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Gene : Bx42 D. melanogaster

DB identifier  ? FBgn0004856 Secondary Identifier  ? CG8264
Name  ? Bx42 Source  FlyBase
  • synonyms:
  • FBgn0004856,
  • FBan0008264,
  • SKIP,
  • Ski-interacting protein,
  • CG8264,
  • BX42

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7 Alleles

DB identifier Symbol Allele Class Organism
FBal0162741 Bx42[f04222]   Drosophila melanogaster
FBal0187958 Bx42[dsRNA.cIa]   Drosophila melanogaster
FBal0263091 Bx42[HMS00086]   Drosophila melanogaster
FBal0141932 Bx42[dsRNA.Scer\UAS]   Drosophila melanogaster
FBal0213311 Bx42[GD13866]   Drosophila melanogaster
FBal0231376 Bx42[KK101598]   Drosophila melanogaster
FBal0275920 Bx42[NIG.8264R]   Drosophila melanogaster

70 Clones

Secondary Identifier DB identifier
DPiM_LD22701 FBcl0741423
EK113041 FBcl0117424
GM05773 FBcl0139221
GM05765 FBcl0139265
GM10374 FBcl0139283
GM24969 FBcl0144892
GM18636 FBcl0144899
HL01574 FBcl0149656
LD06993 FBcl0156672
LD15744 FBcl0156706
LD12708 FBcl0156803
LD01382 FBcl0156822
LD07579 FBcl0156926
LD11176 FBcl0156952
LD08915 FBcl0156958
LD44209 FBcl0170410
LD32559 FBcl0170450
LD33037 FBcl0170460
LD22701 FBcl0170470
LD44820 FBcl0170476
LD24432 FBcl0170495
LD38811 FBcl0170502
LD32293 FBcl0170523
LD26682 FBcl0170636
LD42216 FBcl0170792
LD25485 FBcl0170797
LD32294 FBcl0170799
LD44792 FBcl0170831
LD42231 FBcl0170869
LD35280 FBcl0170884

4 Exons

DB identifier Symbol
FBgn0004856:1 Bx42:1
FBgn0004856:4 Bx42:4
FBgn0004856:3 Bx42:3
FBgn0004856:2 Bx42:2

2 Transcripts

DB identifier Gene
FBtr0333809 Bx42
FBtr0071350 Bx42

4 UTRs

Class DB identifier
Organism . Name
FivePrimeUTR FBtr0071350-5-prime-utr Drosophila melanogaster
FivePrimeUTR FBtr0333809-5-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0071350-3-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0333809-3-prime-utr Drosophila melanogaster

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2 Cross References

Identifier
Source . Name

Subject . Primary Identifier
31840 NCBI Entrez Gene identifiers FBgn0004856
58295 BioGRID FBgn0004856

11 Data Sets

Name URL
FlyBase data set for Drosophila melanogaster  
Swiss-Prot data set http://ca.expasy.org/sprot
Drosophila 12 Genomes Consortium homology  
GenomeRNAi data set  
TreeFam data set  
Panther data set  
IntAct interactions data set  
BioGRID interaction data set http://www.thebiogrid.org/downloads.php
GO Annotation from FlyBase  
FlyBase fasta data set for Drosophila melanogaster  
Drosophila Cell Line and Developmental Stage Gene and Exon Scores  

