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Protein : FBpp0088375 D. melanogaster

Primary Accession  ? Q94527 Organism . Name  Drosophila melanogaster
MD5 Checksum  cc5e81281931ad821636bca0d89f3203 UniProt Accession  Q94527
UniProt Name  NFKB1_DROME GenBank Identifier  AAF54333
Is UniProt Canonical  true Is Fragment  false
Length  971 Molecular Weight  109775
Name  Nuclear factor NF-kappa-B p110 subunit Secondary Identifier  FBpp0088375

Publication Counts Displayer

Uni Prot Comments Displayer

Protein Sequence Displayer


1 Genes

DB identifier Secondary Identifier Symbol Name Source Organism
FBgn0014018 CG11992 Rel Relish FlyBase D. melanogaster


Protein --> Gene + chromosomal location and length of the gene.


Cytoscape Network Displayer



2 Components

Nuclear factor NF-kappa-B p68 subunit
Nuclear factor NF-kappa-B p49 subunit

5 Cross References

Source . Name

Subject . Primary Identifier
Dm.4154 UniGene FBpp0088375
NP_996189.1 RefSeq FBpp0088375
NP_996187.1 RefSeq FBpp0088375
NP_477094.1 RefSeq FBpp0088375
NP_996188.1 RefSeq FBpp0088375

3 Data Sets

Name URL
FlyBase data set for Drosophila melanogaster  
Swiss-Prot data set
Reactome data set  

0 Ec Numbers

3 Locations

Located On . Primary Identifier
Start End Strand
3R 4869949 4873157 -1
3R 4869949 4873157 -1
3R 4869949 4873157 -1

46 Pathways

Identifier Name
105951 Immune System
103669 Adaptive Immune System
31031 TCR signaling
34686 Downstream TCR signaling
120473 Downstream Signaling Events Of B Cell Receptor (BCR)
120569 B Cell Activation
138322 Activation of NF-kappaB in B Cells
88681 Innate Immune System
34578 TRAF6 Mediated Induction of proinflammatory cytokines
113278 TAK1 activates NFkB by phosphorylation and activation of IKKs complex
168277 FCERI mediated NF-kB activation
112247 Cytokine Signaling in Immune system
166867 Fc epsilon receptor (FCERI) signaling
167467 DEx/H-box helicases activate type I IFN and inflammatory cytokines production
120387 RIP-mediated NFkB activation via ZBP1
120480 ZBP1(DAI) mediated induction of type I IFNs
120468 Cytosolic sensors of pathogen-associated DNA
131727 TRAF6 mediated NF-kB activation
139163 RIG-I/MDA5 mediated induction of IFN-alpha/beta pathways
112945 Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways
29229 NOD1/2 Signaling Pathway
91838 Toll Like Receptor TLR1:TLR2 Cascade
109018 Toll Like Receptor 2 (TLR2) Cascade
85024 Toll Like Receptor TLR6:TLR2 Cascade
32391 Toll Like Receptor 9 (TLR9) Cascade
101443 TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation
92018 MyD88:Mal cascade initiated on plasma membrane
90914 Activated TLR4 signalling
109895 Toll Like Receptor 4 (TLR4) Cascade
87458 MyD88 dependent cascade initiated on endosome

8 Protein Domains

DB identifier Name Short Name Type
IPR002110 Ankyrin repeat Ankyrin_rpt Repeat
IPR020683 Ankyrin repeat-containing domain Ankyrin_rpt-contain_dom Domain
IPR008967 p53-like transcription factor, DNA-binding p53-like_TF_DNA-bd Domain
IPR013783 Immunoglobulin-like fold Ig-like_fold Domain
IPR014756 Immunoglobulin E-set Ig_E-set Domain
IPR002909 IPT domain IPT Domain
IPR000451 NF-kappa-B/Rel/Dorsal NF_Rel_Dor Family
IPR011539 Rel homology domain RHD Domain

3 Transcripts

DB identifier Gene
FBtr0089340 Rel
FBtr0089339 Rel
FBtr0089338 Rel