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Gene : tin D. melanogaster

DB identifier  ? FBgn0004110 Secondary Identifier  ? CG7895
Name  ? tinman Source  FlyBase
  • synonyms:
  • FBan0007895,
  • FBgn0002944,
  • DmNK-4,
  • FBgn0002850,
  • msh2,
  • NKX2.5,
  • msh-2,
  • NK-4,
  • FBgn0004110,
  • DROHOXNK4,
  • NK-4/msh-2,
  • Tinman,
  • muscle-specific-homeodomain-2,
  • TIN,
  • HOX,
  • DROHOXHK4,
  • NK4/msh-2,
  • CG7895,
  • tin/NK4,
  • NK4

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59 Alleles

DB identifier Symbol Allele Class Organism
FBal0035781 tin[142] hypomorphic allele - genetic evidence Drosophila melanogaster
FBal0140908 tin[DN.Scer\UAS.T:Rep-en]   Drosophila melanogaster
FBal0122884 tin[142Delta36]   Drosophila melanogaster
FBal0032862 tin[hs.PB]   Drosophila melanogaster
FBal0154445 tin[S-510S]   Drosophila melanogaster
FBal0060874 tin[+t10.7]   Drosophila melanogaster
FBal0154451 tin[F-96S]   Drosophila melanogaster
FBal0154440 tin[S-581F]   Drosophila melanogaster
FBal0154452 tin[F-775F]   Drosophila melanogaster
FBal0154448 tin[S-255S]   Drosophila melanogaster
FBal0117333 tin[fl.cFa]   Drosophila melanogaster
FBal0189572 tin[Act5C.PH]   Drosophila melanogaster
FBal0086295 tin[unspecified]   Drosophila melanogaster
FBal0154439 tin[S-968F]   Drosophila melanogaster
FBal0154453 tin[F-357F]   Drosophila melanogaster
FBal0035785 tin[294]   Drosophila melanogaster
FBal0154447 tin[S-26F]   Drosophila melanogaster
FBal0154438 tin[US-255F]   Drosophila melanogaster
FBal0154436 tin[dsRNA.si.cKa]   Drosophila melanogaster
FBal0117334 tin[N351Q.cFa]   Drosophila melanogaster
FBal0154446 tin[S-438S]   Drosophila melanogaster
FBal0032861 tin[EC40] loss of function allele, amorphic allele - genetic evidence Drosophila melanogaster
FBal0035783 tin[142Delta32] hypomorphic allele - genetic evidence Drosophila melanogaster
FBal0154450 tin[S-1224F]   Drosophila melanogaster
FBal0035786 tin[305]   Drosophila melanogaster
FBal0035782 tin[142Delta15] hypomorphic allele - genetic evidence Drosophila melanogaster
FBal0035788 tin[45] amorphic allele - genetic evidence Drosophila melanogaster
FBal0154437 tin[dsRNA.cKa]   Drosophila melanogaster
FBal0154443 tin[S-521S]   Drosophila melanogaster
FBal0032860 tin[1]   Drosophila melanogaster

138 Clones

Secondary Identifier DB identifier
RE67956 FBcl0219279
RE01329 FBcl0219291
FI07263 FBcl0481387
RP003629390 FBcl0552880
RP003349417 FBcl0552834
RP003584394 FBcl0552835
RP003039416 FBcl0552836
RP003046068 FBcl0552837
RP003427984 FBcl0552838
RP003643269 FBcl0552839
RP003049529 FBcl0552840
RP003144177 FBcl0552841
RP003191820 FBcl0552842
RP003506152 FBcl0552843
RP003548316 FBcl0552844
RP003476330 FBcl0552845
RP003063873 FBcl0552846
RP003312672 FBcl0552847
RP003119147 FBcl0552848
RP003484404 FBcl0552849
RP003363735 FBcl0552850
RP003585806 FBcl0552851
RP003568058 FBcl0552920
RP003325797 FBcl0552852
RP003054976 FBcl0552853
RP003082173 FBcl0552854
RP003031451 FBcl0552855
RP003549839 FBcl0552856
RP003449684 FBcl0552925
RP003439851 FBcl0552857

3 Exons

DB identifier Symbol
FBgn0004110:1 tin:1
FBgn0004110:2 tin:2
FBgn0004110:3 tin:3

1 Transcripts

DB identifier Gene
FBtr0084086 tin

2 UTRs

Class DB identifier
Organism . Name
FivePrimeUTR FBtr0084086-5-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0084086-3-prime-utr Drosophila melanogaster

