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Gene : Arp2 D. melanogaster

DB identifier  ? FBgn0011742 Secondary Identifier  ? CG9901
Name  ? Actin-related protein 2 Source  FlyBase
  • synonyms:
  • ARP2,
  • ARP14D,
  • Actin-related protein 14D,
  • FBan0009901,
  • FBgn0011742,
  • CG9901,
  • Actin-related protein 14 Da,
  • Actr14D

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8 Alleles

DB identifier Symbol Allele Class Organism
FBal0284222 Arp2[dsRNA.Scer\UAS.cUa]   Drosophila melanogaster
FBal0222733 Arp2[f04119]   Drosophila melanogaster
FBal0188174 Arp2[f04094]   Drosophila melanogaster
FBal0267317 Arp2[casa]   Drosophila melanogaster
FBal0242367 Arp2[JF02785]   Drosophila melanogaster
FBal0198757 Arp2[GD14716]   Drosophila melanogaster
FBal0235918 Arp2[KK108910]   Drosophila melanogaster
FBal0162793 Arp2[f04069]   Drosophila melanogaster

89 Clones

Secondary Identifier DB identifier
ESG018a.E21_H05 FBcl0005269
AT31123 FBcl0024725
AT23693 FBcl0025657
EC00438 FBcl0062561
EC00838 FBcl0067993
EP18218 FBcl0075825
EP19657 FBcl0075827
EP09213 FBcl0075831
EP05910 FBcl0075835
EP16945 FBcl0082365
GH21230 FBcl0109033
EK181952 FBcl0115412
EK165859 FBcl0115422
EK187525 FBcl0115426
EK020809 FBcl0115432
EK043832 FBcl0115470
EK043833 FBcl0115508
EK295316 FBcl0115524
EK299640 FBcl0115540
EK255764 FBcl0115556
EK165203 FBcl0115578
EK149220 FBcl0115582
EK153207 FBcl0115592
EK138154 FBcl0115618
EK059801 FBcl0115730
EK281541 FBcl0116410
EK107723 FBcl0117902
EK108323 FBcl0117906
EK237733 FBcl0119446
EK265424 FBcl0120098

11 Exons

DB identifier Symbol
FBgn0011742:9 Arp14D:9
FBgn0011742:7 Arp14D:7
FBgn0011742:6 Arp14D:6
FBgn0011742:5 Arp14D:5
FBgn0011742:4 Arp14D:4
FBgn0011742:3 Arp14D:3
FBgn0011742:2 Arp14D:2
FBgn0011742:10 Arp14D:10
FBgn0011742:11 Arp14D:11
FBgn0011742:8 Arp14D:8
FBgn0011742:1 Arp14D:1

3 Transcripts

DB identifier Gene
FBtr0310673 Arp2
FBtr0074295 Arp2
FBtr0112868 Arp2

6 UTRs

Class DB identifier
Organism . Name
FivePrimeUTR FBtr0074295-5-prime-utr Drosophila melanogaster
FivePrimeUTR FBtr0112868-5-prime-utr Drosophila melanogaster
FivePrimeUTR FBtr0310673-5-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0074295-3-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0112868-3-prime-utr Drosophila melanogaster
ThreePrimeUTR FBtr0310673-3-prime-utr Drosophila melanogaster

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2 Cross References

Identifier
Source . Name

Subject . Primary Identifier
32623 NCBI Entrez Gene identifiers FBgn0011742
58961 BioGRID FBgn0011742

11 Data Sets

Name URL
FlyBase data set for Drosophila melanogaster  
Swiss-Prot data set http://ca.expasy.org/sprot
Drosophila 12 Genomes Consortium homology  
GenomeRNAi data set  
TreeFam data set  
Panther data set  
IntAct interactions data set  
BioGRID interaction data set http://www.thebiogrid.org/downloads.php
GO Annotation from FlyBase  
FlyBase fasta data set for Drosophila melanogaster  
Drosophila Cell Line and Developmental Stage Gene and Exon Scores  

