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Protein : FBpp0087921 D. melanogaster

Primary Accession  ? Q24311 Organism . Name  Drosophila melanogaster
MD5 Checksum  2df26dc6266861e7dcd439fe97e2e485 UniProt Accession  Q24311
UniProt Name  CUL1_DROME GenBank Identifier  AAM68872
Is UniProt Canonical  true Is Fragment  false
Length  774 Molecular Weight  89511
Name  Cullin homolog 1 Secondary Identifier  FBpp0087921

Publication Counts Displayer

Uni Prot Comments Displayer

Protein Sequence Displayer


1 Genes

DB identifier Secondary Identifier Symbol Name Source Organism
FBgn0015509 CG1877 lin19 lin-19-like FlyBase D. melanogaster


Protein --> Gene + chromosomal location and length of the gene.


Cytoscape Network Displayer



0 Components

5 Cross References

Source . Name

Subject . Primary Identifier
NP_724623.1 RefSeq FBpp0087921
NP_724621.1 RefSeq FBpp0087921
NP_724622.1 RefSeq FBpp0087921
Dm.7926 UniGene FBpp0087921
NP_523655.1 RefSeq FBpp0087921

3 Data Sets

Name URL
FlyBase data set for Drosophila melanogaster  
Swiss-Prot data set
Reactome data set  

0 Ec Numbers

4 Locations

Located On . Primary Identifier
Start End Strand
2R 3805469 3807907 1
2R 3805469 3807907 1
2R 3805469 3807907 1
2R 3805469 3807907 1

95 Pathways

Identifier Name
96237 Double-Strand Break Repair
96074 Homologous recombination repair of replication-independent double-strand breaks
105709 Homologous Recombination Repair
78103 ATM mediated response to DNA double-strand break
29934 Circadian Clock
82742 Signaling by Wnt
81971 Degradation of beta-catenin by the destruction complex
92934 Beta-catenin phosphorylation cascade
105951 Immune System
103669 Adaptive Immune System
120473 Downstream Signaling Events Of B Cell Receptor (BCR)
120569 B Cell Activation
138322 Activation of NF-kappaB in B Cells
88681 Innate Immune System
34578 TRAF6 Mediated Induction of proinflammatory cytokines
113278 TAK1 activates NFkB by phosphorylation and activation of IKKs complex
162718 Signaling by NOTCH1 HD Domain Mutants in Cancer
162388 Signaling by NOTCH1 PEST Domain Mutants in Cancer
163048 Constitutive Signaling by NOTCH1 PEST Domain Mutants
162365 Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer
162987 Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants
162349 FBXW7 Mutants and NOTCH1 in Cancer
162508 Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant
162685 Loss of Function of FBXW7 in Cancer and NOTCH1 Signaling
112455 Mitotic M-M/G1 phases
88201 DNA Repair
112247 Cytokine Signaling in Immune system
112945 Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways
29229 NOD1/2 Signaling Pathway
91838 Toll Like Receptor TLR1:TLR2 Cascade

6 Protein Domains

DB identifier Name Short Name Type
IPR011991 Winged helix-turn-helix DNA-binding domain WHTH_DNA-bd_dom Domain
IPR019559 Cullin protein, neddylation domain Cullin_neddylation_domain Domain
IPR016158 Cullin homology Cullin_homology Domain
IPR001373 Cullin, N-terminal Cullin_N Domain
IPR016157 Cullin, conserved site Cullin_CS Conserved_site
IPR016159 Cullin repeat-like-containing domain Cullin_repeat-like_dom Domain

4 Transcripts

DB identifier Gene
FBtr0088845 lin19
FBtr0088847 lin19
FBtr0088848 lin19
FBtr0088846 lin19