Interactions

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Other

0 Pathways

2 Cross References

Identifier
Source . Name

Subject . Primary Identifier
42536 NCBI Entrez Gene identifiers FBgn0004110
67502 BioGRID FBgn0004110

12 Data Sets

Name URL
FlyBase data set for Drosophila melanogaster  
Swiss-Prot data set http://ca.expasy.org/sprot
Drosophila 12 Genomes Consortium homology  
GenomeRNAi data set  
TreeFam data set  
Panther data set  
IntAct interactions data set  
BioGRID interaction data set http://www.thebiogrid.org/downloads.php
GO Annotation from FlyBase  
FlyBase fasta data set for Drosophila melanogaster  
Drosophila Cell Line and Developmental Stage Gene and Exon Scores  
Fly Transcription Factor/microRNA Regulatory Network  

55 Expression Scores


Gene . Primary Identifier

Submission . Title

Cell Line . Name

Developmental Stage . Name
Score
FBgn0004110 Drosophila Cell Line and Developmental Stage Gene and Exon Scores CME L1 53.0
FBgn0004110 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Sg4 63.0
FBgn0004110 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD11 43.0
FBgn0004110 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD20-c2 93.0
FBgn0004110 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD20-c5 156.0
FBgn0004110 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Kc167 81.0
FBgn0004110 Drosophila Cell Line and Developmental Stage Gene and Exon Scores GM2 56.0
FBgn0004110 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S2-DRSC 47.0
FBgn0004110 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S2R+ 138.0
FBgn0004110 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S1 26.0
FBgn0004110 Drosophila Cell Line and Developmental Stage Gene and Exon Scores 1182-4H 23.0
FBgn0004110 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD16-c3 111.0
FBgn0004110 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD32 27.0
FBgn0004110 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD17-c3 89.0
FBgn0004110 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD8 39.0
FBgn0004110 Drosophila Cell Line and Developmental Stage Gene and Exon Scores CME W1 Cl.8+ 108.0
FBgn0004110 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD9 28.0
FBgn0004110 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmBG1-c1 122.0
FBgn0004110 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD21 46.0
FBgn0004110 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD4-c1 8.0
FBgn0004110 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmBG3-c2 28.0
FBgn0004110 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S3 28.0
FBgn0004110 Drosophila Cell Line and Developmental Stage Gene and Exon Scores CME W2 40.0
FBgn0004110 Drosophila Cell Line and Developmental Stage Gene and Exon Scores mbn2 26.0
FBgn0004110 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmBG2-c2 43.0
FBgn0004110 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 0-2 h 64.0
FBgn0004110 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 2-4 h 424.0
FBgn0004110 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 4-6 h 1448.0
FBgn0004110 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 6-8 h 491.0
FBgn0004110 Drosophila Cell Line and Developmental Stage Gene and Exon Scores emb 8-10h 146.0

2 Introns

DB identifier
Organism . Name
intron_FBgn0004110:1_FBgn0004110:2 Drosophila melanogaster
intron_FBgn0004110:2_FBgn0004110:3 Drosophila melanogaster

26 RNAi Results

Screen Gene Phenotype Score Conditions PubMed ID
Lipid storage tin Increased lipid droplet area 2.353507131   19067489
Lipid storage tin Increased lipid droplet area 6.341904585   19067489
Lipid storage tin none 0.286955504   19067489
Lipid storage tin none 0.132948999   19067489
Lipid storage tin none -2.5455984   19067489
Lipid storage tin none 0.51822337   19067489
ERK signaling tin ERK activation reduced weak   17086199
Cell size and cell-cycle regulation (1) tin none sp   16496002
Heart development and function tin Cardiac precursors specification defects np   14684833
Dendrite pattern formation tin none np   16547170
Muscle morphogenesis and function (1) tin Lethal np   20220848
Muscle morphogenesis and function (1) tin none np   20220848
Muscle morphogenesis and function (1) tin Weak flyer np   20220848
Muscle morphogenesis and function (2) tin none np   20220848
Heat nociception (1) tin none -1.17   21074052
Heat nociception (1) tin none -1.17   21074052
Heat nociception (1) tin none 0.55   21074052
Heart development and function (1) tin none 1   20371351
Heart development and function (2) tin Decreased viability 3.84   20371351
Serratia marcescens infection (1) tin none 0.588235294117647   19520911
Notch pathway regulation (4) tin Notum malformation death 8   19363474
Notch pathway regulation (4) tin none 0   19363474
Notch pathway regulation (4) tin Notum malformation death 5   19363474
Adiposity regulation (1) tin none 0.049   20074523
Hippo pathway regulation tin none -1.86   23263283
Glycosylation regulation (1) tin none sp   21203496

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