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Gene : RhoGEF2 D. melanogaster
DB identifier  ? FBgn0023172 Secondary Identifier  ? CG9635
Name  ? Rho guanine nucleotide exchange factor 2 Source  FlyBase
  • synonyms:
  • DRhoGEF2,
  • Gef2,
  • unnamed,
  • FBgn0010569,
  • RhoGEF,
  • CG9635,
  • Rho-GEF2,
  • RhoGF2,
  • DRhoGEF,
  • shar,
  • FBgn0023172,
  • guanine nucleotide exchange factor 2,
  • FBgn0020519,
  • Transcription unit 2,
  • akkordion,
  • T2,
  • RhoGEF2,
  • Shar pei,
  • l(2)04291,
  • Su(Rho1)2B,
  • RG2,
  • FBan0009635
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42 Alleles

DB identifier Symbol Allele Class Organism
FBal0239203 RhoGEF2[NIG.9635R]   Drosophila melanogaster
FBal0181886 RhoGEF2[PX10] hypomorphic allele - genetic evidence Drosophila melanogaster
FBal0181885 RhoGEF2[PX6] hypomorphic allele - genetic evidence Drosophila melanogaster
FBal0245936 RhoGEF2[JF01747]   Drosophila melanogaster
FBal0258802 RhoGEF2[KK100719]   Drosophila melanogaster
FBal0008055 RhoGEF2[04291] loss of function allele Drosophila melanogaster
FBal0159891 RhoGEF2[e03784]   Drosophila melanogaster
FBal0130792 RhoGEF2[EP2432]   Drosophila melanogaster
FBal0159892 RhoGEF2[EY08391]   Drosophila melanogaster
FBal0257781 RhoGEF2[HMS01118]   Drosophila melanogaster
FBal0241120 RhoGEF2[Scer\UAS.cUa]   Drosophila melanogaster
FBal0102858 RhoGEF2[unspecified]   Drosophila melanogaster
FBal0085926 RhoGEF2[6.5] antimorphic allele - genetic evidence Drosophila melanogaster
FBal0085934 RhoGEF2[1.1] loss of function allele Drosophila melanogaster
FBal0085923 RhoGEF2[9.6]   Drosophila melanogaster
FBal0085933 RhoGEF2[2.3]   Drosophila melanogaster
FBal0085932 RhoGEF2[2.6]   Drosophila melanogaster
FBal0085929 RhoGEF2[4.4] loss of function allele Drosophila melanogaster
FBal0085931 RhoGEF2[2.9]   Drosophila melanogaster
FBal0181888 RhoGEF2[350]   Drosophila melanogaster
FBal0085927 RhoGEF2[5.2]   Drosophila melanogaster
FBal0085930 RhoGEF2[4.1] loss of function allele Drosophila melanogaster
FBal0085928 RhoGEF2[5.1] antimorphic allele - genetic evidence Drosophila melanogaster
FBal0181884 RhoGEF2[dsRNA.cRa]   Drosophila melanogaster
FBal0155962 RhoGEF2[11-3]   Drosophila melanogaster
FBal0085924 RhoGEF2[8.9]   Drosophila melanogaster
FBal0181889 RhoGEF2[201]   Drosophila melanogaster
FBal0085925 RhoGEF2[8.1]   Drosophila melanogaster
FBal0197757 RhoGEF2[PDZ.T:Avic\GFP]   Drosophila melanogaster
FBal0190069 RhoGEF2[DeltaPDZ.Scer\UAS.P\T.T:Uuuu\T7]   Drosophila melanogaster

63 Clones

Secondary Identifier DB identifier
EK270062 FBcl0004544
EK050001 FBcl0004892
EK004460 FBcl0005062
EK026135 FBcl0005074
EK202446 FBcl0005144
EK155046 FBcl0005164
EK054061 FBcl0005248
EK119828 FBcl0005258
EK187259 FBcl0005268
EK250237 FBcl0005292
CK01905 FBcl0059665
EP14805 FBcl0080963
EP09014 FBcl0080965
EP00155 FBcl0080969
EP14412 FBcl0080981
EP19737 FBcl0080987
EP05548 FBcl0081001
EN15654 FBcl0095533
GM25011 FBcl0145946
HL03229 FBcl0150490
RH56752 FBcl0271275
SD13768 FBcl0283263
SD04476 FBcl0283265
SD06759 FBcl0283274
SD10031 FBcl0283292
SD09362 FBcl0283297
SD14264 FBcl0283306
SD22588 FBcl0283309
EC056006 FBcl0301583
EC054547 FBcl0302236

