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Gene : Spc105R D. melanogaster

DB identifier  ? FBgn0037025 Secondary Identifier  ? CG11451
Name  ? Spc105-related Source  FlyBase
  • synonyms:
  • dmKNL-1,
  • FBgn0037025,
  • dmSpc105R,
  • FBan0011451,
  • DmSpc105,
  • CG11451,
  • Spc105

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20 Alleles

DB identifier Symbol Allele Class Organism
FBal0267954 Spc105R[HM04030]   Drosophila melanogaster
FBal0243491 Spc105R[1] amorphic allele - genetic evidence Drosophila melanogaster
FBal0243492 Spc105R[P01511LE] amorphic allele - genetic evidence Drosophila melanogaster
FBal0243493 Spc105R[+tg]   Drosophila melanogaster
FBal0243494 Spc105R[gC]   Drosophila melanogaster
FBal0243495 Spc105R[N.T:Avic\GFP-EGFP]   Drosophila melanogaster
FBal0243496 Spc105R[C.T:Avic\GFP-EGFP]   Drosophila melanogaster
FBal0243497 Spc105R[N.T:Avic\GFP-EGFP.C.T:Disc\RFP-mRFP]   Drosophila melanogaster
FBal0243498 Spc105R[wr1]   Drosophila melanogaster
FBal0243499 Spc105R[FL.Scer\UAS.T:Avic\GFP-EGFP]   Drosophila melanogaster
FBal0243500 Spc105R[N.Scer\UAS.T:Avic\GFP-EGFP]   Drosophila melanogaster
FBal0243501 Spc105R[M.Scer\UAS.T:Avic\GFP-EGFP]   Drosophila melanogaster
FBal0243502 Spc105R[C.Scer\UAS.T:Avic\GFP-EGFP]   Drosophila melanogaster
FBal0276745 Spc105R[Scer\UAS.P\T.C.T:Avic\GFP-EGFP]   Drosophila melanogaster
FBal0259420 Spc105R[KK106153]   Drosophila melanogaster
FBal0266455 Spc105R[HMS01548]   Drosophila melanogaster
FBal0262858 Spc105R[GL00392]   Drosophila melanogaster
FBal0278870 Spc105R[HMS01752]   Drosophila melanogaster
FBal0199438 Spc105R[GD7306]   Drosophila melanogaster
FBal0270874 Spc105R[NIG.11451R]   Drosophila melanogaster

37 Clones

Secondary Identifier DB identifier
EC26112 FBcl0070241
EC25412 FBcl0070243
EP06504 FBcl0086099
EP07804 FBcl0086107
GH15349 FBcl0124557
EK193452 FBcl0128986
EK062650 FBcl0134858
LD15040 FBcl0158701
LD41231 FBcl0173307
LP22061 FBcl0187787
LP21544 FBcl0188777
LP17452 FBcl0188796
DMG3-chr3L.7637.pred.a FBcl0362427
FGM104G10 FBcl0389354
214471.3 FBcl0454546
CK01.81A.E4 FBcl0454591
IP22012 FBcl0474996
RP004422058 FBcl0695511
RP004160023 FBcl0695512
RP004210046 FBcl0695513
RP004244241 FBcl0695514
RP004370553 FBcl0695515
RP004447963 FBcl0695516
RP004257045 FBcl0695517
RP004203052 FBcl0695518
RP004239707 FBcl0695519
RP004244619 FBcl0695520
RP004388703 FBcl0695521
RP004269516 FBcl0695522
RP004338273 FBcl0695523

8 Exons

DB identifier Symbol
FBgn0037025:1 Spc105R:1
FBgn0037025:3 Spc105R:3
FBgn0037025:4 Spc105R:4
FBgn0037025:5 Spc105R:5
FBgn0037025:6 Spc105R:6
FBgn0037025:8 Spc105R:8
FBgn0037025:2 Spc105R:2
FBgn0037025:7 Spc105R:7

2 Transcripts

DB identifier Gene
FBtr0321284 Spc105R
FBtr0078255 Spc105R

4 UTRs

Class DB identifier
Organism . Name
FivePrimeUTR FBtr0078255-5-prime-utr Drosophila melanogaster
FivePrimeUTR FBtr0321284-5-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0078255-3-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0321284-3-prime-utr Drosophila melanogaster

Interactions

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Other

0 Pathways

2 Cross References

Identifier
Source . Name

Subject . Primary Identifier
40300 NCBI Entrez Gene identifiers FBgn0037025
65557 BioGRID FBgn0037025

9 Data Sets

Name URL
FlyBase data set for Drosophila melanogaster  
TrEMBL data set http://www.ebi.ac.uk/trembl/
Drosophila 12 Genomes Consortium homology  
GenomeRNAi data set  
IntAct interactions data set  
BioGRID interaction data set http://www.thebiogrid.org/downloads.php
GO Annotation from FlyBase  
FlyBase fasta data set for Drosophila melanogaster  
Drosophila Cell Line and Developmental Stage Gene and Exon Scores  

