Genomics
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68 Alleles
60 Clones
7 Exons
| DB identifier | Symbol |
|---|---|
| FBgn0034970:7 | yki:7 |
| FBgn0034970:5 | yki:5 |
| FBgn0034970:4 | yki:4 |
| FBgn0034970:3 | yki:3 |
| FBgn0034970:2 | yki:2 |
| FBgn0034970:1 | yki:1 |
| FBgn0034970:6 | yki:6 |
6 UTRs
| Class | DB identifier |
Organism . Name |
|---|---|---|
| FivePrimeUTR | FBtr0309372-5-prime-utr | Drosophila melanogaster |
| FivePrimeUTR | FBtr0290256-5-prime-utr | Drosophila melanogaster |
| FivePrimeUTR | FBtr0290258-5-prime-utr | Drosophila melanogaster |
| ThreePrimeUTR | FBtr0309372-3-prime-utr | Drosophila melanogaster |
| ThreePrimeUTR | FBtr0290256-3-prime-utr | Drosophila melanogaster |
| ThreePrimeUTR | FBtr0290258-3-prime-utr | Drosophila melanogaster |
Other
32 Pathways
- Metabolism,
- YAP1- and WWTR1 (TAZ)-stimulated gene expression,
- Signaling Pathways,
- TGFBR2 MSI Frameshift Mutants in Cancer,
- SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription,
- TGFBR1 KD Mutants in Cancer,
- Generic Transcription Pathway,
- Nuclear signaling by ERBB4,
- PPARA Activates Gene Expression,
- TGFBR1 LBD Mutants in Cancer,
- Regulation of Lipid Metabolism by Peroxisome proliferator-activated receptor alpha (PPARalpha),
- Signaling by NODAL,
- Loss of Function of TGFBR1 in Cancer,
- Signaling by TGF-beta Receptor Complex,
- Disease,
- Fatty acid, triacylglycerol, and ketone body metabolism,
- TGFBR2 Kinase Domain Mutants in Cancer,
- Gene Expression,
- Signaling by TGF-beta Receptor Complex in Cancer,
- Developmental Biology,
- SMAD2/3 Phosphorylation Motif Mutants in Cancer,
- TGF-beta receptor signaling activates SMADs,
- Loss of Function of SMAD4 in Cancer,
- SMAD2/3 MH2 Domain Mutants in Cancer,
- Signaling by ERBB4,
- Loss of Function of SMAD2/3 in Cancer,
- Loss of Function of TGFBR2 in Cancer,
- Signaling by Activin,
- Signaling by Hippo,
- SMAD4 MH2 Domain Mutants in Cancer,
- Metabolism of lipids and lipoproteins,
- Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer
2 Cross References
| Identifier |
Source . Name |
Subject . Primary Identifier |
|---|---|---|
| 37851 | NCBI Entrez Gene identifiers | FBgn0034970 |
| 63430 | BioGRID | FBgn0034970 |
11 Data Sets
| Name | URL |
|---|---|
| FlyBase data set for Drosophila melanogaster | |
| Swiss-Prot data set | http://ca.expasy.org/sprot |
| Drosophila 12 Genomes Consortium homology | |
| GenomeRNAi data set | |
| TreeFam data set | |
| Panther data set | |
| IntAct interactions data set | |
| BioGRID interaction data set | http://www.thebiogrid.org/downloads.php |
| GO Annotation from FlyBase | |
| FlyBase fasta data set for Drosophila melanogaster | |
| Drosophila Cell Line and Developmental Stage Gene and Exon Scores |
55 Expression Scores
7 Introns
20 RNAi Results
| Screen | Gene | Phenotype | Score | Conditions | PubMed ID |
|---|---|---|---|---|---|
| Lipid storage | yki | none | -1.161495965 | 19067489 | |
| Lipid storage | yki | none | -1.723330307 | 19067489 | |
| Cell size and cell-cycle regulation (1) | yki | none | sp | 16496002 | |
| Muscle morphogenesis and function (1) | yki | none | np | 20220848 | |
| Serratia marcescens infection (1) | yki | none | 0.976470588235294 | 19520911 | |
| Notch pathway regulation (4) | yki | Completely lethal (pupal) | sp | 19363474 | |
| Notch pathway regulation (1) | yki | Upregulation of Notch pathway | np | 20493818 | |
| Notch pathway regulation (2) | yki | Downregulation of Notch pathway | sp | C96-GAL4 | 20493818 |
| Notch pathway regulation (2) | yki | Downregulation of Notch pathway; adult wing margin: notches | sp | C96-GAL4 | 20493818 |
| Notch pathway regulation (2) | yki | Up- and downregulation of Notch pathway; wing disc NRE:EGFP: up, down, broader; wing disc myrRFP: accumulation; lethal | sp | en-GAL4 | 20493818 |
| Notch pathway regulation (2) | yki | Upregulation of Notch pathway; wing disc NRE:EGFP: up | sp | en-GAL4 | 20493818 |
| Notch pathway regulation (2) | yki | Lethal | strong | en-GAL4 | 20493818 |
| Notch pathway regulation (2) | yki | Lethal | strong | en-GAL4 | 20493818 |
| Adiposity regulation (1) | yki | none | -0.209 | 20074523 | |
| RTK-Ras-ERK pathway regulation (1) | yki | none | -0.36 | 0 minutes EGF stimulation | 22028469 |
| RTK-Ras-ERK pathway regulation (1) | yki | none | 0.15 | 10 minutes EGF stimulation | 22028469 |
| RTK-Ras-ERK pathway regulation (2) | yki | none | 0.87 | 10 minutes sSpitz stimulation | 22028469 |
| RTK-Ras-ERK pathway regulation (2) | yki | Increased ERK phosphorylation after sSpitz and EGF stimulation | 2.65 | 30 minutes sSpitz stimulation | 22028469 |
| Hippo pathway regulation | yki | Upregulation of Hippo pathway | -5.86 | 23263283 | |
| Glycosylation regulation (1) | yki | none | sp | 21203496 |
