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Gene : betaTub56D D. melanogaster

DB identifier  ? FBgn0003887 Secondary Identifier  ? CG9277
Name  ? beta-Tubulin at 56D Source  FlyBase
  • synonyms:
  • Tubulin beta-1 chain,
  • beta-Tub,
  • B1t,
  • beta-tubulin-56D,
  • T,
  • Tub,
  • Tubulin,
  • CG9277,
  • DTB2,
  • betaTub,
  • A1ZBL0_DROME,
  • beta,
  • FBan0009277,
  • betaTub1,
  • BETA 56D,
  • Beta tubulin,
  • beta1-tub,
  • betatubulin,
  • 1t,
  • FBgn0003887,
  • betaTub56D,
  • beta-tubulin 56D,
  • Tubulin beta1-chain,
  • beta[[1]] tubulin,
  • beta[[1]]-tubulin,
  • beta1-Tubulin,
  • beta-1-tubulin,
  • beta-Tubulin,
  • TBB1_DROME,
  • beta1t,
  • b-tubulin56D,
  • beta-Tubulin at 56 D,
  • beta1 tubulin,
  • beta-Tubulin at 56D,
  • beta1Tub,
  • beta-Tub56D,
  • beta-tubulin56D,
  • beta1,
  • beta-1 tubulin,
  • Dmbeta1,
  • betatub(56D),
  • beta56D

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24 Alleles

DB identifier Symbol Allele Class Organism
FBal0211764 betaTub56D[CC02069]   Drosophila melanogaster
FBal0188368 betaTub56D[e04244]   Drosophila melanogaster
FBal0188369 betaTub56D[e04006]   Drosophila melanogaster
FBal0188370 betaTub56D[d07340]   Drosophila melanogaster
FBal0148518 betaTub56D[127]   Drosophila melanogaster
FBal0131824 betaTub56D[EP2640]   Drosophila melanogaster
FBal0259730 betaTub56D[KK108806]   Drosophila melanogaster
FBal0286544 betaTub56D[Scer\UAS.ORF]   Drosophila melanogaster
FBal0286545 betaTub56D[Scer\UAS.ORF.T:Ivir\HA1]   Drosophila melanogaster
FBal0278218 betaTub56D[Scer\UAS.P\T.T:Avic\GFP]   Drosophila melanogaster
FBal0277492 betaTub56D[Ubi-p63E.T:Avic\GFP]   Drosophila melanogaster
FBal0192652 betaTub56D[EY21785]   Drosophila melanogaster
FBal0059636 betaTub56D[betaTub85D.PK]   Drosophila melanogaster
FBal0125511 betaTub56D[betaTub85D.int]   Drosophila melanogaster
FBal0125512 betaTub56D[betaTub85D.PR]   Drosophila melanogaster
FBal0125513 betaTub56D[beta1-beta2.ii]   Drosophila melanogaster
FBal0262846 betaTub56D[GL00380]   Drosophila melanogaster
FBal0286242 betaTub56D[YC0063]   Drosophila melanogaster
FBal0268994 betaTub56D[T:Avic\GFP]   Drosophila melanogaster
FBal0198562 betaTub56D[GD14171]   Drosophila melanogaster
FBal0220236 betaTub56D[GSG5793]   Drosophila melanogaster
FBal0223610 betaTub56D[CB-5701-3]   Drosophila melanogaster
FBal0223611 betaTub56D[e00567]   Drosophila melanogaster
FBal0223612 betaTub56D[SH0137]   Drosophila melanogaster

751 Clones

Secondary Identifier DB identifier
ESG0112d.B21_E06 FBcl0001717
ESG0110a.E21_E05 FBcl0003363
UUGC0905 FBcl0005023
UUGC0468 FBcl0005979
ESG017b.E21_C09 FBcl0007253
AT26230 FBcl0037563
ESG014c.E21_F04 FBcl0012189
EK250501 FBcl0027750
EK276412 FBcl0027758
EK064816 FBcl0027786
EK004836 FBcl0027792
EK039202 FBcl0027802
EK265226 FBcl0027828
EK012536 FBcl0027866
EC00373 FBcl0071393
EP14856 FBcl0087113
EN13833 FBcl0100397
GH27941 FBcl0136477
GH12877 FBcl0136483
GH15303 FBcl0136487
GH27942 FBcl0136489
GM01137 FBcl0143101
GM03926 FBcl0143102
GM06704 FBcl0143103
GM06494 FBcl0143104
GM03813 FBcl0143105
GM02624 FBcl0143108
GM06189 FBcl0143110
GM02374 FBcl0143111
GM05629 FBcl0143112

3 Exons

DB identifier Symbol
FBgn0003887:3 betaTub56D:3
FBgn0003887:1 betaTub56D:1
FBgn0003887:2 betaTub56D:2

2 Transcripts

DB identifier Gene
FBtr0086536 betaTub56D
FBtr0086537 betaTub56D

4 UTRs

Class DB identifier
Organism . Name
FivePrimeUTR FBtr0086536-5-prime-utr Drosophila melanogaster
FivePrimeUTR FBtr0086537-5-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0086536-3-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0086537-3-prime-utr Drosophila melanogaster

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2 Cross References

Identifier
Source . Name

Subject . Primary Identifier
37238 NCBI Entrez Gene identifiers FBgn0003887
62900 BioGRID FBgn0003887

