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Gene : lz D. melanogaster

DB identifier  ? FBgn0002576 Secondary Identifier  ? CG1689
Name  ? lozenge Source  FlyBase
  • synonyms:
  • CG1689,
  • amx,
  • FBan0001689,
  • spectacled,
  • Lozenge,
  • FBgn0002576,
  • spe,
  • fs(1)A1569,
  • fs(1)M69,
  • Lz

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161 Alleles

DB identifier Symbol Allele Class Organism
FBal0267319 lz[4B4]   Drosophila melanogaster
FBal0284252 lz[T:Avic\GFP-SF,T:Zzzz\FLAG,T:Zzzz\PSP.CS,T:Zzzz\TEV.CS,T:Zzzz\BLRP]   Drosophila melanogaster
FBal0276922 lz[Scer\UAS.cSa]   Drosophila melanogaster
FBal0212513 lz[MB01646]   Drosophila melanogaster
FBal0046099 lz[gal4]   Drosophila melanogaster
FBal0046100 lz[A27.1F1]   Drosophila melanogaster
FBal0061066 lz[L] amorphic allele - genetic evidence Drosophila melanogaster
FBal0050114 lz[Sprite] gain of function allele Drosophila melanogaster
FBal0011762 lz[1]   Drosophila melanogaster
FBal0011773 lz[34]   Drosophila melanogaster
FBal0011810 lz[75v]   Drosophila melanogaster
FBal0011825 lz[K] hypomorphic allele - genetic evidence Drosophila melanogaster
FBal0051364 lz[pm2]   Drosophila melanogaster
FBal0063890 lz[mr2]   Drosophila melanogaster
FBal0189551 lz[Scer\UAS.T:Rep-en]   Drosophila melanogaster
FBal0150351 lz[+94h24-3]   Drosophila melanogaster
FBal0011801 lz[61f]   Drosophila melanogaster
FBal0035196 lz[12-4669]   Drosophila melanogaster
FBal0011778 lz[37]   Drosophila melanogaster
FBal0011812 lz[491]   Drosophila melanogaster
FBal0092631 lz[50j]   Drosophila melanogaster
FBal0050113 lz[GMR.PD]   Drosophila melanogaster
FBal0050124 lz[sEc3.5]   Drosophila melanogaster
FBal0028412 lz[G2]   Drosophila melanogaster
FBal0092630 lz[hb]   Drosophila melanogaster
FBal0092626 lz[mF4]   Drosophila melanogaster
FBal0092627 lz[mF3]   Drosophila melanogaster
FBal0092628 lz[mF2]   Drosophila melanogaster
FBal0092629 lz[mF1]   Drosophila melanogaster
FBal0094396 lz[hs.PD]   Drosophila melanogaster

5 Clones

Secondary Identifier DB identifier
EP19329 FBcl0077555
EK048561 FBcl0116556
RH62791 FBcl0240072
CK01.61C.H2 FBcl0415300
273541 FBcl0415338

6 Exons

DB identifier Symbol
FBgn0002576:1 lz:1
FBgn0002576:2 lz:2
FBgn0002576:3 lz:3
FBgn0002576:4 lz:4
FBgn0002576:5 lz:5
FBgn0002576:6 lz:6

2 Transcripts

DB identifier Gene
FBtr0071320 lz
FBtr0112814 lz

4 UTRs

Class DB identifier
Organism . Name
FivePrimeUTR FBtr0071320-5-prime-utr Drosophila melanogaster
FivePrimeUTR FBtr0112814-5-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0071320-3-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0112814-3-prime-utr Drosophila melanogaster

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2 Cross References

Identifier
Source . Name

Subject . Primary Identifier
31883 NCBI Entrez Gene identifiers FBgn0002576
58331 BioGRID FBgn0002576

11 Data Sets

Name URL
FlyBase data set for Drosophila melanogaster  
Swiss-Prot data set http://ca.expasy.org/sprot
Drosophila 12 Genomes Consortium homology  
GenomeRNAi data set  
TreeFam data set  
Panther data set  
IntAct interactions data set  
BioGRID interaction data set http://www.thebiogrid.org/downloads.php
GO Annotation from FlyBase  
FlyBase fasta data set for Drosophila melanogaster  
Drosophila Cell Line and Developmental Stage Gene and Exon Scores  

