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Gene : Taf6 D. melanogaster

DB identifier  ? FBgn0010417 Secondary Identifier  ? CG32211
Name  ? TBP-associated factor 6 Source  FlyBase
  • synonyms:
  • d60,
  • TFIID,
  • TAF,
  • TAFII60(62),
  • TAF[[II]],
  • TAFII62,
  • FBgn0011301,
  • TAF60/62,
  • dme-TAFII60,
  • Taf62,
  • CG9348,
  • TAF[[II]]60/62,
  • dTAFII62,
  • CG32211,
  • dmTAF6,
  • dTAF62,
  • dTAF[[II]]62,
  • p62,
  • TBP-associated factor,
  • TAFII60,
  • dTAF[[II]]60,
  • TAF[[II]]60,
  • TAF[[II]]62,
  • TBP-associated factor 60kD,
  • l(3)76BDf,
  • TAF6,
  • TBP associated factor 60,
  • FBgn0016734,
  • FBan0032211,
  • dTAF[[II]]262,
  • TBP-Associated Factor 6,
  • SR3-4B,
  • dTAF6,
  • Taf-6,
  • FBgn0052211,
  • TAF60,
  • TFIID 62,
  • Suppressor of Ras85D 3-4B,
  • FBgn0010417,
  • TBP-associated factor 60

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18 Alleles

DB identifier Symbol Allele Class Organism
FBal0243570 Taf6[3]   Drosophila melanogaster
FBal0243571 Taf6[hs.T:Zzzz\FLAG]   Drosophila melanogaster
FBal0159686 Taf6[f06930]   Drosophila melanogaster
FBal0243572 Taf6[unspecified]   Drosophila melanogaster
FBal0264997 Taf6[B11]   Drosophila melanogaster
FBal0264998 Taf6[O29]   Drosophila melanogaster
FBal0098288 Taf6[1]   Drosophila melanogaster
FBal0048985 Taf6[XS-922] loss of function allele Drosophila melanogaster
FBal0058134 Taf6[Act5C.PF]   Drosophila melanogaster
FBal0194227 Taf6[dsRNA.cWa]   Drosophila melanogaster
FBal0194228 Taf6[dsRNA.cWb]   Drosophila melanogaster
FBal0194229 Taf6[MtnA.NTR.T:Zzzz\FLAG]   Drosophila melanogaster
FBal0194230 Taf6[MtnA.CTR.T:Zzzz\FLAG]   Drosophila melanogaster
FBal0208714 Taf6[GD10817]   Drosophila melanogaster
FBal0265675 Taf6[NIG.9348R]   Drosophila melanogaster
FBal0219553 Taf6[2]   Drosophila melanogaster
FBal0231066 Taf6[KK101106]   Drosophila melanogaster
FBal0273691 Taf6[NIG.32211R]   Drosophila melanogaster

48 Clones

Secondary Identifier DB identifier
EK151059 FBcl0136792
EK118243 FBcl0137420
EK160642 FBcl0137422
EK086209 FBcl0137424
EK143660 FBcl0137426
EK282644 FBcl0137428
EK262459 FBcl0137430
EK010862 FBcl0137434
EK176061 FBcl0137436
EK131908 FBcl0137438
EK007027 FBcl0137442
EK165158 FBcl0137450
GM02929 FBcl0140549
GM18962 FBcl0145567
LD01205 FBcl0153363
LD07223 FBcl0153365
LD10109 FBcl0153366
LD02576 FBcl0153367
LD09885 FBcl0153369
LD06463 FBcl0153370
LD03401 FBcl0153371
LD41876 FBcl0166236
LD24529 FBcl0166238
LP08015 FBcl0182060
LP18779 FBcl0182063
RE70581 FBcl0201400
RE70675 FBcl0201420
RE30331 FBcl0201446
RH68260 FBcl0247324
RH65767 FBcl0247331

8 Exons

DB identifier Symbol
FBgn0010417:9 Taf6:9
FBgn0010417:10 Taf6:10
FBgn0010417:11 Taf6:11
FBgn0010417:12 Taf6:12
FBgn0010417:13 Taf6:13
FBgn0010417:14 Taf6:14
FBgn0010417:15 Taf6:15
FBgn0010417:16 Taf6:16

2 Transcripts

DB identifier Gene
FBtr0074941 Taf6
FBtr0333272 Taf6

4 UTRs

Class DB identifier
Organism . Name
FivePrimeUTR FBtr0074941-5-prime-utr Drosophila melanogaster
FivePrimeUTR FBtr0333272-5-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0074941-3-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0333272-3-prime-utr Drosophila melanogaster

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2 Cross References

Identifier
Source . Name

Subject . Primary Identifier
40134 NCBI Entrez Gene identifiers FBgn0010417
65404 BioGRID FBgn0010417

11 Data Sets

Name URL
FlyBase data set for Drosophila melanogaster  
Swiss-Prot data set http://ca.expasy.org/sprot
Drosophila 12 Genomes Consortium homology  
GenomeRNAi data set  
TreeFam data set  
Panther data set  
IntAct interactions data set  
BioGRID interaction data set http://www.thebiogrid.org/downloads.php
GO Annotation from FlyBase  
FlyBase fasta data set for Drosophila melanogaster  
Drosophila Cell Line and Developmental Stage Gene and Exon Scores  

