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Gene : yki D. melanogaster

DB identifier  ? FBgn0034970 Secondary Identifier  ? CG4005
Name  ? yorkie Source  FlyBase
  • synonyms:
  • FBgn0034970,
  • Yorkie,
  • YKI,
  • YAP,
  • FBan0004005,
  • CG4005

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68 Alleles

DB identifier Symbol Allele Class Organism
FBal0264249 yki[S168A.Scer\UAS.T:Disc\RFP]   Drosophila melanogaster
FBal0239889 yki[dsRNA.N.Scer\UAS]   Drosophila melanogaster
FBal0239890 yki[dsRNA.C.Scer\UAS]   Drosophila melanogaster
FBal0239891 yki[Scer\UAS.T:Zzzz\FLAG]   Drosophila melanogaster
FBal0239892 yki[Scer\UAS.T:Hsap\MYC]   Drosophila melanogaster
FBal0239893 yki[Scer\UAS.cZa]   Drosophila melanogaster
FBal0239894 yki[M1.Scer\UAS.T:Hsap\MYC]   Drosophila melanogaster
FBal0239895 yki[M2.Scer\UAS.T:Hsap\MYC]   Drosophila melanogaster
FBal0239896 yki[M3.Scer\UAS.T:Hsap\MYC]   Drosophila melanogaster
FBal0239897 yki[M12.Scer\UAS.T:Hsap\MYC]   Drosophila melanogaster
FBal0268101 yki[Delta.Scer\UAS]   Drosophila melanogaster
FBal0239898 yki[M123.Scer\UAS.T:Hsap\MYC]   Drosophila melanogaster
FBal0244975 yki[Scer\UAS.cRa.T:Hsap\MYC]   Drosophila melanogaster
FBal0244976 yki[S168A.Scer\UAS.cRa.T:Hsap\MYC]   Drosophila melanogaster
FBal0244978 yki[3SA.Scer\UAS.cRa.T:Hsap\MYC]   Drosophila melanogaster
FBal0244977 yki[S111A.S250A.Scer\UAS.cRa.T:Hsap\MYC]   Drosophila melanogaster
FBal0216282 yki[alphaTub84B.PH]   Drosophila melanogaster
FBal0260938 yki[W1W2.Scer\UAS]   Drosophila melanogaster
FBal0260939 yki[S97A.Scer\UAS]   Drosophila melanogaster
FBal0264931 yki[R310X]   Drosophila melanogaster
FBal0264932 yki[E271K]   Drosophila melanogaster
FBal0264933 yki[Y282N]   Drosophila melanogaster
FBal0264934 yki[P295S]   Drosophila melanogaster
FBal0264935 yki[G347R]   Drosophila melanogaster
FBal0264936 yki[F351I]   Drosophila melanogaster
FBal0264937 yki[P88L]   Drosophila melanogaster
FBal0185657 yki[f06249]   Drosophila melanogaster
FBal0191484 yki[Delta.w]   Drosophila melanogaster
FBal0263077 yki[HMS00041]   Drosophila melanogaster
FBal0192106 yki[GMR.PH]   Drosophila melanogaster

60 Clones

Secondary Identifier DB identifier
EK092110 FBcl0007206
EK149546 FBcl0007218
EK233751 FBcl0007228
EP01054 FBcl0076261
EP13331 FBcl0076363
GH14114 FBcl0129271
LD38548 FBcl0175664
LD36972 FBcl0175728
LD21311 FBcl0175861
LP06995 FBcl0188850
LP01370 FBcl0188940
LP04779 FBcl0188948
LP15346 FBcl0188951
LP01119 FBcl0188955
LP08432 FBcl0188994
LP04136 FBcl0189107
LP13453 FBcl0189109
RE37695 FBcl0227912
RE33590 FBcl0228735
RE06409 FBcl0228863
RE69979 FBcl0228866
RE63188 FBcl0228976
RE64373 FBcl0228978
RE65955 FBcl0229254
RE73160 FBcl0229255
RE03771 FBcl0229259
SD26638 FBcl0277930
SD25730 FBcl0277952
SD05370 FBcl0277956
SD04845 FBcl0277959

7 Exons

DB identifier Symbol
FBgn0034970:7 yki:7
FBgn0034970:5 yki:5
FBgn0034970:4 yki:4
FBgn0034970:3 yki:3
FBgn0034970:2 yki:2
FBgn0034970:1 yki:1
FBgn0034970:6 yki:6

3 Transcripts

DB identifier Gene
FBtr0309372 yki
FBtr0290256 yki
FBtr0290258 yki

6 UTRs

Class DB identifier
Organism . Name
FivePrimeUTR FBtr0309372-5-prime-utr Drosophila melanogaster
FivePrimeUTR FBtr0290256-5-prime-utr Drosophila melanogaster
FivePrimeUTR FBtr0290258-5-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0309372-3-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0290256-3-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0290258-3-prime-utr Drosophila melanogaster

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2 Cross References

Identifier
Source . Name

Subject . Primary Identifier
37851 NCBI Entrez Gene identifiers FBgn0034970
63430 BioGRID FBgn0034970