55 Expression Scores


Gene . Primary Identifier

Submission . Title

Cell Line . Name

Developmental Stage . Name
Score
FBgn0037025 Drosophila Cell Line and Developmental Stage Gene and Exon Scores CME L1 461.0
FBgn0037025 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Sg4 735.0
FBgn0037025 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD11 495.0
FBgn0037025 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD20-c2 353.0
FBgn0037025 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD20-c5 450.0
FBgn0037025 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Kc167 282.0
FBgn0037025 Drosophila Cell Line and Developmental Stage Gene and Exon Scores GM2 582.0
FBgn0037025 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S2-DRSC 296.0
FBgn0037025 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S2R+ 655.0
FBgn0037025 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S1 492.0
FBgn0037025 Drosophila Cell Line and Developmental Stage Gene and Exon Scores 1182-4H 450.0
FBgn0037025 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD16-c3 700.0
FBgn0037025 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD32 421.0
FBgn0037025 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD17-c3 370.0
FBgn0037025 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD8 293.0
FBgn0037025 Drosophila Cell Line and Developmental Stage Gene and Exon Scores CME W1 Cl.8+ 321.0
FBgn0037025 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD9 584.0
FBgn0037025 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmBG1-c1 567.0
FBgn0037025 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD21 284.0
FBgn0037025 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD4-c1 421.0
FBgn0037025 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmBG3-c2 354.0
FBgn0037025 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S3 425.0
FBgn0037025 Drosophila Cell Line and Developmental Stage Gene and Exon Scores CME W2 458.0
FBgn0037025 Drosophila Cell Line and Developmental Stage Gene and Exon Scores mbn2 440.0
FBgn0037025 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmBG2-c2 443.0
FBgn0037025 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 0-2 h 1036.0
FBgn0037025 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 2-4 h 304.0
FBgn0037025 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 4-6 h 832.0
FBgn0037025 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 6-8 h 743.0
FBgn0037025 Drosophila Cell Line and Developmental Stage Gene and Exon Scores emb 8-10h 596.0

7 Introns

DB identifier
Organism . Name
intron_FBgn0037025:2_FBgn0037025:4 Drosophila melanogaster
intron_FBgn0037025:4_FBgn0037025:5 Drosophila melanogaster
intron_FBgn0037025:5_FBgn0037025:6 Drosophila melanogaster
intron_FBgn0037025:6_FBgn0037025:7 Drosophila melanogaster
intron_FBgn0037025:1_FBgn0037025:3 Drosophila melanogaster
intron_FBgn0037025:3_FBgn0037025:4 Drosophila melanogaster
intron_FBgn0037025:6_FBgn0037025:8 Drosophila melanogaster

28 RNAi Results

Screen Gene Phenotype Score Conditions PubMed ID
Lipid storage Spc105R none 0.706641336   19067489
Lipid storage Spc105R none 0.687336797   19067489
ERK signaling Spc105R ERK activation reduced strong   17086199
Cytokinesis regulation Spc105R Binucleate cells weak   15547975
Intracellular Listeria monocytogenes infection Spc105R Decreased GFP protein expression moderate   16020693
Constitutive protein secretion and Golgi organization (1) Spc105R Decreased horseradish peroxidase protein expression sp   16452979
Cell size and cell-cycle regulation (1) Spc105R none sp   16496002
Mitosis Spc105R Chromosome misalignment np   17412918
Muscle morphogenesis and function (1) Spc105R none np   20220848
Muscle morphogenesis and function (1) Spc105R Lethal np   20220848
Muscle morphogenesis and function (1) Spc105R Lethal np   20220848
Heat nociception (1) Spc105R none -0.76   21074052
Heat nociception (1) Spc105R none -0.07   21074052
Heat nociception (1) Spc105R Developmentally lethal 0.92   21074052
Serratia marcescens infection (1) Spc105R none 1.33695652173913   19520911
Notch pathway regulation (4) Spc105R Completely lethal (pupal) sp   19363474
Notch pathway regulation (4) Spc105R none 0   19363474
Notch pathway regulation (4) Spc105R Completely lethal (pupal) sp   19363474
Self-renewal and differentiation in neural stem cells Spc105R GFP aggregates number, GFP aggregates size, neuroblast larger cell size, neuroblast less large cells, ganglion mother cell shorter lineages, neuroblast loss, neuroblast loss with larger neuroblast cell size, neuroblast underproliferation, lethal sp   21549331
Adiposity regulation (1) Spc105R none -0.041   20074523
Blood cell homeostasis regulation (1) Spc105R none np   20540764
Blood cell homeostasis regulation (2) Spc105R none np   20540764
RTK-Ras-ERK pathway regulation (1) Spc105R none -0.33 0 minutes EGF stimulation 22028469
RTK-Ras-ERK pathway regulation (1) Spc105R Decreased ERK phosphorylation after EGF stimulation -3.1 10 minutes EGF stimulation 22028469
RTK-Ras-ERK pathway regulation (2) Spc105R none 0.21 30 minutes sSpitz stimulation 22028469
RTK-Ras-ERK pathway regulation (2) Spc105R none 0.83 10 minutes sSpitz stimulation 22028469
Hippo pathway regulation Spc105R none 2.06   23263283
Glycosylation regulation (1) Spc105R none sp   21203496

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