55 Expression Scores


Gene . Primary Identifier

Submission . Title

Cell Line . Name

Developmental Stage . Name
Score
FBgn0010417 Drosophila Cell Line and Developmental Stage Gene and Exon Scores CME L1 808.0
FBgn0010417 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Sg4 653.0
FBgn0010417 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD11 352.0
FBgn0010417 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD20-c2 571.0
FBgn0010417 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD20-c5 732.0
FBgn0010417 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Kc167 824.0
FBgn0010417 Drosophila Cell Line and Developmental Stage Gene and Exon Scores GM2 1312.0
FBgn0010417 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S2-DRSC 738.0
FBgn0010417 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S2R+ 512.0
FBgn0010417 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S1 800.0
FBgn0010417 Drosophila Cell Line and Developmental Stage Gene and Exon Scores 1182-4H 689.0
FBgn0010417 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD16-c3 481.0
FBgn0010417 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD32 396.0
FBgn0010417 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD17-c3 912.0
FBgn0010417 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD8 765.0
FBgn0010417 Drosophila Cell Line and Developmental Stage Gene and Exon Scores CME W1 Cl.8+ 555.0
FBgn0010417 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD9 932.0
FBgn0010417 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmBG1-c1 608.0
FBgn0010417 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD21 1109.0
FBgn0010417 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD4-c1 732.0
FBgn0010417 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmBG3-c2 682.0
FBgn0010417 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S3 599.0
FBgn0010417 Drosophila Cell Line and Developmental Stage Gene and Exon Scores CME W2 546.0
FBgn0010417 Drosophila Cell Line and Developmental Stage Gene and Exon Scores mbn2 508.0
FBgn0010417 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmBG2-c2 656.0
FBgn0010417 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 0-2 h 1697.0
FBgn0010417 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 2-4 h 2428.0
FBgn0010417 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 4-6 h 1753.0
FBgn0010417 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 6-8 h 1267.0
FBgn0010417 Drosophila Cell Line and Developmental Stage Gene and Exon Scores emb 8-10h 1017.0

6 Introns

DB identifier
Organism . Name
intron_FBgn0010417:9_FBgn0010417:10 Drosophila melanogaster
intron_FBgn0010417:10_FBgn0010417:11 Drosophila melanogaster
intron_FBgn0010417:11_FBgn0010417:12 Drosophila melanogaster
intron_FBgn0010417:13_FBgn0010417:14 Drosophila melanogaster
intron_FBgn0010417:14_FBgn0010417:15 Drosophila melanogaster
intron_FBgn0010417:15_FBgn0010417:16 Drosophila melanogaster

36 RNAi Results

Screen Gene Phenotype Score Conditions PubMed ID
Lipid storage Taf6 none -0.400476064   19067489
Lipid storage Taf6 none -0.05532819   19067489
Lipid storage Taf6 none 1.012616399   19067489
ERK signaling Taf6 ERK activation increased weak   17086199
Intracellular Listeria monocytogenes infection Taf6 Decreased GFP protein expression moderate   16020693
Wnt signaling Taf6 Increased Wnt reporter activity 3.6   15817814
Cell size and cell-cycle regulation (1) Taf6 none sp   16496002
Dendrite pattern formation Taf6 none np   16547170
Dendrite pattern formation Taf6 none np   16547170
Mitochondrial biogenesis and function Taf6 Decreased mitochondrial citrate synthase activity 0.791   18042644
Muscle morphogenesis and function (1) Taf6 Lethal np   20220848
Heat nociception (1) Taf6 Developmentally lethal 0   21074052
Regulated secretory pathway biogenesis (1) Taf6 none 5   21149569
Heart development and function (1) Taf6 none 0.9   20371351
Heart development and function (2) Taf6 none 2.29   20371351
Serratia marcescens infection (1) Taf6 none -0.837837837837837   19520911
Notch pathway regulation (4) Taf6 Completely lethal (pupal) sp   19363474
PGN-induced dJNK phosphorylation Taf6 Increased P-JNK protein expression with PGN 3.59 15 min PGN induction 19893628
Self-renewal and differentiation in neural stem cells Taf6 GFP aggregates number, GFP aggregates size, neuroblast less large cells, neuroblast cell shape, ganglion mother cell shorter lineages, neuroblast loss, neuroblast loss with unchanged neuroblast cell size, neuroblast underproliferation, lethal sp   21549331
Adiposity regulation (1) Taf6 none -0.366   20074523
Blood cell homeostasis regulation (1) Taf6 Increased melanotic mass formation np   20540764
Blood cell homeostasis regulation (2) Taf6 Increased melanotic mass formation np   20540764
Blood cell homeostasis regulation (3) Taf6 Increased melanotic mass formation 34.2   20540764
Blood cell homeostasis regulation (4) Taf6 none 3   20540764
Blood cell homeostasis regulation (5) Taf6 Increased melanotic mass formation 10.8   20540764
Blood cell homeostasis regulation (6) Taf6 none 0   20540764
Blood cell homeostasis regulation (7) Taf6 none 0   20540764
Blood cell homeostasis regulation (8) Taf6 Increased melanotic mass formation 22.4   20540764
RTK-Ras-ERK pathway regulation (1) Taf6 none -1.07 0 minutes EGF stimulation 22028469
RTK-Ras-ERK pathway regulation (1) Taf6 none 0.23 10 minutes EGF stimulation 22028469

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