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Gene : Tfb1 D. melanogaster

DB identifier  ? FBgn0033929 Secondary Identifier  ? CG8151
Name  ? TFB1 ortholog (S. cerevisiae) Source  FlyBase
  • synonyms:
  • FBgn0010631,
  • p62,
  • CG8151,
  • FBgn0033929,
  • TFB1,
  • l(2)06949,
  • l(2)06950,
  • FBan0008151,
  • Dmp62,
  • TfBl

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9 Alleles

DB identifier Symbol Allele Class Organism
FBal0181277 Tfb1[f06697]   Drosophila melanogaster
FBal0181278 Tfb1[f03351]   Drosophila melanogaster
FBal0159671 Tfb1[EY02347]   Drosophila melanogaster
FBal0064687 Tfb1[rO238]   Drosophila melanogaster
FBal0064688 Tfb1[k06203]   Drosophila melanogaster
FBal0064689 Tfb1[06950]   Drosophila melanogaster
FBal0008121 Tfb1[06949]   Drosophila melanogaster
FBal0208771 Tfb1[GD4074]   Drosophila melanogaster
FBal0275873 Tfb1[NIG.8151R]   Drosophila melanogaster

44 Clones

Secondary Identifier DB identifier
EK272155 FBcl0023814
EK222952 FBcl0023942
EK094144 FBcl0023978
EK011444 FBcl0023994
EK307540 FBcl0024018
AT31078 FBcl0037727
bs30d04 FBcl0056077
EP14434 FBcl0087109
EP14656 FBcl0087121
GH13986 FBcl0127189
GH12038 FBcl0127213
GH22256 FBcl0127217
GM07862 FBcl0143122
GM09169 FBcl0143128
GM31535 FBcl0147792
GM25394 FBcl0147795
GM31113 FBcl0147810
LD16554 FBcl0159688
LD13344 FBcl0159691
LP06492 FBcl0188121
LP17684 FBcl0188124
RE55534 FBcl0226035
RE09735 FBcl0226044
RE71496 FBcl0226047
RE71520 FBcl0226060
RH46950 FBcl0264860
RH42046 FBcl0264868
SD27755 FBcl0289652
SD17379 FBcl0289654
SD07849 FBcl0289658

9 Exons

DB identifier Symbol
FBgn0033929:1 Tfb1:1
FBgn0033929:4 Tfb1:4
FBgn0033929:6 Tfb1:6
FBgn0033929:7 Tfb1:7
FBgn0033929:8 Tfb1:8
FBgn0033929:9 Tfb1:9
FBgn0033929:2 Tfb1:2
FBgn0033929:3 Tfb1:3
FBgn0033929:5 Tfb1:5

4 Transcripts

DB identifier Gene
FBtr0087550 Tfb1
FBtr0087549 Tfb1
FBtr0087548 Tfb1
FBtr0305616 Tfb1

8 UTRs

Class DB identifier
Organism . Name
FivePrimeUTR FBtr0087548-5-prime-utr Drosophila melanogaster
FivePrimeUTR FBtr0087549-5-prime-utr Drosophila melanogaster
FivePrimeUTR FBtr0087550-5-prime-utr Drosophila melanogaster
FivePrimeUTR FBtr0305616-5-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0087548-3-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0087549-3-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0087550-3-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0305616-3-prime-utr Drosophila melanogaster

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2 Cross References

Identifier
Source . Name

Subject . Primary Identifier
36598 NCBI Entrez Gene identifiers FBgn0033929
62348 BioGRID FBgn0033929

11 Data Sets

Name URL
FlyBase data set for Drosophila melanogaster  
Swiss-Prot data set http://ca.expasy.org/sprot
Drosophila 12 Genomes Consortium homology  
GenomeRNAi data set  
TreeFam data set  
Panther data set  
IntAct interactions data set  
BioGRID interaction data set http://www.thebiogrid.org/downloads.php
GO Annotation from FlyBase  
FlyBase fasta data set for Drosophila melanogaster  
Drosophila Cell Line and Developmental Stage Gene and Exon Scores  

