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Gene : Apc2 D. melanogaster

DB identifier  ? FBgn0026598 Secondary Identifier  ? CG6193
Name  ? Adenomatous polyposis coli tumor suppressor homolog 2 Source  FlyBase
  • synonyms:
  • APC2,
  • E-APC dAPC2,
  • APC,
  • Dm APC2,
  • D-APC2,
  • Adenomatous Polyposis Coli 2,
  • FBan0006193,
  • E-APC,
  • Epithelial Adenomatous Polyposis Coli,
  • FBgn0026598,
  • dAPC2,
  • CG6193,
  • dAPC2/E-APC

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61 Alleles

DB identifier Symbol Allele Class Organism
FBal0280776 Apc2[T:Avic\GFP-EGFP,T:Zzzz\Mito-actA]   Drosophila melanogaster
FBal0280777 Apc2[T:Avic\GFP-EGFP,T:Mmmm\c-Ha-Ras]   Drosophila melanogaster
FBal0267816 Apc2[WT.T:Avic\GFP-EGFP]   Drosophila melanogaster
FBal0280738 Apc2[DeltaR3.T:Avic\GFP-EGFP]   Drosophila melanogaster
FBal0280778 Apc2[T:Avic\GFP-EGFP,T:Hsap\CAAX]   Drosophila melanogaster
FBal0280779 Apc2[T:Myr-Src64B,T:Avic\GFP-EGFP]   Drosophila melanogaster
FBal0280739 Apc2[DeltaR1R4-R5.T:Avic\GFP-EGFP]   Drosophila melanogaster
FBal0280740 Apc2[DeltaR3-R5.T:Avic\GFP-EGFP]   Drosophila melanogaster
FBal0268076 Apc2[FL.T:Avic\GFP-EGFP]   Drosophila melanogaster
FBal0268077 Apc2[N-SAMP.T:Avic\GFP-EGFP]   Drosophila melanogaster
FBal0280741 Apc2[KeepR3.T:Avic\GFP-EGFP]   Drosophila melanogaster
FBal0268078 Apc2[DeltaC30.T:Avic\GFP-EGFP]   Drosophila melanogaster
FBal0280742 Apc2[Delta20.T:Avic\GFP-EGFP]   Drosophila melanogaster
FBal0280743 Apc2[Delta15.T:Avic\GFP-EGFP]   Drosophila melanogaster
FBal0280744 Apc2[Delta15Delta20.T:Avic\GFP-EGFP]   Drosophila melanogaster
FBal0280745 Apc2[DeltaR2.T:Avic\GFP-EGFP]   Drosophila melanogaster
FBal0280746 Apc2[DeltaB.T:Avic\GFP-EGFP]   Drosophila melanogaster
FBal0280747 Apc2[d40.T:Avic\GFP-EGFP]   Drosophila melanogaster
FBal0280748 Apc2[EndatB.T:Avic\GFP-EGFP]   Drosophila melanogaster
FBal0280749 Apc2[DeltaSAMP.T:Avic\GFP-EGFP]   Drosophila melanogaster
FBal0268241 Apc2[Delta15RDelta20RDeltaB.T:Avic\GFP-EGFP]   Drosophila melanogaster
FBal0268242 Apc2[Delta20RDeltaB.T:Avic\GFP-EGFP]   Drosophila melanogaster
FBal0268243 Apc2[R3-R5SA.T:Avic\GFP-EGFP]   Drosophila melanogaster
FBal0268244 Apc2[R3-R5SD.T:Avic\GFP-EGFP]   Drosophila melanogaster
FBal0268245 Apc2[R1-R5SA.T:Avic\GFP-EGFP]   Drosophila melanogaster
FBal0268246 Apc2[R1-R5SD.T:Avic\GFP-EGFP]   Drosophila melanogaster
FBal0268247 Apc2[R3-R5ExR.T:Avic\GFP-EGFP]   Drosophila melanogaster
FBal0268248 Apc2[R1-R5ExR.T:Avic\GFP-EGFP]   Drosophila melanogaster
FBal0162804 Apc2[c03232]   Drosophila melanogaster
FBal0264334 Apc2[Scer\UAS.T:Myr-Src64B,T:Zzzz\FLAG]   Drosophila melanogaster

136 Clones

Secondary Identifier DB identifier
UUGC1135 FBcl0006035
ESG015d.E21.1_E04 FBcl0006765
EP04036 FBcl0083487
EK057518 FBcl0119496
EK156262 FBcl0119510
EK105960 FBcl0119554
EK194510 FBcl0119582
EK046531 FBcl0119622
EK144310 FBcl0119768
GM10405 FBcl0142047
GM19011 FBcl0146664
LD18122 FBcl0156390
LD43120 FBcl0170104
LD37423 FBcl0170114
LD24920 FBcl0170194
LD31622 FBcl0170196
LD21721 FBcl0170209
RE58182 FBcl0213307
RE51917 FBcl0213341
RE56287 FBcl0213345
RE61539 FBcl0213379
SD01634 FBcl0285941
SD01652 FBcl0285945
SD01649 FBcl0285946
57455 FBcl0395347
Dmel_neb_016584_0939_0480 FBcl0370487
RM02251 FBcl0370480
RM02451 FBcl0370481
Dmel_dig_014905_0647_1355 FBcl0370485
Dmel_dig_005871_0659_2663 FBcl0370486