55 Expression Scores


Gene . Primary Identifier

Submission . Title

Cell Line . Name

Developmental Stage . Name
Score
FBgn0011742 Drosophila Cell Line and Developmental Stage Gene and Exon Scores CME L1 1898.0
FBgn0011742 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Sg4 1771.0
FBgn0011742 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD11 1722.0
FBgn0011742 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD20-c2 1845.0
FBgn0011742 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD20-c5 1564.0
FBgn0011742 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Kc167 2020.0
FBgn0011742 Drosophila Cell Line and Developmental Stage Gene and Exon Scores GM2 3524.0
FBgn0011742 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S2-DRSC 2242.0
FBgn0011742 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S2R+ 1548.0
FBgn0011742 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S1 1677.0
FBgn0011742 Drosophila Cell Line and Developmental Stage Gene and Exon Scores 1182-4H 2957.0
FBgn0011742 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD16-c3 1667.0
FBgn0011742 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD32 2470.0
FBgn0011742 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD17-c3 1480.0
FBgn0011742 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD8 2850.0
FBgn0011742 Drosophila Cell Line and Developmental Stage Gene and Exon Scores CME W1 Cl.8+ 2879.0
FBgn0011742 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD9 2409.0
FBgn0011742 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmBG1-c1 2051.0
FBgn0011742 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD21 2290.0
FBgn0011742 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmD4-c1 2032.0
FBgn0011742 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmBG3-c2 1520.0
FBgn0011742 Drosophila Cell Line and Developmental Stage Gene and Exon Scores S3 2398.0
FBgn0011742 Drosophila Cell Line and Developmental Stage Gene and Exon Scores CME W2 2341.0
FBgn0011742 Drosophila Cell Line and Developmental Stage Gene and Exon Scores mbn2 2060.0
FBgn0011742 Drosophila Cell Line and Developmental Stage Gene and Exon Scores ML-DmBG2-c2 1619.0
FBgn0011742 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 0-2 h 5024.0
FBgn0011742 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 2-4 h 2489.0
FBgn0011742 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 4-6 h 1956.0
FBgn0011742 Drosophila Cell Line and Developmental Stage Gene and Exon Scores Embryo 6-8 h 1681.0
FBgn0011742 Drosophila Cell Line and Developmental Stage Gene and Exon Scores emb 8-10h 1719.0

11 Introns

DB identifier
Organism . Name
intron_FBgn0011742:9_FBgn0011742:7 Drosophila melanogaster
intron_FBgn0011742:7_FBgn0011742:6 Drosophila melanogaster
intron_FBgn0011742:6_FBgn0011742:5 Drosophila melanogaster
intron_FBgn0011742:5_FBgn0011742:4 Drosophila melanogaster
intron_FBgn0011742:4_FBgn0011742:3 Drosophila melanogaster
intron_FBgn0011742:3_FBgn0011742:2 Drosophila melanogaster
intron_FBgn0011742:10_FBgn0011742:7 Drosophila melanogaster
intron_FBgn0011742:7_FBgn0011742:5 Drosophila melanogaster
intron_FBgn0011742:11_FBgn0011742:8 Drosophila melanogaster
intron_FBgn0011742:8_FBgn0011742:7 Drosophila melanogaster
intron_FBgn0011742:3_FBgn0011742:1 Drosophila melanogaster

30 RNAi Results

Screen Gene Phenotype Score Conditions PubMed ID
Lipid storage Arp2 none -1.827654681   19067489
Lipid storage Arp2 none -1.140089186   19067489
Chlamydia caviae infection Arp2 Decreased Chlamydia caviae infection np   17967059
ERK signaling Arp2 ERK activation reduced weak   17086199
Intracellular Listeria monocytogenes infection Arp2 Decreased GFP protein expression moderate   16020693
Mycobacterial infection (1) - M. fortuitum infection Arp2 Decreased M. fortuitum intracellular infection 6.8 measurement after 3 days 16020694
Mycobacterial infection (2) - E. coli phagocytosis Arp2 Decreased E. coli phagocytosis np   16020694
Cell size and cell-cycle regulation (1) Arp2 none sp   16496002
CD4 regulation by human immunodeficiency virus Type 1 Nef (HIV-1 Nef) Arp2 none 2.22   17267500
Muscle morphogenesis and function (1) Arp2 Lethal np   20220848
Muscle morphogenesis and function (1) Arp2 Lethal np   20220848
Muscle morphogenesis and function (2) Arp2 Wing posture / locomotion / ability to fly defect or lethal / semi-lethal np   20220848
Heat nociception (1) Arp2 Increased noxious heat avoidance 2.36   21074052
Heat nociception (1) Arp2 Increased noxious heat avoidance 3.64   21074052
Heat nociception (2) Arp2 none 34.33333333   21074052
Heart development and function (1) Arp2 none 1   20371351
Serratia marcescens infection (1) Arp2 none -0.176470588235294   19520911
Notch pathway regulation (4) Arp2 Loss of bristles, hair cell duplication, empty or multiple sockets, notum malformation death sp   19363474
Notch pathway regulation (4) Arp2 Completely lethal (pupal) sp   19363474
Adiposity regulation (1) Arp2 none -0.238   20074523
S2 cell spreading Arp2 Stellate morphology on Con A surface sp   21041442
RTK-Ras-ERK pathway regulation (1) Arp2 none -0.29 0 minutes EGF stimulation 22028469
RTK-Ras-ERK pathway regulation (1) Arp2 none -0.51 10 minutes EGF stimulation 22028469
RTK-Ras-ERK pathway regulation (2) Arp2 none -0.19 10 minutes sSpitz stimulation 22028469
RTK-Ras-ERK pathway regulation (2) Arp2 none -0.15 30 minutes sSpitz stimulation 22028469
Wnt proteins secretion Arp2 none 1.5   22094269
Hippo pathway regulation Arp2 none -0.86   23263283
Muscle development and maintenance Arp2 Pupal lethal sp  
Muscle maintenance Arp2 none sp  
Glycosylation regulation (1) Arp2 none sp   21203496

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