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Gene : Hdac3 D. melanogaster

DB identifier  ? FBgn0025825 Secondary Identifier  ? CG2128
Name  ? Histone deacetylase 3 Source  FlyBase
  • synonyms:
  • dmHDA402,
  • Dromel_CG2128_FBtr0078767_hdac3_mORF,
  • Hdac 3,
  • HDAC,
  • Histone Deacetylase-3,
  • FBan0002128,
  • histone deacetylase 3,
  • FBgn0037331,
  • DHDAC3,
  • HDAC3,
  • CG2128,
  • FBgn0025825,
  • DmHDAC3

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18 Alleles

DB identifier Symbol Allele Class Organism
FBal0245689 Hdac3[JF01420]   Drosophila melanogaster
FBal0285821 Hdac3[Scer\UAS.T:SV5\V5,T:Zzzz\His6]   Drosophila melanogaster
FBal0156409 Hdac3[B]   Drosophila melanogaster
FBal0176117 Hdac3[N]   Drosophila melanogaster
FBal0263092 Hdac3[HMS00087]   Drosophila melanogaster
FBal0144842 Hdac3[Act5C.T:SV5\V5,T:Zzzz\His6]   Drosophila melanogaster
FBal0193501 Hdac3[Act5C.T:Zzzz\His6]   Drosophila melanogaster
FBal0246493 Hdac3[Scer\UAS.T:Zzzz\FLAG]   Drosophila melanogaster
FBal0246494 Hdac3[Scer\UAS.T:SV5\V5]   Drosophila melanogaster
FBal0207273 Hdac3[GD9732]   Drosophila melanogaster
FBal0207274 Hdac3[GD16563]   Drosophila melanogaster
FBal0288279 Hdac3[dsRNA.Sym.Scer\UAS]   Drosophila melanogaster
FBal0288280 Hdac3[Scer\UAS.cLa]   Drosophila melanogaster
FBal0231970 Hdac3[KK102732]   Drosophila melanogaster
FBal0245123 Hdac3[6C]   Drosophila melanogaster
FBal0245124 Hdac3[I]   Drosophila melanogaster
FBal0245125 Hdac3[J]   Drosophila melanogaster
FBal0273054 Hdac3[NIG.2128R]   Drosophila melanogaster

13 Clones

Secondary Identifier DB identifier
DPiM_LD23745 FBcl0741290
EK130060 FBcl0035982
CK00519 FBcl0059051
EP07534 FBcl0075329
LD42026 FBcl0167378
LD35677 FBcl0167676
LD46644 FBcl0167689
LD46675 FBcl0167787
LP23465 FBcl0182810
RE20551 FBcl0205697
SD27965 FBcl0277028
AT17702 FBcl0296294
65738 FBcl0464401

3 Exons

DB identifier Symbol
FBgn0025825:3 Hdac3:3
FBgn0025825:2 Hdac3:2
FBgn0025825:1 Hdac3:1

1 Transcripts

DB identifier Gene
FBtr0078767 Hdac3

2 UTRs

Class DB identifier
Organism . Name
FivePrimeUTR FBtr0078767-5-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0078767-3-prime-utr Drosophila melanogaster

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2 Cross References

Identifier
Source . Name

Subject . Primary Identifier
44446 NCBI Entrez Gene identifiers FBgn0025825
69064 BioGRID FBgn0025825

11 Data Sets

Name URL
FlyBase data set for Drosophila melanogaster  
TrEMBL data set http://www.ebi.ac.uk/trembl/
Drosophila 12 Genomes Consortium homology  
GenomeRNAi data set  
TreeFam data set  
Panther data set  
IntAct interactions data set  
BioGRID interaction data set http://www.thebiogrid.org/downloads.php
GO Annotation from FlyBase  
FlyBase fasta data set for Drosophila melanogaster  
Drosophila Cell Line and Developmental Stage Gene and Exon Scores  

