Genomics
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13 Alleles
| DB identifier | Symbol | Allele Class | Organism |
|---|---|---|---|
| FBal0268402 | RpS13[dsRNA.WIZ.Scer\UAS] | Drosophila melanogaster | |
| FBal0248593 | RpS13[G8009] | Drosophila melanogaster | |
| FBal0284510 | RpS13[Scer\UAS.T:Avic\GFP] | Drosophila melanogaster | |
| FBal0064262 | RpS13[k15708] | Drosophila melanogaster | |
| FBal0064263 | RpS13[k09614] | Drosophila melanogaster | |
| FBal0048943 | RpS13[1] | loss of function allele | Drosophila melanogaster |
| FBal0104004 | RpS13[unspecified] | Drosophila melanogaster | |
| FBal0147537 | RpS13[dsRNA.cLa] | Drosophila melanogaster | |
| FBal0263132 | RpS13[HMS00135] | Drosophila melanogaster | |
| FBal0286997 | RpS13[Scer\UAS.ORF] | Drosophila melanogaster | |
| FBal0286998 | RpS13[Scer\UAS.ORF.T:Ivir\HA1] | Drosophila melanogaster | |
| FBal0208370 | RpS13[GD8007] | Drosophila melanogaster | |
| FBal0236036 | RpS13[KK109083] | Drosophila melanogaster |
363 Clones
4 Exons
| DB identifier | Symbol |
|---|---|
| FBgn0010265:4 | RpS13:4 |
| FBgn0010265:2 | RpS13:2 |
| FBgn0010265:1 | RpS13:1 |
| FBgn0010265:3 | RpS13:3 |
4 UTRs
| Class | DB identifier |
Organism . Name |
|---|---|---|
| FivePrimeUTR | FBtr0079724-5-prime-utr | Drosophila melanogaster |
| FivePrimeUTR | FBtr0100541-5-prime-utr | Drosophila melanogaster |
| ThreePrimeUTR | FBtr0079724-3-prime-utr | Drosophila melanogaster |
| ThreePrimeUTR | FBtr0100541-3-prime-utr | Drosophila melanogaster |
Other
52 Pathways
- RNA Pol II CTD phosphorylation and interaction with CE,
- Cleavage of Growing Transcript in the Termination Region,
- Formation of RNA Pol II elongation complex,
- Ribosomal scanning and start codon recognition,
- Transport of Mature Transcript to Cytoplasm,
- mRNA Processing,
- Metabolism of mRNA,
- RNA Polymerase II Transcription Elongation,
- 3' -UTR-mediated translational regulation,
- RNA Polymerase II Promoter Escape,
- SLBP independent Processing of Histone Pre-mRNAs,
- Transport of the SLBP Dependant Mature mRNA,
- Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S,
- Nonsense Mediated Decay Independent of the Exon Junction Complex,
- RNA Polymerase II Transcription Termination,
- RNA Polymerase II Transcription,
- Translation,
- SRP-dependent cotranslational protein targeting to membrane,
- Eukaryotic Translation Initiation,
- Metabolism of proteins,
- Eukaryotic Translation Elongation,
- Peptide chain elongation,
- Processing of Capped Intronless Pre-mRNA,
- Processing of Capped Intron-Containing Pre-mRNA,
- Gene Expression,
- Eukaryotic Translation Termination,
- Formation of a pool of free 40S subunits,
- Processing of Intronless Pre-mRNAs,
- GTP hydrolysis and joining of the 60S ribosomal subunit,
- Formation of the Early Elongation Complex,
- Transport of Mature mRNA Derived from an Intronless Transcript,
- Formation of the ternary complex, and subsequently, the 43S complex,
- Metabolism of RNA,
- Nonsense Mediated Decay Enhanced by the Exon Junction Complex,
- SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs,
- Translation initiation complex formation,
- Transport of Mature mRNA derived from an Intron-Containing Transcript,
- Cap-dependent Translation Initiation,
- Post-Elongation Processing of the Transcript,
- Nonsense-Mediated Decay,
- RNA Polymerase II Transcription Initiation And Promoter Clearance,
- RNA Polymerase II Transcription Pre-Initiation And Promoter Opening,
- RNA Polymerase II Pre-transcription Events,
- RNA Polymerase II Transcription Initiation,
- Transport of Mature mRNAs Derived from Intronless Transcripts,
- Elongation arrest and recovery,
- Transport of the SLBP independent Mature mRNA,
- Transcription,
- Recycling of eIF2:GDP,