55 Expression Scores


Gene . Primary Identifier

Submission . Title

Cell Line . Name

Developmental Stage . Name
Score
FBgn0033929 Drosophila Cell Line and Developmental Stage Gene and Exon Scores CME L1 1240.0
FBgn0033929 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Sg4 1348.0
FBgn0033929 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD11 982.0
FBgn0033929 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD20-c2 1132.0
FBgn0033929 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD20-c5 1520.0
FBgn0033929 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Kc167 679.0
FBgn0033929 Drosophila Cell Line and Developmental Stage Gene and Exon Scores GM2 3117.0
FBgn0033929 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S2-DRSC 1698.0
FBgn0033929 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S2R+ 1124.0
FBgn0033929 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S1 1361.0
FBgn0033929 Drosophila Cell Line and Developmental Stage Gene and Exon Scores 1182-4H 1410.0
FBgn0033929 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD16-c3 1057.0
FBgn0033929 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD32 1152.0
FBgn0033929 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD17-c3 1055.0
FBgn0033929 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD8 1717.0
FBgn0033929 Drosophila Cell Line and Developmental Stage Gene and Exon Scores CME W1 Cl.8+ 933.0
FBgn0033929 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD9 3145.0
FBgn0033929 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmBG1-c1 1691.0
FBgn0033929 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD21 1061.0
FBgn0033929 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD4-c1 1154.0
FBgn0033929 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmBG3-c2 4272.0
FBgn0033929 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S3 1384.0
FBgn0033929 Drosophila Cell Line and Developmental Stage Gene and Exon Scores CME W2 789.0
FBgn0033929 Drosophila Cell Line and Developmental Stage Gene and Exon Scores mbn2 999.0
FBgn0033929 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmBG2-c2 1204.0
FBgn0033929 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 0-2 h 1898.0
FBgn0033929 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 2-4 h 896.0
FBgn0033929 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 4-6 h 1055.0
FBgn0033929 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 6-8 h 649.0
FBgn0033929 Drosophila Cell Line and Developmental Stage Gene and Exon Scores emb 8-10h 782.0

9 Introns

DB identifier
Organism . Name
intron_FBgn0033929:3_FBgn0033929:6 Drosophila melanogaster
intron_FBgn0033929:6_FBgn0033929:7 Drosophila melanogaster
intron_FBgn0033929:7_FBgn0033929:8 Drosophila melanogaster
intron_FBgn0033929:8_FBgn0033929:9 Drosophila melanogaster
intron_FBgn0033929:2_FBgn0033929:4 Drosophila melanogaster
intron_FBgn0033929:4_FBgn0033929:6 Drosophila melanogaster
intron_FBgn0033929:1_FBgn0033929:4 Drosophila melanogaster
intron_FBgn0033929:1_FBgn0033929:5 Drosophila melanogaster
intron_FBgn0033929:5_FBgn0033929:6 Drosophila melanogaster

29 RNAi Results

Screen Gene Phenotype Score Conditions PubMed ID
Lipid storage Tfb1 none -3.961989729   19067489
Lipid storage Tfb1 none -0.018201416   19067489
ERK signaling Tfb1 ERK activation increased weak   17086199
Wnt signaling Tfb1 Increased Wnt reporter activity 3.3   15817814
Constitutive protein secretion and Golgi organization (1) Tfb1 Decreased horseradish peroxidase protein expression sp   16452979
Cell size and cell-cycle regulation (1) Tfb1 none sp   16496002
Dendrite pattern formation Tfb1 none np   16547170
Microtubule assembly and organization Tfb1 none np   18463163
Combinatorial effect with methyl methanesulphonate (1) Tfb1 Synthetic lethal with methyl methanesulphonate sp   19543366
Combinatorial effect with methyl methanesulphonate (2) Tfb1 Synthetic lethal with methyl methanesulphonate sp   19543366
Muscle morphogenesis and function (1) Tfb1 Lethal np   20220848
Muscle morphogenesis and function (1) Tfb1 none np   20220848
Heat nociception (1) Tfb1 Developmentally lethal 0   21074052
Heat nociception (1) Tfb1 none 0.49   21074052
Regulated secretory pathway biogenesis (1) Tfb1 none 7   21149569
Regulated secretory pathway biogenesis (1) Tfb1 none 0.2   21149569
Heart development and function (1) Tfb1 none 1   20371351
Serratia marcescens infection (1) Tfb1 none 0.111111111111111   19520911
Notch pathway regulation (4) Tfb1 Bristle morphology defects, notum malformation death sp   19363474
Notch pathway regulation (4) Tfb1 Bristle morphology defects, notum malformation death sp   19363474
Notch pathway regulation (1) Tfb1 Downregulation of Notch pathway np   20493818
Adiposity regulation (1) Tfb1 none -0.416   20074523
RTK-Ras-ERK pathway regulation (1) Tfb1 none -0.04 10 minutes EGF stimulation 22028469
RTK-Ras-ERK pathway regulation (1) Tfb1 none -0.64 0 minutes EGF stimulation 22028469
RTK-Ras-ERK pathway regulation (2) Tfb1 none 0.16 30 minutes sSpitz stimulation 22028469
RTK-Ras-ERK pathway regulation (2) Tfb1 none 0.51 10 minutes sSpitz stimulation 22028469
Hippo pathway regulation Tfb1 none -0.51   23263283
Srp/Lz-induced transcriptional activation Tfb1 Decreased Srp/Lz-induced transcription -4.76   20368357
Glycosylation regulation (1) Tfb1 none sp   21203496

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