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Gene : Act88F D. melanogaster

DB identifier  ? FBgn0000047 Secondary Identifier  ? CG5178
Name  ? Actin 88F Source  FlyBase
  • synonyms:
  • Ifm(3)7,
  • CG5178,
  • actin 88F,
  • FBan0005178,
  • Actin88F,
  • FBgn0000047,
  • Act88-F,
  • act 88F,
  • 88F actin,
  • Act88f,
  • Actin,
  • Arthrin,
  • Act(88F),
  • F-actin,
  • E,
  • rsd

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84 Alleles

DB identifier Symbol Allele Class Organism
FBal0248514 Act88F[R256C]   Drosophila melanogaster
FBal0000273 Act88F[7]   Drosophila melanogaster
FBal0118614 Act88F[unspecified]   Drosophila melanogaster
FBal0027955 Act88F[9]   Drosophila melanogaster
FBal0038102 Act88F[p42tK]   Drosophila melanogaster
FBal0028737 Act88F[D-1420]   Drosophila melanogaster
FBal0028735 Act88F[D-1178]   Drosophila melanogaster
FBal0028734 Act88F[D-1083]   Drosophila melanogaster
FBal0028733 Act88F[D-1020]   Drosophila melanogaster
FBal0028757 Act88F[XhoInv]   Drosophila melanogaster
FBal0028756 Act88F[XhoDel]   Drosophila melanogaster
FBal0028740 Act88F[D875]   Drosophila melanogaster
FBal0028739 Act88F[D865]   Drosophila melanogaster
FBal0028738 Act88F[D-598]   Drosophila melanogaster
FBal0028736 Act88F[D-119]   Drosophila melanogaster
FBal0028741 Act88F[E316K] antimorphic allele - genetic evidence Drosophila melanogaster
FBal0028742 Act88F[E334K] antimorphic allele - genetic evidence Drosophila melanogaster
FBal0028743 Act88F[E364K] antimorphic allele - genetic evidence Drosophila melanogaster
FBal0028745 Act88F[G366D] antimorphic allele - genetic evidence Drosophila melanogaster
FBal0028746 Act88F[G368E] antimorphic allele - genetic evidence Drosophila melanogaster
FBal0028748 Act88F[GD245] antimorphic allele - genetic evidence Drosophila melanogaster
FBal0028749 Act88F[GD245D] antimorphic allele - genetic evidence Drosophila melanogaster
FBal0028750 Act88F[GD245T] hypomorphic allele - genetic evidence Drosophila melanogaster
FBal0028753 Act88F[R372H] antimorphic allele - genetic evidence Drosophila melanogaster
FBal0028754 Act88F[V339I] antimorphic allele - genetic evidence Drosophila melanogaster
FBal0062247 Act88F[E226K] antimorphic allele - genetic evidence Drosophila melanogaster
FBal0091906 Act88F[E93K]   Drosophila melanogaster
FBal0095877 Act88F[V278T]   Drosophila melanogaster
FBal0095878 Act88F[T234S]   Drosophila melanogaster
FBal0095879 Act88F[S129T]   Drosophila melanogaster

24 Clones

Secondary Identifier DB identifier
EK103551 FBcl0057500
EK103951 FBcl0057516
GH04529 FBcl0123629
GH05190 FBcl0129597
GH08542 FBcl0129599
GH26149 FBcl0129609
GH09238 FBcl0129635
GH12863 FBcl0129637
GH01973 FBcl0129639
GH20985 FBcl0129641
LP12170 FBcl0189131
LP11613 FBcl0189146
RC0-DA0001-120700-012-F01 FBcl0361715
IP01968 FBcl0320069
IP03304 FBcl0320068
IP01966 FBcl0320070
Dmel_neb_005361_0943_3555 FBcl0369422
Dmel_dig_012832_0656_1569 FBcl0369423
Dmel_neb_010899_0665_2724 FBcl0369424
Dmel_dig_016915_0589_1890 FBcl0369425
Dmel_neb_011525_0937_1497 FBcl0369426
LD47405 FBcl0718670
CK01.169C.E6 FBcl0446218
CK01.169A.E6 FBcl0446240

3 Exons

DB identifier Symbol
FBgn0000047:2 Act88F:2
FBgn0000047:3 Act88F:3
FBgn0000047:1 Act88F:1

1 Transcripts

DB identifier Gene
FBtr0083143 Act88F

2 UTRs

Class DB identifier
Organism . Name
FivePrimeUTR FBtr0083143-5-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0083143-3-prime-utr Drosophila melanogaster

Interactions

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Other

0 Pathways

2 Cross References

Identifier
Source . Name

Subject . Primary Identifier
41885 NCBI Entrez Gene identifiers FBgn0000047
66947 BioGRID FBgn0000047

11 Data Sets

Name URL
FlyBase data set for Drosophila melanogaster  
Swiss-Prot data set http://ca.expasy.org/sprot
Drosophila 12 Genomes Consortium homology  
GenomeRNAi data set  
TreeFam data set  
Panther data set  
IntAct interactions data set  
BioGRID interaction data set http://www.thebiogrid.org/downloads.php
GO Annotation from FlyBase  
FlyBase fasta data set for Drosophila melanogaster  
Drosophila Cell Line and Developmental Stage Gene and Exon Scores  