55 Expression Scores


Gene . Primary Identifier

Submission . Title

Cell Line . Name

Developmental Stage . Name
Score
FBgn0002576 Drosophila Cell Line and Developmental Stage Gene and Exon Scores CME L1 195.0
FBgn0002576 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Sg4 42.0
FBgn0002576 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD11 296.0
FBgn0002576 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD20-c2 280.0
FBgn0002576 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD20-c5 165.0
FBgn0002576 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Kc167 40.0
FBgn0002576 Drosophila Cell Line and Developmental Stage Gene and Exon Scores GM2 215.0
FBgn0002576 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S2-DRSC 389.0
FBgn0002576 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S2R+ 152.0
FBgn0002576 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S1 110.0
FBgn0002576 Drosophila Cell Line and Developmental Stage Gene and Exon Scores 1182-4H 77.0
FBgn0002576 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD16-c3 190.0
FBgn0002576 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD32 242.0
FBgn0002576 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD17-c3 151.0
FBgn0002576 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD8 83.0
FBgn0002576 Drosophila Cell Line and Developmental Stage Gene and Exon Scores CME W1 Cl.8+ 119.0
FBgn0002576 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD9 109.0
FBgn0002576 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmBG1-c1 127.0
FBgn0002576 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD21 164.0
FBgn0002576 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD4-c1 115.0
FBgn0002576 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmBG3-c2 136.0
FBgn0002576 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S3 42.0
FBgn0002576 Drosophila Cell Line and Developmental Stage Gene and Exon Scores CME W2 133.0
FBgn0002576 Drosophila Cell Line and Developmental Stage Gene and Exon Scores mbn2 101.0
FBgn0002576 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmBG2-c2 43.0
FBgn0002576 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 0-2 h 304.0
FBgn0002576 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 2-4 h 114.0
FBgn0002576 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 4-6 h 207.0
FBgn0002576 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 6-8 h 175.0
FBgn0002576 Drosophila Cell Line and Developmental Stage Gene and Exon Scores emb 8-10h 126.0

6 Introns

DB identifier
Organism . Name
intron_FBgn0002576:1_FBgn0002576:2 Drosophila melanogaster
intron_FBgn0002576:2_FBgn0002576:3 Drosophila melanogaster
intron_FBgn0002576:3_FBgn0002576:4 Drosophila melanogaster
intron_FBgn0002576:4_FBgn0002576:6 Drosophila melanogaster
intron_FBgn0002576:4_FBgn0002576:5 Drosophila melanogaster
intron_FBgn0002576:5_FBgn0002576:6 Drosophila melanogaster

17 RNAi Results

Screen Gene Phenotype Score Conditions PubMed ID
Lipid storage lz none 0.189041604   19067489
Lipid storage lz none 0.134858296   19067489
Lipid storage lz none 0.064069885   19067489
Lipid storage lz none 0.106750943   19067489
Lipid storage lz none -1.218976216   19067489
Lipid storage lz none 0.551680501   19067489
Lipid storage lz none 0.230419376   19067489
Insect dengue virus infection lz Inhibition of dengue virus propagation 25.6 (0.000038)   19396146
ERK signaling lz ERK activation reduced weak   17086199
Dendrite pattern formation lz none np   16547170
Mutant human huntingtin aggregation lz Decreased mutant human huntingtin aggregation <= -2   19789644
PGN-induced dJNK phosphorylation lz Increased P-JNK protein expression with PGN 3.47 15 min PGN induction 19893628
RTK-Ras-ERK pathway regulation (1) lz none -0.28 0 minutes EGF stimulation 22028469
RTK-Ras-ERK pathway regulation (1) lz Decreased ERK phosphorylation after EGF stimulation -1.7 10 minutes EGF stimulation 22028469
RTK-Ras-ERK pathway regulation (2) lz none 0.71 30 minutes sSpitz stimulation 22028469
RTK-Ras-ERK pathway regulation (2) lz none -0.79 10 minutes sSpitz stimulation 22028469
Hippo pathway regulation lz none 2.48   23263283

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