27 Exons

DB identifier Symbol
FBgn0023172:2 RhoGEF2:2
FBgn0023172:3 RhoGEF2:3
FBgn0023172:4 RhoGEF2:4
FBgn0023172:5 RhoGEF2:5
FBgn0023172:6 RhoGEF2:6
FBgn0023172:7 RhoGEF2:7
FBgn0023172:8 RhoGEF2:8
FBgn0023172:11 RhoGEF2:11
FBgn0023172:12 RhoGEF2:12
FBgn0023172:13 RhoGEF2:13
FBgn0023172:14 RhoGEF2:14
FBgn0023172:15 RhoGEF2:15
FBgn0023172:16 RhoGEF2:16
FBgn0023172:17 RhoGEF2:17
FBgn0023172:18 RhoGEF2:18
FBgn0023172:20 RhoGEF2:20
FBgn0023172:21 RhoGEF2:21
FBgn0023172:22 RhoGEF2:22
FBgn0023172:23 RhoGEF2:23
FBgn0023172:24 RhoGEF2:24
FBgn0023172:25 RhoGEF2:25
FBgn0023172:26 RhoGEF2:26
FBgn0023172:27 RhoGEF2:27
FBgn0023172:9 RhoGEF2:9
FBgn0023172:1 RhoGEF2:1
FBgn0023172:19 RhoGEF2:19
FBgn0023172:10 RhoGEF2:10

5 Transcripts

DB identifier Gene
FBtr0086969 RhoGEF2
FBtr0086970 RhoGEF2
FBtr0305083 RhoGEF2
FBtr0086971 RhoGEF2
FBtr0340124 RhoGEF2

10 UTRs

Class DB identifier
Organism . Name
FivePrimeUTR FBtr0086969-5-prime-utr Drosophila melanogaster
FivePrimeUTR FBtr0086970-5-prime-utr Drosophila melanogaster
FivePrimeUTR FBtr0086971-5-prime-utr Drosophila melanogaster
FivePrimeUTR FBtr0340124-5-prime-utr Drosophila melanogaster
FivePrimeUTR FBtr0305083-5-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0086969-3-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0086970-3-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0086971-3-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0340124-3-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0305083-3-prime-utr Drosophila melanogaster

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12 Pathways

2 Cross References

Identifier
Source . Name
Subject . Primary Identifier
36915 NCBI Entrez Gene identifiers FBgn0023172
62615 BioGRID FBgn0023172

10 Data Sets

Name URL
FlyBase data set for Drosophila melanogaster  
TrEMBL data set http://www.ebi.ac.uk/trembl/
Drosophila 12 Genomes Consortium homology  
GenomeRNAi data set  
TreeFam data set  
IntAct interactions data set  
BioGRID interaction data set http://www.thebiogrid.org/downloads.php
GO Annotation from FlyBase  
FlyBase fasta data set for Drosophila melanogaster  
Drosophila Cell Line and Developmental Stage Gene and Exon Scores  

55 Expression Scores


Gene . Primary Identifier
Submission . Title
Cell Line . Name
Developmental Stage . Name 		Score
FBgn0023172 Drosophila Cell Line and Developmental Stage Gene and Exon Scores CME L1 1344.0
FBgn0023172 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Sg4 1751.0
FBgn0023172 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD11 1909.0
FBgn0023172 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD20-c2 2231.0
FBgn0023172 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD20-c5 2479.0
FBgn0023172 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Kc167 595.0
FBgn0023172 Drosophila Cell Line and Developmental Stage Gene and Exon Scores GM2 2799.0
FBgn0023172 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S2-DRSC 1848.0
FBgn0023172 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S2R+ 2336.0
FBgn0023172 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S1 1995.0
FBgn0023172 Drosophila Cell Line and Developmental Stage Gene and Exon Scores 1182-4H 2522.0
FBgn0023172 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD16-c3 652.0
FBgn0023172 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD32 1619.0
FBgn0023172 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD17-c3 2054.0
FBgn0023172 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD8 1919.0
FBgn0023172 Drosophila Cell Line and Developmental Stage Gene and Exon Scores CME W1 Cl.8+ 1385.0
FBgn0023172 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD9 2613.0
FBgn0023172 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmBG1-c1 1931.0
FBgn0023172 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD21 1757.0
FBgn0023172 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD4-c1 1730.0
FBgn0023172 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmBG3-c2 1665.0
FBgn0023172 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S3 1906.0
FBgn0023172 Drosophila Cell Line and Developmental Stage Gene and Exon Scores CME W2 2075.0
FBgn0023172 Drosophila Cell Line and Developmental Stage Gene and Exon Scores mbn2 2090.0
FBgn0023172 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmBG2-c2 2681.0
FBgn0023172 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 0-2 h 4327.0
FBgn0023172 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 2-4 h 1654.0
FBgn0023172 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 4-6 h 2063.0
FBgn0023172 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 6-8 h 2063.0
FBgn0023172 Drosophila Cell Line and Developmental Stage Gene and Exon Scores emb 8-10h 1558.0

