Genomics
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33 Alleles
106 Clones
6 Exons
| DB identifier | Symbol |
|---|---|
| FBgn0023169:1 | SNF1A:1 |
| FBgn0023169:3 | SNF1A:3 |
| FBgn0023169:5 | SNF1A:5 |
| FBgn0023169:2 | SNF1A:2 |
| FBgn0023169:6 | SNF1A:6 |
| FBgn0023169:4 | SNF1A:4 |
6 UTRs
| Class | DB identifier |
Organism . Name |
|---|---|---|
| FivePrimeUTR | FBtr0070216-5-prime-utr | Drosophila melanogaster |
| FivePrimeUTR | FBtr0070217-5-prime-utr | Drosophila melanogaster |
| FivePrimeUTR | FBtr0070218-5-prime-utr | Drosophila melanogaster |
| ThreePrimeUTR | FBtr0070216-3-prime-utr | Drosophila melanogaster |
| ThreePrimeUTR | FBtr0070217-3-prime-utr | Drosophila melanogaster |
| ThreePrimeUTR | FBtr0070218-3-prime-utr | Drosophila melanogaster |
Other
27 Pathways
- mTORC1-mediated signalling,
- Fatty acid, triacylglycerol, and ketone body metabolism,
- AMPK inhibits chREBP transcriptional activation activity,
- mTOR signalling,
- Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R),
- Insulin receptor mediated signaling,
- IRS activation,
- PKB-mediated events,
- Signaling Pathways,
- IRS-mediated signalling,
- IRS-related events triggered by IGF1R,
- Metabolism,
- Energy dependent regulation of mTOR by LKB1-AMPK,
- Regulation of AMPK activity via LKB1,
- IGF1R signaling cascade,
- TOR signaling pathway,
- Metabolism of lipids and lipoproteins,
- DINR-mediated activation,
- Insulin receptor recycling,
- Regulation of Rheb GTPase activity by AMPK,
- Import of palmitoyl-CoA into the mitochondrial matrix,
- IRS-related events,
- Integration of energy metabolism,
- Release of eIF4E,
- Insulin signaling pathway,
- Insulin receptor signalling cascade,
- PI3K Cascade
2 Cross References
| Identifier |
Source . Name |
Subject . Primary Identifier |
|---|---|---|
| 43904 | NCBI Entrez Gene identifiers | FBgn0023169 |
| 68705 | BioGRID | FBgn0023169 |
11 Data Sets
| Name | URL |
|---|---|
| FlyBase data set for Drosophila melanogaster | |
| TrEMBL data set | http://www.ebi.ac.uk/trembl/ |
| Drosophila 12 Genomes Consortium homology | |
| GenomeRNAi data set | |
| TreeFam data set | |
| Panther data set | |
| IntAct interactions data set | |
| BioGRID interaction data set | http://www.thebiogrid.org/downloads.php |
| GO Annotation from FlyBase | |
| FlyBase fasta data set for Drosophila melanogaster | |
| Drosophila Cell Line and Developmental Stage Gene and Exon Scores |
55 Expression Scores
5 Introns
39 RNAi Results
| Screen | Gene | Phenotype | Score | Conditions | PubMed ID |
|---|---|---|---|---|---|
| Lipid storage | SNF1A | none | 0.48003646 | 19067489 | |
| Cell cycle regulation (1) | SNF1A | Increased S DNA content, increased G2/M DNA content, all mitotic defects, centrosome defects | sp | 15616552 | |
| Cell cycle regulation (2) | SNF1A | Increased S DNA content or increased number of aneuploid cells, increased G2 DNA content | np | 15616552 | |
| Cell size and cell-cycle regulation (1) | SNF1A | none | sp | 16496002 | |
| Cell size and cell-cycle regulation (1) | SNF1A | none | sp | 16496002 | |
| Cell size and cell-cycle regulation (1) | SNF1A | none | sp | 16496002 | |
| Cell size and cell-cycle regulation (2) | SNF1A | none | 1.156 | 16496002 | |
| Cell size and cell-cycle regulation (3) | SNF1A | none | 459 | 16496002 | |
| Cell size and cell-cycle regulation (4) | SNF1A | Increased number of mitotic cells | 1.1 | 16496002 | |
| Candida albicans phagocytosis (1) | SNF1A | Decreased Candida albicans phagocytosis | np | 16336044 | |
| Candida albicans phagocytosis (2) | SNF1A | none | 46 | 16336044 | |
| Candida albicans phagocytosis (3) | SNF1A | Decreased latex beads phagocytosis | 34 | 16336044 | |
| DFoxO signaling | SNF1A | Decreased dFoxO reporter activity | 0.002 | 18815370 | |
| Combinatorial effect with methyl methanesulphonate (1) | SNF1A | none | sp | 19543366 | |
| Combinatorial effect with methyl methanesulphonate (2) | SNF1A | none | sp | 19543366 | |
| Muscle morphogenesis and function (1) | SNF1A | Lethal | np | 20220848 | |
| Muscle morphogenesis and function (1) | SNF1A | Lethal | np | 20220848 | |
| Muscle morphogenesis and function (2) | SNF1A | Wing posture / locomotion / ability to fly defect or lethal / semi-lethal | np | 20220848 | |
| Heat nociception (1) | SNF1A | none | 0.83 | 21074052 | |
| Heart development and function (1) | SNF1A | none | 1 | 20371351 | |
| Serratia marcescens infection (1) | SNF1A | none | -0.36734693877551 | 19520911 | |
| Notch pathway regulation (4) | SNF1A | none | 0 | 19363474 | |
| PGN-induced dJNK phosphorylation | SNF1A | Increased P-JNK protein expression with PGN | 3.24 | 60 min PGN induction | 19893628 |
| Akt-TOR pathway negative feedback regulation | SNF1A | Decreased dAkt phosphorylation after insulin stimulation | -2.7 | 10 min insulin stimulation | 20585550 |
| Adiposity regulation (1) | SNF1A | none | -0.152 | 20074523 | |
| Blood cell homeostasis regulation (1) | SNF1A | none | np | 20540764 | |
| Blood cell homeostasis regulation (2) | SNF1A | Increased melanotic mass formation | np | 20540764 | |
| Blood cell homeostasis regulation (3) | SNF1A | none | 0 | 20540764 | |
| Blood cell homeostasis regulation (4) | SNF1A | none | 0 | 20540764 | |
| Blood cell homeostasis regulation (5) | SNF1A | none | 0 | 20540764 |