11 Data Sets

Name URL
FlyBase data set for Drosophila melanogaster  
Swiss-Prot data set http://ca.expasy.org/sprot
Drosophila 12 Genomes Consortium homology  
GenomeRNAi data set  
TreeFam data set  
Panther data set  
IntAct interactions data set  
BioGRID interaction data set http://www.thebiogrid.org/downloads.php
GO Annotation from FlyBase  
FlyBase fasta data set for Drosophila melanogaster  
Drosophila Cell Line and Developmental Stage Gene and Exon Scores  

55 Expression Scores


Gene . Primary Identifier

Submission . Title

Cell Line . Name

Developmental Stage . Name
Score
FBgn0034970 Drosophila Cell Line and Developmental Stage Gene and Exon Scores CME L1 6382.0
FBgn0034970 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Sg4 7437.0
FBgn0034970 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD11 5301.0
FBgn0034970 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD20-c2 6221.0
FBgn0034970 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD20-c5 6730.0
FBgn0034970 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Kc167 6641.0
FBgn0034970 Drosophila Cell Line and Developmental Stage Gene and Exon Scores GM2 6046.0
FBgn0034970 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S2-DRSC 6727.0
FBgn0034970 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S2R+ 9587.0
FBgn0034970 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S1 6270.0
FBgn0034970 Drosophila Cell Line and Developmental Stage Gene and Exon Scores 1182-4H 5034.0
FBgn0034970 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD16-c3 5965.0
FBgn0034970 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD32 5290.0
FBgn0034970 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD17-c3 8306.0
FBgn0034970 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD8 8193.0
FBgn0034970 Drosophila Cell Line and Developmental Stage Gene and Exon Scores CME W1 Cl.8+ 6185.0
FBgn0034970 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD9 6061.0
FBgn0034970 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmBG1-c1 5730.0
FBgn0034970 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD21 5200.0
FBgn0034970 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD4-c1 4773.0
FBgn0034970 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmBG3-c2 8353.0
FBgn0034970 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S3 4123.0
FBgn0034970 Drosophila Cell Line and Developmental Stage Gene and Exon Scores CME W2 5874.0
FBgn0034970 Drosophila Cell Line and Developmental Stage Gene and Exon Scores mbn2 5124.0
FBgn0034970 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmBG2-c2 4877.0
FBgn0034970 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 0-2 h 8121.0
FBgn0034970 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 2-4 h 7825.0
FBgn0034970 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 4-6 h 6219.0
FBgn0034970 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 6-8 h 5639.0
FBgn0034970 Drosophila Cell Line and Developmental Stage Gene and Exon Scores emb 8-10h 6881.0

7 Introns

DB identifier
Organism . Name
intron_FBgn0034970:7_FBgn0034970:5 Drosophila melanogaster
intron_FBgn0034970:5_FBgn0034970:4 Drosophila melanogaster
intron_FBgn0034970:4_FBgn0034970:3 Drosophila melanogaster
intron_FBgn0034970:3_FBgn0034970:2 Drosophila melanogaster
intron_FBgn0034970:2_FBgn0034970:1 Drosophila melanogaster
intron_FBgn0034970:6_FBgn0034970:4 Drosophila melanogaster
intron_FBgn0034970:4_FBgn0034970:2 Drosophila melanogaster

20 RNAi Results

Screen Gene Phenotype Score Conditions PubMed ID
Lipid storage yki none -1.161495965   19067489
Lipid storage yki none -1.723330307   19067489
Cell size and cell-cycle regulation (1) yki none sp   16496002
Muscle morphogenesis and function (1) yki none np   20220848
Serratia marcescens infection (1) yki none 0.976470588235294   19520911
Notch pathway regulation (4) yki Completely lethal (pupal) sp   19363474
Notch pathway regulation (1) yki Upregulation of Notch pathway np   20493818
Notch pathway regulation (2) yki Downregulation of Notch pathway sp C96-GAL4 20493818
Notch pathway regulation (2) yki Downregulation of Notch pathway; adult wing margin: notches sp C96-GAL4 20493818
Notch pathway regulation (2) yki Up- and downregulation of Notch pathway; wing disc NRE:EGFP: up, down, broader; wing disc myrRFP: accumulation; lethal sp en-GAL4 20493818
Notch pathway regulation (2) yki Upregulation of Notch pathway; wing disc NRE:EGFP: up sp en-GAL4 20493818
Notch pathway regulation (2) yki Lethal strong en-GAL4 20493818
Notch pathway regulation (2) yki Lethal strong en-GAL4 20493818
Adiposity regulation (1) yki none -0.209   20074523
RTK-Ras-ERK pathway regulation (1) yki none -0.36 0 minutes EGF stimulation 22028469
RTK-Ras-ERK pathway regulation (1) yki none 0.15 10 minutes EGF stimulation 22028469
RTK-Ras-ERK pathway regulation (2) yki none 0.87 10 minutes sSpitz stimulation 22028469
RTK-Ras-ERK pathway regulation (2) yki Increased ERK phosphorylation after sSpitz and EGF stimulation 2.65 30 minutes sSpitz stimulation 22028469
Hippo pathway regulation yki Upregulation of Hippo pathway -5.86   23263283
Glycosylation regulation (1) yki none sp   21203496

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