3 Exons

DB identifier Symbol
FBgn0026598:1 Apc2:1
FBgn0026598:2 Apc2:2
FBgn0026598:3 Apc2:3

1 Transcripts

DB identifier Gene
FBtr0084552 Apc2

2 UTRs

Class DB identifier
Organism . Name
FivePrimeUTR FBtr0084552-5-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0084552-3-prime-utr Drosophila melanogaster

Interactions

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Other

0 Pathways

2 Cross References

Identifier
Source . Name

Subject . Primary Identifier
42871 NCBI Entrez Gene identifiers FBgn0026598
67803 BioGRID FBgn0026598

11 Data Sets

Name URL
FlyBase data set for Drosophila melanogaster  
TrEMBL data set http://www.ebi.ac.uk/trembl/
Drosophila 12 Genomes Consortium homology  
GenomeRNAi data set  
TreeFam data set  
Panther data set  
IntAct interactions data set  
BioGRID interaction data set http://www.thebiogrid.org/downloads.php
GO Annotation from FlyBase  
FlyBase fasta data set for Drosophila melanogaster  
Drosophila Cell Line and Developmental Stage Gene and Exon Scores  

55 Expression Scores


Gene . Primary Identifier

Submission . Title

Cell Line . Name

Developmental Stage . Name
Score
FBgn0026598 Drosophila Cell Line and Developmental Stage Gene and Exon Scores CME L1 364.0
FBgn0026598 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Sg4 406.0
FBgn0026598 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD11 362.0
FBgn0026598 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD20-c2 256.0
FBgn0026598 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD20-c5 462.0
FBgn0026598 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Kc167 342.0
FBgn0026598 Drosophila Cell Line and Developmental Stage Gene and Exon Scores GM2 257.0
FBgn0026598 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S2-DRSC 339.0
FBgn0026598 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S2R+ 298.0
FBgn0026598 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S1 453.0
FBgn0026598 Drosophila Cell Line and Developmental Stage Gene and Exon Scores 1182-4H 553.0
FBgn0026598 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD16-c3 426.0
FBgn0026598 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD32 322.0
FBgn0026598 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD17-c3 316.0
FBgn0026598 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD8 429.0
FBgn0026598 Drosophila Cell Line and Developmental Stage Gene and Exon Scores CME W1 Cl.8+ 447.0
FBgn0026598 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD9 470.0
FBgn0026598 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmBG1-c1 340.0
FBgn0026598 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD21 317.0
FBgn0026598 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD4-c1 294.0
FBgn0026598 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmBG3-c2 440.0
FBgn0026598 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S3 512.0
FBgn0026598 Drosophila Cell Line and Developmental Stage Gene and Exon Scores CME W2 540.0
FBgn0026598 Drosophila Cell Line and Developmental Stage Gene and Exon Scores mbn2 438.0
FBgn0026598 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmBG2-c2 256.0
FBgn0026598 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 0-2 h 1524.0
FBgn0026598 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 2-4 h 1205.0
FBgn0026598 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 4-6 h 613.0
FBgn0026598 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 6-8 h 451.0
FBgn0026598 Drosophila Cell Line and Developmental Stage Gene and Exon Scores emb 8-10h 358.0

2 Introns

DB identifier
Organism . Name
intron_FBgn0026598:1_FBgn0026598:2 Drosophila melanogaster
intron_FBgn0026598:2_FBgn0026598:3 Drosophila melanogaster

17 RNAi Results

Screen Gene Phenotype Score Conditions PubMed ID
Lipid storage Apc2 none 0.320652738   19067489
Lipid storage Apc2 none 3.80354875   19067489
Cell size and cell-cycle regulation (1) Apc2 none sp   16496002
Muscle morphogenesis and function (1) Apc2 none np   20220848
Heat nociception (1) Apc2 none -0.2   21074052
Heart development and function (1) Apc2 none 1   20371351
Serratia marcescens infection (1) Apc2 none -0.982142857142857   19520911
Serratia marcescens infection (1) Apc2 none 0.347222222222222   19520911
Notch pathway regulation (4) Apc2 none 0   19363474
Notch pathway regulation (4) Apc2 none 0   19363474
Adiposity regulation (1) Apc2 Decreased triglyceride expression -0.439   20074523
Adiposity regulation (2) Apc2 none 0.031   20074523
Adiposity regulation (3) Apc2 none -0.021   20074523
Adiposity regulation (4) Apc2 none -0.212   20074523
Adiposity regulation (5) Apc2 none -0.026   20074523
Hippo pathway regulation Apc2 none -0.43   23263283
Muscle development and maintenance Apc2 none sp  

0 Submissions