55 Expression Scores


Gene . Primary Identifier

Submission . Title

Cell Line . Name

Developmental Stage . Name
Score
FBgn0025825 Drosophila Cell Line and Developmental Stage Gene and Exon Scores CME L1 550.0
FBgn0025825 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Sg4 778.0
FBgn0025825 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD11 403.0
FBgn0025825 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD20-c2 456.0
FBgn0025825 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD20-c5 701.0
FBgn0025825 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Kc167 418.0
FBgn0025825 Drosophila Cell Line and Developmental Stage Gene and Exon Scores GM2 537.0
FBgn0025825 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S2-DRSC 562.0
FBgn0025825 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S2R+ 613.0
FBgn0025825 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S1 686.0
FBgn0025825 Drosophila Cell Line and Developmental Stage Gene and Exon Scores 1182-4H 448.0
FBgn0025825 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD16-c3 491.0
FBgn0025825 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD32 685.0
FBgn0025825 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD17-c3 617.0
FBgn0025825 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD8 640.0
FBgn0025825 Drosophila Cell Line and Developmental Stage Gene and Exon Scores CME W1 Cl.8+ 478.0
FBgn0025825 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD9 589.0
FBgn0025825 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmBG1-c1 610.0
FBgn0025825 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD21 545.0
FBgn0025825 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD4-c1 506.0
FBgn0025825 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmBG3-c2 548.0
FBgn0025825 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S3 435.0
FBgn0025825 Drosophila Cell Line and Developmental Stage Gene and Exon Scores CME W2 433.0
FBgn0025825 Drosophila Cell Line and Developmental Stage Gene and Exon Scores mbn2 467.0
FBgn0025825 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmBG2-c2 396.0
FBgn0025825 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 0-2 h 923.0
FBgn0025825 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 2-4 h 866.0
FBgn0025825 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 4-6 h 503.0
FBgn0025825 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 6-8 h 466.0
FBgn0025825 Drosophila Cell Line and Developmental Stage Gene and Exon Scores emb 8-10h 490.0

2 Introns

DB identifier
Organism . Name
intron_FBgn0025825:3_FBgn0025825:2 Drosophila melanogaster
intron_FBgn0025825:2_FBgn0025825:1 Drosophila melanogaster

26 RNAi Results

Screen Gene Phenotype Score Conditions PubMed ID
Lipid storage Hdac3 none 1.949053074   19067489
Lipid storage Hdac3 none 4.976730823   19067489
Hedgehog signaling Hdac3 Decreased Hedgehog reporter activity -4.21   16311596
Cell size and cell-cycle regulation (1) Hdac3 none sp   16496002
Candida albicans phagocytosis (1) Hdac3 none np   16336044
Dendrite pattern formation Hdac3 none np   16547170
Muscle morphogenesis and function (1) Hdac3 none np   20220848
Heat nociception (1) Hdac3 Increased noxious heat avoidance 8.46   21074052
Heart development and function (1) Hdac3 none 1   20371351
Serratia marcescens infection (1) Hdac3 Decreased viability after Serratia marcescens infection -1.62857142857142   19520911
Serratia marcescens infection (2) Hdac3 none sp   19520911
Serratia marcescens infection (4) Hdac3 none sp   19520911
Notch pathway regulation (4) Hdac3 Completely lethal (pupal) sp   19363474
Hh pathway regulation Hdac3 Downregulation of Hh pathway -0.581081168433587   17903264
Hh pathway regulation Hdac3 Downregulation of Hh pathway -0.479942371850619   17903264
Pol II elongation Hdac3 Decreased Hsp70 mRNA expression 67 20 min heat shock 19279664
Notch pathway regulation (1) Hdac3 Downregulation of Notch pathway np   20493818
Notch pathway regulation (2) Hdac3 Lethal strong en-GAL4 20493818
Notch pathway regulation (2) Hdac3 none np C96-GAL4 20493818
Notch pathway regulation (2) Hdac3 Downregulation of Notch pathway; adult wing margin: notches sp C96-GAL4 20493818
Notch pathway regulation (2) Hdac3 Downregulation of Notch pathway; wing disc NRE:EGFP: down; wing disc myrRFP: reduced; lethal sp en-GAL4 20493818
Notch pathway regulation (2) Hdac3 Up- and downregulation of Notch pathway; wing disc size: overgrown; wing disc NRE:EGFP: up, gap; wing disc myrRFP: reduced; lethal sp en-GAL4 20493818
Notch pathway regulation (3) Hdac3 none np   20493818
Adiposity regulation (1) Hdac3 none 0.17   20074523
Hippo pathway regulation Hdac3 none 1.44   23263283
Glycosylation regulation (1) Hdac3 none sp   21203496

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