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Gene : Sra-1 D. melanogaster

DB identifier  ? FBgn0038320 Secondary Identifier  ? CG4931
Name  ? specifically Rac1-associated protein 1 Source  FlyBase
  • synonyms:
  • Sra,
  • Sra1,
  • DSra-1,
  • CYFIP,
  • dSra,
  • CYFIP1/2,
  • sra-1,
  • CG4931,
  • FBgn0038320,
  • PIR121,
  • FBan0004931,
  • PIR121/Sra-1,
  • Sra-1/CYFIP,
  • Sra1/PIR121,
  • specifically, Rac-1 associated protein 1

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24 Alleles

DB identifier Symbol Allele Class Organism
FBal0277089 Sra-1[dsRNA.Scer\UAS.cGa]   Drosophila melanogaster
FBal0181445 Sra-1[d02839]   Drosophila melanogaster
FBal0159733 Sra-1[EY06562]   Drosophila melanogaster
FBal0130591 Sra-1[EP3267]   Drosophila melanogaster
FBal0130590 Sra-1[EP789]   Drosophila melanogaster
FBal0181446 Sra-1[Scer\UAS.T:Myr-Src64B]   Drosophila melanogaster
FBal0181447 Sra-1[DeltaC.Scer\UAS.T:Myr-Src64B]   Drosophila melanogaster
FBal0286705 Sra-1[Scer\UAS.ORF]   Drosophila melanogaster
FBal0286706 Sra-1[Scer\UAS.ORF.T:Ivir\HA1]   Drosophila melanogaster
FBal0152183 Sra-1[35.1] wild-type allele Drosophila melanogaster
FBal0155790 Sra-1[dsRNA.cKa]   Drosophila melanogaster
FBal0152182 Sra-1[5.2]   Drosophila melanogaster
FBal0152179 Sra-1[85.1]   Drosophila melanogaster
FBal0181443 Sra-1[dsRNA.cBa]   Drosophila melanogaster
FBal0152180 Sra-1[8.1]   Drosophila melanogaster
FBal0152178 Sra-1[unspecified]   Drosophila melanogaster
FBal0152181 Sra-1[70.1] wild-type allele Drosophila melanogaster
FBal0181444 Sra-1[dsRNA.Scer\UAS]   Drosophila melanogaster
FBal0159732 Sra-1[Scer\UAS.cSa]   Drosophila melanogaster
FBal0278872 Sra-1[HMS01754]   Drosophila melanogaster
FBal0208621 Sra-1[GD11477]   Drosophila melanogaster
FBal0222284 Sra-1[NP3436]   Drosophila melanogaster
FBal0231269 Sra-1[KK101432]   Drosophila melanogaster
FBal0274445 Sra-1[NIG.4931R]   Drosophila melanogaster

91 Clones

Secondary Identifier DB identifier
EK261922 FBcl0057924
EK200115 FBcl0057928
EK072924 FBcl0057938
EK298907 FBcl0057940
EK269130 FBcl0057946
EK307139 FBcl0057950
EK190805 FBcl0057972
EK217342 FBcl0058764
EK238754 FBcl0058778
EK306416 FBcl0058804
EK188063 FBcl0058810
EK095139 FBcl0058820
EK216064 FBcl0058830
EK117204 FBcl0058834
EK143352 FBcl0058892
EK184320 FBcl0061132
EK155049 FBcl0061632
EK199058 FBcl0061682
EC30440 FBcl0070083
EP15055 FBcl0085841
EP09737 FBcl0086145
EP05716 FBcl0088515
EN12704 FBcl0099289
EN02457 FBcl0101279
GH25824 FBcl0127963
GM06514 FBcl0143467
LD19991 FBcl0159719
LD14526 FBcl0160247
LD47929 FBcl0174728
RE62682 FBcl0226734

9 Exons

DB identifier Symbol
FBgn0038320:1 Sra-1:1
FBgn0038320:2 Sra-1:2
FBgn0038320:3 Sra-1:3
FBgn0038320:4 Sra-1:4
FBgn0038320:5 Sra-1:5
FBgn0038320:6 Sra-1:6
FBgn0038320:7 Sra-1:7
FBgn0038320:8 Sra-1:8
FBgn0038320:9 Sra-1:9

1 Transcripts

DB identifier Gene
FBtr0083085 Sra-1

2 UTRs

Class DB identifier
Organism . Name
FivePrimeUTR FBtr0083085-5-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0083085-3-prime-utr Drosophila melanogaster

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2 Cross References

Identifier
Source . Name

Subject . Primary Identifier
41861 NCBI Entrez Gene identifiers FBgn0038320
66924 BioGRID FBgn0038320

11 Data Sets

Name URL
FlyBase data set for Drosophila melanogaster  
Swiss-Prot data set http://ca.expasy.org/sprot
Drosophila 12 Genomes Consortium homology  
GenomeRNAi data set  
TreeFam data set  
Panther data set  
IntAct interactions data set  
BioGRID interaction data set http://www.thebiogrid.org/downloads.php
GO Annotation from FlyBase  
FlyBase fasta data set for Drosophila melanogaster  
Drosophila Cell Line and Developmental Stage Gene and Exon Scores  

