 16496002 | |
| Cell size and cell-cycle regulation (1) | N | none | sp | 16496002 | |
| NFAT signaling | N | Decreased NFAT translocation | 2 | 16511445 | |
| Embryonic nervous system development | N | Defects in nervous system development | np | 15534205 | |
| Heart development and function | N | Heart patterning defects | np | 14684833 | |
| Dendrite pattern formation | N | none | np | 16547170 | |
| Combinatorial effect with methyl methanesulphonate (2) | N | none | sp | 19543366 | |
| Muscle morphogenesis and function (1) | N | Flightless | np | 20220848 | |
| Muscle morphogenesis and function (1) | N | Lethal | np | 20220848 | |
| Muscle morphogenesis and function (1) | N | Lethal | np | 20220848 | |
| Muscle morphogenesis and function (2) | N | Wing posture / locomotion / ability to fly defect or lethal / semi-lethal | np | 20220848 | |
| Muscle morphogenesis and function (4) | N | none | np | 20220848 | |
| Heat nociception (1) | N | none | -1.17 | 21074052 | |
| Heat nociception (1) | N | none | -1.17 | 21074052 | |
| Heart development and function (1) | N | none | 1 | 20371351 | |
| Heart development and function (1) | N | none | 1 | 20371351 | |
| Serratia marcescens infection (1) | N | none | 1.6774193548387 | 19520911 | |
| Notch pathway regulation (1) | N | Lethal | lethal | temperature: 18 | 19363474 |
| Notch pathway regulation (1) | N | none | no phenotype | temperature: 18 | 19363474 |
| Notch pathway regulation (1) | N | Lethal | lethal | temperature: 25 | 19363474 |
| Notch pathway regulation (1) | N | Lethal, escapers mild gain of bristles | lethal | temperature: 25 | 19363474 |
| Notch pathway regulation (1) | N | Lethal | lethal | temperature: 29 | 19363474 |
| Notch pathway regulation (1) | N | Lethal, escapers no phenotype | lethal | temperature: 29 | 19363474 |
| Notch pathway regulation (2) | N | Gain of bristles, m only | medium to strong | temperature: 18 | 19363474 |
| Notch pathway regulation (2) | N | Lethal | lethal | temperature: 29 | 19363474 |
| Notch pathway regulation (2) | N | Lethal | lethal | temperature: 25 | 19363474 |
| Notch pathway regulation (2) | N | Lethal, escapers mild gain of bristles | lethal | temperature: 29 | 19363474 |