11 Data Sets

Name URL
FlyBase data set for Drosophila melanogaster  
Swiss-Prot data set http://ca.expasy.org/sprot
Drosophila 12 Genomes Consortium homology  
GenomeRNAi data set  
TreeFam data set  
Panther data set  
IntAct interactions data set  
BioGRID interaction data set http://www.thebiogrid.org/downloads.php
GO Annotation from FlyBase  
FlyBase fasta data set for Drosophila melanogaster  
Drosophila Cell Line and Developmental Stage Gene and Exon Scores  

55 Expression Scores


Gene . Primary Identifier

Submission . Title

Cell Line . Name

Developmental Stage . Name
Score
FBgn0003887 Drosophila Cell Line and Developmental Stage Gene and Exon Scores CME L1 10845.0
FBgn0003887 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Sg4 10459.0
FBgn0003887 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD11 12451.0
FBgn0003887 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD20-c2 14810.0
FBgn0003887 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD20-c5 12370.0
FBgn0003887 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Kc167 11220.0
FBgn0003887 Drosophila Cell Line and Developmental Stage Gene and Exon Scores GM2 7006.0
FBgn0003887 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S2-DRSC 7740.0
FBgn0003887 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S2R+ 8700.0
FBgn0003887 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S1 8866.0
FBgn0003887 Drosophila Cell Line and Developmental Stage Gene and Exon Scores 1182-4H 10046.0
FBgn0003887 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD16-c3 10525.0
FBgn0003887 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD32 11174.0
FBgn0003887 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD17-c3 15605.0
FBgn0003887 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD8 15333.0
FBgn0003887 Drosophila Cell Line and Developmental Stage Gene and Exon Scores CME W1 Cl.8+ 12112.0
FBgn0003887 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD9 11061.0
FBgn0003887 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmBG1-c1 9936.0
FBgn0003887 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD21 12993.0
FBgn0003887 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD4-c1 11916.0
FBgn0003887 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmBG3-c2 12525.0
FBgn0003887 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S3 10355.0
FBgn0003887 Drosophila Cell Line and Developmental Stage Gene and Exon Scores CME W2 7591.0
FBgn0003887 Drosophila Cell Line and Developmental Stage Gene and Exon Scores mbn2 6886.0
FBgn0003887 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmBG2-c2 5875.0
FBgn0003887 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 0-2 h 13281.0
FBgn0003887 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 2-4 h 12557.0
FBgn0003887 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 4-6 h 12742.0
FBgn0003887 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 6-8 h 10544.0
FBgn0003887 Drosophila Cell Line and Developmental Stage Gene and Exon Scores emb 8-10h 11363.0

2 Introns

DB identifier
Organism . Name
intron_FBgn0003887:3_FBgn0003887:1 Drosophila melanogaster
intron_FBgn0003887:2_FBgn0003887:1 Drosophila melanogaster

28 RNAi Results

Screen Gene Phenotype Score Conditions PubMed ID
Cell size regulation betaTub56D none -2.91   19216764
Lipid storage betaTub56D none -0.010410696   19067489
Lipid storage betaTub56D none -0.220546744   19067489
ERK signaling betaTub56D ERK activation reduced weak   17086199
Intracellular Listeria monocytogenes infection betaTub56D Decreased GFP protein expression weak   16020693
Constitutive protein secretion and Golgi organization (1) betaTub56D Decreased horseradish peroxidase protein expression sp   16452979
Cell size and cell-cycle regulation (1) betaTub56D Decreased G1 cell size, decreased viability, increased cytokinesis sp   16496002
Cell size and cell-cycle regulation (2) betaTub56D none 1.214   16496002
Cell size and cell-cycle regulation (3) betaTub56D Decreased cell number 246   16496002
Cell size and cell-cycle regulation (4) betaTub56D none below threshold   16496002
Mitosis betaTub56D Dim microtubules np   17412918
Microtubule assembly and organization betaTub56D none np   18463163
Muscle morphogenesis and function (1) betaTub56D Lethal np   20220848
Heat nociception (1) betaTub56D Lethal -1.17   21074052
Heart development and function (1) betaTub56D none 1   20371351
Serratia marcescens infection (1) betaTub56D none -0.311475409836065   19520911
Notch pathway regulation (4) betaTub56D Completely lethal (pupal) sp   19363474
Adiposity regulation (1) betaTub56D none -0.061   20074523
RTK-Ras-ERK pathway regulation (1) betaTub56D Increased ERK phosphorylation after EGF stimulation 2.27 0 minutes EGF stimulation 22028469
RTK-Ras-ERK pathway regulation (1) betaTub56D Decreased ERK phosphorylation after EGF stimulation -1.65 10 minutes EGF stimulation 22028469
RTK-Ras-ERK pathway regulation (2) betaTub56D none -0.51 10 minutes sSpitz stimulation 22028469
RTK-Ras-ERK pathway regulation (2) betaTub56D none -1.24 30 minutes sSpitz stimulation 22028469
Wnt proteins secretion betaTub56D none 0.7   22094269
Hippo pathway regulation betaTub56D none 1.64   23263283
Muscle development and maintenance betaTub56D Pupal lethal sp  
Muscle maintenance betaTub56D none sp  
Glycosylation regulation (4) betaTub56D none sp   21203496
Huntingtin (Htt) aggregates formation betaTub56D Decreased formation of mutant Huntingtin (Httex1-Qn) protein aggregates np   20100940

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