55 Expression Scores


Gene . Primary Identifier

Submission . Title

Cell Line . Name

Developmental Stage . Name
Score
FBgn0038320 Drosophila Cell Line and Developmental Stage Gene and Exon Scores CME L1 2018.0
FBgn0038320 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Sg4 2355.0
FBgn0038320 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD11 1527.0
FBgn0038320 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD20-c2 3339.0
FBgn0038320 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD20-c5 3017.0
FBgn0038320 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Kc167 1588.0
FBgn0038320 Drosophila Cell Line and Developmental Stage Gene and Exon Scores GM2 2084.0
FBgn0038320 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S2-DRSC 2662.0
FBgn0038320 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S2R+ 1209.0
FBgn0038320 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S1 1818.0
FBgn0038320 Drosophila Cell Line and Developmental Stage Gene and Exon Scores 1182-4H 2924.0
FBgn0038320 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD16-c3 1501.0
FBgn0038320 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD32 2310.0
FBgn0038320 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD17-c3 2202.0
FBgn0038320 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD8 2291.0
FBgn0038320 Drosophila Cell Line and Developmental Stage Gene and Exon Scores CME W1 Cl.8+ 1698.0
FBgn0038320 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD9 1635.0
FBgn0038320 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmBG1-c1 2456.0
FBgn0038320 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD21 1531.0
FBgn0038320 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD4-c1 1885.0
FBgn0038320 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmBG3-c2 3217.0
FBgn0038320 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S3 2116.0
FBgn0038320 Drosophila Cell Line and Developmental Stage Gene and Exon Scores CME W2 2463.0
FBgn0038320 Drosophila Cell Line and Developmental Stage Gene and Exon Scores mbn2 2058.0
FBgn0038320 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmBG2-c2 2022.0
FBgn0038320 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 0-2 h 1630.0
FBgn0038320 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 2-4 h 2131.0
FBgn0038320 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 4-6 h 3279.0
FBgn0038320 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 6-8 h 1799.0
FBgn0038320 Drosophila Cell Line and Developmental Stage Gene and Exon Scores emb 8-10h 1592.0

8 Introns

DB identifier
Organism . Name
intron_FBgn0038320:1_FBgn0038320:2 Drosophila melanogaster
intron_FBgn0038320:2_FBgn0038320:3 Drosophila melanogaster
intron_FBgn0038320:3_FBgn0038320:4 Drosophila melanogaster
intron_FBgn0038320:4_FBgn0038320:5 Drosophila melanogaster
intron_FBgn0038320:5_FBgn0038320:6 Drosophila melanogaster
intron_FBgn0038320:6_FBgn0038320:7 Drosophila melanogaster
intron_FBgn0038320:7_FBgn0038320:8 Drosophila melanogaster
intron_FBgn0038320:8_FBgn0038320:9 Drosophila melanogaster

26 RNAi Results

Screen Gene Phenotype Score Conditions PubMed ID
Lipid storage Sra-1 none 1.944771957   19067489
Lipid storage Sra-1 none -0.100187856   19067489
Neural outgrowth Sra-1 Cell cluster defect np   18604272
Actin morphology Sra-1 Perturbed formation of actin-based protrusions np   14588242
Actin morphology Sra-1 Stellate morphology np   12975351
Intracellular Listeria monocytogenes infection Sra-1 Decreased GFP protein expression moderate   16020693
Mycobacterial infection (1) - M. fortuitum infection Sra-1 Decreased M. fortuitum intracellular infection 3 measurement after 5 days 16020694
Mycobacterial infection (2) - E. coli phagocytosis Sra-1 Decreased E. coli phagocytosis np   16020694
Cell size and cell-cycle regulation (1) Sra-1 none sp   16496002
Candida albicans phagocytosis (1) Sra-1 Decreased Candida albicans phagocytosis np   16336044
Candida albicans phagocytosis (2) Sra-1 none 56   16336044
Candida albicans phagocytosis (3) Sra-1 Decreased latex beads phagocytosis 34   16336044
C. trachomatis infection Sra-1 C. trachomatis infection down np   18369471
Muscle morphogenesis and function (1) Sra-1 Weak flyer np   20220848
Muscle morphogenesis and function (1) Sra-1 Lethal np   20220848
Heat nociception (1) Sra-1 none -1.17   21074052
Heat nociception (1) Sra-1 none -1.17   21074052
Heart development and function (1) Sra-1 none 1   20371351
Serratia marcescens infection (1) Sra-1 none 0.222222222222222   19520911
Notch pathway regulation (4) Sra-1 none 0   19363474
Notch pathway regulation (4) Sra-1 Planar polarity defects, notum malformation migration sp   19363474
PGN-induced dJNK phosphorylation Sra-1 Increased P-JNK protein expression with PGN 2.54 15 min PGN induction 19893628
Adiposity regulation (1) Sra-1 none -0.16   20074523
S2 cell spreading Sra-1 Stellate morphology on Con A surface sp   21041442
Hippo pathway regulation Sra-1 none -0.84   23263283
Glycosylation regulation (1) Sra-1 none sp   21203496

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