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Gene : RpL8 D. melanogaster

DB identifier  ? FBgn0261602 Secondary Identifier  ? CG1263
Name  ? Ribosomal protein L8 Source  FlyBase
  • synonyms:
  • FBgn0261602,
  • FBgn0024939,
  • FBgn0002611,
  • FBan0001263,
  • Minute(3)62F,
  • RPL8,
  • FBgn0069397,
  • CG1263,
  • FBgn0027679,
  • anon-EST:Posey5,
  • FBgn0035352,
  • M(3)LS2,
  • M(3)62F,
  • Rp L8,
  • L8

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8 Alleles

DB identifier Symbol Allele Class Organism
FBal0284512 RpL8[Scer\UAS.T:Disc\RFP]   Drosophila melanogaster
FBal0280383 RpL8[Scer\UAS.cXa]   Drosophila melanogaster
FBal0280384 RpL8[dsRNA.Scer\UAS]   Drosophila melanogaster
FBal0287204 RpL8[Scer\UAS.ORF]   Drosophila melanogaster
FBal0287205 RpL8[Scer\UAS.ORF.T:Ivir\HA1]   Drosophila melanogaster
FBal0208362 RpL8[GD7780]   Drosophila melanogaster
FBal0219303 RpL8[DG02501]   Drosophila melanogaster
FBal0235270 RpL8[KK107946]   Drosophila melanogaster

851 Clones

Secondary Identifier DB identifier
LD20981 FBcl0304241
FGH127A12 FBcl0388530
ESG0116b.B21_A08 FBcl0002989
bs54c01 FBcl0048597
EK165461 FBcl0092350
EK054345 FBcl0092356
EK111764 FBcl0092374
EK185740 FBcl0092468
EN15315 FBcl0092599
EN07650 FBcl0092605
EN13403 FBcl0092623
EN14550 FBcl0092691
GH26707 FBcl0121269
GH10749 FBcl0132337
GH11466 FBcl0132385
GH07158 FBcl0132387
GH03092 FBcl0132389
GH26084 FBcl0132393
GH28794 FBcl0132409
GH25541 FBcl0132417
GH20127 FBcl0132419
GH27831 FBcl0132423
GH21637 FBcl0132425
GH20142 FBcl0132427
GH25150 FBcl0132431
GH12761 FBcl0132435
GH18817 FBcl0132439
GH18436 FBcl0132441
GH19681 FBcl0132443
GH27491 FBcl0132445

4 Exons

DB identifier Symbol
FBgn0261602:1 RpL8:1
FBgn0261602:3 RpL8:3
FBgn0261602:4 RpL8:4
FBgn0261602:2 RpL8:2

2 Transcripts

DB identifier Gene
FBtr0072925 RpL8
FBtr0072924 RpL8

4 UTRs

Class DB identifier
Organism . Name
FivePrimeUTR FBtr0072924-5-prime-utr Drosophila melanogaster
FivePrimeUTR FBtr0072925-5-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0072924-3-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0072925-3-prime-utr Drosophila melanogaster

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49 Pathways

2 Cross References

Identifier
Source . Name

Subject . Primary Identifier
44251 NCBI Entrez Gene identifiers FBgn0261602
68919 BioGRID FBgn0261602

10 Data Sets

Name URL
FlyBase data set for Drosophila melanogaster  
Swiss-Prot data set http://ca.expasy.org/sprot
Drosophila 12 Genomes Consortium homology  
GenomeRNAi data set  
TreeFam data set  
Panther data set  
IntAct interactions data set  
BioGRID interaction data set http://www.thebiogrid.org/downloads.php
GO Annotation from FlyBase  
FlyBase fasta data set for Drosophila melanogaster  

0 Expression Scores

4 Introns

DB identifier
Organism . Name
intron_FBgn0261602:1_FBgn0261602:3 Drosophila melanogaster
intron_FBgn0261602:3_FBgn0261602:4 Drosophila melanogaster
intron_FBgn0261602:1_FBgn0261602:2 Drosophila melanogaster
intron_FBgn0261602:2_FBgn0261602:4 Drosophila melanogaster

41 RNAi Results

Screen Gene Phenotype Score Conditions PubMed ID
Lipid storage RpL8 Increased lipid droplet area 2.337472503   19067489
Lipid storage RpL8 Increased lipid droplet area 2.019849313   19067489
Lipid storage RpL8 none 1.325405774   19067489
Lipid storage RpL8 none 1.948651145   19067489
Drosophila C virus infection RpL8 Drosophila C virus replication down np   17040126
Cytokinesis regulation RpL8 Binucleate cells weak   15547975
Intracellular Listeria monocytogenes infection RpL8 Increased GFP protein expression strong   16020693
Drosophila C virus infection RpL8 Drosophila C virus infection reduced np   15713840
Hedgehog signaling RpL8 Decreased Hedgehog reporter activity -2.51   16311596
Hedgehog signaling RpL8 Decreased Hedgehog reporter activity -2.68   16311596
Constitutive protein secretion and Golgi organization (1) RpL8 Decreased horseradish peroxidase protein expression sp   16452979
Constitutive protein secretion and Golgi organization (1) RpL8 Decreased horseradish peroxidase protein expression sp   16452979
Cell size and cell-cycle regulation (1) RpL8 Increased G1 DNA content, decreased G2 DNA content, decreased G1 cell size, decreased viability sp   16496002
Cell size and cell-cycle regulation (1) RpL8 none sp   16496002
Cell size and cell-cycle regulation (1) RpL8 none sp   16496002
Cell size and cell-cycle regulation (1) RpL8 Increased G1 DNA content, decreased viability, decreased cytokinesis sp   16496002
Cell size and cell-cycle regulation (2) RpL8 Decreased viability 0.697   16496002
Cell size and cell-cycle regulation (2) RpL8 Decreased viability 0.751   16496002
Cell size and cell-cycle regulation (3) RpL8 none 419   16496002
Cell size and cell-cycle regulation (3) RpL8 none 443   16496002
Lipid storage RpL8 More dispersed droplets strong (but ribosomal)   18408709
Muscle morphogenesis and function (1) RpL8 Lethal np   20220848
Muscle morphogenesis and function (2) RpL8 Wing posture / locomotion / ability to fly defect or lethal / semi-lethal np   20220848
Muscle morphogenesis and function (3) RpL8 Spotty (discontinuous) Z-line np   20220848
Heat nociception (1) RpL8 Lethal -1.17   21074052
Heart development and function (1) RpL8 Adult lethal 0.5   20371351
Serratia marcescens infection (1) RpL8 none 0.267605633802816   19520911
Notch pathway regulation (4) RpL8 Completely lethal (pupal) sp   19363474
Hh pathway regulation RpL8 Downregulation of Hh pathway -0.618078473550773   17903264
Hh pathway regulation RpL8 Downregulation of Hh pathway -0.556547226933904   17903264

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