Genomics
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31 Alleles
149 Clones
11 Exons
| DB identifier | Symbol |
|---|---|
| FBgn0015806:11 | S6k:11 |
| FBgn0015806:10 | S6k:10 |
| FBgn0015806:9 | S6k:9 |
| FBgn0015806:8 | S6k:8 |
| FBgn0015806:7 | S6k:7 |
| FBgn0015806:6 | S6k:6 |
| FBgn0015806:5 | S6k:5 |
| FBgn0015806:4 | S6k:4 |
| FBgn0015806:3 | S6k:3 |
| FBgn0015806:2 | S6k:2 |
| FBgn0015806:1 | S6k:1 |
4 UTRs
| Class | DB identifier |
Organism . Name |
|---|---|---|
| FivePrimeUTR | FBtr0077114-5-prime-utr | Drosophila melanogaster |
| FivePrimeUTR | FBtr0333264-5-prime-utr | Drosophila melanogaster |
| ThreePrimeUTR | FBtr0077114-3-prime-utr | Drosophila melanogaster |
| ThreePrimeUTR | FBtr0333264-3-prime-utr | Drosophila melanogaster |
Other
54 Pathways
- PIP3 activates AKT signaling,
- Signaling Pathways,
- Insulin signaling pathway,
- PI3K Cascade,
- Signaling by ERBB2,
- Regulation of AMPK activity via LKB1,
- NGF signalling via TRKA from the plasma membrane,
- TOR signaling pathway,
- IRS-mediated signalling,
- Adaptive Immune System,
- Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R),
- PI-3K cascade,
- GAB1 signalosome,
- S6K1 signalling,
- Signaling by EGFR,
- Release of eIF4E,
- Signaling by FGFR in disease,
- IGF1R signaling cascade,
- Signaling by NGF,
- S6K1-mediated signalling,
- PI3K events in ERBB4 signaling,
- DINR-mediated activation,
- Signaling by EGFR in Cancer,
- Disease,
- Signaling by SCF-KIT,
- PI3K/AKT activation,
- AKT phosphorylates targets in the nucleus,
- IRS activation,
- DAP12 interactions,
- PI3K events in ERBB2 signaling,
- Signaling by FGFR,
- Regulation of Rheb GTPase activity by AMPK,
- Insulin receptor recycling,
- DAP12 signaling,
- Role of LAT2/NTAL/LAB on calcium mobilization,
- Downstream signal transduction,
- Signaling by ERBB4,
- Constitutive PI3K/AKT Signaling in Cancer,
- Downstream Signaling Events Of B Cell Receptor (BCR),
- B Cell Activation,
- Immune System,
- IRS-related events triggered by IGF1R,
- mTOR signalling,
- PI3K/AKT Signaling in Cancer,
- Fc epsilon receptor (FCERI) signaling,
- Signaling by PDGF,
- IRS-related events,
- mTORC1-mediated signalling,
- PKB-mediated events,
- Energy dependent regulation of mTOR by LKB1-AMPK,
- Downstream signaling of activated FGFR,
- Innate Immune System,
- Insulin receptor signalling cascade,
- Insulin receptor mediated signaling
2 Cross References
| Identifier |
Source . Name |
Subject . Primary Identifier |
|---|---|---|
| 38654 | NCBI Entrez Gene identifiers | FBgn0015806 |
| 64114 | BioGRID | FBgn0015806 |
11 Data Sets
| Name | URL |
|---|---|
| FlyBase data set for Drosophila melanogaster | |
| TrEMBL data set | http://www.ebi.ac.uk/trembl/ |
| Drosophila 12 Genomes Consortium homology | |
| GenomeRNAi data set | |
| TreeFam data set | |
| Panther data set | |
| IntAct interactions data set | |
| BioGRID interaction data set | http://www.thebiogrid.org/downloads.php |
| GO Annotation from FlyBase | |
| FlyBase fasta data set for Drosophila melanogaster | |
| Drosophila Cell Line and Developmental Stage Gene and Exon Scores |
55 Expression Scores
10 Introns
35 RNAi Results
| Screen | Gene | Phenotype | Score | Conditions | PubMed ID |
|---|---|---|---|---|---|
| Cell size regulation | S6k | none | -0.81 | 19216764 | |
| Lipid storage | S6k | none | 1.348022649 | 19067489 | |
| Lipid storage | S6k | none | 2.726643499 | 19067489 | |
| ERK signaling | S6k | ERK activation increased | moderate | 17086199 | |
| Cell morphology | S6k | Morphology | np | 14527345 | |
| Cell cycle regulation (1) | S6k | Increased G1 DNA content, decreased cell size | sp | 15616552 | |
| Cell cycle regulation (2) | S6k | Increased G1 DNA content, decreased cell size | np | 15616552 | |
| Cell size and cell-cycle regulation (1) | S6k | none | sp | 16496002 | |
| Cell size and cell-cycle regulation (1) | S6k | Decreased G2 DNA content | sp | 16496002 | |
| Cell size and cell-cycle regulation (1) | S6k | none | sp | 16496002 | |
| Cell size and cell-cycle regulation (2) | S6k | none | 1.248 | 16496002 | |
| Cell size and cell-cycle regulation (3) | S6k | none | 467 | 16496002 | |
| Candida albicans phagocytosis (1) | S6k | Decreased Candida albicans phagocytosis | np | 16336044 | |
| Candida albicans phagocytosis (2) | S6k | Decreased Escherichia coli phagocytosis | 32 | 16336044 | |
| Candida albicans phagocytosis (3) | S6k | none | 56 | 16336044 | |
| Mitochondrial biogenesis and function | S6k | Increased mitochondrial citrate synthase activity | 1.202 | 18042644 | |
| Combinatorial effect with methyl methanesulphonate (2) | S6k | Synthetic lethal with methyl methanesulphonate | sp | 19543366 | |
| Heat nociception (1) | S6k | none | -1.17 | 21074052 | |
| Heart development and function (1) | S6k | none | 1 | 20371351 | |
| Serratia marcescens infection (1) | S6k | none | 0.357142857142857 | 19520911 | |
| Notch pathway regulation (4) | S6k | Bristle morphology defects | 7 | 19363474 | |
| Akt-TOR pathway negative feedback regulation | S6k | Increased dAkt phosphorylation | 3.6 | without insulin stimulation | 20585550 |
| Actin organization and cell morphology (1) | S6k | none | np | 19265526 | |
| Actin organization and cell morphology (2) | S6k | Altered cell morphology | np | 19265526 | |
| Actin organization and cell morphology (3) | S6k | none | np | 19265526 | |
| Actin organization and cell morphology (4) | S6k | none | np | 19265526 | |
| Actin organization and cell morphology (5) | S6k | none | np | 19265526 | |
| Actin organization and cell morphology (6) | S6k | none | np | 19265526 | |
| RTK-Ras-ERK pathway regulation (1) | S6k | none | -1.15 | 10 minutes EGF stimulation | 22028469 |
| RTK-Ras-ERK pathway regulation (1) | S6k | none | -0.91 | 0 minutes EGF stimulation | 22028469 |