55 Expression Scores


Gene . Primary Identifier

Submission . Title

Cell Line . Name

Developmental Stage . Name
Score
FBgn0004856 Drosophila Cell Line and Developmental Stage Gene and Exon Scores CME L1 1011.0
FBgn0004856 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Sg4 1162.0
FBgn0004856 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD11 877.0
FBgn0004856 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD20-c2 1498.0
FBgn0004856 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD20-c5 913.0
FBgn0004856 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Kc167 917.0
FBgn0004856 Drosophila Cell Line and Developmental Stage Gene and Exon Scores GM2 2495.0
FBgn0004856 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S2-DRSC 1140.0
FBgn0004856 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S2R+ 734.0
FBgn0004856 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S1 2111.0
FBgn0004856 Drosophila Cell Line and Developmental Stage Gene and Exon Scores 1182-4H 1295.0
FBgn0004856 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD16-c3 767.0
FBgn0004856 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD32 935.0
FBgn0004856 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD17-c3 1369.0
FBgn0004856 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD8 908.0
FBgn0004856 Drosophila Cell Line and Developmental Stage Gene and Exon Scores CME W1 Cl.8+ 1037.0
FBgn0004856 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD9 1734.0
FBgn0004856 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmBG1-c1 934.0
FBgn0004856 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD21 1585.0
FBgn0004856 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD4-c1 918.0
FBgn0004856 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmBG3-c2 1221.0
FBgn0004856 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S3 942.0
FBgn0004856 Drosophila Cell Line and Developmental Stage Gene and Exon Scores CME W2 851.0
FBgn0004856 Drosophila Cell Line and Developmental Stage Gene and Exon Scores mbn2 916.0
FBgn0004856 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmBG2-c2 834.0
FBgn0004856 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 0-2 h 2409.0
FBgn0004856 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 2-4 h 2356.0
FBgn0004856 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 4-6 h 2020.0
FBgn0004856 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 6-8 h 1653.0
FBgn0004856 Drosophila Cell Line and Developmental Stage Gene and Exon Scores emb 8-10h 1647.0

3 Introns

DB identifier
Organism . Name
intron_FBgn0004856:4_FBgn0004856:3 Drosophila melanogaster
intron_FBgn0004856:3_FBgn0004856:2 Drosophila melanogaster
intron_FBgn0004856:3_FBgn0004856:1 Drosophila melanogaster

28 RNAi Results

Screen Gene Phenotype Score Conditions PubMed ID
Lipid storage Bx42 Decreased lipid droplet area -2.30966616   19067489
Lipid storage Bx42 Decreased lipid droplet area -2.858110301   19067489
Lipid storage Bx42 Decreased lipid droplet area 0.274687433   19067489
Lipid storage Bx42 Decreased lipid droplet area -2.176450621   19067489
Chlamydia caviae infection Bx42 Decreased Chlamydia caviae infection np   17967059
Cytokinesis regulation Bx42 Binucleate cells with microtubule extensions weak   15547975
Intracellular Listeria monocytogenes infection Bx42 Decreased GFP protein expression moderate   16020693
Hedgehog signaling Bx42 Decreased Hedgehog reporter activity -2.95   16311596
Constitutive protein secretion and Golgi organization (1) Bx42 Decreased horseradish peroxidase protein expression sp   16452979
Cell size and cell-cycle regulation (1) Bx42 none sp   16496002
Embryonic nervous system development Bx42 Severe hypoplasia and disorganization of central nervous system and peripheral nervous system in stage-13 embryos; no embryo development beyond stage 14 np   15534205
Lipid storage Bx42 Fewer lipid droplets moderate   18408709
Mutant human huntingtin aggregation Bx42 Decreased mutant human huntingtin aggregation <= -2   19789644
Muscle morphogenesis and function (1) Bx42 none np   20220848
Notch pathway regulation (4) Bx42 none 0   19363474
Hh pathway regulation Bx42 Downregulation of Hh pathway -0.434323712022527   17903264
Hh pathway regulation Bx42 none -0.0986870804962176   17903264
Notch pathway regulation (1) Bx42 Upregulation of Notch pathway np   20493818
Notch pathway regulation (2) Bx42 Lethal very strong en-GAL4 20493818
Notch pathway regulation (2) Bx42 Downregulation of Notch pathway; adult wing margin: notches sp C96-GAL4 20493818
Notch pathway regulation (3) Bx42 Upregulation of Notch pathway np   20493818
S2 cell spreading Bx42 none np   21041442
RTK-Ras-ERK pathway regulation (1) Bx42 Decreased ERK phosphorylation after EGF stimulation -3.92 0 minutes EGF stimulation 22028469
RTK-Ras-ERK pathway regulation (1) Bx42 Decreased ERK phosphorylation after EGF stimulation -4.41 10 minutes EGF stimulation 22028469
RTK-Ras-ERK pathway regulation (2) Bx42 none -0.59 30 minutes sSpitz stimulation 22028469
RTK-Ras-ERK pathway regulation (2) Bx42 Decreased ERK phosphorylation after sSpitz and EGF stimulation -3.04 10 minutes sSpitz stimulation 22028469
Hippo pathway regulation Bx42 none -0.18   23263283
Glycosylation regulation (1) Bx42 Decreased Chp protein expression np   21203496

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