- L13a-mediated translational silencing of Ceruloplasmin expression,
- Post-Elongation Processing of Intronless pre-mRNA,
- mRNA Capping
2 Cross References
| Identifier |
Source . Name |
Subject . Primary Identifier |
|---|---|---|
| 34149 | NCBI Entrez Gene identifiers | FBgn0010265 |
| 60275 | BioGRID | FBgn0010265 |
11 Data Sets
| Name | URL |
|---|---|
| FlyBase data set for Drosophila melanogaster | |
| Swiss-Prot data set | http://ca.expasy.org/sprot |
| Drosophila 12 Genomes Consortium homology | |
| GenomeRNAi data set | |
| TreeFam data set | |
| Panther data set | |
| IntAct interactions data set | |
| BioGRID interaction data set | http://www.thebiogrid.org/downloads.php |
| GO Annotation from FlyBase | |
| FlyBase fasta data set for Drosophila melanogaster | |
| Drosophila Cell Line and Developmental Stage Gene and Exon Scores |
55 Expression Scores
28 RNAi Results
| Screen | Gene | Phenotype | Score | Conditions | PubMed ID |
|---|---|---|---|---|---|
| Lipid storage | RpS13 | none | 1.519904205 | 19067489 | |
| Lipid storage | RpS13 | none | -1.278041618 | 19067489 | |
| ERK signaling | RpS13 | ERK activation reduced | weak | 17086199 | |
| Drosophila C virus infection | RpS13 | Drosophila C virus replication down | np | 17040126 | |
| Cytokinesis regulation | RpS13 | Binucleate cells with decreased viability | medium | 15547975 | |
| Drosophila C virus infection | RpS13 | Drosophila C virus infection reduced | np | 15713840 | |
| Hedgehog signaling | RpS13 | Decreased Hedgehog reporter activity | -3.24 | 16311596 | |
| Constitutive protein secretion and Golgi organization (1) | RpS13 | Decreased horseradish peroxidase protein expression | sp | 16452979 | |
| Cell size and cell-cycle regulation (1) | RpS13 | Increased G1 DNA content, decreased G2 DNA content | sp | 16496002 | |
| Cell size and cell-cycle regulation (2) | RpS13 | Decreased viability | 0.814 | 16496002 | |
| Cell size and cell-cycle regulation (3) | RpS13 | Decreased cell number | 382 | 16496002 | |
| Cell size and cell-cycle regulation (4) | RpS13 | none | below threshold | 16496002 | |
| Microtubule assembly and organization | RpS13 | none | np | 18463163 | |
| Muscle morphogenesis and function (1) | RpS13 | Lethal | np | 20220848 | |
| Muscle morphogenesis and function (2) | RpS13 | Wing posture / locomotion / ability to fly defect or lethal / semi-lethal | np | 20220848 | |
| Muscle morphogenesis and function (3) | RpS13 | none | np | 20220848 | |
| Heat nociception (1) | RpS13 | Developmentally lethal | 1.41 | 21074052 | |
| Heart development and function (1) | RpS13 | Larval lethal | 0 | 20371351 | |
| Serratia marcescens infection (1) | RpS13 | none | -0.783333333333333 | 19520911 | |
| Notch pathway regulation (4) | RpS13 | Completely lethal (pupal) | sp | 19363474 | |
| Hh pathway regulation | RpS13 | Downregulation of Hh pathway | -0.60601482086526 | 17903264 | |
| Hh pathway regulation | RpS13 | Downregulation of Hh pathway | -0.517318947324849 | 17903264 | |
| Adiposity regulation (1) | RpS13 | none | -1 | 20074523 | |
| RTK-Ras-ERK pathway regulation (1) | RpS13 | Decreased ERK phosphorylation after EGF stimulation | -5.07 | 10 minutes EGF stimulation | 22028469 |
| RTK-Ras-ERK pathway regulation (1) | RpS13 | Decreased ERK phosphorylation after EGF stimulation | -6.3 | 0 minutes EGF stimulation | 22028469 |
| RTK-Ras-ERK pathway regulation (2) | RpS13 | Increased ERK phosphorylation after sSpitz and EGF stimulation | 2.25 | 30 minutes sSpitz stimulation | 22028469 |
| RTK-Ras-ERK pathway regulation (2) | RpS13 | Increased ERK phosphorylation after sSpitz and EGF stimulation | 3.77 | 10 minutes sSpitz stimulation | 22028469 |
| Hippo pathway regulation | RpS13 | none | -2.65 | 23263283 |