29 Introns

DB identifier
Organism . Name
intron_FBgn0023172:1_FBgn0023172:3 Drosophila melanogaster
intron_FBgn0023172:3_FBgn0023172:4 Drosophila melanogaster
intron_FBgn0023172:4_FBgn0023172:5 Drosophila melanogaster
intron_FBgn0023172:5_FBgn0023172:6 Drosophila melanogaster
intron_FBgn0023172:6_FBgn0023172:7 Drosophila melanogaster
intron_FBgn0023172:7_FBgn0023172:8 Drosophila melanogaster
intron_FBgn0023172:8_FBgn0023172:10 Drosophila melanogaster
intron_FBgn0023172:10_FBgn0023172:11 Drosophila melanogaster
intron_FBgn0023172:11_FBgn0023172:12 Drosophila melanogaster
intron_FBgn0023172:12_FBgn0023172:13 Drosophila melanogaster
intron_FBgn0023172:13_FBgn0023172:14 Drosophila melanogaster
intron_FBgn0023172:14_FBgn0023172:15 Drosophila melanogaster
intron_FBgn0023172:15_FBgn0023172:16 Drosophila melanogaster
intron_FBgn0023172:16_FBgn0023172:17 Drosophila melanogaster
intron_FBgn0023172:17_FBgn0023172:18 Drosophila melanogaster
intron_FBgn0023172:18_FBgn0023172:20 Drosophila melanogaster
intron_FBgn0023172:20_FBgn0023172:21 Drosophila melanogaster
intron_FBgn0023172:21_FBgn0023172:22 Drosophila melanogaster
intron_FBgn0023172:22_FBgn0023172:23 Drosophila melanogaster
intron_FBgn0023172:23_FBgn0023172:24 Drosophila melanogaster
intron_FBgn0023172:24_FBgn0023172:25 Drosophila melanogaster
intron_FBgn0023172:25_FBgn0023172:26 Drosophila melanogaster
intron_FBgn0023172:26_FBgn0023172:27 Drosophila melanogaster
intron_FBgn0023172:2_FBgn0023172:3 Drosophila melanogaster
intron_FBgn0023172:8_FBgn0023172:11 Drosophila melanogaster
intron_FBgn0023172:8_FBgn0023172:9 Drosophila melanogaster
intron_FBgn0023172:9_FBgn0023172:11 Drosophila melanogaster
intron_FBgn0023172:17_FBgn0023172:19 Drosophila melanogaster
intron_FBgn0023172:19_FBgn0023172:20 Drosophila melanogaster

10 RNAi Results

Screen Gene Phenotype Score Conditions PubMed ID
Lipid storage RhoGEF2 none -0.654763926   19067489
Cell size and cell-cycle regulation (1) RhoGEF2 none sp   16496002
Cell size and cell-cycle regulation (1) RhoGEF2 none sp   16496002
Lipid storage RhoGEF2 Altered mean signal automated analysis   18408709
RTK-Ras-ERK pathway regulation (1) RhoGEF2 none -0.58 10 minutes EGF stimulation 22028469
RTK-Ras-ERK pathway regulation (1) RhoGEF2 none -1 0 minutes EGF stimulation 22028469
RTK-Ras-ERK pathway regulation (2) RhoGEF2 none 0.84 10 minutes sSpitz stimulation 22028469
RTK-Ras-ERK pathway regulation (2) RhoGEF2 Increased ERK phosphorylation after sSpitz and EGF stimulation 1.55 30 minutes sSpitz stimulation 22028469
Wnt proteins secretion RhoGEF2 none -0.7   22094269
Glycosylation regulation (1) RhoGEF2 none sp   21203496

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