55 Expression Scores


Gene . Primary Identifier

Submission . Title

Cell Line . Name

Developmental Stage . Name
Score
FBgn0000047 Drosophila Cell Line and Developmental Stage Gene and Exon Scores CME L1 1628.0
FBgn0000047 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Sg4 2209.0
FBgn0000047 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD11 3599.0
FBgn0000047 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD20-c2 2737.0
FBgn0000047 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD20-c5 2362.0
FBgn0000047 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Kc167 1349.0
FBgn0000047 Drosophila Cell Line and Developmental Stage Gene and Exon Scores GM2 1390.0
FBgn0000047 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S2-DRSC 1375.0
FBgn0000047 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S2R+ 770.0
FBgn0000047 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S1 1640.0
FBgn0000047 Drosophila Cell Line and Developmental Stage Gene and Exon Scores 1182-4H 1680.0
FBgn0000047 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD16-c3 7784.0
FBgn0000047 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD32 1616.0
FBgn0000047 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD17-c3 1830.0
FBgn0000047 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD8 2964.0
FBgn0000047 Drosophila Cell Line and Developmental Stage Gene and Exon Scores CME W1 Cl.8+ 1012.0
FBgn0000047 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD9 1071.0
FBgn0000047 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmBG1-c1 1181.0
FBgn0000047 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD21 2047.0
FBgn0000047 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD4-c1 1922.0
FBgn0000047 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmBG3-c2 2521.0
FBgn0000047 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S3 3587.0
FBgn0000047 Drosophila Cell Line and Developmental Stage Gene and Exon Scores CME W2 1395.0
FBgn0000047 Drosophila Cell Line and Developmental Stage Gene and Exon Scores mbn2 1204.0
FBgn0000047 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmBG2-c2 1083.0
FBgn0000047 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 0-2 h 2211.0
FBgn0000047 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 2-4 h 1428.0
FBgn0000047 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 4-6 h 2088.0
FBgn0000047 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 6-8 h 1935.0
FBgn0000047 Drosophila Cell Line and Developmental Stage Gene and Exon Scores emb 8-10h 2577.0

2 Introns

DB identifier
Organism . Name
intron_FBgn0000047:1_FBgn0000047:2 Drosophila melanogaster
intron_FBgn0000047:2_FBgn0000047:3 Drosophila melanogaster

31 RNAi Results

Screen Gene Phenotype Score Conditions PubMed ID
Lipid storage Act88F none -1.238861718   19067489
Lipid storage Act88F none -0.033616375   19067489
ERK signaling Act88F ERK activation increased weak   17086199
Cytokinesis regulation Act88F Binucleate cells with microtubule extensions medium   15547975
Cell size and cell-cycle regulation (1) Act88F none sp   16496002
Candida albicans phagocytosis (1) Act88F Decreased Candida albicans phagocytosis np   16336044
Candida albicans phagocytosis (2) Act88F Decreased Escherichia coli phagocytosis 24   16336044
Candida albicans phagocytosis (3) Act88F Decreased latex beads phagocytosis 26   16336044
Mutant human huntingtin aggregation Act88F Increased mutant human huntingtin aggregation 1.5 - 2   19789644
Muscle morphogenesis and function (1) Act88F Lethal np   20220848
Muscle morphogenesis and function (1) Act88F Lethal np   20220848
Muscle morphogenesis and function (3) Act88F Spotty (discontinuous) Z-line np   20220848
Heat nociception (1) Act88F none 1.16   21074052
Heart development and function (1) Act88F none 0.5   20371351
Serratia marcescens infection (1) Act88F none 0.588888888888888   19520911
Notch pathway regulation (4) Act88F Completely lethal (before pupal) sp   19363474
Adiposity regulation (1) Act88F none 0.319   20074523
Blood cell homeostasis regulation (1) Act88F none np   20540764
Blood cell homeostasis regulation (2) Act88F none np   20540764
S2 cell spreading Act88F none np   21041442
RTK-Ras-ERK pathway regulation (1) Act88F none -0.1 0 minutes EGF stimulation 22028469
RTK-Ras-ERK pathway regulation (1) Act88F Decreased ERK phosphorylation after EGF stimulation -1.68 10 minutes EGF stimulation 22028469
RTK-Ras-ERK pathway regulation (2) Act88F none 1.35 30 minutes sSpitz stimulation 22028469
RTK-Ras-ERK pathway regulation (2) Act88F none 1.38 10 minutes sSpitz stimulation 22028469
Wnt proteins secretion Act88F none -0.4   22094269
Wg pathway regulation (1) Act88F Decreased WgRluc and not changed sFluc protein expression weak   21886182
Hippo pathway regulation Act88F none -1.1   23263283
Muscle development and maintenance Act88F Embryo lethal sp  
Muscle development and maintenance Act88F Embryo lethal sp  
Muscle maintenance Act88F Climbing defect sp  

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